• 에너지공학
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• 제23권2호
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• pp.183-190
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• 2014

국내 가동중원전은 2012년 이후 일반규격품 품질검증 이행 체계 구축을 위해 정책 수립 및 기술 개발, 일반규격품 품질검증 전문기관 양성, 국내 원전 공급사들의 일반규격품 품질검증프로그램 보유 추진 및 원자력 산업계의 전문인력 양성 등을 적극 추진 중에 있다. 아울러 미국 전력연구소(EPRI)의 관련 기술기준을 기반으로 일반규격품 품질검증프로그램 도입 초기에 개발된 안전성(Q) 등급 품목 품질검증 프로세스를 개선하였고, 국내 원전 고유의 원자력 품질등급 체계인 안전성영향(A) 등급 품목을 위해 안전성등급 품목과 차별화시킨 별도의 검증 프로세스를 개발하였다. 결과적으로, 위와 같은 노력을 통해 국내 가동중원전의 일반규격품 품질검증 이행 체계가 구축될 경우, 원전에서 사용하는 기자재의 신뢰성 및 안전성이 향상될 것으로 기대된다.

• 컴퓨터교육학회논문지
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• 제14권3호
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• pp.63-72
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• 2011

사이버 공간에서 학업을 병행하는 직장인 학생에게 강의만족은 매우 역동적이고 다차원적인 과정으로 개개인의 학업 니즈와 능력을 반영된 결과이기도 하다. 본 연구는 사이버 경영대학원에 재학 중인 직장인 학생을 대상으로 교수 학생 간 상호작용, 학생 상호간 상호작용, 몰입, 콘텐츠의 질과 구조화, 실시간 Q&A와 사이버 강의를 보완하는 수단으로서의 오프라인 보충강의 등이 만족도에 미칠 직 간접적 영향 정도를 분석하는 데 목적이 있다. 인과관계 검증에 집중하기 보다는 수강생 입장에서 흥미롭다고 인지된 과목과 어렵다고 판단된 과목을 중심으로 인과관계의 강약 정도를 그룹 별로 비교하였다. 분석결과, 어렵다고 인지된 과목을 중심으로 답한 그룹의 경우 교수 학생 간 상호작용에서 만족도, 콘텐츠품질에서 몰입, Q&A에서 교수 학생 간 상호작용 그리고 Q&A에서 학생 간 상호작용으로 이어지는 경로계수값이 흥미롭다고 인지된 과목을 택한 그룹의 경우보다 더 높은 것으로 나타났다. 반대로 학생 간 상호작용에서 만족도와 콘텐츠 구조에서 몰입으로 이어지는 경로계수값은 흥미롭다고 인지된 과목을 택한 그룹이 더 높은 것으로 나타났다. 이를 토대로 이러닝 설계상의 시사점도 간략히 제시하였다.

• 한국정보시스템학회지:정보시스템연구
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• 제29권4호
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• pp.45-56
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• 2020

Purpose The purpose of this study is to present the direction of efficient e-learning education through the importance and satisfaction survey of learners of non-face-to-face video lectures. Therefore, by grasping the degree of satisfaction of the importance ratio through the IPA analysis method, we try to present improvement measures for insufficient education methods. Design/methodology/approach For IPA analysis, we conducted an online survey of four universities and analyzed 154 samples. The analysis method used SPSS, and through the wordcloud analysis method of R, the suggestions for the non-face-to-face lecture method felt by learners were analyzed to derive implications for improving the quality of education. Findings As a result of the overall satisfaction survey for the entire non-face-to-face class, the factors with the greatest dissatisfaction are listed as follows. Complaints about the adequacy of learning materials and activities (quiz, discussion, assignments, etc.), Complaints about how to use the produced content, and complaints about announcements about class management (lecture schedule, lecture method) were identified in order. The factors of dissatisfaction were clear in the non-face-to-face class where interactive communication was impossible or insufficient. In addition to the lack of quick Q&A, there seems to have been a phenomenon of some neglect.

• 아동학회지
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• 제13권2호
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• pp.217-228
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• 1992

The purpose of this study is to examine the effects of early full-time nonparental care during infancy/toddlerhood on children's socioemotional behaviors during the preschool period. Subjects for this study were 105 three- to five-year-olds from middle-class families in the U. S. A. Children were assigned to one of three groups according to their early care history. Children's social interactions with peers and caregivers during indoor free-play sessions in day care centers were observed for 20 minutes. The head teachers rated the children's social and emotional behaviors on two questionnaires. Mothers completed the Attachment Q-sort for attachment assessment for the preschoolers. In addition, mothers were asked to fill out a questionnaire on their parenting practices. Children who had received full-time nonparental care during infancy and/or toddlerhood were rated by their teachers as being more intellectually competent than children who did not receive full-time nonparental care during first three years of life. They were, however, rated by teachers and were observed by the researcher as being more aggressive than children with no full-time nonparental care. These children were observed to engage in less wandering/onlooking behaviors than children who had not had any full-time nonparental care. Children's attachment security scores and dependency scores did not differ as a function of early nonparental care histories. When the effects of early care patterns, sex of child, and current attachment security to mothers on aggressive behaviors of the preschoolers were examined by a hierarchical regression model, then any "pure" effects of nonparental care and of attachment security on child aggression were minimal after controlling for family background, child care center quality, and maternal childrearing practices. Strong buffering factors for the preschool children (family characteristics, parenting styles, and high quality nonparental care) mediated a possible risk factor of early nonparental care and promoted optimal outcomes for the children.

• Journal of the korean society of oceanography
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• 제32권4호
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• pp.163-170
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• 1997

Some CMP gathers acquired from shallow marine seismic reflection survey in offshore Korea do not show the hyperbolic trend of moveout. It originated from so-called swell effect of source and streamer, which are towed under rough sea surface during the data acquisition. The observed time deviations of NMO-corrected traces can be entirely ascribed to the swell effect. To correct these time deviations, a residual statics is introduced using Genetic Algorithms (GA) into the swell correction. A new class of global optimization methods known as GA has recently been developed in the field of Artificial Intelligence and has a resemblance with the genetic evolution of biological systems. The basic idea in using GA as an optimization method is to represent a population of possible solutions or models in a chromosome-type encoding and manipulate these encoded models through simulated reproduction, crossover and mutation. GA parameters used in this paper are as follows: population size Q=40, probability of multiple-point crossover P$_c$=0.6, linear relationship of mutation probability P$_m$ from 0.002 to 0.004, and gray code representation are adopted. The number of the model participating in tournament selection (nt) is 3, and the number of expected copies desired for the best population member in the scaling of fitness is 1.5. With above parameters, an optimization run was iterated for 101 generations. The combination of above parameters are found to be optimal for the convergence of the algorithm. The resulting reflection events in every NMO-corrected CMP gather show good alignment and enhanced quality stack section.

• Animal Bioscience
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• 제36권10호
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• pp.1488-1498
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• 2023

Objective: α_S1-Casein is more closely associated with milk allergic reaction than other milk protein components. microRNA (miRNA) is a class of small non-coding RNAs that modulate multiple biological progresses by the target gene. However, the post-transcriptional regulation of α_S1-casein expression by miRNA in ruminants remains unclear. This study aims to explore the regulatory roles of miR-380-3p on α_S1-casein synthesis in goat mammary epithelial cells (GMEC). Methods: α_S1-Casein gene and miR-380-3p expression was measured in dairy goat mammary gland by quantitative real-time polymerase chain reaction (qRT-PCR). miR-380-3p overexpression and knockdown were performed by miR-380-3p mimic or inhibitor in GMEC. The effect of miR-380-3p on α_S1-casein synthesis was detected by qRT-PCR, western blot, luciferase and chromatin immunoprecipitation assays in GMEC. Results: Compared with middle-lactation period, α_S1-casein gene expression is increased, while miR-380-3p expression is decreased during peak-lactation of dairy goats. miR-380-3p reduces α_S1-casein abundance by targeting the 3'-untranslated region (3'UTR) of α_S1-casein mRNA in GMEC. miR-380-3p enhances β-casein expression and signal transducer and activator of transcription 5a (STAT5a) activity. Moreover, miR-380-3p promotes β-casein abundance through target gene α_S1-casein, and activates β-casein transcription by enhancing the binding of STAT5 to β-casein gene promoter region. Conclusion: miR-380-3p decreases α_S1-casein expression and increases β-casein expression by targeting α_S1-casein in GMEC, which supplies a novel strategy for reducing milk allergic potential and building up milk quality in ruminants.

• 생명과학회지
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• 제25권8호
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• pp.861-869
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• 2015

가축화된 동물종 중 하나인 개는, 다양한 목적을 위해 인간에 의하여 선택적으로 육종되었다. 개는 많은 품종을 갖고 있고, 특정한 행동과 형태를 갖도록 인공적으로 선택되어 왔다. 개들은 그들의 삶을 안내, 구조 혹은 탐지 등의 특수 목적에 대하여 인간에게 헌신하고 있다. 특수 목적견에게 요구되는 좋은 품성, 이를테면 온순함, 강건성, 그리고 인내심과 같은 특성은 그들의 특수 임무를 수행하는 데 필요하다. 많은 연구들이 우수한 특수 목적견의 선정을 위한 유전적 마커를 찾는 데 집중되었다. 본 연구에서는, 뇌에서 발현함으로써 기능하는 것으로 알려진 총 8개의 유전자(ABAT; 4-Aminobutyrate Aminotransferase, PLCB1; Phospholipase C, Beta 1, SLC10A4; Solute Carrier Family 10, Member 4, WNT1; Wingless-Type MMTV Integration Site Family, Member 1, BARX2; BarH-Like Homeobox 2, NEUROD6; Neuronal Differentiation 6, SEPT9; Septin 9 그리고 TBR1; T-Box, Brain, 1)들의 정량적인 발현 양상을 개의 네 품종의 뇌 조직에서 확인하였다. 특히, BARX2, SEPT9, SLC10A4, TBR1 그리고 WNT1 유전자들은 비글과 진돗개에서 많이 발현되는데 반하여, 삽살이와 세퍼드에서는 반대되는 발현 양상을 보여 주었다. 본 연구의 유전자들에 대한 Gene ontology (GO) 결정을 위하여 DAVID (Database for annotation, visualization and integrated discovery) 분석이 수행되었고, 이러한 유전자들이 뇌 발생과 개체의 지능에 중요한 기능을 제공할 것이라고 예상하였다. 결론적으로, 이러한 결과들을 통하여, 뇌에서의 기능과 관련된 인자들과 관련된 바이오마커를 발굴하는 데 중요한 단서를 제공해 줌과 동시에, 우수한 특수 목적견을 선발하는 데 도움을 줄 것이라 기대한다.