• Title/Summary/Keyword: R&D Centers

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A Delphi Study on National Public Vaccine Research and Development Policy in Korea (델파이기법을 활용한 국가 공공(公共)백신 연구개발 정책수립 기초조사)

  • Lee, Somin;Yeo, Sang-Gu;Kang, Shin Jung;Han, Soon Young;Lee, Sang-Won
    • Health Policy and Management
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    • v.25 no.2
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    • pp.140-148
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    • 2015
  • Vaccination is the most powerful and useful preparation against infectious diseases. However, developing vaccines costs a lot and requires extensive long-term efforts. Therefore, the government should research and develop vaccines with a national-level policy. To greatly enhance the success rate of vaccine development, the policy should be set up considering priorities such as the current status of domestic research, the importance for public health, the urgency of research. The Delphi technique was utilized to draft this survey, through a brainstorming stage, then two inquiries, and finally the final panel meeting where unresolved items were discussed, to draw the conclusion. Among the results, firstly, the highest ranked item on centralized fields for vaccine development by the Ministry of Health was 'self-sufficiency of vaccines.' Secondly, 'emerging infectious disease' was most highly ranked in prioritized fields of vaccine development and research. Thirdly, for the vaccine that needs to be improved and developed further by the government to improve its efficacy and safety, BCG (Bacille de Calmette) for tuberculosis was ranked the highest on both types (intradermal and subcutaneous injection) from National Immunization Programme (NIP) and non-NIP. As for the high risk pathogens, 'anthrax' and 'smallpox' were first and second, consecutively. Lastly, 'development and control of vaccine candidates' was ranked the highest for the area in need for technique development in order to improve domestic vaccine's research level. The results of this study will be put to good use as basic data for the national vaccine research and development (R&D) policy of the country. This study was first step and more studies should be carried out for the final decision of the national vaccine R&D priority.

Study on Indoor Air Pollutants of Public Service Centers in Winter, Seoul (서울지역 공공청사 민원실의 겨울철 실내공기질에 관한 연구)

  • Jeon, Jea-Sik;Kim, Mi-Hyung;Lee, Ju-Yeol;Jeon, Myung-Jin;Ryu, In-Cheol;Park, Duck-Shin;Choi, Han-Young
    • Journal of Korean Society for Atmospheric Environment
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    • v.27 no.5
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    • pp.569-579
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    • 2011
  • This study evaluated the indoor air quality of 26 government offices located in Seoul. The pollutant samples were taken from Jan. 13th to Jan. 29th and Feb. 20th to Feb. 23rd, 2010 in the offices. The target indoor pollutants for this study were $PM_{10}$, formaldehyde, carbon monoxide, carbon dioxide, total bacteria counts, total volatile organic compounds, radon, nitrogen dioxide, ozone, and asbestos which were controlled by the indoor air quality law for the multiple-use facilities management. The results of this study showed that some pollutants of the 38.5% offices exceeded the standards of the air quality guideline. The correlation analysis of the same pollutants between indoor and outdoor represented that $NO_2$ (r=0.629, p<0.05) and $O_3$ (r=0.459, p<0.01) were significant, however, $PM_{10}$ and CO were not. The correlation analysis between different pollutants showed that CO and TVOC (total volatile organic compounds: r=0.724; p<0.01), CO and $NO_2$ (r=0.674; p<0.01), HCHO and humidity (r=0.605; p<0.01), $CO_2$ and TVOC (r=0.534; p<0.01), TBC (total bacteria counts) and Asbestos (r=0.520; p<0.01) were significant. The energy-saving system of government buildings in winter caused under-ventilated and poor air quality. This study suggests that the concentrations of radon and $CO_2$ should be used as an indicator for monitoring indoor air quality and maintaining effective ventilations.

Selection of New High-maintenance Children's Activity Spaces based on Children's Life Patterns (어린이 활동양상 설문분석을 통한 신규관리 활동공간 검토)

  • Kim, Ho-Hyun;Choi, In-Seak;Nam, Yi-Hyun;Lee, Jeong-Hun;Yoo, Si-Eun;Park, Choong-Hee;Lee, Jung-Sub
    • Journal of Environmental Health Sciences
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    • v.45 no.2
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    • pp.164-172
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    • 2019
  • Objectives: This study's purpose is finding children's activity spaces that demand environmental safety management. Methods: The method of this study is analysing children's life patterns based on a questionnaire survey. Results: This study analyzed children's life patterns through a questionnaire survey. In total, 2,447 questionnaires were provided to analyze children's life patterns. The results of the questionnaire indicated a highly simple form because many children generally stayed in their home (66%) or nursery facility (2%). In the case of other facilities, playground was ranked first and amusement park was ranked second. In addition, kids cafe (including play facilities installed in shopping centers, etc.), library, and internet cafe were among the responses. Conclusions: The priority for new high-maintenance children's activity spaces are academy (rank 1), kids cafe (rank 2), indoor playground (rank 3).

Effect of a Finite Substrate on the Mutual Coupling of a Pair of Microstrip Patch Antennas along the H-plane (유한한 기판 크기가 H-평면상에 배열된 두 개의 패치안테나간의 상호결합에 미치는 영향)

  • Kim, Gun-Su;Kim, Tae-Young;Kim, Boo-Gyoun
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.10
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    • pp.67-73
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    • 2010
  • In this paper, the effect of a finite substrate on the mutual coupling of a pair of microstrip patch antennas along the H -plane is investigated. The mutual coupling of a pair of microstrip patch antennas can be reduced using the interference effect due to the phase difference by a variety of routes of the surface wave. In the case of the substrate with $\varepsilon_r$=10 and thickness of 3.2 mm, the mutual coupling is reduced by 4.85 dB on the substrate size with the strong mutual coupling, while the mutual coupling is reduced by 34.28 dB on the substrate size with the weak mutual coupling when the distance between the antenna centers is varied from 0.5 $\lambda_0$ to 1.0 $\lambda_0$. In the case of optimization substrate size, the decreasing rate of the mutual coupling with the increase of the distance between the antenna centers is very large. Good agreements between the image method and full wave simulation results are obtained.

생명공학 기업의 경쟁력 강화를 위한 지식인프라의 효율적 구축방안

  • 정석선;정선양
    • Proceedings of the Technology Innovation Conference
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    • 2002.06a
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    • pp.157-179
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    • 2002
  • Many advanced scholars and policy makers say that biotechnology is and will be the most important technology in 21th century. And biotechnology has a lots of character which are new and high tech industry, costing too much on early R&D stage and so on. One of them is that it can't be developed all seater by one single firm. So effective and efficient way to solve this generic problem is using the infrastructure which is given by government for flourishing the bio industry, especially, Knowledge infrastructure. The purpose of this study is to understand and give the information about which knowledge infrastructure affects biotechnology firms to obtain competitive advantage in technological improvement. To develop this object, I made 5 variables about infrastructure in biotechnology such as high-skilled researchers infrastructure, R&D policy infrastructure, industrialization infrastructure that supports the biotechnology industry, networking infrastructure between firms, universities, research centers, and finally bio-safety infrastructure. According to this study, to obtain technological competitive advantage for Korean bio firms, all main actors those are government, industry, university, research center they try to develop bio sector at the same time. After this cooperated effort, Korean bio firms and industry can get a international competitiveness in the global society which no one conquer the market.

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Influence of the Caregiver Burden on the Oral Health-related Quality of Life of the Spouse of an Elderly Person with Dementia at Home (재가 치매노인 배우자의 부양부담감이 구강건강관련 삶의 질에 미치는 영향)

  • Sung, Kiwol
    • Journal of Korean Public Health Nursing
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    • v.34 no.3
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    • pp.429-443
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    • 2020
  • Purpose: This study examined the influencing factors of caregiver burden on the oral health-related quality of life of the spouse of an elderly person with dementia at home. Methods: The participants were 115 spouses of dementia patients registered at dementia safety centers in five health centers in D city. Data were collected from June through December in 2019, using questionnaires of Oral Health Impact Profile (OHIP-49) and Burden Interview (BI). The data were analyzed using an independent t-test, one-way ANOVA, Pearson's correlation, and stepwise multiple regression analysis using the IBM SPSS Statistics 25.0 Program. Results: A negative correlation was observed between the oral health-related quality of life and caregiver burden (r=-37, p<.001). The caregiver burden (β=-.28, p=.001), subjective health status (β=.39, p<.001), and dental clinic visit (β=-.25, p=.002) explained 33.0% of the variance in the oral health-related quality of life. Conclusion: The development of nursing care for spouses of dementia patients will be needed to reduce the caregiver burden and enhance subjective health status and dental clinic visit, which influence the oral health-related quality of life of spouse of elderly people with dementia at home.

Crystallographic Studies of Dehydrated Zeolite-X Reacting with Rubidium Vapor (루비듐 증기로 처리한 탈수한 제올라이트 X의 결정학적 연구)

  • Han, Young Wook
    • Journal of the Mineralogical Society of Korea
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    • v.6 no.2
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    • pp.116-121
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    • 1993
  • A single crystla of zeolite $Na_{78}Rb_{28}-X$ (approximate composition) was prepared by exposing $Na_{92}-X$ at $350^{\circ}C$ to 0.1 Torr of rubidium vapor, and its structure was determined by single-crystal x-ray diffraction methods in the cubic space group, Fd3, ${\alpha}=25.045(4){\AA}$. The structure was refined to the final error indices $R_1=0.082$ and $R_2=0.084$ with 353 for which I>$3{\sigma}(I)$. Only about 28 of the 92 $Na^+$ ions per unit cell were reduced and only about 14 of the 28 $Na^0$ atoms produced were retained within the zeolite. A $Na_5{^{4+}}$ cluster is present within each sodalite cavity. It is a centered tetrahedron (like $CH_4$) with bond $length=2.80(2){\AA}$ and angle tetrahedral by symmetry, and shows the full symmetry of its site. $T_d$, at the center of the sodalite cavity. Each of the four terminal atoms of the $Na_5{^{4+}}$ cluster bond to three framework oxygens at $2.36(2){\AA}$. At the centers of some double 6-rings are sodium atoms which bridge linearly between $Na_5{^{4+}}$ clusters to form agglomerations such as short zig-zag chains $Na_5{^{4+}}$ clusters. Delocalized electrons, located primarily on the sodiums at centers of the sodalite and (likely) double-six-ring cavities, contribute to the stability of the clusters.

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A Strategic Approach to the Researcher Information System as Social Capital (사회적 자본으로서 연구인력정보시스템 구축에 관한 탐색적 연구)

  • Lee, Jung-Yeoun;Chung, Yeon-Kyoung;Chung, Eun-Kyung
    • Journal of the Korean Society for Library and Information Science
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    • v.43 no.3
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    • pp.59-84
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    • 2009
  • In the context of the knowledge and information society, social capital has been considered significantly in conjunction with human and physical capital. Social capital contains the social capacity which is beneficial to the efficiency and associated capital of social policies. This study aims to examine the strategic plans in order to establish researcher information systems in terms of research and development, and researcher resources at the national level. To achieve the goals of this study, firstly the current status of researcher information systems in Korea was examined. The analysis of researcher information systems includes information systems in the national R&D management institutes, the national distribution institutes, and the government funded research centers. Secondly, strategic plans for researcher information systems as social capital were discussed.

Crystal Structure of Fully Dehydrated Partially Cs+-Exchanged Zeolite X, Cs52Na40-X (The Highest Cs+-Exchanged Level Achieved by Conventional Method and Confirmation of Special Site Selectivity)

  • Bae, Myung-Nam
    • Bulletin of the Korean Chemical Society
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    • v.28 no.2
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    • pp.251-256
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    • 2007
  • The crystal structure of fully dehydrated partially Cs+-exchanged zeolite X, [Cs52Na40Si100Al92O384], a = 24.9765(10) A, has been determined by single-crystal X-ray diffraction techniques in the cubic space group Fd3 at 21 °C. The crystal was prepared by flow method for 5 days using exchange solution in which mole ratio of CsOH and CsNO3 was 1 : 1 with total concentration of 0.05 M. The crystal was then dehydrated at 400 °C and 2 × 10-6 Torr for 2 days. The structure was refined to the final error indices, R1 = 0.051 and wR2 (based on F2) = 0.094 with 247 reflections for which Fo > 4σ (Fo). In this structure, about fifty-two Cs+ ions per unit cell are located at six different crystallographic sites with special selectivity; about one Cs+ ion is located at site I, at the centers of double oxygen-rings (D6Rs), two Cs+ ions are located at site I', and six Cs+ ions are found at site II'. This is contrary to common view that Cs+ ions cannot pass sodalite cavities nor D6Rs because six-ring entrances are too small. Ring-opening by the formation of ?OH groups and ring-flexing make Cs+ ions at sites I, I', and II' enter six-oxygen rings. The defects of zeolite frameworks also give enough mobility to Cs+ ions to enter sodalite cavities and D6Rs. Another six Cs+ ions are found at site II, thirty-six are located at site III, and one is located at site III' in the supercage, respectively. Forty Na+ ions per unit cell are located at two different crystallographic sites; about fourteen are located at site I, the centers of D6Rs and twenty-six are also located at site II in the supercage. Cs+ ions and Na+ ions at site II are recessed ca. 0.34(1) A and 1.91(1) A into the supercage, respectively. In this work, the highest exchange level of Cs+ ions per unit cell was achieved in zeolite X by conventional aqueous solution methods and it was also shown that Cs+ ion could pass through the sixoxygen rings.

Life Stress, Social Support, and Antepartum Depression among Married Immigrant Women from Southeast Asia (동남아시아 결혼이주여성 임부의 생활 스트레스, 사회적 지지 및 산전우울과의 관계)

  • Shin, Hyeon Hee;Shin, Yeong Hee
    • Research in Community and Public Health Nursing
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    • v.26 no.2
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    • pp.108-118
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    • 2015
  • Purpose: The purpose of this study was to investigate life stress, social support, and antepartum depression among Southeast Asian immigrant women married to Korean men. Methods: Ninety-three subjects were recruited from local women's clinics and multicultural family support centers in D City. The instruments used were the life stress scale, social support scale, and K-EPDS. All the instruments were translated into their corresponding mother languages (Vietnamese, Cambodian, and Philippine) and notarized. Results: The item mean scores of life stress and social support were 2.65 and 3.17, respectively, on a 5-point Likert scale. The mean score of antepartum depression was 10.16, indicating that they were generally in a depressive state. A positive correlation was observed between life stress and antepartum depression (r=.59, p<.001). Social support was negatively correlated with life stress (r=-.42, p<.001) and antepartum depression (r=-.39, p<.001). The best predictors for antepartum depression were life stress, marital satisfaction, and emotional support, and they explained 43% of the variance. Conclusion: Antepartum depression in Southeast Asian immigrant brides was significantly associated with life stress as well as lack of emotional support. Emotional support may reduce their life stress and antepartum depression.