• Title/Summary/Keyword: Quantitative-Risk-Analysis

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Anesthetic efficacy of supplemental intraligamentary injection in human mandibular teeth with irreversible pulpitis: a systematic review and meta-analysis

  • Gupta, Alpa;Wadhwa, Jitesh;Aggarwal, Vivek;Mehta, Namrata;Abraham, Dax;Aneja, Kritika;Singh, Arundeep
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.22 no.1
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    • pp.1-10
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    • 2022
  • Background: Inferior alveolar nerve block (IANB) is known to have a lower success rate for anesthesia in patients with irreversible pulpitis. This calls for supplementary techniques to effectively anesthetize such patients. This systematic review aimed to evaluate the published literature for determining the success rate of anesthesia induction using post-IANB intraligamentary (IL) injection in the mandibular teeth of patients with symptomatic irreversible pulpitis. The review question was, "What is the success rate of IL injection in the mandibular teeth of patients with irreversible pulpitis as a supplementary technique for endodontic treatment?" Methods: A thorough search of electronic databases and manual searches were performed. The protocol of the review was framed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist and was registered in the International Prospective Register of Ongoing Systematic Reviews (PROSPERO) with a proper criterion for inclusion and exclusion of studies. The included studies were analyzed using the Cochrane Collaboration "Risk of Bias" tool. A meta-analysis that included a comparison of primary nerve block and supplemental IL injection was performed. The success rate was evaluated using the combined risk ratio (RR) with a random risk model. A funnel plot was created to measure publication bias. Results: After all analyses, four studies were included. In the forest plot representation, RRs were 3.56 (95% CI: 2.86, 4.44), which were in favor of the supplemental IL injections. Statistical heterogeneity was found to be 0%. These values suggest that supplemental IL injections provide better success rates for anesthesia. Conclusion: According to the pooled qualitative and quantitative analyses, supplemental IL injections increased anesthetic efficacy.

Quantitative Safety Assessment and Effectiveness Analysis for Duplication of ATS Routes (복선 항공로에 대한 정량적 안전평가 및 효과에 관한 분석)

  • Se-eun Park;Sun-min Park;Hui-yang Kim
    • Journal of Advanced Navigation Technology
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    • v.28 no.4
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    • pp.480-489
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    • 2024
  • The Ministry of Land, Infrastructure and Transport duplicated a section of ATS Route Y579 connecting Jeju and Busan in 2022 to enhance aviation safety and operational efficiency. Before duplication, an offset procedure was applied to separate aircraft flying in opposite direction by deviating them to the right of their intended flight paths. However, on December 1, 2022, this offset procedure was abolished and replaced with two parallel route, Y571(towards Busan) and Y572(towards Jeju), to improve safety and efficiency. The duplication of ATS Routes has significant implications in various aspects. This study analyzes the safety of the newly established ATS Routes and compares their safety with the previously applied offset procedure to evaluate the effectiveness of the duplication. Additionally, it presents the significance from the perspective of airspace operation. A safety assessment has conducted using a modified version of the Reich CRM (collision risk model). The analysis results confirms that the level of safety improves after the duplication and that there were benefits in terms of airspace utilization.

Case Study on the detailed standard setting and Application for QRA in Honam high speed railway tunnel (호남고속철도터널의 정량적 위험도 분석(QRA)을 위한 세부기준수립 및 적용사례)

  • Kim, Seon-Hong;Moon, Yeon-Oh;Seok, Jin-Ho;Kim, Ki-Lim;Kim, Chan-Dong;Yoo, Ho-Sik
    • Proceedings of the Korean Society for Rock Mechanics Conference
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    • 2008.10a
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    • pp.249-260
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    • 2008
  • Although the accident rate is lower than the road tunnel, fire in railway tunnel can bring large damage of human life. In the high speed railway tunnel, the possibility of the railway-disaster (fire) is growing in consideration of the speedy railway and the tunnel length. For that reason, MLTM (Ministry of Land, Transport and Maritime Affairs) published "Rules about the Safety Standard of Railroad (2005.10.27)" and "The Detailed Safety Standard of Railroad (2006.9.22)". According to those, QRA(Quantitative Risk Analysis) technique is recommended to be applied to railway tunnel design which is longer than 1km for assuring the safety function and estimating the risk. However, it is difficult to perform the disaster prevention design due to lack of the detailed standards about event scenario, fire intensity, incidence rate of accidents etc. Therefore, This paper introduces the case of tunnel design for disaster prevention of the Honam high speed railway including the detailed standards of QRA and reasonable safety facilities.

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The hierarchical structures of cause-and-effect relationships on the profit factors in overseas construction projects (해외건설공사 수익성 영향인자의 계층구조 및 사레적용에 관한 연구)

  • Han, Seung-Heon;Sun, Seung-Min;Park, Sang-Hyuk;Jung, Do-Young
    • Korean Journal of Construction Engineering and Management
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    • v.7 no.5
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    • pp.64-76
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    • 2006
  • Korea's overseas construction industry has been rather depressed by the weakened profitability as well as the sharp decrease of the market shares due to the lack of international competitiveness and the declined international market. There exist a lot of various risks in performing the overseas construction, and especially EPC projects, which entail complicated process from different parts, also require a sophisticated procurement and management skill. Subsequently, to survive in the competitive international market, we need to establish strategies to select potentially profitable projects at the initial stage of bidding process and to mitigate the high degree of risk exposure through contract negotiation and its adjustment. This research discusses the trend of environment in international construction markets. Then, it identifies the key factors that affect the profitability significantly through the structured surveys from 59 actual overseas projects, and it analyzes the key factors by using statistical methods. This research provides the profitability evaluation bases, with which overseas construction participants can forecast and analyze the risk more systematically, by eliciting profit-influencing factors using the result of statistical analysis, literature review and structuring their cause-and-effect relationships. The profitability casual hierarchy structure describes the profitability factors' hierarchy in details and their interrelationships. It also enables us to find out critical factors directly related to profitability aggravation through a qualitative and quantitative analysis. Ultimately, with this hierarchy structure as the base, the research will suggest how to develop the quantitative profitability forecasting model.

Analysis of Damage Impact Range according to the NG/NH3 Mixing Ratio when applying Ammonia as Fuel for a Combined Cycle Power Plant using an ALOHA Program (ALOHA 프로그램을 활용한 복합화력발전소 내 암모니아 연료 적용 시 NG/NH3 혼소율에 따른 피해영향범위 분석)

  • Yoo Jeong Choi;Hee Kyung Park;Min Chul Lee
    • Journal of the Korean Institute of Gas
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    • v.28 no.1
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    • pp.73-84
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    • 2024
  • In this study, a quantitative risk impact assessment is performed using an ALOHA program to identify the risks when applying ammonia as fuel for combined cycle power plants as one of the solutions of climate change. The worst and the alternative accident scenarios are established for the Sejong combined cycle power plant and the effective ranges are calculated in terms of flammability, thermal radiation, overpressure and toxicity. The analysis results show that the toxic risk is the most critical and the effective distance is highly proportional to the mixing ratio of natural gas and ammonia by showing the Pearson's correlation coefficient over 98% as 0.991, 0.987 and 0.989 for the Level Of Concern(LOC)-1, LOC-2 and LOC-3, respectively. In addition, the coefficients of linearity for LOC-1, LOC-2 and LOC-3 are calculated to 133, 70 and 29, respectively so it can be confirmed that the effective distance increases as the criterion decreases.

Study on the Methodology of the Microbial Risk Assessment in Food (식품중 미생물 위해성평가 방법론 연구)

  • 이효민;최시내;윤은경;한지연;김창민;김길생
    • Journal of Food Hygiene and Safety
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    • v.14 no.4
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    • pp.319-326
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    • 1999
  • Recently, it is continuously rising to concern about the health risk being induced by microorganisms in food such as Escherichia coli O157:H7 and Listeria monocytogenes. Various organizations and regulatory agencies including U.S.FPA, U.S.DA and FAO/WHO are preparing the methodology building to apply microbial quantitative risk assessment to risk-based food safety program. Microbial risks are primarily the result of single exposure and its health impacts are immediate and serious. Therefore, the methodology of risk assessment differs from that of chemical risk assessment. Microbial quantitative risk assessment consists of tow steps; hazard identification, exposure assessment, dose-response assessment and risk characterization. Hazard identification is accomplished by observing and defining the types of adverse health effects in humans associated with exposure to foodborne agents. Epidemiological evidence which links the various disease with the particular exposure route is an important component of this identification. Exposure assessment includes the quantification of microbial exposure regarding the dynamics of microbial growth in food processing, transport, packaging and specific time-temperature conditions at various points from animal production to consumption. Dose-response assessment is the process characterizing dose-response correlation between microbial exposure and disease incidence. Unlike chemical carcinogens, the dose-response assessment for microbial pathogens has not focused on animal models for extrapolation to humans. Risk characterization links the exposure assessment and dose-response assessment and involve uncertainty analysis. The methodology of microbial dose-response assessment is classified as nonthreshold and thresh-old approach. The nonthreshold model have assumption that one organism is capable of producing an infection if it arrives at an appropriate site and organism have independence. Recently, the Exponential, Beta-poission, Gompertz, and Gamma-weibull models are using as nonthreshold model. The Log-normal and Log-logistic models are using as threshold model. The threshold has the assumption that a toxicant is produce by interaction of organisms. In this study, it was reviewed detailed process including risk value using model parameter and microbial exposure dose. Also this study suggested model application methodology in field of exposure assessment using assumed food microbial data(NaCl, water activity, temperature, pH, etc.) and the commercially used Food MicroModel. We recognized that human volunteer data to the healthy man are preferred rather than epidemiological data fur obtaining exact dose-response data. But, the foreign agencies are studying the characterization of correlation between human and animal. For the comparison of differences to the population sensitivity: it must be executed domestic study such as the establishment of dose-response data to the Korean volunteer by each microbial and microbial exposure assessment in food.

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A Quantitative Analysis Theory for Reliability of Software (소프트웨어 신뢰성의 정량적 분석 방법론)

  • Cho, Yong-Soon;Youn, Hyun-Sang;Lee, Eun-Seok
    • Journal of KIISE:Computing Practices and Letters
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    • v.15 no.7
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    • pp.500-504
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    • 2009
  • A reliability of software is a type of nonfunctional requirement. Traditionally, a validation of the reliability is processed at the integration phase in software development life cycle. However, it increases the cost and the risk for the development. In this paper, we propose reliability analysis method based on mathematical analytic model at the architecture design phase of the development process as follows. First, we propose the software modeling methodology for reliability analysis using Hierarchical combined Queueing Petri Nets(HQPN). Second, we derive the Markov Reward Model from the HQPN based model. We apply our approach to the video conference system to verify the usefulness of our approach. Our approach supports quantitative evaluation of the reliability.

Analysis of Radioactivity Concentrations in Cigarette Smoke and Tobacco Risk Assessment (담배연기와 담뱃잎 내 함유된 방사능 농도분석 및 위해도 평가)

  • Lee, Se-Ryeong;Lee, Sang-Bok;Kim, Jeong-Yoon;Kim, Ji-Min;Bang, Yei-jin;Lee, Doo-Seok;Jo, Hyung-Joon;Kim, Sungchul
    • Journal of radiological science and technology
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    • v.44 no.5
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    • pp.489-494
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    • 2021
  • In this study, radioactivity quantitative analysis was performed on radon contained in cigarette, and the effective dose was calculated using the result value to determine the amount of exposure caused by smoking. A total of 5 types of cigarettes were sampled. Cigarette smoke was collected by using activated carbon, and tobacco were measured by homogenizing for quantitative analysis. For each sample, Bi-214 and Pb-214 were subjected to gamma nuclide analysis to observe the uranium-based radioactive material contained in cigarette, and a measurement time of 30,000 seconds was set for the sample based on the results of previous studies. As a result of measuring the radioactivity of tobacco, a maximum of 0.715 Bq/kg was derived, and in the case of cigarette smoke measured using activated carbon, a maximum of 3.652 Bq/kg was derived. Using this measurement, the average effective dose to the lungs is 0.938 mSv/y, and it was found that there is a possibility of receiving exposure up to 1.099 mSv/y depending on the type of tobacco. It was found that the exposure dose due to cigarette occupies a large proportion of the annual effective dose limit for the general public. Therefore, more diverse studies on radioactive substances in cigarette are needed, and measures to monitor and reduce the incidental exposure to radon should be established.

A Review of Quantitative Landslide Susceptibility Analysis Methods Using Physically Based Modelling (물리사면모델을 활용한 정량적 산사태 취약성 분석기법 리뷰)

  • Park, Hyuck-Jin;Lee, Jung-Hyun
    • The Journal of Engineering Geology
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    • v.32 no.1
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    • pp.27-40
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    • 2022
  • Every year landslides cause serious casualties and property damages around the world. As the accurate prediction of landslides is important to reduce the fatalities and economic losses, various approaches have been developed to predict them. Prediction methods can be divided into landslide susceptibility analysis, landslide hazard analysis and landslide risk analysis according to the type of the conditioning factors, the predicted level of the landslide dangers, and whether the expected consequence cased by landslides were considered. Landslide susceptibility analyses are mainly based on the available landslide data and consequently, they predict the likelihood of landslide occurrence by considering factors that can induce landslides and analyzing the spatial distribution of these factors. Various qualitative and quantitative analysis techniques have been applied to landslide susceptibility analysis. Recently, quantitative susceptibility analyses have predominantly employed the physically based model due to high predictive capacity. This is because the physically based approaches use physical slope model to analyze slope stability regardless of prior landslide occurrence. This approach can also reproduce the physical processes governing landslide occurrence. This review examines physically based landslide susceptibility analysis approaches.

Discussion for Improvement of Decision System of Total Risk in Off-site Risk Assessment (화학사고 장외영향평가 제도의 종합위험도 결정 체계 개선을 위한 고찰)

  • Choi, Woosoo;Ryu, Taekwon;Kwak, Sollim;Lim, Hyeongjun;Jung, Jinhee;Lee, Jieun;Kim, Jungkon;Baek, Jongbae;Yoon, Junheon;Ryu, Jisung
    • Journal of Environmental Health Sciences
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    • v.44 no.3
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    • pp.217-226
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    • 2018
  • Objectives: Despite the positive effects of Off-site risk assessment (ORA) system such as prevention of chemical accidents, some problems have been constantly raised. The purpose of this study is to analyze the problems that have occurred through the implementation of the ORA system for the past three years and to suggest reasonable directions for improvement in the future. Methods: In order to identify the problems with the methodology and procedure of ORA system, we analyzed statutes, administrative rules and documents related to the ORA system. A survey of ORA reviewers in National Institute of Chemical Safety was conducted to investigate the weight of determinants considered when judging the level of total risk in ORA. Results: In this study, we found out the uncertainty of the estimation of the number of people in the impact range in the procedure of the risk assessment of individual handling facilities, the lack of quantitative risk analysis methods for environmental receptors, and the ambiguity of the criteria for the total risk. In addition to suggesting solutions to the problems mentioned above, we also, suggested a decision tree for total risk in ORA. Conclusion: We anticipate that the solutions including the systematic decision tree for total risk suggested will contribute to the smooth operation of the ORA system.