• Korean Journal of Construction Engineering and Management
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• v.6 no.4 s.26
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• pp.80-90
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• 2005

Activity durations retain probabilistic and stochastic natures due to diverse factors causing the delay or acceleration of activity completion. These natures make the final project duration to be a random variable. These factors are the major source of financial risk. Extending the Stochastic Project Scheduling Simulation system (SPSS) developed in previous research; this research presents a method to estimate how the final project duration behaves when activity durations change randomly. The final project cost is estimated by considering the fluctuation of indirect cost, which occurs due to the delay or acceleration of activity completion, along with direct cost assigned to an activity. The final project cost is estimated by considering how indirect cost behaves when activity duration change. The method quantifies the amount of contingency to cover the expected delay of project delivery. It is based on the quantitative analysis to obtain the descriptive statistics from the simulation outputs (final project durations). Existing deterministic scheduling method apply an arbitrary figures to the amount of delay contingency with uncertainty. However, the stochastic method developed in this research allows computing the amount of delay contingency with certainty and certain degree of confidence. An example project is used to illustrate the quantitative analysis method using simulation. When the statistical location and shape of probability distribution functions defining activity durations change, how the final project duration and cost behave are ascertained using automated sensitivity analysis method

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.314-317
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• 2002

The purpose of this study was to evaluate the clinical application of Patlak tool on GE PET workstation for quantitative analysis of dynamic PET images in cardiac patients. Three patients including coronary artery disease (CAD), myocardial infarction (MI), and angina were studied. All subjects underwent dynamic cardiac PET scan using a GE Advance scanner. After 10 min transmission scan for attenuation correction using two rotating $\^$68/Ge rod sources, three patients with cardiac disease were performed dynamic cardiac PET scan after the administration of approximately 370 MBq of FDG. The dynamic scan consisted of 36 frames with variable frame length (12${\times}$10s, 6${\times}$20s, 6${\times}$60s, 12${\times}$300s) for a total time of 70 min. Blood samples were obtained to determine the plasma substrate concentration. Region of interest of circular and rectangular shape to acquire input functions and tissue data were placed on left ventricle and myocardium. A value of 0.67 was used for lumped constant. Mean plasma substrate concentrations for three patients were 100 mg/dl (CAD), 100 mg/dl (MI), 132 mg/dl (angina), respectively. Regional MMRGlc values (mean${\pm}$SD) at lateral myocardium area for CAD, MI, and angina were 8.43${\pm}$0.24, 4.08${\pm}$0.16, and 6.15${\pm}$0.23 mg/min/100ml, respectively. Patlak tool on GE PET workstation appeared to be useful for quantitative analysis of dynamic PET images in cardiac patients, although further studies may be required for absolute quantitation.

• International Journal of Highway Engineering
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• v.20 no.1
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• pp.35-45
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• 2018

PURPOSES : This study examines the performance changes of road networks according to the strength of a disaster, and proposes a method for estimating the quantitative resilience according to the road-network performance changes and damage scale. This study also selected high-influence road sections, according to disasters targeting the road network, and aimed to analyze their hazard resilience from the network aspect through a scenario analysis of the damage recovery after a disaster occurred. METHODS : The analysis was conducted targeting Sejong City in South Korea. The disaster situation was set up using the TransCAD and VISSIM traffic-simulation software. First, the study analyzed how road-network damage changed the user's travel pattern and travel time, and how it affected the complete network. Secondly, the functional aspects of the road networks were analyzed using quantitative resilience. Finally, based on the road-network performance change and resilience, priority-management road sections were selected. RESULTS : According to the analysis results, when a road section has relatively low connectivity and low traffic, its effect on the complete network is insignificant. Moreover, certain road sections with relatively high importance can suffer a performance loss from major damage, for e.g., sections where bridges, tunnels, or underground roads are located, roads where no bypasses exist or they exist far from the concerned road, including entrances and exits to suburban areas. Relatively important roads have the potential to significantly degrade the network performance when a disaster occurs. Because of the high risk of delays or isolation, they may lead to secondary damage. Thus, it is necessary to manage the roads to maintain their performance. CONCLUSIONS : As a baseline study to establish measures for traffic prevention, this study considered the performance of a road network, selected high-influence road sections within the road network, and analyzed the quantitative resilience of the road network according to scenarios. The road users' passage-pattern changes were analyzed through simulation analysis using the User Equilibrium model. Based on the analysis results, the resilience in each scenario was examined and compared. Sections where a road's performance loss had a significant influence on the network were targeted. The study results were judged to become basic research data for establishing response plans to restore the original functions and performance of the destroyed and damage road networks, and for selecting maintenance priorities.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.4
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• pp.430-440
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• 2021

The purpose of this study was to analyze the degree of depression, cognitive function, communication ability, and the quantitative electroencephalogram (EEG) in elderly individuals with hearing loss and to investigate their inter-relationship. Hearing-impaired elderly participants, aged 60 years or older (37 men and 26 women) who visited the S Hearing Rehabilitation Center in Y City from June 20, 2020, to September 3, 2020, participated voluntarily after a recruitment announcement.The participants' overall characteristics, depression, and cognitive functions were evaluated with a structured questionnaire. The Word Recognition Score (WRS) was evaluated with an audiometer using the Korean Standard Monosyllabic Word Lists for Adults (KS-MWL-A). The quantitative EEG was measured with dry electrodes using a 2-channel EEG on the frontal lobes Fp1 and Fp2. The results are summarized as follows: Communication ability showed a positive correlation with the left-right symmetry of the frontal lobes (**p<.01) and a negative correlation with right-brain mental distraction and stress (*p<.05). In the difference WRS test for each group, the left-right symmetry of the frontal lobes (**p<.01) showed the greatest correlation with communication ability. Our results suggest that the left-right symmetry of the frontal lobes can be a biomarker indicative of the communication ability of older people with hearing impairments.

• Korean Institute of Interior Design Journal
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• v.20 no.6
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• pp.36-43
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• 2011

The study presupposes that, ever since its modernization, the Korean local government buildings have undergone an evolutionary process of their spatial organizations and the process can be analyzed in terms of increased publicness of architectural space. For the purpose, fifteen examples of local government buildings in Korea are selected and analyzed in terms of their plans converted into spatial diagrams measuring accessibility depth. Within these analytical diagrams, some quantitative measures such as permeability and visual connection, and the number of decision making points that visitors face on the way to their targets. The study analyzes these analytic measures of selected samples which are categorized into three chronological groups in order to search any evolutionary tendency of spatial transformation. The analysis shows that the accessibility of public functions and presumably the publicness of the spatial organization of local government buildings has been increased. The results of the study implies that, to acquire architectural publicness in government buildings, not only the insertion of public programs but also the organization of open spatial structure is significant.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.633-636
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• 2012

Purpose: PRIL (proliferation-inducing ligand) is a newly identified member of the tumor necrosis factor (TNF) family and modulates death ligand-induced apoptosis. Here, we investigated the effect of PRIL on cellular characteristics relating to tumor progression in human gastric cancer. Method: Recombinant lentivirus containing PRIL siRNA was constructed and then infected MGC803 and SGC7901 gastric cancer cells. MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] colony formation and cell cycle analysis were used to study the effect of PRIL knockdown on gastric cancer cell proliferation. Results: PRIL expression in lentivirus infected cells was significantly reduced as evidenced by quantitative real-time PCR. Cell viability and colony formation of MGC803 and SGC7901 cells were significantly hampered in PRIL knock-down cells. Moreover, the cell cycle was arrested at G2/M phase, elucidating the mechanism underlying the inhibitory effect of siRNA on cell proliferation. Conclusions: Our study indicated that PRIL functions in promoting cell growth, and lentivirus-mediated PRIL gene knockdown might be a promising strategy in the treatment of gastric cancer.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.6
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• pp.2963-2978
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• 2017

The Top-K query is currently played a key role in a wide range of road network, decision making and quantitative financial research. In this paper, a Top-K recommendation algorithm is proposed to solve the cold-start problem and a tag generating method is put forward to enhance the semantic understanding of the OLAP session. In addition, a recommendation system for OLAP sessions called "OLAP4R" is designed using collaborative filtering technique aiming at guiding the user to find the ultimate goals by interactive queries. OLAP4R utilizes a mixed system architecture consisting of multiple functional modules, which have a high extension capability to support additional functions. This system structure allows the user to configure multi-dimensional hierarchies and desirable measures to analyze the specific requirement and gives recommendations with forthright responses. Experimental results show that our method has raised 20% recall of the recommendations comparing the traditional collaborative filtering and a visualization tag of the recommended sessions will be provided with modified changes for the user to understand.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.2
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• pp.31-39
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• 1998

In this paper, we have presented a quantitative performance effect of CCP(Call Control Processor) when SAAL(Signalling ATM Adaptation Layer) function is distributed from CCP to SIMs(Subscriber Interface Modules) in an ATM switching system with distributed architecutre. For the performance analysis, SLAM II simulation language is used and subscriber signalling messageand inter-processor communication messages according to Q.2931 based local call processing procedure are taken into consideration in the proposed queuing network model. The results of simulation are compared with in case of processing SAAL function on CCP. It is observed that the processing utilization of CCP reach 24,000 BHCA and 25,700 BHCAwhen SAAL function load amounts to 10% and 20% of the processing time of the total message, respectively. These values shows that the processing utilization of CCP is alleviated about 7% in comparison with 2,000 BHCA in case that SAAL function is carried out on CCP. Consquently, it is shown that we have to consider seriously how to distribute the functions concerning call processing in a large cale ATM switching system architecture accomodating a number of SIMs.

• Journal of the Korean Operations Research and Management Science Society
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• v.25 no.3
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• pp.109-124
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• 2000

For rational human value judgement and evaluation, provision of clear evaluation data, objective value judgement criteria, and properly generalized methods are required. For instance, this is true for software quality evaluation, and the measure of software quality and the weighting method of evaluation target directly affect final decisions. However it is not easy to find a generalized method for the software quality evaluation or product selection, because of its complex characteristics. In this paper, we apply the qualitative preference method based on quantitative belief functions to find a general weighing method for the software quality evaluation. In particular, the qualitative preference method, in which the differentiated preference expression is possible, is conceptually expanded for general applications in future. For this purpose, we hierarchically differentiate the strong preference relation from the weak preference relation, and show an example of quantification of software quality evaluation on different applications, by comparing the qualitative preference method with AHP. We believe that the application domain of this method is not limited to the software quality evaluation and it is very useful to apply this results to other SE areas, e.g., metric selection with different views and riority determination of practices to be assessed in the SPICE.

• Journal of Microbiology and Biotechnology
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• v.13 no.6
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• pp.872-880
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• 2003

Three vectors, pSG1, 2, and 3, which facilitate in vivo expression technology (IVET) in Gram-negative bacteria, were developed. Vectors pSG1and 2 are derivatives of ColE1, and pSG3 is a derivative of an R6K replicon. These vectors contain oriT sites that allow mobilization when the RK2 Tra functions are provided in trans. These vectors contain promoterless lacZ (pl-lacZ) and promoterless aph (pl-aph) transcriptionally fused together, which allow qualitative and quantitative measurements of the expression of genes in the genome of bacterial cells. pSG1 and 3 contain gentamicin-resistance genes, and pSG2 carries a streptomycin-/spectinomycin-resistance gene, allowing for selection of recombinants generated by a single crossover between a library fragment cloned into a pSG vector and the identical region in the genome of a bacterial species from which the library fragment originated. These vectors were successfully applied to the generation of random fusions at high rates in the genomes of four representative Gram-negative bacteria. In addition, the expression level of ${\beta}-galactosidase$ and the degree of resistance to kanamycin in cells with fusions generated by these vectors were found to be linearly correlated, proving that these vectors can be used for IVET.