• Title/Summary/Keyword: R&D Competence

Search Result 93, Processing Time 0.024 seconds

Effects of the Oral Administration of a Probiotic Combination on the Expression of Cytokine and the Histopathology of the Large Intestine in an Animal Model of Enteritis

  • Seo, Jae-Gu;Chung, Myung-Jun;Lee, Hyun-Gi
    • Food Science of Animal Resources
    • /
    • v.32 no.2
    • /
    • pp.149-154
    • /
    • 2012
  • It is known that lactic-acid bacteria (LAB) helps keeping the intestine healthy and to enhance its immunologic competence. In addition, it is known to control the composition of the enterobacteria and the intestinal inflammatory reaction by inducing immunological enhancement. This study was performed, in a mouse model, to test the treatment and preventive effects of LAB of inflammatory bowel disease (IBD), which was induced by a blend of LAB-administering trinitrobenzene sulfonic acid (TNBS). To obtain the animal model of IBD, 2% TNBS was rectally administered once to a five-week-old male Balbc/J mouse. A probiotic combination was administered to the prevention group five times a week for eight weeks before the inducement of enteritis, and the mixture was administered to the treatment group five times a week, after the administration of TNBS. The changes in the levels of the cytokines of the lymph nodes and the tissue of the large intestine were observed, both with the naked eye and with a microscope. The observation showed that the levels of inflammatory cells, infiltration, and necrosis were much lower in the LAB-administered groups than in that of the control group. In addition, the inflammatory cytokines (e.g., TNF-${\alpha}$, IL-17A) decreased in the lymph nodes and the tissues of the large intestine. The results indicated that the administration of the combination to the animal model suppressed the inflammatory cytokines in the large intestine and in the lymph nodes, which in turn suppressed the progression of colitis.

A Study on the Effects of Entrepreneurship and Innovative Competence on Firm's Performance in Korean ICT SMEs: Focusing on Moderating Effect of Social Capital (ICT중소기업의 기업가정신과 혁신역량이 기업성과에 미치는 영향에 관한 연구: 사회적 자본의 조절효과 분석을 중심으로)

  • Roh, Doo-Hwan;Park, Ho-Young;Chang, Suk-Gwon
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.13 no.4
    • /
    • pp.217-231
    • /
    • 2018
  • In Korea, small and medium sized domestic enterprises(SMEs) play an pivotal role in the national economy, accounting for 99.8% of all enterprises, 87.9% of total employment, and 48.3% of production. and SMEs were driving a real force of the development of national economy in many respects such as innovation, job creation, industrial diversity, balanced regional development. Despite their crucial role in the national development, most of SMEs suffer from a lack of R&D capabilities and equipments as well as funding capacity. Government-Supported Research Institute(GRI) can provide SMEs with valuable supplementary technological knowledges and help them build technological capacities. so, In order to effectively support SMEs, government and GRI must be a priority to know about the factors influencing the performance related to technology transfer and technological collaborations. The purpose of this study is to analyze the influence of Innovative competences and CEO's entrepreneurship on Organizational performance in ICT small and medium enterprises, including the moderating effect of Social capital. This study adopted research variables such as Innovative competence, CEO's entrepreneurship as independent variables, with Organizational performance as a dependent variable, including the moderating variable of Social capital. 1,200 companies data which in the field of ICT SMEs were collected from the survey. The result of this empirical study is summarized as follows, First, CEO's entrepreneurship was confirmed to have a significant effect on organizational performance, and social capital variables were confirmed to have a moderating effect between entrepreneurship and organizational performance. Second, it was found that the company's Innovative competence was significantly affected the organizational performance. and also that social capital variables moderating effects. From these findings, it was confirmed that the Innovatibe competence plays an important role in influencing corporate performance.

The Effects of Internal Competence and Growth Stages on the Performance of Venture Business : the Moderating Effect in Connection with Government Funding Utilization (벤처기업의 내부역량과 성장단계가 경영성과에 미치는 영향 : 정부 지원자금 활용의 조절효과를 중심으로)

  • Kim, Yoonjung;Suh, Yoonkyo;Hong, Jungim
    • Journal of Korea Technology Innovation Society
    • /
    • v.21 no.2
    • /
    • pp.636-662
    • /
    • 2018
  • Recently, the Moon administration established the Ministry of Small and Medium-sized Enterprises (SMEs) and Startups, as part of its national strategy for start-up and innovation growth led by small and medium-sized venture companies. In a slowing economy, as venture companies with excellent internal competencies are seen to be favorable to growth, the government funding for technology development is becoming increasingly important. Previous studies examine the internal competence factors that can strengthen competitiveness through self-efforts and the influence structure of growth stage, which is an important factor in industrial environment, on business performance. As the government support for venture firms has been strengthened, the effect of government funding on the management performance and technological innovation performance of venture firms have been recently discussed in various ways. However, there is a lack of precedent research on the moderating effect of the utilization of government funding on the existing influence structure in which firm's internal competence and growth stages affects business performance. Therefore, this study examined whether the internal competencies of the venture firms and the stage of growth have direct effects on business performance and analyzed the moderating effect in connection with government funding utilization under these influence structures. The results of the study are as follows. First, the utilization of government funding in the venture firms whose R&D personnel ratio is relatively low, not to have own brands and showed an increase of employees has a significantly positive influence on business performance. Second, the moderating effects of the government funding utilization at the high growth stage of the venture firms are shown significantly. These results suggest that the venture policy linked to the job creation of the present government requires not only the support considering R&D personnel but also the necessity of supporting human resources policy to a greater extent and further study on the effectiveness of venture firms in the high growth stage.

A Policy to Improve International Competitiveness of Medium Sized Enterprises in Korea (국내 중견기업의 글로벌 경쟁력 강화 방안에 관한 연구)

  • Park, Bok Jae;Chang, Sun Mi
    • International Commerce and Information Review
    • /
    • v.16 no.3
    • /
    • pp.53-71
    • /
    • 2014
  • This study analysis the current status and policies of Korean Medium Sized Enterprises, and compared with those of U.S and Germany Recently the number of Korean Medium Sized Enterprises is highly increased. But the average sales, employment, and export which can be the indicator for growth were decreased, particularly the decrease of R&D intensity was remarkable. There are 3 policies suggestions necessary to accelerate growth of Medium Sized Enterprises. First, reform the system for Medium Sized Enterprises to grow their activity. There need to direct support as well as arrange governmental regulation. Second, need to increase R&D aid for enhance innovative competence of MSE. Lone-term continuous support for R&D is most import for promoting competitive Medium Sized Enterprises. And the lastly, for successful supporting policy there need to modify the comprehensive criterion for present Medium Sized Enterprises.

  • PDF

Lessons from Korean Innovation Model for ASEAN Countries Towards a Knowledge Economy

  • Ocon, Joey D.;Phihusut, Doungkamon;del Rosario, Julie Anne D.;Tuan, Trinh Ngoc;Lee, Jaeyoung
    • STI Policy Review
    • /
    • v.4 no.2
    • /
    • pp.19-40
    • /
    • 2013
  • The Association of Southeast Asian Nations (ASEAN) achieved relatively rapid economic growth over the past decade. Sustainable growth among member states, however, is put into question due to macroeconomic challenges, political risk, and vulnerability to external shocks. Developed countries, in contrast, have turned into less labor-intensive technologies to further expand their economies. In this paper, we review the science, technology, and innovation (STI) policies and statuses of the scientific and technological capabilities of the ASEAN member countries. Empirical results based on STI indicators (R&D spending, publications, patents, and knowledge economy indices) reveal considerable variation between the science and technology (S&T) competence and effectiveness of STI policies of ASEAN members. We have categorized nations into clusters according their situations in their S&T productivity. Under the Korean Innovation Model, Cambodia, Laos, Myanmar, and Brunei are classified as being in the institutional-building stage, while Malaysia, Thailand, Indonesia, the Philippines, and Vietnam in the catch up stage, and Singapore in the post-catch up stage. Finally, policy prescriptions on how to enhance the S&T capabilities of the developing ASEAN countries, based on the South Korea development experience, are presented.

Strategic Technology Management of Automotive Steel Sheets Makers (자동차용 강판 제조업체의 전략적 기술경영)

  • Jung, Kyung-Hee;Lee, Sang-Kyu
    • IE interfaces
    • /
    • v.16 no.3
    • /
    • pp.291-299
    • /
    • 2003
  • The managerial environment of automobile industry has been rapidly changing, mainly with the tighter standard of legal and environmental regulations, the pressure of cost reduction from the end-user, the various functional improvements of vehicles, and the globalization management. In order to survive in this complicate circumstances, the automakers have strongly pursued the mutual collaboration with the suppliers, especially tier-1, for the optimal selection of parts/materials and the assembly manufacturing processes of the new model development. They prepare the early involvement program for the suppliers during the conceptual design stage, and implement the win-win strategy of technology development activity, in order to improve the value creation. This study considers the strategic technology management of automotive steel sheets makers on the aspects of strategy, processes, human & physical resources, and organization structure. It also suggests the corporate strategies of steel mills, in order to obtain the technology competence.

Growth Strategy of PASECO as a Global Electronic Company: Focusing on the Middle East Market

  • KIM, Byoung-Goo;LEE, Chun-Su
    • East Asian Journal of Business Economics (EAJBE)
    • /
    • v.7 no.4
    • /
    • pp.27-40
    • /
    • 2019
  • Purpose - This study aims to analyze PASECO's environment and strategies during its advance into the Middle East to find out the success factors of the kerosene heater market and provide strategic implications for small and medium enterprises' growth based on these factors. Research design and methodology - This study analyzes the success factors of companies operating in the Middle East. As a case analysis study, the method of research analyzes case enterprises through existing literature, newspaper articles, and corporate interview materials. Results - PASECO's success was shown by its high technological power in kerosene heater products, understanding customers' needs, understanding the Middle East market and localization strategy. Conclusions - PASECO has been constantly developing R&D capability to secure competitive products and has released localized products to enhance the satisfaction of its customers in the Middle East and has also been successful by constantly creating new opportunities. The firm's success strategies provide implications for small and medium-sized businesses for greater growth.

신제품 개발조직의 지식역량 향상에 관한 연구

  • 김형준
    • Asia Marketing Journal
    • /
    • v.1 no.4
    • /
    • pp.47-75
    • /
    • 1999
  • 지식사회, 지식경제의 등장과 더불어 기업의 자원으로서 지식(knowledge)의 중요성이 부각됨에 따라 마케팅 전략의 한 분야로서의 신제품 전략에서도 신제품 개발과정에 있어 기업(혹은 신제품 개발 팀)의 지식과 지식의 활용 능력을 어떻게 확장할 것인가가 중요한 전략적 이슈(issue)가 된다. 신제품 개발 과정에서는 필연적으로 불확실성-시장 불확실성과 기술 불확실성-이 존재하며 불확실성을 해소하기 위하여 정보와 지식의 중요성이 부각되고 기업내의 다양한 조직-특히 R&D, 생산, 마케팅-과의 지식공유·통합과정이 중요시된다. 이에 따라 본 연구는 첫째, 기업이 가지고 있는 지식을 제품으로 구체화하는 과정이 신제품 개발(New Product Development; NPD)과정이며 구체화 과정에서 개발의 효율성과 효과성을 어떻게 달성할 것인가에 관한 문제를 다루고자 한다. 둘째, 기존의 신제품 성과 요인으로 제시되고 있는 많은 요인들을 '지식역량(knowledge competence)'의 개념으로 정리하고 이러한 지식 역량과 신제품 경쟁우위 간의 인과적 관계를 살펴봄으로써 신제품 경쟁우위에 어떠한 영향을 미치는가에 대한 분석을 하고자 한다. 셋째 신제품 개발조직의 지식역량을 향상시키기 위한 전략적 방안을 제시하고자 한다. 이론적 배경으로 기업을 지식의 결집체로 인식하고 있는 지식거점관점(knowledge based perspective)과 이러한 지식자원의 활용에 초점을 맞춘 조직학습(organizational learning) 이론 그리고 심리학에서 다루고 있는 분산된 인지이론(distributed cognition theory)을 활용한다.

  • PDF

The Influence of Focusing Manner and Emotional Labor on Nursing Performance of Clinical Nurses (임상간호사의 포커싱적 태도와 감정노동이 간호업무성과에 미치는 영향)

  • Yoo, Seung Yeon;Yu, Jung Hee
    • Journal of Korean Clinical Nursing Research
    • /
    • v.23 no.3
    • /
    • pp.341-349
    • /
    • 2017
  • Purpose: Focusing manner is very powerful mind-body self-help and self-awareness competence. So focusing manner may affect nurses' emotional labor and nursing performance, but few are known about it to date. The purpose of this study was to identify the degree of focusing manner, emotional labor, nursing performance of clinical nurses, and the factors that affect nursing performance. Methods: In order to collect data, structured questionnaires were administered to 212 nurses who worked at 2 university hospitals located in D city. Data were analyzed by t-test, ANOVA, correlation and multiple regression using SPSS/WIN 20.0. Results: Nursing performance had positive relationship with focusing manner (r=.45, p<.001), and negative relationship with emotional labor (r=-.25, p<.001). And the most prediction factor influencing nursing performance was focusing manner (${\beta}=.41$, p<.001) and the other factors were age (${\beta}=.30$, p=.002), and emotional labor (${\beta}=.14$, p=.012). The total variance was 37.1% by those predictors (F=25.87, p<.001). Conclusion: Based on the results of this study, it is necessary to develop and educational program on focusing manner-oriented psychotherapy in order to improve the nursing performance. Also, the management system for controlling emotional labor needs to be set up for nurses in clinical settings.

Development and Validation of the Communication Behavior Scale for Nurses Caring for People with Dementia (치매대상자를 돌보는 간호사의 의사소통행위 측정도구 개발 및 평가)

  • Lee, Jihye;Gang, Moonhee
    • Journal of Korean Academy of Nursing
    • /
    • v.49 no.1
    • /
    • pp.1-13
    • /
    • 2019
  • Purpose: The purpose of this study was to develop and validate the Communication Behavior Scale for nurses caring for people with Dementia (CBS-D). Methods: Based on communication accommodation theory, the initial items were generated through a literature review and interviews with 20 experts. Content and face validity of the initial items were assessed. Data from 486 nurses caring for people with dementia were analyzed using item analysis, exploratory and confirmatory factor analysis, criterion-related validity, and internal consistency. Results: The final scale consisted of 18 items and four factors (discourse response management, interpersonal control, emotional expression, and interpretability) that explained 57.6% of the variance. Confirmatory factor analysis indicated that the theoretical model with 18 items satisfied all goodness-of-fit parameters. Criterion-related validity was shown by the Global Interpersonal Communication Competence Scale (r=.506, p<.001). Cronbach's alpha for the total scale was .88. Conclusion: The CBS-D can be used to measure the communication behavior of nurses caring for people with dementia.