• Title/Summary/Keyword: Pyrrolidine-2-thione

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Microwave Assisted N-Alkenyl Condensation between Pyrrolidine-2-thione and Various Aldehydes

  • Kim, Ki-Won;Lee, Ho-Joon;Kim, Chung-Gi;Park, Mi-Ja;Kwon, Tae-Woo
    • Bulletin of the Korean Chemical Society
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    • v.29 no.3
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    • pp.604-608
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    • 2008
  • A series of N-alkenyl pyrrolidine-2-thiones were synthesized by the reaction between pyrrolidine-2-thione and various aldehydes such as n-propanal, isopropanal, n-butanal, n-hexanal, n-octanal and phenylacetaldehyde in 32-86% yields using microwave irradiation technique. Only one structural E isomers were predominantly formed within 15 minutes in chlorobenezene?/p-toluenesulfonic acid monohydrate.