• Journal of Chest Surgery
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• 제54권5호
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• pp.412-415
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• 2021

Primary intrapulmonary thymomas (PITs) are defined as thymomas arising in intrapulmonary locations, without an associated mediastinal component. They are rare lesions, the diagnosis of which can be very difficult. We present a case of PIT in an asymptomatic 74-year-old woman in whom pulmonary nodules were found on pulmonary angiography performed for an episode of pulmonary embolism. She underwent wedge resection and the pathology report revealed a PIT. We also summarize this patient's clinicopathological features and discuss the diagnosis, pathogenesis, and treatment of PIT.

• Tuberculosis and Respiratory Diseases
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• 제47권4호
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• pp.498-506
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• 1999

연구배경 : 고립성 폐결절에 대한 접근에 있어 가장 중요한 것은 결절의 악성여부를 결정하는 것이다. 지금까지 고립성 폐결절의 악성여부에 대한 예측은 주로 방사선학적 소견에 의하여 이루어졌으나 수술 전 진단의 정확성은 보고자에 따라 차이가 있다. 수술 전 진단의 부정확은 고립성 폐결절 자체에 대한 진단의 어려움도 있지만 환자의 임상적 방사선학적 특징들을 통합적으로 고려하지 않은 점 역시 중요한 원인 중의 하나이다. 저자들은 Bayes식 접근법을 이용하여 고립성 폐결절 환자의 임상적 특징과 방사선학적 특징들을 통합적으로 고려하여 결절의 악성 확률을 구하여 진단 및 치료방법의 결정에 도움을 주고자 하였다. 대상 및 방법 : 조직학적으로 확진된 고립성 폐결절 180예를 대상으로 임상적 특징과 방사선학적 특징에 대한 Bayes식 접근법으로 결절의 악성 가능성을 후향적으로 조사하였다. 결 과 : 환자의 임상적 특징 중 연령이 증가할수록, 특히 66세 이상인 경우 likelihood ratio가 높았으며(LR 3.64), 46 pack-year 이상의 흡연력이 있는 경우 악성 가능성이 높았다(LR 8.38). 방사선학적 소견 중 결절의 크기가 클수록, 주위 조직과 경계가 불분명하고 엽상이나 극상모양의 결절이 likelihood ratio가 높았다. 결 론 : Likelihood ratio를 이용한 Bayes식 접근법을 이용하여 고립성 폐결절의 악성 확률을 예측하는 것은 특징적인 방사선학적 소견에만 의존하여 결절의 악성 가능성을 예측하는 것보다 더 정확하며, 결절의 진단이나 치료에 대한 방향을 결정을 하는데 유용한 지표로 이용될 수 있을 것으로 생각된다.

• Tuberculosis and Respiratory Diseases
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• 제87권3호
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• pp.282-291
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• 2024

The increasing incidence of incidental pulmonary nodules necessitates effective biopsy techniques for accurate diagnosis and treatment planning. This paper reviews the widely used advanced bronchoscopic techniques, such as radial endobronchial ultrasound-guided transbronchial lung biopsy, electromagnetic navigation bronchoscopy, and the cutting-edge robotic-assisted bronchoscopy. In addition, the cryobiopsy technique, which can enhance diagnostic yield by combination with conventional biopsy tools, is described for application to peripheral pulmonary lesions and mediastinal lesions, respectively.

• 한국임상수의학회지
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• 제17권1호
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• pp.129-133
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• 2000

Based on pathological findings, 5 German shepherds, revealed a mean age of 7.6 years, showing no clinical signs were diagnosed as tracheopathia osteochondroplastica(TOC). Grossly, multiple small-sizecd nodules, appeared as cobble-stones, on the cartilage rings situated in the anterior trachea and the mucosal surface of the epiglottis were showed. Numerous tiny nodules were scattered on the pleural surface of the lung. The vascular walls of the heart were irregular and coarse apearance with calcification. Histopathologically, nodules in the trachea represented an irregular expansion of the underlying tracheal ring with protrusion into the submucosa and consisted of proliferated and calcified cartilage and bone with marrow spaces containing numbers of hematopoietic cells. Pulmonary calcinosis and calcification of the vascular walls of the heart were observed. Our observations suggested that TOC arises form eccondroses and exostoses of the tracheal cartilage rings.

• Tuberculosis and Respiratory Diseases
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• 제42권3호
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• pp.419-423
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• 1995

Pulmonary histiocytosis X is an idiopathic benign disease characterized by proliferation and infiltration of lung tissue by characteristic Langerhans cells and eosinophils. Pulmonary histiocytosis X is common in young male adults, and shows variable clinical characteristics. We experienced a case of pathologically proven pulmonary histiocytosis X in a 30-year-old man who visit to our hospital due to chest discomfort and cough. The chest radiograph of our patient shows right pneumothorax and characteristic multiple thin-walled cysts on the both upper lung fields. The HRCT shows multiple thin-walled cysts, a few scattered nodules in both upper and right middle lung, and right pneumothorax.

• Tuberculosis and Respiratory Diseases
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• 제41권4호
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• pp.435-439
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• 1994

Lung cancer is the most common fatal malignant lesion in both sexes. Detection of the solitary pulmonary nodule is important because surgical series up to a third of solitary pulmonary nodules are bronchogenic carcinoma. Bronchioloalveolar cell carcinoma is a rare primary lung cancer and surgery is treatment of choice in brochioloalveolar cell carcinoma. We experinced a case of bronchioloalveolar cell carcinoma in solitary pulmonary nodule with cavitary lesion in chest CT scan, which is an uncommon finding in brochioloalveolar cell carcinoma.

• 한국동물위생학회지
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• 제40권2호
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• pp.139-142
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• 2017

A six-year-old male captive nutria (Myocastor coypus) maintained in a closed space with a small vent was found dead in his cage. Gross findings showed multifocal nodules in varying sizes, small 0.5 to large 5 cm in diameter, intermixed with normal parenchyma were scattered all over the surface of the lungs and a kidney, which the cut surface was smooth, compact and whitish in color. Microscopically, small round to oval neoplastic cells with modest to slight amounts of cytoplasm formed acinar and gland-like structures. Immunohistochemically, cells were strongly positive for E-cadherin and slightly reactive for thyroid transcription factor-1 (TTF-1). Based on those diagnostic features, the neoplasia was diagnosed as primary pulmonary adenocarcinoma (small cell type) and metastasized into the kidney. This is the first case report of malignant pulmonary tumor and its metastasis in the nutria.

• Investigative Magnetic Resonance Imaging
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• 제26권1호
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• pp.55-59
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• 2022

Sarcoidosis is a systemic disease of unknown etiology that can involve almost any organ systems, characterized by the presence of non-caseating granulomas in affected organs. Typically, the lungs and mediastinal lymph nodes are the most-affected sites, with cutaneous manifestations being the second. Subcutaneous nodules are a rare manifestation of cutaneous sarcoidosis, and it is even rarer for subcutaneous sarcoidosis to be associated with pulmonary sarcoidosis. Here, we present a case of subcutaneous sarcoidosis of the distal lower leg associated with pulmonary sarcoidosis.

• Tuberculosis and Respiratory Diseases
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• 제72권3호
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• pp.323-327
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• 2012

5-Aminosalicylate agents are the main therapeutic agents for ulcerative colitis. Balsalazide is a prodrug of 5-aminosalicylate and has fewer side effects than the other 5-aminosalicylate agents. Pulmonary complications resembling granulomatosis with polyangiitis in ulcerative colitis are extremely rare. Here, we report a patient with ulcerative colitis on balsalazide presenting respiratory symptoms and multiple pulmonary nodules from a chest radiography that was pathologically diagnosed with a limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant. To our knowledge, this is the first report of a balsalazide-induced limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant.

• Tuberculosis and Respiratory Diseases
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• 제39권1호
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• pp.79-82
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• 1992

임신성 융모상피암은 임신으로 생성되는 영양아 세포에서 기원하는 악성도가 높은 암이다. 이 암은 초기에 폐 전이를 일으키며, 폐 전이는 경계가 명확한 수개의 결절형태로 나타나는 것이 가장 흔하다. 그러나 간혹 고립성 폐전이를 일으켜 진단이 어려울 때가 있다. 저자들은 각각 일측폐의 전체, 동전양 병변, 괴사성 종양의 소견을 보인 세유형을 보고하며 융모성 질환의 발생빈도가 높은 지역에서는 여성의 고립성 폐병변의 감별에서 산부인과 병력과 융모성 성선자극 호르몬 측정의 중요성을 강조한다.