• Molecules and Cells
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• v.40 no.2
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• pp.109-116
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• 2017

Soybean agglutinin (SBA) is an anti-nutritional factor of soybean, affecting cell proliferation and inducing cytotoxicity. Integrins are transmembrane receptors, mediating a variety of cell biological processes. This research aims to study the effects of SBA on cell proliferation and cell cycle progression of the intestinal epithelial cell line from piglets (IPEC-J2), to identify the integrin subunits especially expressed in IPEC-J2s, and to analyze the functions of these integrins on IPEC-J2 cell cycle progression and SBA-induced IPEC-J2 cell cycle alteration. The results showed that SBA lowered cell proliferation rate as the cell cycle progression from G0/G1 to S phase (P < 0.05) was inhibited. Moreover, SBA lowered mRNA expression of cell cycle-related gene CDK4, Cyclin E and Cyclin D1 (P < 0.05). We successfully identified integrins ${\alpha}2$, ${\alpha}3$, ${\alpha}6$, ${\beta}1$, and ${\beta}4$ in IPEC-J2s. These five subunits were crucial to maintain normal cell proliferation and cell cycle progression in IPEC-J2s. Restrain of either these five subunits by their inhibitors, lowered cell proliferation rate, and arrested the cells at G0/G1 phase of cell cycle (P < 0.05). Further analysis indicated that integrin ${\alpha}2$, ${\alpha}6$, and ${\beta}1$ were involved in the blocking of G0/G1 phase induced by SBA. In conclusion, these results suggested that SBA lowered the IPEC-J2 cell proliferation rate through the perturbation of cell cycle progression. Furthermore, integrins were important for IPEC-J2 cell cycle progression, and they were involved in the process of SBA-induced cell cycle progression alteration, which provide a basis for further revealing SBA anti-proliferation and anti-nutritional mechanism.

• The Research Journal of the Costume Culture
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• v.22 no.5
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• pp.655-669
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• 2014

This study was to examine the service and the product evaluation factors of Korean internet fashion shopping malls and to suggest marketing implications for Korean internet fashion shopping malls wanting to expand into the Chinese market. This study conducted a questionnaire survey for college female students in Qingdao, China, who have shopped at Korean internet shopping malls, and 310 surveys were used in the final analysis, frequency analysis, factorial analysis, and regression analysis. The results of the study were as follows. First, Most of the respondents answered that they found the Korean internet fashion shopping malls through the internet, and the most purchased item was outer clothing. Second, the system stability and web site structure excellence factors had a positive influence on the service satisfaction for the shopping mall 'S', while the system satisfaction, service efficiency, interactivity and web site structure excellence factors had positive influences on service satisfaction for the shopping mall 'P', and the system satisfaction, service efficiency, interactivity factors had positive influences on service satisfaction for the shopping mall 'N'. Third, examining the correlation between product satisfaction for the shopping mall 'S', 'P', and 'N' with fashion product evaluation factors showed that, design factors and quality excellence factors of the three shopping malls had positive influences on product satisfaction. The results of this research provide useful information in forming an efficient operating system and improving marketing strategies for internet fashion shopping malls planning to enter or having already entered the Chinese market.

• Journal of Distribution Science
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• v.19 no.2
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• pp.37-44
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• 2021

Purpose: O2O (Online to Offline) is an internet-based platform. The purpose of this study is to confirm the effect of service quality of O2O food delivery service on service satisfaction, and whether customer orientation mediates the relationship between service quality and service satisfaction. Research design, data and methodology: This paper surveyed Chinese consumers using the O2O food delivery platform through a questionnaire technique. Smart PLS 3.0 was used to verify the hypothesis of this study. PLS is characterized by the advantage of minimizing measurement errors and maximizing the influence of each factor. Results: It was confirmed that O2O food delivery companies need to increase service quality (information quality, product quality, and social quality, system quality) in order to obtain customer satisfaction. Additionally, the perceived customer orientation was found to completely mediate the relationship between perceived service quality (information quality, product quality) and perceived service satisfaction. Conclusions: The service level of the O2O delivery company to the customer's request when a problem occurs in the customer's order must be raised to increase the customer's satisfaction. For example, timely response to customer inquiries and timely feedback of delivery information to customers during the delivery process should improve the quality of after-sales service.

• Korean Journal of Human Ecology
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• v.19 no.4
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• pp.675-685
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• 2010

This study analyzed risk perception and risk reduction behaviors of male and female college students in their twenties who purchased fashion products in internet shopping malls. It also investigated the relationship between risk perception and risk reduction behavior as well as the ways in which groups, categorized by risk perception, differed in their risk reduction behaviors. The results of this study were as follows: first, seven factors of risk perception were identified. These were product quality, shipping, product image, payment, economic feasibility, fear of other people's reactions, and size. Six types of risk reduction behavior were also identified. These were product comparison, word-of-mouth information search, price search, preference for name-brand, service comparison, and referring to experiences. Next, a correlational analysis of the factors of risk perception and those of risk reduction behavior showed several patterns. The highest positive correlation was between economic risk perception and product comparison behavior. In addition, shipping risk perception was positively correlated with service comparison behavior and product quality and product image had a positive correlation with word-of-mouth information search behavior. Third, customers of internet shopping malls could be categorized into three groups: shipping risk perception group, high risk perception group, and product quality risk perception group. The groups were shown by factor analysis to be significantly different to each other. Finally, risk reduction behavior was investigated according to the different groups of risk perception of the internet shopping malls and the results showed significant differences among groups.

• Journal of KIISE:Software and Applications
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• v.33 no.3
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• pp.277-288
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• 2006

Product line engineering (PLE) is a new effective approach to software reuse, where applications are generated by instantiating a core asset which is a large-grained reuse unit. Hence, a core asset is a key element of PLE, and therefore the reusability of the core asset largely determines the success of PLE projects. A tore asset is a reusable part not a whole system, and supports not only variable functions but also common functions. However, there are limitations to evaluate reusability of core asset that has these unique characteristics. This paper proposes a comprehensive quality system for evaluating the reusability of core assets, based on ISO/IEC 9126. We first identify the key characteristics of core assets, and derive the set of quality attributes that characterizes the reusability of core assets. finally, we define metrics for each quality attribute. In addition, we provide guidelines for applying the metrics and perform a case study based on rental product line. Using the proposed quality system, reusability of core assets can be more effectively and correctly evaluated.

• Journal of the Korea Safety Management & Science
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• v.2 no.3
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• pp.141-150
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• 2000

This study aim is analysis device development for design of experiment with calcium chloride relation used a hardener to search cause of product crack, product reliability improvement building data-base program for computer system of mixture rate, product improvement, and new product development.

• International Commerce and Information Review
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• v.6 no.1
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• pp.25-50
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• 2004

This study attempts to find out what kind of service quality is considered important by customers in using the Internet shopping mall and suggests the way to activate the customer relationship. The findings based on empirical analysis are shown here. First, empirical analysis of the contextual factors such as gender, education, and experience levels, shows that what customers perceive as most important in the product purchase is security in terms of the payment and personal information service. The second important service quality factor perceived by customers is responsiveness, particularly the rapidity and accuracy of response to their needs and wants. The customers also considered price, quality and diversity of the product as being important. Furthermore, there is no big difference among other service quality factors. Second, in the different gender context, there is no significant difference between the genders. However, the male group shows an even distribution of factors valued in the service quality, whereas female respondents placed stronger emphases on particular aspects of service, such as security, response, reliability and product quality. Third, in the context of different education level, the payment method between graduates and non-graduates has a significant difference. That is, the non-graduates prefer the credit card and saving through ATM, while the graduates use dual payment method using credit card and another payment method together. Therefore, the various payment methods should be considered according to the customer type, namely graduates or non-graduates. Fourth, in the context of different experience level, the result of the empirical analysis of the factors of the service quality shows no great difference between experienced and inexperienced customers. Both types of customer perceive security as the most important. To sum up, the service quality perceived by the customers of Internet shopping malls is empirically analyzed in different contexts such as gender, education, and experience. Then, the device for the customer relationship activation is suggested. It can be utilized as a guideline for the continuing diffusion of the Internet shopping mall, giving it a competitive advantage against other companies.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2000.11b
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• pp.413-422
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• 2000

Samples of banana were dried in a two-stage heat pump dryer capable of producing stepwise control of the inlet drying air temperature while keeping absolute humidity constant. Two stepwise air temperature profiles were tested. The incremental temperature step change in temperature of the drying air about the mean air temperature of 30 $^{\circ}C$ was 5 $^{\circ}C$. The total drying time for each temperature-time profile was about 300 minutes. The drying kinetics and color change of the products dried under these stepwise variation of the inlet air temperature were measured and compared with constant air temperature drying. The stepwise air temperature variation was found to yield better quality product in terms of color of the dried product. Further, it was found that by employing a step-down temperature profile, it was possible to reduce the drying time to reach the desired moisture content.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.42 no.2
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• pp.1-8
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• 2019

Network externalities are essentially dynamic in that the value consumers feel about a product is affected by the size of the existing customer base that uses that product. However, existing studies on network externalities analyzed the effects of network externalities in a static way, not dynamic. In this study, unlike previous studies, the impact of network externalities on price competition in a vertically differentiated market is dynamically analyzed. To this end, a two-period duopoly game model was used to reflect the dynamic aspects of network externalities. Based on the game model, the Nash equilibria for price, sales volume, and revenue were derived and numerically analyzed. The results can be summarized as follows. First, if high-end product has strong market power, the high-end product vendor takes almost all benefits of the network externality. Second, when high-end product has strong market power, the low-end product will take over most of the initial sales volume increase. Third, when market power of high-end product is not strong, it can be seen that the effects of network externalities on the high and low-end products are generally proportional to the difference in quality. Lastly, if there exists a strong network externality, it is shown that the presence of low-end product can be more profitable for high-end product vendor. In other words, high-end product vendor has incentive to disclose some technologies for the market entrance of low-end product, even if it has exclusive rights to the technologies. In that case, however, it is shown that the difference in quality should be maintained significantly.

• Journal of Korean Society for Quality Management
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• v.43 no.3
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• pp.373-382
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• 2015

Purpose: In this paper, we developed a reliability index (RI) to efficiently compare reliability of products based on the design, development and production information such as reliability tests, quality, product life-cycle management. RI also can be applied to reliability prediction of a novel product as well as comparison evaluation among existing products. Methods: For evaluating RI, we proposed evaluation process which is composed of five steps. Target modules are selected based on warranty data and correlation analysis. Scores of selected target modules are calculated by scoring function. Finally, weights of RI model are determined by optimization method. Results: This paper presented an empirical analysis based on failure data of mobile devices. In this case study, we demonstrated that there is a direct correlation between evaluated RI and field failure probability of each product. Conclusion: We proposed the index for comprehensive and effective assessment of product reliability level. From the procedure of this study, we expected to be applied for reliability estimation of novel products and deduction of field failure-related factors.