• Title/Summary/Keyword: Quantitative Trait

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Identification of Quantitative Traits Loci (QTL) Affecting Growth Traits in Pigs

  • Kim, T.H.;Choi, B.H.;Lee, H.K;Park, H.S.;Lee, H.Y.;Yoon, D.H.;Lee, J.W.;Jeong, G.J.;Cheong, I.C.;Oh, S.J.;Han, J.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.11
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    • pp.1524-1528
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    • 2005
  • Molecular genetic markers were used to detect chromosomal regions which contain economically important traits such as growth, carcass, and meat quality traits in pigs. A three generation resource population was constructed from a cross between Korean native boars and Landrace sows. A total of 240 F2 animals from intercross of F1 was produced. Phenotypic data on 17 traits, birth weight, body weights at 3, 5, 12, and 30 weeks of age, teat number, carcass weight, backfat thickness, body fat, backbone number, muscle pH, meat color, drip loss, cooking loss, water holding capacity, shear force, and intramuscular fat content were collected for F2 animals. Animals including grandparents (F0), parents (F1), and offspring (F2) were genotyped for 80 microsatellite markers covering from chromosome 1 to 10. Least squares regression interval mapping was used for quantitative trait loci (QTL) identification. Significance thresholds were determined by permutation tests. A total of 10 QTL were detected at 5% chromosome-wide significance levels for growth traits on SSCs 2, 4, 5, 6, and 8.

Environmental Change Uncovers Differences in Polygenic Effect of Chromosomes from a Natural Population of Drosophila melanogaster

  • Jeung, Min-Gull;Thompson, James-N.Jr;Lee, Chung-Choo
    • Animal cells and systems
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    • v.1 no.4
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    • pp.609-617
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    • 1997
  • Polygenic variation of sternopleural bristle number was investigated at the whole chromosome level in a natural population of Drosophila melanogasfer. Fifty pairs of second and third chromosomes were analyzed at $25^\circ{C}$. Since environmental factors such as temperature influence polygenic expression of quantitative traits, whole chromosomal effects of 28 pairs from the larger original sample were measured under cycling temperature, a $10-30\circ{C}$ cycle in 24 hours, to reveal any polygenic alleles whose effects might be masked under the constant temperature. While third chromosomes typically showed a larger contribution to polygenic variation in both environments, second chromosomes showed greater sensitivity to environmental changes. Cluster analyses of second and third chromosomes produced a limited number of clusters. Such a small number of cluster's implies that there may be a small number of genes, or quantitative trait loci (QTLs), having large effects on phenotypic variation. The genetic structure assessed under constant temperature, however, did not show any correlation with the structure under cycling temperature. The discrepancy could be caused by independent response of each polygenic allele to temperature changes. Thus, polygenic structure in natural populations should be thought of as a temporally changing profile of interactions between gene and ever-changing environment.

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Research trends of parentification in Korea(from 2003 to 2015) (자녀의 부모화(parentification)에 관한 국내연구동향 분석)

  • Seok, Mijeong
    • Journal of Family Relations
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    • v.21 no.2
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    • pp.53-75
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    • 2016
  • Objectives: The purpose of the present study is to analysis the trends of and issues in research about parentification in Korea up to date, and to propose directions for further studies. Methods: For this purpose, eighty one theses and articles about parentification, published from 2003 to 2015 were categorized according to research subjects, research objects, research methods, statistical analysis methods, and related variables with the parentification. Results: Consequently, first, the number of articles published has been gradually increased. Second, the main research subjects were the characteristics and trait of parentification, an interpersonal relationship and family. Third, the common research objects were undergraduate student/graduate student and youth(middle/high school students). Fourth, the quantitative research methods have been used mainly. FRS-A(Filial Responsibility Scale-Adult) and FRS-Y(Filial Responsibility Scale-Youth) have been used most. A high frequency related variables with parentification were the affectiveness-related variables, in particularly, the shame proneness is the highest correlation variables. Conclusions: Based on the findings in this study, it is suggested that the research objects should be more varied and the Korean parentification measurements need to be developed in the near future.

Islamic Legal Reasoning for the Justification of Tax Evasion: The Case of Indonesia

  • HIDAYAT, Nurul;SHARKEY, Nolan
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.8
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    • pp.475-486
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    • 2021
  • Religiosity is often perceived as a trait that can effectively suppress attitudes and behavior that lead to people evading taxes. However, this study finds that Islamic religiosity has a complicated relationship with tax evasion. This study employs a mixed-method, which involves collecting, analyzing, and integrating quantitative and qualitative research, and this integration provides a better understanding of the research problem. Qualitative analyses of the sermons of prominent Islamic clerics speaking on taxes on YouTube channels revealed different views. The textualists/conservative clerics viewed taxes are prohibited based on the fact of Islamic history and tax prohibition stated in a hadith. Furthermore, tax compliance is determined solely by the threat of punishment from the government. On the other hand, the moderate preachers seem to be more flexible in response to tax issues. They involve the framework of contextual and analogical-historical practice. Quantitative analyses from the survey found that Islamic religiosity is not directly correlated with tax evasion. However, the sentiment of Islamic law adoption by the state has significantly mediated the correlation between them. In addition, respondents who affiliate with moderate Islamic organizations tend to have less justification of tax evasion than those who affiliate with conservative organizations or movements.

Analysis of effects of burning in grasslands with quantifying succession stages by life-history traits in Kirigamine, central Japan

  • Kato, Jun;Kawakami, Mihoko
    • Journal of Ecology and Environment
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    • v.36 no.1
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    • pp.101-112
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    • 2013
  • To quantitatively analyze the effects of burning, we conducted a vegetation survey in the grasslands in Kirigamine, central Japan. We classified each species into stages of succession based on the life-history traits of the species and defined the score of the species in each stand based on the classification. We weighted the scores with a v-value, the product of coverage and height in the quadrat, and summed them to calculate the index of dynamic status. With these indices, we were able to quantitatively compare the stands in the study area and discern minute differences between the stands with different lengths of restoration periods since the disturbance of burning. These indices correlated with the v-value of trees, suggesting that the disturbance of burning seemed to affect the trees in the stand. We then calculated the growth of the tree species Pinus densiflora to evaluate its contribution to the index of dynamic status.

Bootstrap Analysis and Major DNA Markers of BM4311 Microsatellite Locus in Hanwoo Chromosome 6

  • Yeo, Jung-Sou;Kim, Jae-Woo;Shin, Hyo-Sub;Lee, Jea-Young
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.8
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    • pp.1033-1038
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    • 2004
  • LOD scores related to marbling scores and permutation test have been applied for the purpose detecting quantitative trait loci (QTL) and we selected a considerable major locus BM4311. K-means clustering, for the major DNA marker mining of BM4311 microsatellite loci in Hanwoo chromosome 6, has been tried and five traits are divided by three cluster groups. Then, the three cluster groups are classified according to six DNA markers. Finally, bootstrap test method to calculate confidence intervals, using resampling method, has been adapted in order to find major DNA markers. It could be concluded that the major markers of BM4311 locus in Hanwoo chromosome 6 were DNA marker 100 and 95 bp.

한우 6번 염색체의 Bootstrap기법을 이용한 우수 DNA 탐색

  • Lee, Je-Yeong;Yeo, Jeong-Su;Kim, Jae-Woo;Lee, Yong-Won;Kim, Mun-Jeong
    • 한국데이터정보과학회:학술대회논문집
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    • 2003.05a
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    • pp.41-47
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    • 2003
  • 한우 6번 염색체 유전자 지도에서 한우의 질을 높이기 위한 QTL(quantitative trait loci)분석을 실시하여 선별된 Loci 값을 Permutation Test를 이용하여 계산하였다. 한편, 경제적으로 주요한 한우의 특성부위(질적부위와 육량등)에 따른, 우수 경제형질 DNA marker를 K-평균 군집법을 실시 파악하였다. 이들 QTL과 K-평균법에 의해 한우의 염색체 6번, ILST035의 주요 경제 형질별 DNA marker들을 선별하여, Bootstrap BCa방법을 이용하여 각 DNA marker들의 신뢰구간을 구했다.

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THE EFFECTS OF POPULATION SIZE AND DOMINANCE OF QUANTITATIVE TRAIT LOCI (QTL) ON THE DETECTION OF LINKAGE BETWEEN MARKERS AND QTL FOR LIVESTOCK

  • Jeon, G.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.8 no.6
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    • pp.651-655
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    • 1995
  • A simulation study on detection of linkage between genetic markers and QTL in backcross design was conducted. The effects of various sample sizes and the degree of QTL dominance on detention of linkage were examined by using a simple regression analysis. The results indicated that as sample size increased, the standard error of the estimated slope became smaller. When the dominance effect of QTL was complete, the estimated slope tended to be negative but was statistically not significant at all with type I error of greater than 50%. With complete linkage between genetic Marker and QTL, the estimated intercept value was smallest but the estimated slope was largest as expected. In most cases with various degree of dominance and sample sizes, when the actual recombination rate became larger, greater values were obtained for the slope except in the case of complete dominance of QTL.

한우의 Chromosome 6에서 BM4311의 중요 DNA Mining

  • Kim, Mun-Jeong;Lee, Je-Yeong;Yeo, Jeong-Su;Lee, Yong-Won;Jo, Yong-Ju
    • Proceedings of the Korean Statistical Society Conference
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    • 2003.05a
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    • pp.305-311
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    • 2003
  • K-Means 모델을 이용하여 한우 유전자 6번의 BM4311의 중요 DNA marker을 찾기위해 여러 가지로 시도해 왔다. 이번 논문에선 QTL(Quantitative Trait Loci)과 data mining modeling를 이용하여 BM4311에서 중요 DNA marker를 찾아 보도록 하겠다.

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