• Title/Summary/Keyword: Quantitative Effect Evaluation

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Comprehensive Evaluation of the Anti-Helicobacter pylori Activity of Scutellariae Radix

  • Lee, Ba Wool;Park, Il-Ho;Yim, Dongsool;Choi, Sung Sook
    • Natural Product Sciences
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    • 제23권1호
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    • pp.46-52
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    • 2017
  • The aim of this study was to evaluate the anti-Helicobacter pylori activity of fractions and major aglycon compounds (baicalein, chrysin, oroxylin A, wogonin) of Scutellariae Radix. Minimum inhibitory concentration (MIC) measurement, DPPH radical-scavenging assay, DNA protection assay, and urease inhibition analysis were performed. The ethyl acetate (EtOAc) fraction showed the potent anti-Helicobacter activity, and therefore, compounds in the EtOAc fraction were subjected to further assay. The MICs of chrysin, oroxylin A, and wogonin against Helicobacter pylori 26695 were 6.25, 12.5 and $25{\mu}g/mL$, respectively. Baicalein exhibited the most effective DPPH radical-scavenging activity. DNA protection using Fenton reaction, chrysin, oroxylin A, and wogonin showed effective DNA protective effect. This result was also confirmed by quantitative real-time polymerase chain reaction (qRT-PCR). Regarding Jack bean urease (0.5 mg/mL, 50 unit/mg) inhibition, 20 mM ofbaicalein and chrysin inhibited urease activity by 88.2% and 72.5%, respectively.

연료 분사 특성이 가솔린 엔진 HC 배출에 미치는 영향 (Effects of Port Fuel Injection Characteristics upon HC Emission in SI Engines)

  • 우영민;배충식;이동원
    • 한국자동차공학회논문집
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    • 제11권2호
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    • pp.8-15
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    • 2003
  • During cold operation, fuel injection in the intake port directly contributes to the unburned hydrocarbon formation in spark ignition engines. The relationship between injection parameters and HC emission behavior was investigated through a series of experiments. Spray behavior of port fuel injectors was characterized through a quantitative evaluation of mass concentration of liquid fuel by a patternator and PDA(Phase-Doppler. Anemometer). A 6-hole injector was found to produce finer spray than single hole injector. Using a purpose-built wall, the wetted fuel was measured, which was mostly affected by wall temperature. HC emissions were measured in a production engine varying coolant temperature$(20~80^{\circ}C)$, also with respect to the different types of injectors. In the 6-hole injector application, the engine produced less HC emission in low coolant temperature region. Though it produces much more amount of wetting fuel, it has the advantages of finer atomization quality. In high coolant temperature region, there was little effect by different types of injectors. The control schemes to reduce HC emissions during cold start could be suggested from the findings that the amount of fuel supply and HC emission could be reduced by utilizing fine spray and high intake wall temperature.

건강코칭프로그램이 빈곤계층 고혈압대상자의 자기효능감, 건강행위실천 및 삶의 질에 미치는 효과 (The Effect of Health Coaching Programs on Self-Efficacy, Health Behaviors, and Quality of Life in Hypertensive People Living in Poverty)

  • 엄선옥;이인숙
    • 대한간호학회지
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    • 제47권3호
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    • pp.380-391
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    • 2017
  • Purpose: This study was designed to determine the effects of health coaching and mediating variables on quantitative aspect of health in low-income hypertensive people. Methods: The experimental group for the current study consisted of 21 clients who received health coaching services, and the control group consisted of 22 clients who received home-visiting nursing services. Two groups received health coaching or home-visiting nursing services once a week for 8 weeks. The evaluation variables were self-efficacy, nutrition management, health behaviors, self-rated health, and quality of life. Results: The results revealed that the level of nutrition management was significantly higher in the experimental group than the control group (F=10.33, p=.005). Conclusion: These results confirm that health coaching is a useful strategy that encourages clients to continuously maintain their own health behaviors. Thus, the findings of the current study provide useful data for establishing measures for the health management of those afflicted with chronic disease, such as hypertension. Furthermore, health coaching may be developed into useful intervention strategies for dealing with chronic diseases and improving home-visiting nursing.

2행정 디젤기관의 소기 효율 평가에 관한 연구 (A Study on the Evaluation of Scavenging Efficiency in a Two-Stroke Diesel Engine.)

  • 조규백;강건용;이진욱;정용일
    • 연구논문집
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    • 통권28호
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    • pp.49-58
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    • 1998
  • 포핏밸브형 2행정 기관의 소기 시스템 형상 변화에 따른 소기유동 및 소기효율의 개선 효과를 해석하기 위해, 각 흡기포트 형상별 소기 유동 가시화와 소기효율 정량화 연구를 수행하고자 한다. 소기시스템의 형상은 기계연구원에서 독자 개발한 RSSV(Rotatable Shrouded Scavenging Valve)의 슈라우드 각도를 변화시켰으며, 소기 효율 정량화를 위해 정상상태하에서 등유와 착색된 물을 사용한 single-cycle method. 동적모사장치(dynamic simulatior)에서 $CO_2$$O_2$가스를 사용한 가스추출법(gas sampling method)을 적용하였으며 실제 기관에서의 소기 효율을 측정하기 위해 압력 선도를 해석하였다. 위 실험들의 결과로부터 $90^circ$슈라우드 밸브가 가장 높은 효율을 가지는 것으로 판명되었으며, 특히 이들 실험방법들은 2행정 엔진 개발에 있어 시간과 비용을 절감하는데 아주 유용한 기법임을 알 수 있었다.

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냉장고 가스켓 형상 변화에 따른 냉장고 열손실 저감 효과 (The Effect of Gasket Shape on Heat Loss Reduction in a Refrigeration)

  • 하지수;정광수;김태권;김경호;김석로
    • 설비공학논문집
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    • 제21권5호
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    • pp.305-310
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    • 2009
  • The amount of heat loss of a refrigerator through the gasket is nearly 30% of total refrigerator heat loss. In this paper, quantitative evaluation analysis of heat loss through gasket is established with numerical heat transfer analysis. Extending the gasket shape to protect the heat loss from the gasket, power consumption is measured by using real refrigerator in a temperature and humidity chamber and suggest the gasket shape to reduce the heat loss. From the present result of the numerical simulation of heat transfer and experiment with varying gasket shape, we are able to reduce the heat loss about 20-40% by using extended gasket and the power consumption can be reduced about 5%.

Electrochemical Evaluation of Si-Incorporated Diamond-Like Carbon (DLC) Coatings Deposited on STS 316L and Ti Alloy for Biomedical Applications

  • Kim, Jung-Gu;Lee, Kwang-Ryeol;Kim, Young-Sik;Hwang, Woon-Suk
    • Corrosion Science and Technology
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    • 제6권1호
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    • pp.18-23
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    • 2007
  • DLC coatings have been deposited onto substrate of STS 316L and Ti alloy using r.f. PACVD (plasma-assisted chemical vapor deposition) with a mixture of $C_{6}H_{6}$ and $SiH_{4}$ as the process gases. Corrosion performance of DLC coatings was investigated by electrochemical techniques (potentiodynamic polarization test and electrochemical impedance spectroscopy) and surface analysis (scanning electron microscopy). The electrolyte used in this test was a 0.89% NaCl solution of pH 7.4 at temperature $37^{\circ}C$. The porosity and protective efficiency of DLC coatings were obtained using potentiodynamic polarization test. Moreover, the delamination area and volume fraction of water uptake of DLC coatings as a function of immersion time were calculated using electrochemical impedance spectroscopy. This study provides the reliable and quantitative data for assessment of the effect of substrate on corrosion performance of Si-DLC coatings. The results showed that Si-DLC coating on Ti alloy could improve corrosion resistance more than that on STS 316L in the simulated body fluid environment. This could be attributed to the formation of a dense and low-porosity coating, which impedes the penetration of water and ions.

The Chinese Performance-based Code for Fire-resistance of Steel Structures

  • Li, Guo-Qiang;Zhang, Chao
    • 국제초고층학회논문집
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    • 제2권2호
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    • pp.123-130
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    • 2013
  • In the past two decades, researchers from different countries have conducted series of experimental and theoretical studies to investigate the behaviour of structures in fire. Many new insights, data and calculation methods have been reported, which form the basis for modern interdisciplinary structural fire engineering. Some of those methods are now adopted in quantitative performance-based codes and have been migrated into practice. Mainly based on the achievements in structural fire research at China, the Chinese national code for fire safety of steel structures in buildings has been drafted and approved, and will be released in this year. The code is developed to prevent steel structures subjected to fire from collapsing, ensure safe evacuation of building occupants, and reduce the cost for repairing the damages of the structure caused by fire. This paper presents the main contents of the code, which includes the fire duration requirements of structural components, fundamental requirements on fire safety design of steel components, temperature increasing of atmosphere and structural components in fire, loading effect and capacity of various components in fire, and procedure for fire-resistant check and design of steel components. The analytical approaches employed in the code and their validation works are also presented.

Post-peak behavior and flexural ductility of doubly reinforced normal- and high-strength concrete beams

  • Pam, H.J.;Kwan, A.K.H.;Ho, J.C.M.
    • Structural Engineering and Mechanics
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    • 제12권5호
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    • pp.459-474
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    • 2001
  • The complete moment-curvature curves of doubly reinforced concrete beams made of normal- or high-strength concrete have been evaluated using a newly developed analytical method that takes into account the stress-path dependence of the constitutive properties of the materials. From the moment-curvature curves and the strain distribution results obtained, the post-peak behavior and flexural ductility of doubly reinforced normal- and high-strength concrete beam sections are studied. It is found that the major factors affecting the flexural ductility of reinforced concrete beam sections are the tension steel ratio, compression steel ratio and concrete grade. Generally, the flexural ductility decreases as the amount of tension reinforcement increases, but increases as the amount of compression reinforcement increases. However, the effect of the concrete grade on flexural ductility is fairly complicated, as will be explained in the paper. Quantitative analysis of such effects has been carried out and a formula for direct evaluation of the flexural ductility of doubly reinforced concrete sections developed. The formula should be useful for the ductility design of doubly reinforced normal- and high-strength concrete beams.

Costunolide와 Dehydrocostuslactone을 이용한 목향의 함량분석 (Quantitative Analysis of Aucklandia Lappa Using Costunolide and Dehydrocostuslactone)

  • 엄민례;원진배;윤보라;이지우;마충제
    • 생약학회지
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    • 제44권3호
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    • pp.235-241
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    • 2013
  • Aucklandia lappa Decne (Compositae) has been used for treatment of abdominal pain, vomiting, diarrhea, chronic inflammation, and antibacterial effect. The quality of these herbs has been affected by many factors such as collection time, place, temperature, cultivation environment and manufacturing process. We used costunolide and dehydrocostuslactone as marker compounds for quality evaluation of rhizome of Aucklandia lappa. 66 samples of Aucklandia lappa were collected from those habitats in Korea and China. The developed HPLC-DAD method was applied to investigate for quality control of Aucklandia lappa samples. The average contents of the costunolide and dehydrocostuslactone were 2.3895% and 0.9258%, respectively. The principal component analysis (PCA) exhibited that classification of Aucklandia lappa according to origin not separated. Results of this study may be satisfactory applied to determination of content criteria of Aucklandia lappa.

성형공법에 따른 초고강도 모자형 박판부품 형상정밀도 평가 (Quantitative Evaluation of Shape Accuracy in a Hat-type Product with UHSS according to the Forming Procedure)

  • 최병현;김세호;김흥규
    • 한국정밀공학회지
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    • 제30권10호
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    • pp.1111-1117
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    • 2013
  • In this paper, the shape accuracy of the stamped hat-type product is quantified and analyzed with ultra high strength steel (UHSS) sheets. The shape of the hat-type product is designed in order to simplify the geometry of the side sill and the stamping methodology is proposed in order to verify the effect of the stamping procedure on the springback amount. Experiments and finite element analyses are conducted with four kinds of the forming sequences. The springback amounts are measured and compared according to the forming procedure with the embossing shape. Experimental result in company with analysis one illustrate that the springback amount is reduced with embossing in the padding operation. They also fully demonstrates the proposed forming procedure and the analysis method can be effectively applied to the process design for producing parts with ultra high strength steel.