• 대한간호학회지
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• 제23권4호
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• pp.544-554
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• 1993

The study was designed to identify the attitude of nursing students to clinical education through Q-methodology. A C sample was developed through a review of the literature and interviews. Twenty - seven statements made up the finalized Q- sample. This was out of an initial 143 statements developed through consultation with eight professors. The P sample consisted of 25 nursing students in S Health Junior College.0 statements were written on seperate cards and were given to the 25 subjects to sort according to degree of agreement or disagreement. The Q-sorts by each subject were coded and analyzed with QUANL PC Program. The analysis discovered three major attitudes, namely “amicable adaptation” 〈type 1), “Nightingale social service” (type 2), and “realistic occupation pursuit” (type 3). The correlation was .465 between type 1 and type 2, .293 between type 1 and type 3, and .273 between type 2 and type 3. The characteristics of each type were as follows ; Type 1 (amicable adaptation) They satisfied in interpersonal relationships in the clinical setting. They would not dream of becoming Nightingale, but thought of nursing care affirmatively and performed their works faithfully and adapted themselves to the new circumstances easily, Fourteen subjects were classified as type 1. Type 2 (Nightingale: social service) They often dreamed as a child that they would be Nightingale with a white uniform and think that nursing is a gift from heaven. They have an aptitude for nursing care by nature and selected nursing science them-selves. They give care to the sick with pleasure. Seven subjects were classified as type 2. Type 3 (realistic occupation pursuit) They were not satisfied with their nursing practice. First of all they want a stable job, therefore they selected nursing science. They had conflicts in clinical practice, but were responsible for nursing and studied hard. Four subjects were classified as type 3. Through the results of this study, the attitude of nursing students to clinical education could be classified into three types. Therefore it is suggested that clinical education would be more valuable, if it was planned according to an understanding of the attitudes of nursing students to clinical education.

• 한국항공우주학회지
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• 제45권5호
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• pp.393-400
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• 2017

본 논문에서는 회전익 무인항공기의 조종성 평가를 수행하기 위한 가상모의시험용 프로그램을 MATLAB GUIDE(Graphic User Interface Development Environment)를 활용하여 개발하였다. ADS-33E에 기반을 둔 조종성 평가 프로그램은 비행제어시스템을 개발하고 조종성을 평가하는 데에 있어 시간과 비용을 경감시킬 수 있을 것으로 사료된다. 또한, Linear Quadratic Regulator(LQR)기반의 Linear Quadratic Tracker with Integrator(LQTI) 자세제어기를 BO-105C 회전익 항공기에 적용하여 조종성을 평가하고 Q와 R의 가중치에 따른 조종성에 대한 경향을 분석하였다.

• 한국지반신소재학회논문집
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• 제18권3호
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• pp.1-9
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• 2019

본 연구에서는 Fly ash로 매립된 지반에서 쇄석다짐말뚝을 적용하여 지반개량 효과를 확인하고자 하였다. 지반조사 및 콘 관입시험을 통해 Fly ash 매립층의 심도, 강도정수를 산정한 후 STONE C 프로그램을 이용해 개량된 지반의 강도정수 및 이론식을 이용해 대상지반의 지지력과 침하량을 예측하였다. 현장에서 실시한 평판재하시험 결과 쇄석다짐말뚝으로 시공된 Fly ash 지반의 지지력은 설계하중을 상회하였으며, 침하량은 모두 기준치 이내로 만족하였다. 시공 후 콘관입시험에 의한 개량효과를 확인한 결과 GCP시공에 따른 복합지반 형성 및 주변지반의 밀도증가에 따라 콘 관입저항치($q_c$)는 250%~500%가량 증가된 것으로 나타나 Fly ash매립지에서 쇄석다짐말뚝의 지반개량효과가 우수함을 확인할 수 있었다.

• Fisheries and Aquatic Sciences
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• 제19권2호
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• pp.11.1-11.7
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• 2016

In this study, purified peptides from shrimp waste hydrolysates (SWHs) were examined for their inhibitory effects against ${\beta}$-secretase. During consecutive purification using a Sephadex G-25 column chromatography and high performance liquid chromatography on a C18 column, a potent ${\beta}$-secretase inhibitory peptide Asp-Val-Leu-Phe-His (629 Da) was isolated and identified from SWH24 by Q-TOF MS/MS and the $IC_{50}$ value was determined to be $92.70{\mu}M$. The ${\beta}$-secretase inhibition patterns of the purified peptides were found to be competitive. Among synthesized ${\beta}$-secretase inhibitory peptides, Leu-Phe-His had higher ${\beta}$-secretase inhibitory activity than the others. The result of this study suggests that the ${\beta}$-secretase inhibitory peptide derived from SWH24 could be potential candidates to develop nutraceuticals and pharmaceuticals.

• 품질경영학회지
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• 제47권3호
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• pp.479-496
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• 2019

Purpose: The purpose of this research is to develop defense quality evaluation model in order to improve the problem of private sector quality evaluation model and propose the total integrated defense quality management model which enables to evaluate not only large defense industry, but also small-medium industry. Methods: This paper consider the characteristics on ISO 9001 Quality Management System, single PPM, PASS and defense quality and develop defense quality maturity model and index which enables to measure the current quality management level and characteristics and to evaluate operational characteristics in each maturity level for domestic defense industry. Results: From 176 DQMS certified defense industry, the defense quality maturity level is 68,2, C grade. The large defense industry shows, 80.9, A grade; medium industry 69.7, C grade; small-medium industry shows 54.1, D grade. Through the classified types of industries, the current level of quality management of defense industries was diagnosed and the areas to be supplemented for the total quality management were identified. Conclusion: Developed DQMI can be used as the basic information for spreading quality management activities in the defense industry by diagnosing the overall quality management of existing defense industries and quantifying the ambiguity of non-metric measurements and measurement standard that were presented as the threshold of the defense quality management system certification process.

• 한국의료질향상학회지
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• 제5권2호
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• pp.190-201
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• 1998

Background : Medical equipments take a very important role in diagnosis and treatment of disease in modern medicine and effective maintenance of the equipments is a necessary to provide a good health care to the public. After developing a new QC program for effective maintenance of medical equipments and practicing it for a year, we report the results of the new program. Methods : The maintenance data of 9 equipments in 8 categories including a CT Scanner were analyzed with regard to the parts responsible for most frequent failure and cause of the failure. After learning the most frequent failure part and cause of the failure, we developed a new QC program that emphasizes preventive maintenance of the most frequent failure part. We compared the number of failure per year and active rate of each equipment before and after the adoption of the new QC program. Results : The average number of failure per year per equipment was 20.7 before and it decreased by 43% to 11.9 after adoption of the new QC program. The average active rate of the equipments was 92.6% before and it increased by 3.2% to 95.8% after adoption of the new program. Conclusions : The practice of the new QC program appears very useful as it decreased the failure rate and increased the active rate of the equipments.

• 생명과학회지
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• 제13권3호
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• pp.291-297
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• 2003

인간 내생 레트로바이러스 HERV-W는 다발성 경화증 환자로부터 탐지된 MSRV와 연루되어 있다. 인간 태아의 뇌로부터 유래된 cDNA library를 이용하여 PCR법으로 2개의 HERV-W 패밀리(HWP-FB10과 HWP-FB12)를 동정하고 분석하였다. 그들은 HERV-W (accession no. AF009668)와 89%의 염기서열의 유사성을 보였다. Pol 유전자를 아미노산의 서열로 분석해 본 결과 점돌연변이 또는 삽입/결실로 말미암아 frameshift 및 종결코돈을 나타내었다. 유전자정보의 데이터베이스를 이용하여 HERV-W 패밀리간의 분자계통분류도를 작성해 본 결과 HWP-FB10은 인간의 염색체 7q21-22로부터 유래된 AC000064와 매우 가깝게 관련되어 있음을 시사하였다. 이들의 새로운 HERV-W pol 패밀리가 이웃하는 어떤 유전자와 상호 연결되어 있으며, 어떠한 기능을 수행하는지에 대한 전망에 대해 토의하였다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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• pp.636-643
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• 2008

본 연구에서는 지오게이지, 동평판재하시험기 그리고 간이지지력시험기 등과 같은 지반강성도를 평가할 수 있는 시험장치와 현장 다짐도 측정에 가장 많이 사용되는 평판재하시험을 다짐횟수, 함수비 그리고 다짐층 두께 등을 변화해 가면서 현장시험을 수행한 결과, 다음과 같은 잠정 결론을 내릴 수 있었다. 1) 지오게이지와 동평판재하시험기 그리고 간이지지력 시험기에서 측정된 결과는 모두 다짐도 증가에 따른 지반 강성 증가 현상을 잘 반영하는 것으로 나타났다. 2) 함수비에 따른 지반강성 증감 현상은 지오게이지와 간이지지력시험 결과에서만 일부 뚜렷하게 나타났으며, 동평판재하시험이나 기준 시험인 평판재하시험은 함수비 증감에 따라 지반강성 증감 현상이 뚜렷하게 나타나지 않았다. 3) 다짐충 두께 변화에 따른 지반강성도 평가시험 결과 본 시험에서 수행한 지오게이지, 동평판재하시험, 간이지지력 시험은 물론 기준시험인 평판재하시험의 경우에도 일정한 경향이 뚜렷하게 나타나지 않아 이에 대한 추가적인 연구가 필요할 것으로 판단된다. 본 연구에서는 간편하고 신속한 시험이 가능한 다양한 지반강성평가 시험장치를 이용해 현장에서 다양한 조건의 지반에 대해 다짐도 평가 시험을 수행한 결과, 함수비 및 다짐두께가 일정한 경우 다짐횟수 증가에 따라 모든 시험 결과가 지반강성도가 증가하는 것으로 나타났다. 따라서, 추후 다양한 지반조건에 대해 다양한 시험을 수행하여 다짐도 및 지반강성도의 연관성에 대한 자료가 축적된다면, 본 시험에서 수행한 시험방법으로도 현장 다짐도 측정이 가능할 것으로 판단된다.

• Journal of Microbiology and Biotechnology
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• 제12권6호
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• pp.972-978
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• 2002

Streptomyces sp. AD001 is a Gram-positive soil actinomycetes secreting an uncharacterized 2,4-dichlorophenol (DCP) oxidizing enzyme, whose activity is similar to the previously known Actinomycetes lignin-peroxidase (ALiP). This extracellular peroxidase was purified from Streptomyces sp. AD001 as a single protein band on an SDS-PACE by ammonium sulfate fractionation, Q-sepharose, concanavalin A, and Bio-Gel HTP column chromatographies. The molecular mass of the purified peroxidase was determined by SDS-PAGE to be 45.2 kDa, and 49.7 kDa with MALDI-TOF-MS, respectively. The highest level of peroxidase activity was observed at pH 7.5 and $30^{\circ}C$. The amino terminal sequence of the purified peroxidase (G-E-P-E-E-G-N-V-D-G-T-L) showed no significant homologies to my known proteins, suggesting that Streptomyces sp. AD001 may secrete a novel kind of bacterial peroxidase Initial rate kinetic data of the 2,4-DCP oxidation were best modeled with a random-binding bireactant system.

• 한국물환경학회지
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• 제31권6호
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• pp.653-664
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• 2015

TPLMS (Total water pollutant load management system) that is the most powerful water-quality protection program have been implemented since 2004. In the implementation of TPLMS, target water-quality and permissible discharged load from each unit watershed can be decided by water-quality modeling. And NPS (Non-point sources) discharge coefficients associated with certain (standard) flow are used on estimation of input data for model. National Institute of Environmental Research (NIER) recommend NPS discharge coefficients as 0.15 (Q₂₇₅) and 0.50 (Q₁₈₅) in common for whole watershed in Korea. But, uniform coefficient is difficult to reflect various NPS characteristics of individual watershed. Monthly NPS discharge coefficients were predicted and estimated using surface flow and water-quality from HSPF watershed model in this study. Those coefficients were plotted in flow duration curve of study area (Palger stream and Geumho C watershed) with monthly average flow. Linear regression analysis was performed about NPS discharge coefficients of BOD, T-N and T-P associated with flow, and R² of regression were distributed in 0.893~0.930 (Palger stream) and 0.939~0.959 (Geumho C). NPS Discharge coefficient through regression can be estimated flexibly according to flow, and be considered characteristics of watershed with watershed model.