• 한국임상약학회지
• /
• 제24권4호
• /
• pp.255-264
• /
• 2014

Objective: The aims of this study are to investigate the total volume of prescribed medicines against Alzheimer's disease (AD) and the trends of usage by analyzing the claims-data from the Korea National Health Insurance Service. Method: The demographic and claims-data were included the major AD treating medicines such as donepezil, galantamine, rivastigmine and memantine, and analyzed during the period of 2010~2012. The assessing criteria were gender, age, habitation, types of medical institution, code of ingredients, outcomes of treatment, volume and amount of claims, and the numbers of patients with dementias. After trimming the data, it were analyzed by the market size, demographic traits, characteristics of medical service, characteristics of each anti-AD medicine, etc. Results: Among the chosen 4 medicines, donepezil had the top prescription volumes. Most prevalent prescribing preparations of donepezil were conventional types. However, among the non-conventional types, oro-dispersible formulation is the fast increasing one in both volume and growth rate. This specialized preparations to improve both toleration and adherence, tend to being prescribed generally at the tertiary medical institutions. While the younger patients with mild-to-moderate AD mostly treated by expensive medicines in resident at the tertiary hospitals, the rest older patients with severe AD have been treated non-expensive one at long-term care facilities. Conclusion: AD is a chronic illness therefore, long-term use of therapeutic medications are highly important. If an anti-AD treatment was applied steadily in the earlier stages, it would be achieved not only improving the quality of life of patient but also reducing the expenses in the medical and nursing cares. As the socioeconomical impacts of AD is expanding, healthcare professionals need to aware the importance of pharmacotherapy and to improve sociopolitical fundamentals.

• KIEAE Journal
• /
• 제16권4호
• /
• pp.41-46
• /
• 2016

Purpose: This is a study on the planning of temporary housing for post application of Mega Sports facilities. The subject of the study is 2018 Pyeongchang Winter Olympics, which is to suggest building an alternative temporary housing using shipping containers(high cube), which solve the lack of accommodations and recycle temporary housing after Olympics, save money and be eco-friendly in Olympics. Method: This study includes this ; research on the a fact-finding survey about Mega sports facilities post application and demand survey on 2018 Pyeongchang Winter Olympics accomodations and an analysis about temporary housing plan. Furthermore we decided temporary housing building plan by analyzing residents' needs and traits of the housing etc. Through this, we made a schematic design for household units. Result: As a result, this study is a plan of making space, forms, and structure. The planned size is $38.4m^2$(L:12m, W:3.2m) except balcony, and indoor height is 2.5m. The space consists of entrance, bathroom, bedroom and living room with folding furniture system. Also there's a detailed floor plan of the ceiling, wall, and floor we drew up. The ceiling and wall consist of dampproof film, noncombustible board, fire proof urethane form, and color-designed sheet. The floor is composed of floor tile, cement mortar, light concrete(with heat coil), insulation, and dampproof film. Additionally, this study is a plan of interior dry wall with detail using modular construction method for work efficiency and quality improvement.

• 환경영향평가
• /
• 제21권1호
• /
• pp.81-91
• /
• 2012

In this study, it is grasped the status of nutrients through an investigation of release characteristics and physicochemical properties of sediments on reservoir. And then the effect of sediments is evaluated on the water quality in reservoir. In the results of physicochemical analysis, the pollution level of midstream is the highest, which shows the traits that the water is more deeper and takes place a deposition consistently. Then, the pollution level of upstream is higher than downstream's because inflow has influence on the upstream directly. The downstream is located near tidal gate so that the soil particles can be moved easily and are difficult to be deposited due to the distribution of seawater by control of tidal gate. Therefore, the downstream is showed the lowest pollution level than the others. Also, the concentration of SOD(Sediment Oxygen Demand) in the upstream which is influenced on the effect of inflow is highest than the others. When it analyzes under anaerobic and aerobic condition to understand the release characteristic of sediment, it shows that the release rate is low or negative under the aerobic condition. Whereas the release rate is usually positive under the unaerobic condition relatively. According to these results, it is necessary to maintain the proper environmental factors of water body for decreasing the release rate of sediment. Because the release rate is changeable under the different condition of water body. Therefore, proper strategies are required for increasing the self-purification of water as well as keeping the aerobic condition of sediment and managing a sediment layer directly to control the inner-pollution by the sediment of reservoir.

• 한국가금학회지
• /
• 제48권2호
• /
• pp.51-58
• /
• 2021

지방산 조성은 고기의 풍미에 영향력 있는 중요한 경제 형질 중 하나이며, 다양한 유전자들의 효과가 알려져 있다. 본 연구는 한국 재래닭의 지방산 조성에 유의적인 영향을 미치는 것으로 조사된 6개의 후보 유전자들(DEGS1, ELOVL6, FABP3, FABP4, FASN, SCD)의 51개 SNP 조합에 대한 추가적인 분석결과로, 선행연구를 통하여 확인된 SNP 조합들이 가지는 상위성 효과에 대하여 조사하였다. 본 연구를 통하여 매우 다양한 유형의 SNP 조합들이 한국 재래닭의 지방산 조성에 영향을 미치는 것으로 확인되었으며, 추후에 지방산 조성과 같은 다유전자성 형질들을 실제 육종 프로그램에 활용하기 위해서는 이러한 분석이 이루어져야 될 것으로 생각된다. 본 연구 결과는 한국 재래닭의 육질, 특히 지방산 조성의 개선을 위한 유전학적인 정보를 제공할 수 있을 것으로 생각된다.

• 한국육종학회지
• /
• 제40권1호
• /
• pp.72-75
• /
• 2008

'그린뷰티' 품종은 경기도농업기술원에서 2005년도에 육성한 절화용 장미 신품종이다 이 품종은 2000년도에 화색이 분홍색이며 화형이 우수한 스탠다드 장미 'Qvarna' 품종을 모본으로 하고 향기가 있는 노랑색 스탠다드 장미 'Sky Line' 품종을 부본으로 하여 교배를 하였다. 2000년에 실생을 양성하여 화색과 화형이 우수한 13계통을 예비선발 하였으며 2001~2005년에 1,2,3차 특성검정과 품평회 결과 절화특성이 우수한 KR99-62-1(Gyeonggi R1-8)계통을 최종 선발하였다. 화색은 연한오렌지색과 녹색의 복색이며 중형 크기의 스탠다드 형태로 개화하고 화형은 반고심형이며 꽃잎수는 61.2매이고 향기 정도는 약한 편이다. 년간 절화수량은 178본/$m^2$이고 절화장은 64.6cm이며 줄기직경은 6.0mm이고 엽수는 13.6매이며 절화중은 28.6g이고 절화수명은 14일이다.

• 한국육종학회지
• /
• 제40권1호
• /
• pp.76-79
• /
• 2008

'퓨어하트' 품종은 경기도농업기술원에서 2002년도에 육성한 절화용 장미 신품종이다. 이 품종은 1998년도에 화색이 분홍색이며 화형이 우수한 스탠다드 장미 'Saphir' 품종을 모본으로 하고 향기가 있는 백색 스탠다드 장미 'Crystal Line' 품종을 부본으로 하여 교배를 하였다. 1998년에 실생을 양성하여 화색과 화형이 우수한 25계통을 예비선발 하였으며 2000~2002년에 1, 2, 3차 특성검정과 품평회 결과 절화특성이 우수한 KR98-12-2(Gyeonggi R1-2)계통을 최종 선발하였다. 화색은 연한 분홍색이며 화폭은 6.8cm 화고는 4.5cm로서 중형 크기의 스탠다드 형태로 개화하고 화형은 반고심형이며 꽃잎수는 44.8매이고 향기 정도는 약한 편이다. 년간 절화수량은 122본/$m^2$이고 절화장은 66.0cm이며 줄기직경은 6.1mm이고 엽수는 11.0매이며 절화중은 25.6g이고 절화수명은 8.0일이다.

• 농업과학연구
• /
• 제46권1호
• /
• pp.11-25
• /
• 2019

This study was conducted to evaluate the effects of a composite feed additive (CFA) consisting of vitamin C, vitamin E, selenium, and choline on growth performance, carcass characteristics, and meat properties of Hanwoo steers. Twenty-two late fattening steers were randomly assigned to one of two dietary groups, control (commercial concentrate + rice straw) and treatment (commercial concentrate + rice straw + 50 g of CFA). Average daily gain (ADG) was 4.0% higher in treatment than that in control; however, there was no statistically significant difference. The supplementation of CFA had no effect on overall yield or quality traits of carcass. CFA had no effect on chemical composition, water holding capacity, shear force, cooking loss, or myoglobin values in longissimus muscle; however, the content of ${\alpha}$-tocopherol was increased by supplementation of CFA (p < 0.01). The contents of ${\alpha}$-linolenic acid and n-3 fatty acids were higher in treatment group than in control (p < 0.01). The ratio of n-6/n-3 fatty acids was decreased by supplementation of CFA (p < 0.01). The supplementation of CFA had no effect on pH or thiobarbituric acid reactive substances (TBARS) values in longissimus muscle (raw); however, TBARS (cooked) values were lower in treatment group than in control during refrigerated storage (p < 0.01). Thus, the results indicate that the supplementation of CFA (vitamin C + vitamin E + selenium + choline) had some positive effects on the increase in ${\alpha}$-tocopherol and n-3 fatty in longissimus muscle, without any negative effect on growth performance or carcass characteristics of late fattening Hanwoo steers.

• Asian-Australasian Journal of Animal Sciences
• /
• 제32권1호
• /
• pp.137-143
• /
• 2019

Objective: The aim of this study was to compare male and female geese of two contrasting genotypes in terms of fatty acid composition, indexes related to human health, lipid metabolism and oxidative stability of the meat. Methods: The experiment was carried out on total of 120 geese of two different genotypes; the native breed Czech goose (CG) and commercial hybrid Novohradska goose (NG). One-d-old goslings were divided into 4 groups according to genotype and sex, and 8 birds from each group were slaughtered at 8 weeks of age. Results: The effects of the interactions between genotype and sex were observed on growth performance and carcass traits. Final body weight (p<0.001), daily weight gain (p<0.001), daily feed intake (p<0.001), slaughter weight (p<0.001), and cold carcass weight (p<0.001) were highest in NG males and lowest in CG females. The meat fatty acid composition results showed effects of both genotype and sex on the total n-6 and the total polyunsaturated fatty acid (PUFA) content, as well as the PUFA n-6/PUFA n-3 ratio. Regarding genotype, the total n-6, the total PUFA content and the PUFA n-6/PUFA n-3 ratio were higher in CG, and higher values were found in females. In terms of the lipid metabolism, ${\Delta}^5-{\Delta}^6$ desaturase (p = 0.006) was higher in males. The meat oxidative stability results revealed an interaction between genotype, sex and storage time (p<0.001). The highest (13.85 mg/kg) malondialdehyde content was measured in the meat of CG females after 5 days of storage and was presumably related to a higher PUFA content. Conclusion: NG had a relatively higher growth rate and meat oxidative stability, whereas the advantage of CG meat is its favourable fatty acid profile characterized by a higher PUFA content.

• Entomological Research
• /
• 제48권6호
• /
• pp.533-539
• /
• 2018

The RNA interference (RNAi) has been considered as an important genetic tool and applied to develop a new living modified (LM) crop trait which is an improvement of nutrient quality or pest management. The RNAi of DvSnf7 has been used for resistance to LM maize and the Western Corn Rootworm which is a major agricultural pest for the US Corn Belt. Most of the environmental risk assessments (ERA) of double strand RNA (dsRNA) have been performed using in vitro transcript products, and not in vivo expressed product. A large amount of dsRNA was required for the acute toxicity assay of water fleas. Therefore development of massive dsRNA purification techniques is critical. Daphnia, a freshwater microcrustacean, is a model organism for studying cellular and molecular mechanism involved in life history traits and ecotoxicology. In this study, we established the massive dsRNA purification method using Escherichia coli and implemented acute toxicity assays to Daphnia magna. As a result, the present RNase A and DNase I, dsRNA was efficiently purified without any special techniques or equipment. Even though purified dsRNA existed during the acute toxicity test, lethality or abnormal behavior were not observed in D. magna. These results indicated that GFP and DvSnf7 dsRNA were not significantly affected to D. magna due to their lack of sequence matching in its genome. The purification method of dsRNA and the acute toxicity assay of water fleas using purified dsRNA would be suitable for the toxicological studies of LMOs to aquatic non-target organisms.

• International Journal of Advanced Culture Technology
• /
• 제6권4호
• /
• pp.20-28
• /
• 2018

Background: As a result of the South Korean government's medical tourism strategies, the number of UAE inbound medical tourists have the highest annual increase rate among the Middle Eastern countries. The need for medical interpreters in such cases is inevitable, especially considering the languages spoken in both countries differs. The work of a medical interpreter affects patient satisfaction, quality of care, and the UAE patients' revisit intention. However, there is a lack of literature that focuses on the role of medical interpreters for the Arabic-speaking medical tourists in South Korea. The purpose of this study is to assess the satisfaction and the experience of UAE medical tourists in South Korea who have used medical interpretation services. Method: A descriptive exploratory design, including semi-structured interviews, was used in this study to examine factors influencing the satisfaction of UAE patients seeking medical attention in South Korea, who considered travelling exclusively for medical purposes. Eleven UAE medical tourists were selected for the interview using convenience sampling. Results: Two types of interpreters were revealed by the analysis: interpreters with Arabic as their mother tongue and interpreters with Korean as their mother tongue. Patients emphasized the origin of the interpreters and differentiated between the two types of interpreters' professionalism, abilities, and personal skills. However, due to the huge gap between the two cultures, languages, and religions, the UAE patients mainly preferred the Arabic medical interpreters. Further, each type had certain traits that impacted the medical care process and patients' satisfaction. Conclusion: This study shows that the South Korean government needs to focus on the training and assessment system for Arabic language interpreters. Additionally, cultural differences training for the interpreters may help to increase UEA patients' satisfaction.