• Title/Summary/Keyword: Pulmonary lymphoma

검색결과 64건 처리시간 0.022초

폐의 원발성 비호지킨림프종의 임상상 (Clinical Feature of Primary Pulmonary Non-Hodgkin's Lymphoma)

  • 오동규;노재형;송진우;김동순
    • Tuberculosis and Respiratory Diseases
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    • 제69권5호
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    • pp.354-360
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    • 2010
  • Background: Primary non-Hodgkin's lymphoma of the lung is a rare entity. It is represented commonly as marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type. Although there have been a few reviews of this lymphoma, clinical features, radiologic findings, management and prognosis have not been well defined. Methods: We reviewed the medical records of 24 patients with primary pulmonary lymphoma between January 1995 and September 2008; all diagnoses had been confirmed based on pathology. Results: The median follow-up time was 42.3 months (range, 0.1~131.2 months). Five (20.8%) patients were asymptomatic, 17 (70.8%) patients had pulmonary symptoms, and the remaining 2 (8.3%) patients presented with constitutional symptoms. There were 16 (66.7%) patients with MALT lymphoma, 4 (16.7%) patients with diffuse large B-cell lymphoma and 4 (16.7%) patients with lymphoma that had not received a WHO classification. Radiologic findings of primary pulmonary lymphoma were diverse and multiple nodule or consolidation was the most common finding regardless of pathologic lymphoma type. PET scan was carried out in 13 (54.2%) patients and all lesions showed notable FDG uptake. MALT lymphoma showed a trend of better prognosis (3-year survival, 78.8% vs. 70.0%; 5-year survival, 78.8% vs. 52.5%; p=0.310) than non-MALT lymphoma. Conclusion: Primary non-Hodgkin's lymphoma of the lung occurs with nonspecific clinical features and radiologic findings. MALT lymphoma is the most common pathologic type of primary pulmonary lymphoma. This entity of lymphoma appears to have a good prognosis and in this study, there was a trend of better outcome than non-MALT lymphoma.

고열과 급속한 진행성 양측 폐침윤으로 폐렴이 의심되었던 T세포 임파종 (Pulmonary Involvement of T-cell type Lymphoma with Rapid, Bilateral Infiltration and High Fever Simulating Pueumonia)

  • 심태선;임채만;이상도;고윤석;김우성;김동순;김원동
    • Tuberculosis and Respiratory Diseases
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    • 제44권6호
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    • pp.1440-1446
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    • 1997
  • 저자등은 고열과 단순흉부방사선검사상 빠르게 진행하는 양측 폐의 다발성음영으로 폐렴을 의심 하였으나 조직검사상 소세포 및 대세포 혼합형의 T세포 임파종으로 확진된 1예를 경험하였기에 문헌고찰과 함께 보고 하는 바이다.

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리포이드 폐렴(Lipoid pneumonia)으로 오인된 폐에 발생한 림프절 외 변연부 B-세포 림프종 1예 (A Case of Low-grade B-cell Lymphoma of Bronchial Associated Lymphoid Tissue Mimicking Lipoid Pneumonia)

  • 조진희;양민재;유수경;서경우;김효철;신승수
    • Tuberculosis and Respiratory Diseases
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    • 제63권2호
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    • pp.194-199
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    • 2007
  • 기관에 발생한 림프절 외 변연부 B-세포 림프종(BALT lymphoma)은 폐에서 원발하는 비호지킨스 림프종의 70% 이상을 차지하지만 전체 림프종의 1% 미만을 차지할 만큼 드문 질환으로 흉부 단순 촬영에서 우연히 발견되는 경우가 많고, 예후는 비교적 양호하나 아직 확립된 치료법은 없는 상태이다. 저자들은 흉부 방사선 촬영 상 지속되는 폐침윤 소견을 주소로 내원 후 리포이드 폐렴으로 오인되어 진단과 치료가 늦어 골수 침범까지 진행된 폐에 발생한 림프절 외 변연부 B-세포 림프종을 1예를 경험하여 보고하는 바이다.

폐문 임파절 종대를 동반한 양측성 미만성 폐침윤 (Primary T-cell Lymphoma of the Lung Presenting with Bilateral Hilar Lymphadenopathies and Diffuse Pulmonary Infiltration)

  • 김보경;김치홍;문화식;송정섭;박성학
    • Tuberculosis and Respiratory Diseases
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    • 제44권1호
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    • pp.203-208
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    • 1997
  • 폐임파종은 매우 드문 질환으로 흉부 X-선상 단일 결절이나 미만성 폐침윤의 소견을 보이며 폐문 임파절 종대를 보이는 경우는 드물다. 저자들은 발열과 기침, 체중감소를 주소로 내원하여 흉부 X-선상 양측 폐문 임파절 종대와 미만성 폐침윤을 보인 환자에서 전산화단층촬영 유도하 생검상 T-세포 폐임파종으로 진단한 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

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A Case of Pulmonary MALT Lymphoma Arising from Lymphocytic Interstitial Pneumonitis

  • Park, Ki Hoon;Kwon, Soon Seog;Chung, Myung Hee;Kim, Jeana;Lee, Hee Jung;Min, Ji-Won;Kim, Yong Hyun
    • Tuberculosis and Respiratory Diseases
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    • 제73권2호
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    • pp.115-121
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    • 2012
  • Pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma is a rare disease. This disorder is considered to be a model of antigen-driven lymphoma, which is driven either by autoantigens or by chronic inflammatory conditions. Low-grade B-cell MALT lymphoma may develop from a nonneoplastic pulmonary lymphoproliferative disorder, such as lymphocytic interstitial pneumonitis (LIP). A recent estimate predicts that less than 5% of LIP patients acquire malignant, low-grade, B-cell lymphoma. In Korea, there has been no previous report of malignant low-grade, B-cell lymphoma, acquired from LIP. Here, we present the case of a patient with LIP that developed into pulmonary MALT lymphoma, six years after diagnosis.

Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Diagnosis of Lymphoma

  • Senturk, Aysegul;Babaoglu, Elif;Kilic, Hatice;Hezer, Habibe;Dogan, Hayriye Tatli;Hasanoglu, Hatice Canan;Bilaceroglu, Semra
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권10호
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    • pp.4169-4173
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    • 2014
  • Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is highly accurate in diagnosing mediastinal lymphadenopathies of lung cancer and benign disorders. However, the utility of EBUS-TBNA in the diagnosis of mediastinal lymphomas is unclear. The aim of this study was to determine the diagnostic value of EBUS-TBNA in patients with suspected lymphoma. Materials and Methods: Sixty-eight patients with isolated mediastinal lymphadenopathy and suspected of lymphoma were included in the study. EBUS-TBNA was performed on outpatients under moderate sedation. The sensitivity, specificity, negative predictive value and diagnostic accuracy of EBUS-TBNA were calculated. Results: Sixty-four patients were diagnosed by EBUS-TBNA, but four patients with non-diagnostic EBUS-TBNA required surgical procedures. Thirty-five (51.5%) patients had sarcoidosis, six (8.8%) had reactive lymphadenopathy, nine (13.3%) had tuberculosis, one (1.5%) had squamous cell carcinoma, two (2.9%) had sarcoma and fifteen (22%) had lymphoma (follicular center cell, large B-cell primary, and Hodgkin lymphomas in three, two, and ten, respectively). Of the 15 lymphoma patients, thirteen were diagnosed by EBUS and two by thoracotomy and mediastinoscopy. The sensitivity, specificity, negative predictive value, and diagnostic accuracy of EBUS-TBNA for the diagnosis of lymphoma were calculated as 86.7%, 100%, 96.4%, and 97%, respectively. Conclusions: EBUS-TBNA can be employed in the diagnosis of mediastinal lymphoma, instead of more invasive surgical procedures.

A Case of Synchronous Lung Adenocarcinoma and Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT) Type

  • Jung, Chi Young;Kwon, Kun Young
    • Tuberculosis and Respiratory Diseases
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    • 제73권1호
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    • pp.61-66
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    • 2012
  • Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type (extranodal MZL) is a distinct subgroup of non-Hodgkin's lymphoma. Pulmonary extranodal MZL is a rare entity and accounts for less than 0.5% of primary pulmonary malignancies. Only a few cases of simultaneous occurrence of lung cancer and pulmonary extranodal MZL have been reported. A 60-year-old woman was referred to our hospital with a pulmonary nodule. She was diagnosed with lung adenocarcinoma by percutaneous needle biopsy. The protrusions into the left main bronchus were found by accident while performing bronchoscopy during lung cancer evaluation. The bronchial lesions were diagnosed as extranodal MZL. Although the patient underwent surgical resection for the lung adenocarcinoma, the pulmonary extranodal MZL was left untreated; it was monitored during follow-up visits. To our knowledge, this is the first report of synchronous lung adenocarcinoma and primary extranodal MZL of the main bronchus.

Successful Management of a Life Threatening Canine Multicentric Lymphoma with Pulmonary Thromboembolism

  • Moon, Min-Young;Suh, Guk-Hyun;Choi, Hyeong-Il;Kim, Joonyoung;Kim, Ha-Jung
    • 한국임상수의학회지
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    • 제35권5호
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    • pp.218-221
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    • 2018
  • A 12-year-old, intact female Jindo was referred to our clinic due to the enlargement of all lymph nodes, as well as severe dyspnea. All palpatible lymph nodes were highly swelling and enlargement. The dog was diagnosed as end stage of multicentric lymphoma with multi-organ metastasis. In addition, the dog was diagnosed as having a pulmonary thromboembolism via computed tomography (CT) and D-dimer concentrations and prothrombin time (PT) results. This case report describes that lymphoma can be associated with pulmonary thromboembolism which is life threatening complication in dogs. The present case was managed successfully with chemotherapy and antithrombotic treatment.

종괴로 발현한 원발성 폐 혈관중심성 림프종 1예 (A Case of Primary Pulmonary Angiocentric Lymphoma Manifested as a Mass)

  • 권형주;박영우;이무열;이철호;김진관;김미영;황인석;유흥선;황순철
    • Tuberculosis and Respiratory Diseases
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    • 제46권3호
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    • pp.426-431
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    • 1999
  • 저자등은 건성기침을 주소로 내원하여 단순 흉부 방사선 촬영검사 소견상 우측 폐야에 거대종괴가 관찰되어 우하엽 절제술 및 면역조직화학 검사상 T 세포 기원의 혈관중심성 림프종으로 진단받은 1예을 경험하였기에 보고하는 바이다.

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폐에 발생한 림프절외 변연부 B-세포 림프종 1예 (A Case of Primary Pulmonary Extranodal Marginal Zone B-Cell Lymphoma of the MALT Type)

  • 한민수;강동욱;최기영;이양덕;조용선
    • Tuberculosis and Respiratory Diseases
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    • 제54권6호
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    • pp.635-639
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    • 2003
  • 폐에 발생하는 변연부 B-세포 림프종은 드문 질환으로 예후는 양호하다. 저자들은 우연히 발견된 폐종괴로 내원한 61세 남자 환자에서 폐조직생검으로 진단된 변연부 B-세포 림프종 1예를 경험하였기에 보고하는 바이다.