• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2013.04a
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• pp.528-532
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• 2013

In this study, an analytical model of micro-beam structure including thermoelastic damping with irregularly distributed masses is investigated. The significance of thermoelastic damping for micro-scale mechanical resonators is evaluated to design -with high quality factor(Q-factor). The beam model of this work is based on Euler-Bernoulli beam theory. In order to determine the natural frequency of the model, energy method is applied. Also, the thermoelatic damping effects are considered by using heat conduction equations, and the Q-factor can be determined. To derive the equation of motion, non-dimensionalization is employed for systematic analysis. Results of the model are verified, and present mode shapes and Q-factors for the micro-beam with thermoelastic damping including random point masses.

• Analytical Science and Technology
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• v.32 no.1
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• pp.24-34
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• 2019

The safety of food is occasionally questionable, as there have been some reports of products contaminated with illegal adulterants. In this study, the presence of 16 sedative-hypnotics and sleep inducers in dietary supplements was determined by ultra-high-performance liquid chromatography with UV detection (UPLC-UV) and quadruple Orbitrap mass spectrometry (Q-Orbitrap-MS). The UPLC method was validated, providing a linearity (R2) of more than 0.999, and LODs and LOQs that ranged from 0.2 to 0.5 and 0.6 to $1.5{\mu}g\;mL^{-1}$, respectively. The repeatabilities were 0.2-8.4 % (intra-day) and 0.3-4.5 % (inter-day), and the accuracies were 89.0-117.0 % (intra-day) and 87.8-111.9 % (inter-day). The mean recoveries of the spiked samples ranged from 98.7 to 107.3 %. The relative standard deviation (%RSD) of the stability was less than 2.4 %. Using the developed method, one sedative-hypnotic compound, phenobarbital, was detected in one of the nineteen samples tested. In addition, the major characteristic fragment ions of each target compound were confirmed using Q-Orbitrap-MS for higher accuracy. Monitoring the presence of these 16 sedative-hypnotics and sleep inducers in dietary supplements should be pursued in the interest of human health, and the results of this study confirmed that the developed method has value for this application.

• Journal of Broadcast Engineering
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• v.21 no.1
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• pp.60-65
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• 2016

This paper introduces the non-local means (NLM) algorithm for image denoising, and also introduces an improved algorithm which is based on the principal component analysis (PCA). To do the PCA, a covariance matrix of a given image should be evaluated first. If we let the size of neighborhood patches of the NLM S × S², and let the number of pixels Q, a matrix multiplication of the size S² × Q is required to compute a covariance matrix. According to the characteristic of images, such computation is inefficient. Therefore, this paper proposes an efficient method to compute the covariance matrix by sampling the pixels. After sampling, the covariance matrix can be computed with matrices of the size S² × floor (Width/l) × (Height/l).

• Journal of Forest and Environmental Science
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• v.29 no.3
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• pp.219-225
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• 2013

The correlation between disturbance intensity and stand development was evaluated on the basis of natural forest community type classification in areas of Baekhaksan (more disturbed area) and Hwangaksan (less disturbed area). The vegetation data were collected by point-centered quarter sampling method, and they were subjected to cluster analysis for classifying community types and to analysis of species composition and species diversity for reviewing ecological characteristics. By the method of cluster analysis, natural forests of Baekhaksan were classified into Quercus forest community, Pinus densiflora community, Q. variabilis community, and Q. mongolica community. Those of Hwangaksan were divided into P. densiflora community, Q. mongolica community, Q. forest community, and Mixed mesophytic community. It is presumed that more developed and less disturbed forest area shows multiple species community pattern and more diversified structure than less developed and more disturbed forest area. In Korean peninsula, the abundance of red pine may play an important indicator to estimate the developmental pattern of the forest after artificial disturbance. The overall evaluation indicated that less disturbed Hwangaksan area had more developed stand pattern with mixed mesophytic community, more complicated species composition, and higher species diversity than Baekhaksan area.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.2D
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• pp.191-203
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• 2008

According to a characteristic analysis of traffic accidents of industrial vehicles (RTSA 2007), the occurrence rate and lethality per 10,000 vehicles is 6.7 times higher and 5.3 times higher than that of non-industrial vehicles respectively. For the recent 10 years, in contrast to the 1.5% decrease of the annual rate of entire traffic accidents, the accident rate of industrial vehicles have been increasing 2.0% on the annual average. For the recent 10 years, the accidents of a freight truck and bus have been steadily falling off. But, in the case of a taxi, it has constantly been rising 5.6%. In these situations, the countermeasures to decrease the accident rate are suggested by grasping the inclination of taxi drivers through Q analysis which is character and psychology analysis method.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38A no.3
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• pp.224-239
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• 2013

An exact performance analysis of an ML detector for a 2-dimensional rotation-transform aided QPSK system operating over an impulsive noise environment is presented using Rieman integrals of a two-dimensional Gaussian Q-function over Voronoi cells. A set of interesting features of the Voronoi cells is also characterised systematically. An optimum rotation angle yielding the minimum BER is also studied. The differences between the proposed exact method and the previous approximate analysis method are investigated in terms of the corresponding BERs and the derived optimum angles.

• Proceedings of the KIEE Conference
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• 1999.07a
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• pp.167-169
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• 1999

This paper presents the d-q axis inductances calculations method of Interior Permanent Magnet Synchronous Motor(IPMSM) by using Finite Element(FE) analysis. The inductances of d-q axis in IPMSM, which is the function of current magnitude and phase angle are computed by energy dual method. The appropriateness of the proposed FE analysis has been verified by comparing with experimental results.

• Food Science of Animal Resources
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• v.39 no.1
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• pp.1-12
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• 2019

The objective of this study was to establish an optimized 1D $^1H$ quantitative nuclear magnetic resonance (qNMR) analytical method for analyzing polar metabolites in meat. Three extraction solutions [0.6 M perchloric acid, 10 mM phosphate buffer, water/methanol (1:1)], three reconstitution buffers [20 mM 3-morpholinopropane-1-sulfonic acid, 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid, phosphate buffer], and two pulse programs (zg30, noesypr1d) were evaluated. Extraction with 0.6 M perchloric acid and 20 mM phosphate resulted in a stable baseline and no additional overlap for quantifying polar metabolites in chicken breast. In qNMR analysis, zg30 pulse program (without water-suppression) showed smaller relative standard deviation (RSD) and faster running time than noesypr1d (water-suppression). High-performance liquid chromatography was compared with qNMR analyses to validate accuracy. The zg30 pulse program showed good accuracy and lower RSD. The optimized qNMR method was able to apply for beef and pork samples. Thus, an optimized 1D $^1H$ qNMR method for meat metabolomics was established.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7621-7628
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• 2013

Human epidermal growth factor receptor (HER) status is an important prognostic factor in breast cancer. There is no globally accepted method for determining its status, and which method is most precise is still a matter of debate. We here analyzed HER2 mRNA expression by quantitative reverse transcription-PCR (qRT-PCR) and HER2 DNA amplification using multiplex ligation-dependent probe amplification (MLPA). In parallel, we performed a routine evaluation of HER2 protein by immunohistochemistry (IHC). To assess the accuracy of the RT-PCR and MLPA techniques, a combination of IHC and fluorescence in situ hybridization (FISH) was used, substituting FISH when the results of IHC were ambiguous (2+) and for those IHC results that disagreed with MLPA and qRT-PCR, this approach being termed IHC-FISH. The IHC results for four samples were not compatible with the MLPA and qRT-PCR results; the MLPA and qRT-PCR results for these samples were confirmed by FISH. The correlations between IHC-FISH and qRT-PCR or MLPA were 0.945 and 0.973, respectively. The ASCO/CAP guideline IHC/FISH correlation with MLPA was (0.827) and with RT-PCR was (0.854). The correlations between the IHC results (0, 1+ as negative, and 3+ as positive) and qRT-PCR and MLPA techniques were 0.743 and 0.831, respectively. Given the shortcomings of IHC analysis and greater correlations between MLPA, qRT-PCR, and FISH methods than IHC analysis alone with each of these three methods, we propose that MLPA and real-time PCR are good alternatives to IHC. However a suitable cut-off point for qRTPCR is a prerequisite for determining the exact status of HER2.

• Analytical Science and Technology
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• v.30 no.1
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• pp.10-19
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• 2017

Anabolic steroids have similar structures to testosterone, both of which promote the growth of muscle mass and increase strength. However, the side effects of anabolic steroid use may lead to heart attacks or strokes. Additionally, the excessive use of steroids inhibits the production of the sex hormones in the body via a negative feedback loop, which results in testicular atrophy in males and amenorrhea in females. Currently, the method of choice used to test for the presence of anabolic steroids is GC-MS. However, GC-MS methods require chemical derivatization of the steroid sample to ensure compatibility with the analytical method; therefore, analysis of many different samples is difficult and time consuming. Unlike GC-MS, the liquid chromatography-quadrupole-time of flight mass spectrometry (LC-Q-TOF-MS) method is suitable for many samples. Twenty-two different anabolic steroids were analyzed by LC-Q-TOF-MS with various collision energies (CE). Accurate mass spectral data were obtained using a Q-TOF-MS equipped with an electro-spray ionization source and operated in the positive MS/MS mode for several classes of steroids that are often the targets of testing. Based on the collected data, fragmentation pathways were carefully elucidated. The high selectivity and sensitivity of the LC-Q-TOF-MS instrument combined with these fragmentation pathways offers a new approach for the rapid and accurate screening of anabolic steroids. The obtained data from the 22 different anabolic steroids will be shared with the scientific community in order to establish a library to aid in the screening of illegal anabolic steroids.