• Bulletin of the Korean Chemical Society
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• 제22권10호
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• pp.1141-1144
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• 2001

• 대한한의진단학회지
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• 제19권2호
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• pp.91-100
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• 2015

Objectives The aim of this study is to develop a structured clinical protocol related with acquisition of radial pulse wave in the randomized, $2{\times}2$ cross-over design, and cold-heat intervention trial for a pilot and preliminary study. Methods The protocol was contrived based on wide ranging literature searches for cold-heat intervention experiments and radial pulse diagnoses. Results Sample size of 60 subjects was calculated based on an effect size derived from the previous study designed to detect the pre-post cold-heat differences in the radial pulse. Each subjects will be randomly assigned to the cold (first) to heat (last) group (n=30) or heat (first) to cold (last) group (n=30). All subjects will fill out a case report form and questionnaires related with pattern identification, dietary patterns, sleep quality, and physical activity will be surveyed and used as a secondary outcomes. Safety assessment will be reported at the final stage. Conclusions This protocol will provide an additional reference to future studies related with observation of radial pulse during any interventions and also expect to be used as a guideline for acquisition of reliable radial pulse wave data.

• 대한한방부인과학회지
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• 제29권3호
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• pp.23-34
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• 2016

Objectives: The purpose of this study was to survey the status of clinical use of a pulse tonometric device (PTD).Methods: We searched domestic and international articles using the PTD from online medical databases including OASIS, RISS, DBpia and PubMed. We selected articles on clinical application of PTD but excluded articles on mechanical design or software programming for developing a new PTD. Finally we found 13 articles and classified the articles according to the disease of clinical study.Results: Out of the 13 articles, 5 were focused on the dysmenorrhea. Three articles were focused on the infertility, two article were focused on the post mastectomy. According to the results, the pulse energy has been widely used in research as the primary outcome.Conclusions: We found out that until now the researches on clinical application of PTD mainly had been performed for producing a variety of PTDs. This results of this study will be used as a useful information during perform a clinical study and clinics. We suggest that the standard operating procedure for PTD will be developed, and researches for development and its application of various new contents will be performed.

• Journal of Electrical Engineering and Technology
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• 제9권6호
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• pp.1978-1987
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• 2014

Power requirement to the induction heating system varies during the heating process. A closed loop control is required to have a smooth control over the power. In this work, a constant frequency pulse density modulation based power tracking control scheme for domestic induction heating system is developed using the Fuzzy Logic Controller. In the conventional power modulation schemes, the switching losses increase with the change in the load. The proposed pulse density modulation scheme maintains minimum switching losses for the entire load range. This scheme is implemented for the class-D series resonant inverter system. Fuzzy logic controller based power tracking control scheme is developed for domestic induction heating power supply for various power settings. The open loop and closed loop simulation studies are done using the MATLAB/Simulink simulation tool. The control logic is implemented in hardware using the PIC16F877A microcontroller. Fuzzy controller tracks the set power by changing the pulse density of the gate pulses applied to the inverter. The results obtained are used to know the effectiveness of the fuzzy logic controller to achieve the set power.

• Earthquakes and Structures
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• 제10권1호
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• pp.239-260
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• 2016

Tuned mass dampers (TMDs) have been frequently proposed to mitigate the detrimental effects of dynamic loadings in structural systems. The effectiveness of this protection strategy has been demonstrated for wind-induced vibrations and, to some extent, for seismic loadings. Within this framework, recent numerical studies have shown that beneficial effects can be achieved by placing a linear TMD on the roof of linear elastic structural systems subjected to pulse-like ground motions. Motivated by these positive outcomes, closed-form design formulations have been also proposed to optimize the device's parameters. For structural systems that undergo a near-fault pulse-like ground motion, however, it is unlikely that their dynamic response be linear elastic. Hence, it is very important to understand whether such strategy is effective for inelastic structural systems. In order to provide new useful insights about this issue, the paper presents statistical results obtained from a numerical study conducted for three shear-type hysteretic (softening-type) systems having 4, 8 and 16 stories equipped with a linear elastic TMD. The effectiveness of two design procedures is discussed by examining the performances of the protected systems subjected to 124 natural pulse-like earthquakes.

• Journal of Magnetics
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• 제18권1호
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• pp.14-20
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• 2013

For the treatment of osteoarthritis, pulsed electromagnetic field stimulus has been suggested as a useful therapeutic method in rehabilitative medicine. Most studies have been performed under low-frequency and low-energy to find out biological properties for stimulating chondrocyte with pulsed magnetic field. In this study, the effect of strong pulse magnetic field on the human chondrosarcoma cells (SW-1353) has been investigated by means of cell counting, morphologies, and gene expression of cartilage extracellular matrix genes. The SW-1353 cells were exposed under the field intensities of 270, 100, 55, 36, and 26 mTesla during 6 hours a day in 5 consecutive days. The pulse magnetic field with an LRC oscillating signal has the pulse width of 0.126 msec and stimulation period of 1 sec. For the 270 and 100 mTesla stimulation, the cell proliferation significantly increased in 21-24% as compared with the non-stimulated cells. Gene expression of cartilage extracellular matrix genes (ACAN, COMP and COL2A1) was assayed by quantitative real time-PCR method. The ACAN gene expression showed a significant brightness, which means the increase on gene expression, compared with the non-stimulated cells. Our results suggest that the strong pulse magnetic field stimulation can be utilized to accelerate cell proliferation and gene expression on human chondrosarcoma cells.

• 한국광학회:학술대회논문집
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• 한국광학회 1991년도 제6회 파동 및 레이저 학술발표회 Prodeedings of 6th Conference on Waves and Lasers
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• pp.64-64
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• 1991

The interaction of high-intensity, focused, nanosecond laser light with matter results in the production of high-temperature plasma, which in turn emits an intense pulse of x rays. The x-ray spectrum consists of strong line components of several keV photon energy and broad continuum. Such an x-ray source provides many advantages over conventional ones for many applications. Pulse nature of the x-ray emission is well-suited for studying transient phenomena and for imaging living biological specimen. Recent experiments have also shown that the laser plasma x ray may be used for x ray lithography. These studies and other applications will be discussed in detail.

• 전기학회논문지
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• 제57권12호
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• pp.2351-2357
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• 2008

Noninvasive radial artery pulse wave has been widely used not only for the pulse wave analysis(PWA) itself but also for assessment of arterial stiffness with estimated aortic pulse wave from peripheral pulse wave. However, it has been found that the deformation of pulse shape can be caused readily by changing measuring position, indentation pressure, and so on. So, in this study, we have developed a system which can measure radial pulse wave and skin displacement simultaneously while the indentation body goes down to occlude subject's radial artery. This system can be divided into a measuring apparatus part, an indentation control hardware part, a data acquisition part and a control and computation part. And, the measuring apparatus consists of an arm-rest, a step motor, an indentation body, a laser displacement sensor(LK-G30, Keyence Co.) and pulse wave sensor. Under load-free condition and radial artery loaded condition, the evaluation of developed system has been performed. From these results, we can conclude: 1) The developed system can control the indentation body quantitatively and the adopted laser displacement sensor shows linear output characteristic even with skin as a reflector. 2) This system can measure the pulse wave and the displacement of indentation body, that is, skin displacement simultaneously at each specific level of indentation body. 3) This system can provide the number of motor steps used to get down the indentation body, the measured skin displacement, the calculated indentation pressure, the calculated pulse pressure and the pulse waveform as well as the information generated by combining these with each others. 4) This system can reveal the relationship between the morphological changes of pulse wave and the estimated displacement of radial artery wall by indentation. Consequently, the developed system can furnish more abundant information on radial artery than previous diagnosis systems based on tonometric measurement. In further study, we expect to setup the standard measuring process and to concrete the algorithm for the estimation of radial artery's diameter and of displacement of radial artery's wall. Furthermore, with well designed clinical studies, we hope to turn out the usefulness of developed system in the field of cardiovascular system evaluation.

• 한국한의학연구원논문집
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• 제18권1호
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• pp.59-74
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• 2012

Objective : The aim of this study is to investigate current status of Sasang constitutional medicine researches and to provide source in setting a development strategy and making a policy on the Sasang constitutional medicine. Method : This study analyzed trends in research as represented in the 142 articles of Korea Institute of Oriental Medicine in the field of Sasang constitution medicine from 2007 to 2010. Result : The main themes of studies were Sasang constitution clinical study (68, 47%) and developing instruments for measuring diagnosis (48, 33%), especially pulse diagnosis (25, 17%). Genetic researches and trends studies on Sasang constitutional medicine were respectively 17 (12%) and 8 (5%). As a result, Korea Institute of Oriental Medicine established Sasang clinical information bank, and discovered clinical character of Sasang constitution to develope various diagnosis tools include constitution survey form and pulse diagnosis instrument. Genetic researches also discover constitution related genes such as FTO and MC4R, and explore association between heredity and Sasang constitution. Conclusion : The above mentioned achievements of Korea Institute of Oriental Medicine were limited to diagnosis process, unquestionably studies for reproducibility and authenticity of constitution diagnosis were important mission of Sasang constitutional medicine. However, to develop the advance of Sasang constitutional medicine, not only constitution diagnosis but also constitutional treatment studies should be conducted.

• 대한의용생체공학회:의공학회지
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• 제31권4호
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• pp.328-334
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• 2010

Over the past few years, a considerable number of methods have been proposed and applied for the classification of photoplethysmography (PPG). Most of the previous studies, however, focused on the qualitative description of the pulse type according to specific disease and thus provided ambiguous criteria to interpreters. In order to screen out this problem, we present a quantitative method for the pulse type classification including the second derivative of photoplethysmography (SDPTG). In the PPG signal, we have classified the signal as 4 types using the position and the presence of the dicrotic wave. In addition, we have categorized the SDPTG signal as 7 types using the position and the presence of "c" and "d" wave and the sign of "c" wave. In order to check the efficacy of the proposed pulse type classification rule, we collected pulse signals from 155 subjects with different ages and sex. From the correlation analysis, Class 1(p<0.01) and Class 2(p<0.01) in the PPG signal are significantly correlated with ages. In a similar manner Class A(p<0.01), Class C(p<0.05), Class D(p<0.01), and Class F(p<0.01) in the SDPTG signal are considerably correlated with the ages. From these observations, and some earlier ones [4], [5], we can conclude that since the newly proposed method has objectivity and clarity in pulse type classification, this method can be used as an alternative of previous classification rules including similar age-related characteristics.