• 대한수의학회지
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• 제45권4호
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• pp.575-579
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• 2005

A 6-month-old male Poodle was referred with chief complaint of dysponea and cough. Cyanosis was not detected. This dog was diagnosed as a case of canine patent ductus arteriosus (PDA) by X-ray and ultrasonography. Diuretics and bronchodialators were administered for 4 weeks. Clinical symptoms were not improved. Thoracotomy was done at right recumbent position. The length of ductus arteriosus was 8 mm and the diameter was 6 mm, respectively. Double ligation was performed in surgery. Continuous cardiac murmur, cough and strong femoral pulsation were disappeared after surgery. The diameters of the pulmonary artery and vein found to normal by X-ray on 10 days after operation. The diameter of the aorta measured to be larger than that of the main pulmonary artery by ultrasonography. The fractional shortening (FS) on 10 days after surgery was 17.32% by ultrasonography. The needle-acupuncture therapy was used in acupoints BL-15 as local point plus PC-6, HT-7 and HT-5 as distant points for 3 days (15 min/once/a day). The FSs were increased to 21.31% and 29.44% at 1 and on 3 days after acupuncture, respectively. The present patient was a case of typical canine PDA that showed favorable therapeutic responses by surgery combined with needle-acupuncture treatment.

• Journal of Digestive Cancer Research
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• 제1권2호
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• pp.108-110
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• 2013

전체 정맥혈색전증 환자의 20% 이상이 암과 관련이 있고, 암 환자에 있어 혈색전증은 두 번째 사망 원인으로 작용하고 있어 이에 대한 효과적인 예방과 치료가 사망률을 감소시킬 수 있는 것으로 알려져 있다. 혈색전증 진단에 있어 혈액검사로 D-dimer 측정 및 영상검사로 도플러 초음파, 전산화단층혈관 촬영술을 사용한다. 치료 약제로 경구 비타민 K 길항제가 사용되었으나, 최근에는 정기적인 모니터링이 필요하지 않은 약제들이 새롭게 사용되고 있다. 저자들은 진행성 위암환자에서 발생한 하지 심부정맥 혈전증 및 폐동맥 혈색전증에 있어 저분자량 헤파린을 투여하며, 호전된 사례를 문헌고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제36권2호
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• pp.73-78
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• 2003

기능적 단심증에 대한 Fontan 술식은 수술 방법에 많은 변형을 거치면서 그 임상 성적 또한 향상되어 왔다. 그럼에도 불구하고 추적과정 중에 발생하는 치명적인 합병증은 장기 성적에 많은 영향을 미친다고 할수 있다. 따라서 이러한 합병증에 대한 수술적 치료가 필요하며 빈도 또한 증가하고 있다. 대상 및 방법: 1988년 4월부터 20n년 1월까지 Fontan 수술 후에 발생한 합병증에 대한 수술적 치료를 받은 16명의 환자를 대상으로 하였다. 재수술 당시 평균 연령은 8.8$\pm$5.5년이었다. Fontan수술에 적용된 술식은 심방-폐동맥 연결술 및 완전 체정맥-폐동맥 연결술이 각각 8예로 완전 체정맥-폐동맥 연결술 중 5예는 심장내 외측터널, 3예는 심장외 외측터널을 시행하였다. 이 중 천공을 추가한 경우가 5예 있었다. 재수술의 적응증은 잔존 우좌단락 6예, 폐정맥 협착 3예, 심방 조동 3예, 방실판막 폐쇄부전 2예, Fontan 유출로의 협착 1예, 단백상실성 장병증이 1예 있었다. 결과: 조기 및 만기 사망이 각각 3예 있었다. 잔존 단락이 있었던 환자에서는 2예에서 단락 부위를 일차 봉합하였고 2예에서는 체정맥과 폐정맥을 분리하기 위한 심방내 중격을 재형성하였으며 2명의 환자에서는 심장내 외측통로 및 부분 양심실 교정술로 전환하였다. 폐정맥이나 Fontan유출로의 협착이 있었던 4명의 환자에서는 3예에서 협착 부위 확장술을 시행하였고 1예에서는 좌폐 전절제술을 시행하였다. 심방 조동이 발생한 3예는 모두 심방-폐동맥 연결술에서 심장내 외측터널로 술식을 전환하였다. 2예의 방실판막 폐쇄부전 환자는 기계 판막 치환술을 시행받았으며 단백소실성 장병증이 발생한 1예는 개흉술을 통해 대동맥-폐동맥 측부 혈행을 폐쇄하였다. 4명의 환자에서 부정맥 치료의 추가적인 방법으로 냉동 절제술을 동시에 시행하였다. 결론: Fontan수술 후에 발생하는 합병증은 치료가 어렵고 상당한 유병율 및 사망률을 가지고 있다. 그러나 Fontan 생리에 대한 보다 깊은 이해와 수술 술기의 발전은 Fontan 수술 자체뿐 아니라 그 합병증의 치료 가능성을 증대시켰다. 비록 모든 환자에서 만족할 만한 결과를 얻지는 못하였으나 이러한 환자에 대한 적절한 외과적 치료로 생존환자에서 증상의 완화 및 기능적 분류의 호전을 볼 수 있었다.

• Journal of Chest Surgery
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• 제47권2호
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• pp.149-151
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• 2014

Hemangioma of the heart, presenting as a primary cardiac tumor is extremely rare; it accounts for approximately 2% of all primary resected heart tumors. In our patient, the tumor was located in the orifice of the right lower pulmonary vein. Few cases of cardiac hemangiomas have been reported to arise from the left atrial (LA) wall. Left atrial hemangiomas, especially those attached to the LA wall, may be erroneously diagnosed as myxomas. Cardiac hemangioma is a rare disease; furthermore, a tumor arising from the LA wall and misconceived as a myxoma is extremely rare. We removed a mass misdiagnosed as a myxoma; it was pathologically confirmed to be a cardiac capillary hemangioma. Therefore, we report a rare case of a cardiac hemangioma misconceived as a myxoma; the tumor was removed successfully.

• Archives of Plastic Surgery
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• 제41권6호
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• pp.728-733
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• 2014

Background Periareolar Augmentation Mastopexy is one of the most challenging operations in plastic surgery. Problems with scar quality, areolar widening, and distortion are frequent problems that interfere with a predictable result. Methods A retrospective review was performed on fifty consecutive patients who underwent a periareolar augmentation mastopexy with the interlocking approach. Of the 50 patients, 30 had both preoperative and postoperative photographs and were the basis of the study. Results The age of the patients ranged from 19 to 56 years with the average age being 39 years. The postoperative follow-up averaged 9.5 months and the implants averaged 316 mL. There were no deaths, pulmonary embolism, deep vein thrombosis, or infected implants. Four patients had complications following surgery for an overall complication rate of 13%. Two patients developed an infected Gore-Tex suture. Two of these complications were treated with revision surgery. Five patients required reoperation for an overall reoperative rate of 16% (one patient was converted to a full mastopexy). Conclusions As a result of this retrospective study, we have found the interlocking approach to periareolar augmentation/mastopexy to be a safe and reliable operation.

• Journal of Trauma and Injury
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• 제24권2호
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• pp.164-167
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• 2011

Trauma is an important risk factor for a pulmonary thromboembolism, and anticoagulation is essential to prevent deep vein thrombosis (DVT) in patients with trauma. Low-molecular-weight heparin (LMWH) is excreted in the kidney; therefore, using LMWH in patients with renal insufficiency may increase the risk of bleeding complication. The following case describes a 55-year-old traffic accident victim who had massive bleeding and underwent a laparotomy for bleeding control. The patient had acute renal failure, and enoxaparin was administered for the prophylaxis of DVT. Although the patient suffered from serious complications such as pericardial hematoma, the patient recovered without sequellae and was discharged at day 84.

• Journal of Ginseng Research
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• 제35권3호
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• pp.315-324
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• 2011

This study investigated the effect of red ginseng extract on metastasis of colon cancer cells in vitro and in vivo. Wound healing migration, cell motility, invasion, and activity, protein expression, and mRNA expression of matrix metalloproteinases (MMPs) were examined in SW480 human colon cancer cells. SW480 cells were cultured with or without $100{\mu}g/L$ PMA in the absence or presence of various concentrations (100, 200, or $300{\mu}g/mL$) of red ginseng extract. Red ginseng extract treatment caused signifi cant suppression of cell motility and invasion (p<0.05) in SW480 cells. Red ginseng extract inhibited MMP-2 and MMP-9 activity and their protein and mRNA expression in a dose-dependent manner (p<0.05) in SW480 cells. For experimental metastasis, BALB/c mice were injected intravenously with CT-26 mouse colon cancer cells in the tail vein, and were orally administered various concentrations (0, 75, 150, or 300 mg/kg body weight) of red ginseng extract for 3 weeks. Numbers of pulmonary nodules were signifi cantly decreased in mice that were fed red ginseng extract (p<0.05). Plasma MMP-2 and MMP-9 activity signifi cantly decreased in response to treatment with red ginseng extract in mice (p<0.05). These data suggest that red ginseng extract may be useful for prevention of cancer invasion and metastasis through inhibition of MMP-2 and MMP-9 pathways.

• Journal of Chest Surgery
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• 제17권4호
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• pp.804-810
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• 1984

Two hundred twenty one cases of open heart surgery were done in the Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital from July, 1981 to October, 1984. 1.There were 154 cases [73%] of congenital anomalies and 57 cases [27%] of acquired valvular heart diseases. Among the congenital cases, 128 cases were acyanotic and 26 cases were cyanotic. Among the 57 cases of acquired valvular replacement surgery, 3 cases had open heart commissurotomy, one had Kay annuloplasty. 2.The age distribution of the congenital acyanotic anomalies ranged from 5 to 32 years with mean age of 12.8 years, the congenital cyanotic anomalies from 3 to 29 years with mean age of 14.2 years and the acquired valvular diseases from 9 to 51 years with mean age of 30 years. The difference of sex distribution was no significance. 3.Three methods for debubbling process were used in our institute, in 133 cases, the vent was inserted into the left ventricular apex, in 61 cases inserted into the left atrium through right superior pulmonary vein and in 17 cases used needle aspiration only. 4.For cardioplegia, the GIK solution was infused repeatedly from 30 to 40 minutes interval and brought excellent results for myocardial protection during open heart surgery. 5.Overall mortality was 7.6%. The mortality along with each disease is 1.56% in congenital acyanotic cases, 26.9% in congenital cyanotic cases and 12.3% in acquired valvular disease.

• Journal of Chest Surgery
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• 제50권3호
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• pp.224-227
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• 2017

A 20-year-old man presented with a femur fracture and epidural hemorrhage (EDH) following a fall. One month after fracture surgery, swelling developed in both legs, and he was diagnosed as having a deep-vein thrombosis and pulmonary embolism. A retrievable inferior vena cava filter (IVCF) was inserted, because EDH is a contraindication to anticoagulants. Four months later, he complained of abdominal pain, and a computed tomography scan showed a fractured IVCF strut. After percutaneous removal failed 3 times, the IVCF was surgically removed by orthopedists using a portable image intensifier without cardiopulmonary bypass.

• 한국임상수의학회지
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• 제25권4호
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• pp.303-306
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• 2008

Unknown age, spayed female mixed dog was presented with a severe lethargy. Radiography, ultrasonography, and blood screen test were performed to make a diagnosis. There were no specific radiographic findings. On the ultrasonography, small amount of ascites was found around gallbladder and hepatic vein was dilated approximately 6.1 mm. Blood screen test revealed a severe anemia. Result of heartworm ELISA kit was positive. At necropsy, parasites were in the left atrium, right ventricles, aorta, pulmonary artery, right renal artery.