• 한국식물병리학회지
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• 제14권6호
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• pp.622-624
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• 1998

During the course of study on plant parasitic nematodes associated with medicinal herbs in Korea, high population of different stages of citrus nematode, Tylenchulus semipentrans was found in association with Pyrola japonia Klenze in Imsil, Chunbuk province. The second stage larvae and males were isolated from rhizosphere soil ; immature and mature females were detached from the roots of infested plants of Pyrola japonica. Besides citrus it has been reported to parasitize on roots of Syringa vulgaris, Diospyros lotus, olive, grapevine, and pear in different parts of the world. This is the first record of T. semipenetrans parasitized on a medicinal plant, Pyrola japonica.

• 생약학회지
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• 제38권1호
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• pp.45-49
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• 2007

Chinese crude drug "Lu-ti-cao"(鹿蹄草) has been used as a remedy for beriberi, cut bleeding, snake bite, etc. In Korea, the drug is called "Nok Je Cho" and has been used as a folk medicine of the same effect as that of Chinese equivalent. The original plant of this drug has not yet been as certained. To clarify the botanical origin of "Nok Je Cho", the morphological and anatomical characteristics of the leaves of Pyrola species growing in Korea, i.e. P. incarnata, P. japonica, P. minor, P. renifolia, P. secunda were studied. As a result, it was clarified that "Nok Je Cho" was the leaf of Pyrola japonica and Pyrola minor.

• 한국자원식물학회지
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• 제20권2호
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• pp.193-200
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• 2007

국내 분포하는 것으로 알려진 노루발과 7분류군의 화분에 대하여 분류학적 가치를 파악하기 위하여 광학현미경과 주사전자현미경으로 관찰하였다. 성숙한 화분의 단위(pollen unit)는 Pyrola속의 호노루발[P. dahurica(Andres) Kom.], 분홍노루발[P. incarnata(DC.) Fisch. ex Kom.], 노루발(P. japonica Klenze ex Alefeld), 주걱노루발(P. minor L.), 콩팥노루발(P. renifolia Max.)에서 사립(tetrad), Orthilia속의 새끼노루발[P. secunda(L.) House]에서 단립(monad), Chimaphila속의 매화노루발(C. japonica Miq.)에서 사립들이 엉성하게 모여 다립(polyad)을 형성하였다. 이와 같이 노루발과의 성숙한 화분의 단위는 과내 속을 구분하는 중요한 형질로 판단되었으며, 이를 근거로 새끼노루발의 학명은 Pyrola secunda L.보다는 Orthilia secunda(L.) House가 적합한 것으로 생각되었다. 화분의 크기와 삼공구형(tricolporate)인 발아구의 크기, 표벽 무늬는 분류군 간에 다소 차이를 나타냈으며, 호노루발과 콩팥노루발, 분홍노루발, 주걱노루발의 표면무늬는 기존 보고와 다소 상이하였다. 본 연구에서 취급된 분류군들의 화분은 성숙한 화분의 구성단위가 각기 사립에서 단립과 다립으로, 발아구의 형태가 공구형에서 공형으로의 진화경향성을 추론할 수 있었다.

• The Korean Journal of Ecology
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• 제22권6호
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• pp.349-354
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• 1999

The spatial distributions of allelic frequencies and ecological traits by randomization were studied in the natural population of two species (Pinus rigida and Pyrola japonica). Both species showed significant positive spatial autocorrelation as measured by Moran's I. In P. rigida, the genetic similarity was shown in individuals within up to a scale of 18 m distance and this is partly due to combination of pollen and seed dispersal by wind or men. In P. japonica, significant spatial autocorrelation was consisted of a scale of 8 m intervals. These population structure in the distribution of allelic frequencies is related to mating systems such as outcrossing and vegetative spread. The results also indicate that positive species associations between P. rigida and P. japonica can occur when both species select the same habitat or require the same environmental conditions.

• 생명과학회지
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• 제16권6호
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• pp.989-993
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• 2006

우리나라 전국 산지에서 쉽게 구할 수 있는 노루발풀을 건조시켜 80% ethanol 추출물과 여러 가지 용매 분획물의 미생물 증식 억제 효과에 대해서 검색하였다. 노루발풀의 80% ethanol 추출물은 그람 양성균 B. subtilis에서 농도 의존적으로 항균활성을 나타내는 반면 그람 음성균 E. coli에서는 활성이 나타나지 않았다. 노루발풀의 80% ethanol 추출물을 용매 분획하여 얻은 분획물 중 hexane층에서 항균활성이 나타나는 것을 확인하였다. 노루발풀의 항균활성 물질을 검색하기 위한 목적으로 hexane 분획물을 silica gel column chromatography, prep. TLC 및 HPLC를 실시하였으며 그 결과, peak I의 단일 물질이 노루발풀의 B. subtilis에 대한 항균활성을 나타내는 물질임을 확인할 수 있었다.

• Archives of Pharmacal Research
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• 제24권6호
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• pp.522-523
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• 2001

A new naphthoquinone, 5,8-dihydro-2,7-dimethyl-[1,4]naphthoquinone (1), which was named 5,8-dihysrochimaphilin, isolated from an ethyl acetate soluble fraction from the root of Pyrola japonica, together with chimaphilin (2). Compound 1 was transformed rapidly to 2 upon exposure to air by HPLC analysis. This fact supported that chimaphilin (2) may be an artifact from 1 .

• The Korean Journal of Ecology
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• 제13권1호
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• pp.59-66
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• 1990

Changes in water potential, lethal temperature and carbohydrate content in the leaves of wintergreen (Pyrola japonica) during overwintering were investigated. Leaf water potential was kept at -2 bars in the tender stage before October, decreased to -46 bars in the dormancy stage and increased to -2 bars again after dehardening Lethal temperatures of the leaf tissue were $-7^{\circ}C$ in the tender stage and $-7^{\circ}C$ in the dormancy stage, but did not recover up to that of the tender stage during dehardeding. Peak of soluble sugar content coincided with the nadir of the leaf water potential. There were close relationships among daily minimum air-temperature, leaf water potential and lethal temperature in changing patterns during overwintering.

• 약학회지
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• 제40권2호
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• pp.225-229
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• 1996

The cytotoixic effect of Pylorae Herba (Pyrola japonica Klenze) against L1210 and K-562 cells was studied in vitro. The methanolic extract of Pylorae Radix was add ed to the culture of L1210 cells and K-562 cells for the cytotoxic activity and the ED50 values of hexane, ethylacetate, buthanol and water fractions from methanolic extract were determined using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazoliumbromide) assay. The active constituent isolated by bioassay guided fractionation followed by purification gave rise to a yellow needle crystal and was clarified to be chimaphilline by the comparison with the published data. The average life spans with it were not prolonged significantly on tumor growth in hybrid female mouse (BDF1-KIST) inoculated subcutaneously with P388 cells.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.256.2-256.1
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• 2003

Six known phenolic glycosides. hyperin(2), androsin(3), homoarbutin(4), isohomoarbutin(4a), pirolatin(7) and monotropein(6), together with two new compounds, (1)[mp. 215 - 217$^{\circ}C$, C$\sub$23/H$\sub$32/O$\sub$11/] and (5)[mp. 121 -123$^{\circ}C$, C$\sub$18/H$\sub$26/O$\sub$8/] were isolated from the BuOH fraction of Pyrola japonica(Pyrolaceae). The structures of the known compounds were determined by chemical and spectroscopic methods. (omitted)

• 한국동물학회:학술대회논문집
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• 한국동물학회 1997년도 한국생물과학협회 학술발표대회
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• pp.291.1-291
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• 1997

No Abstract, See Full Text