• 제목/요약/키워드: Quantitative risk

검색결과 1,143건 처리시간 0.027초

Epidemiologic Trends and Aspects of Severe Fever with Thrombocytopenia Syndrome Outbreaks in Korea and Japan, 2013~2017

  • Lee, Won-Chang;Park, Seung-Yong;Choe, Nong-Hoon;Kwon, Young Hwan
    • 항공우주의학회지
    • /
    • 제30권2호
    • /
    • pp.75-79
    • /
    • 2020
  • This study focuses on the comparative and quantitative analysis of the epidemiologic trends and aspects of severe fever with thrombocytopenia syndrome (SFTS) outbreaks between Korea and Japan from 2013 to 2017. The following factors were analyzed; cumulative incidence rate (CIR), cases-fatality rate (CFR), and the epidemic aspects, including cases related to gender, male-to-female morbidity ratio (MFMR), age, seasonal, and geographical distributions. We observed 607 SFTS cases with CIR in Korea during the period 2013 to 2017 were as 0.24 per 100,000 populations and with a 127 fatal-cases (F.C.s), corresponding to a CFR of 20.9%, respectively. During the same period in Japan, 319 SFTS cases with a CIR of 0.05 and with 60 F.C.s to a CFR of 18.8% observed. When compared, the CIR of SFTS in Korea was significantly higher than in Japan (P<0.01), but there were no significant differences levels of the CFR and MFMR between Korea and Japan. Also, a higher incidence of SFTS was observed in people aged over 50-years or elders in Korea and those of 60-years or elders in Japan (P<0.01). The seasonal distribution of SFTS outbreak cases showed that the incidence in summer through autumn in Korea (92.4% of total cases) was higher than in Japan (65.2%), while the outbreaks of SFTS in spring was much higher in Japan (31.0%) than in Korea (7.4%), (P<0.01). The regional distribution revealed no significant difference between the eastern area (44.8%) and the western area (46.8%) of the Korean peninsula except Jeju-island (8.4%). However, in Japan, the incidence only occurred in Chubu-Kinki-Chugoku (30.3%), Shikoku (25.7%), Kyushu (42.6%) and Okinawa (0.3%), which are the western and southern areas of Japan. These differences in SFTS occurrence may reflect the influences of vector/hosts, climate, and geographical and cultural characteristics between the two countries.

패션폐기물의 공공분리배출과 순환패션제품에 대한 소비자의 인식과 영향요인 (Factors affecting consumers' perceptions of the public recycling of fashion waste and circular fashion products)

  • 석효정
    • 복식문화연구
    • /
    • 제31권2호
    • /
    • pp.141-160
    • /
    • 2023
  • Controlling fashion waste throughout the entire product lifecycle is critical in a circular economy. This study explored the possibility of establishing a public recycling system for fashion waste. Since consumer interests and participation are essential, theoretical research, social-text analysis, and quantitative research were conducted to identify consumers' perceptions of the public recycling of fashion waste and circular fashion. Data were collected via an online survey among women in their 20-30's living in Korea, and 304 samples were used for data analysis. The results were as follows. First, consumers' perceptions of recycling fashion waste were composed of recycling difficulty, the need for public recycling, and the need for EPR. Circular fashion perception comprised favor, environment protection, attractiveness, economics, quality and hygiene risks, and lack of diversity. Second, the reuse-recycle attitude and need for EPR affected the favor of all types of circular fashion products. Third, environmental concerns impacted attractiveness, and the favor significantly affected the purchase intention of all types of circular fashion products. In particular, quality and hygiene risk negatively affected the purchase intention of used-fashion products, while attractiveness positively impacted the purchase intention of upcycled-fashion products. The results implied that discussing the public recycling system of fashion waste and EPR policy is imperative. The results also showed the need to classify different types of circular fashion products, such as used, upcycled, and regenerated fashion items, to examine consumers' perceptions. In addition, the recycling of the fashion waste scale developed in this study could be used for further research.

Preconception care knowledge and information delivery modes among adolescent girls and women: a scoping review

  • Wiwit Kurniawati;Yati Afiyanti;Lina Anisa Nasution;Dyah Juliastuti
    • 여성건강간호학회지
    • /
    • 제29권1호
    • /
    • pp.12-19
    • /
    • 2023
  • Purpose: The aim of this study was to conduct a scoping review of knowledge and information delivery modes related to preconception care (PCC) among adolescent girls and women. Methods: A scoping review was performed on studies selected from five electronic databases (Cochrane Library, PubMed, Science Direct, CINAHL/EBSCO, and ProQuest), published between 2012 and 2022, with predetermined keywords and criteria. We included English-language research articles available in full text and excluded irrelevant articles. Results: This study included eight articles, comprising seven quantitative studies and one qualitative study conducted among adolescent girls and women. Five were from low- and middle-income countries and three were from high-income countries. The synthesized themes generated from the data were PCC knowledge and PCC information delivery modes and effectiveness. In general, adolescent girls and women were found to have basic PCC knowledge, including risk prevention and management and a healthy lifestyle, although more extensive knowledge was found in higher-income countries than in lower-income countries. The delivery modes of PCC information have grown from individual face-to-face conventional methods, which are used predominantly in lower-income countries, to more effective digital mass media. Conclusion: Globally, many women still have insufficient knowledge regarding PCC, as not all of them receive access to PCC information and support. PCC promotion efforts should be initiated earlier by involving a wider group of reproductive-age women and combining individual, in-group, face-to-face, and electronic delivery modes.

ESG 안전 평가지표 개발에 관한 연구 (A Study on the Development of ESG Safety Evaluation Index)

  • 윤철희;이근원;정승호
    • 한국가스학회지
    • /
    • 제27권2호
    • /
    • pp.16-24
    • /
    • 2023
  • 산업에서 발생할 수 있는 각종 위험을 발굴하고 제어하는 리스크관리에서 기업의 지속 가능한 발전을 목표로 ESG(환경·사회·지배구조)경영을 도입하고 있다. 앞으로는 기업 지속가능성에 대한 가치 판단 도구로써 ESG 평가가 더욱 활용될 것이다. 이러한 ESG 평가를 활용하여 기업의 사고 예방 정도를 관리하고 있다. 현행 ESG 평가체계에 대한 형태소 분석을 통하여 안전에 대한 평가항목을 분석하여, ESG에서 활용 가능한 정량적 '안전평가지표'가 미흡함을 알았다. 본 연구에서는 국내외 산업 사고 데이터를 분석하고 집중 관리가 필요한 '사고 기여 인자'를 도출했으며, 해당 결과를 기반으로 보완이 필요한 주요 안전관리 항목을 선정했다. 선정한 항목들은 '사고 예방 관리'에 적합한 평가 요소로 최적화시키는 과정을 거쳐, ESG 안전 평가지표를 개발하였다.

지역별 홍수피해특성을 고려한 홍수피해지표 개발 (Flood Damage Index regarding Regional Flood Damage Characteristics)

  • 박태선;여창건;최민하;이승오
    • 대한토목학회논문집
    • /
    • 제30권4B호
    • /
    • pp.361-366
    • /
    • 2010
  • 시군구간의 잠재적 홍수피해 위험성을 계량적으로 비교할 수 있다면 지역단위의 치수계획을 수립하거나 국가의 치수예산 집행 우선순위를 결정하는데 큰 도움이 된다. 본 연구에서는 지역별 홍수피해의 잠재적 위험성을 손쉽게 파악할 수 있는 홍수피해지표(Flood Damage Index : FDI)를 제안하였다. 홍수피해지표는 홍수피해에 영향을 미치는 직 간접적 요인들을 자연적 요인, 사회적 요인, 정책적 요인, 시설적 요인이라는 네 가지로 구분한 후, 이들을 대표하는 11개 주요 인자들을 선정하고, 인자별 가중치와 무차원 인자값들을 곱하여 합산한 지표이다. 이 지표를 이용하여 전국 229개 시군구의 잠재적 홍수피해 위험성을 비교하였고, 지역별 홍수발생요인도 분석하였다. 연구결과는 보다 합리적인 치수대책수립에 활용될 수 있다.

Rapid Detection of Streptococcus mutans Using an Integrated Microfluidic System with Loop-Mediated Isothermal Amplification

  • Jingfu Wang;Jingyi Wang;Xin Chang;Jin Shang;Yuehui Wang;Qin Ma;Liangliang Shen
    • Journal of Microbiology and Biotechnology
    • /
    • 제33권8호
    • /
    • pp.1101-1110
    • /
    • 2023
  • Streptococcus mutans is the primary causative agent of caries, which is one of the most common human diseases. Thus, rapid and early detection of cariogenic bacteria is critical for its prevention. This study investigated the combination of loop-mediated isothermal amplification (LAMP) and microfluid technology to quantitatively detect S. mutans. A low-cost, rapid microfluidic chip using LAMP technology was developed to amplify and detect bacteria at 2.2-2.2 × 106 colony-forming units (CFU)/ml and its detection limits were compared to those of standard polymerase chain reaction. A visualization system was established to quantitatively determine the experimental results, and a functional relationship between the bacterial concentration and quantitative results was established. The detection limit of S. mutans using this microfluidic chip was 2.2 CFU/ml, which was lower than that of the standard approach. After quantification, the experimental results showed a good linear relationship with the concentration of S. mutans, thereby confirming the effectiveness and accuracy of the custom-made integrated LAMP microfluidic system for the detection of S. mutans. The microfluidic system described herein may represent a promising simple detection method for the specific and rapid testing of individuals at risk of caries.

Efficacy of Acupuncture for Parkinson's Disease over the Last Decade: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Yeonju Kim;Yigun Lim;Subin Ahn;Junyeop Oh;Yoonbyeong Chae;Yoomin Choi;Jong Uk Kim
    • Journal of Acupuncture Research
    • /
    • 제41권1호
    • /
    • pp.29-52
    • /
    • 2024
  • The aim of this review is to consolidate findings from clinical investigations spanning the past decade regarding the impact of acupuncture on Parkinson's disease (PD). The objective is to assess the efficacy of acupuncture as a therapeutic approach to PD, with the intention of informing future clinical practices and advancing the foundation for subsequent research endeavors in this area. A comprehensive literature search was conducted to identify clinical trials exploring the effects of acupuncture on PD between January 2014 and August 2023. Databases search included PubMed, EMBASE, CNKI, OASIS, KISS, KMBASE, RISS, and ScienceON. Quantitative evidence from randomized controlled trials (RCTs) was systematically reviewed, and the methodological quality of the included studies was assessed using Cochrane's risk of bias tool. Meta-analysis was performed using Review Manager (RevMan) 5.4.1 software. The systematic review encompassed a total of 38 RCTs involving 2,786 participants. Meta-analysis of 12 studies revealed that individuals treated with a combination of acupuncture and Western medicine exhibited notable improvements compared to those receiving Western medicine alone or sham acupuncture alongside Western medicine. However, the overall quality of the RCTs was deemed low, and no serious adverse events were reported. Across clinical investigations conducted in the past decade, acupuncture appears to hold promise as a complementary treatment for PD patients when administered alongside Western medicine. Nevertheless, this study identifies certain limitations that warrant consideration in future research endeavors. Enhanced emphasis on conducting high-quality RCTs is imperative to comprehensively evaluate the efficacy of acupuncture in managing PD.

Impingement wastage experiment with SUS 316 in a printed circuit steam generator

  • Siwon Seo;Bowon Hwang;Sangji Kim;Jaeyoung Lee
    • Nuclear Engineering and Technology
    • /
    • 제56권1호
    • /
    • pp.257-264
    • /
    • 2024
  • The sodium cooled fast reactor (SFR) is one of the Gen-IV reactors with the most operating experience accumulated. Although the technology level is the most mature among the Gen-IV reactors, there is still a safety problem that has not been solved, which is the sodium-water reaction. Since sodium and water are separated only by a heat transfer tube with a thickness of only a few mm, there is inherently a risk of a sodium-water reaction (SWR) accident in the SFR. In this study, it is attempted to quantitatively evaluate the resistance of SWR accidents by replacing the shell and tube steam generator with printed circuit steam generator (PCSG) as a method to mitigate the SWR accident. To do this, a CATS-S (Compact Accident Tolerance Steam Generator-SWR) facility was designed and built. And for the quantitative evaluation of accident resistance, a methodology for measuring the impingement wastage rate was established. As a result of this research, the impingement wastage rate caused by SWR generated in a PCSG was measured first time. It was confirmed that the impingement wastage phenomenon was suppressed in the PCSG, and the accident resistance was higher than that of the SWR through comparison with the experimental results performed in the existing shell and tube steam generator. In conclusion, a PCSG is more resistant to impingement wastage as a result of the SWR accident than existing shell and tube steam generators, and it is estimated that a PCSG can mitigate SWR accidents, an inherent problem of SFR.

Software Metric for CBSE Model

  • Iyyappan. M;Sultan Ahmad;Shoney Sebastian;Jabeen Nazeer;A.E.M. Eljialy
    • International Journal of Computer Science & Network Security
    • /
    • 제23권12호
    • /
    • pp.187-193
    • /
    • 2023
  • Large software systems are being produced with a noticeably higher level of quality with component-based software engineering (CBSE), which places a strong emphasis on breaking down engineered systems into logical or functional components with clearly defined interfaces for inter-component communication. The component-based software engineering is applicable for the commercial products of open-source software. Software metrics play a major role in application development which improves the quantitative measurement of analyzing, scheduling, and reiterating the software module. This methodology will provide an improved result in the process, of better quality and higher usage of software development. The major concern is about the software complexity which is focused on the development and deployment of software. Software metrics will provide an accurate result of software quality, risk, reliability, functionality, and reusability of the component. The proposed metrics are used to assess many aspects of the process, including efficiency, reusability, product interaction, and process complexity. The details description of the various software quality metrics that may be found in the literature on software engineering. In this study, it is explored the advantages and disadvantages of the various software metrics. The topic of component-based software engineering is discussed in this paper along with metrics for software quality, object-oriented metrics, and improved performance.

Downregulation of the Expression of Steroidogenic Acute Regulatory Protein and Aromatase in Steroidogenic KGN Human Granulosa Cells after Exposure to Bisphenol A

  • Ji-Eun Park;Seung Gee Lee;Seung-Jin Lee;Wook-Joon Yu;Jong-Min Kim
    • 한국발생생물학회지:발생과생식
    • /
    • 제27권4호
    • /
    • pp.185-193
    • /
    • 2023
  • Although increasing evidence of cause-and-effect relationship between BPA exposure and female reproductive disorders have been suggested through many studies, the precise biochemical and molecular mechanism(s) by which BPA interferes with steroidogenesis in the ovarian cells still remain unclear. Therefore, the purpose of this study was to discover the steroidogenic biomarker(s) associated with BPA treatment in human granulosa cell line, KGN. In this study, our results obtained via the analysis of steroidogenesis-related protein expression in KGN cells using quantitative polymerase chain reaction (qPCR) and western blot analyses revealed that the expression levels of steroidogenic acute regulatory (StAR) and aromatase decreased considerably and gradually after BPA treatment in a dose-dependent manner under BPA treatment. Further, remarkable decreases in their expression levels at the cellular levels were also confirmed via immunocytochemistry, and subsequent StAR and aromatase mRNA expression levels showed profiles similar to those observed for their proteins, i.e., both StAR and aromatase mRNA expression levels were significantly decreased under BPA treatment at concentrations ≥0.1 μM. We observed that follicle stimulating hormone upregulated StAR and aromatase protein expression levels; however, this effect was suppressed in the presence of BPA. Regarding the steroidogenic effects of BPA on KGN cells, controversies remain regarding the ultimate outcomes. Nevertheless, we believe that the results here presented imply that KGN cells have a good cellular and steroidogenic machinery for evaluating endocrine disruption. Therefore, StAR and aromatase could be stable and sensitive biomarkers in KGN cells for the cellular screening of the potential risk posed by exogenous and environmental chemicals to female reproductive (endocrine) function.