• Korean Journal of Veterinary Research
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• v.31 no.4
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• pp.485-490
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• 1991

A 7-year old Holstein bull showing marked thickening of left forelimb was diagnosed as pulmonary hypertrophic osteoarthropathy on the histological basis of the exostotic bone of left metacarphus. Thickening of the bone was due to apposition of excessive cancerous bone beneath the periosteum on the shaft. The lung lesion of the bull, chronic suppurative bronchopneumonia was possibly related to pathogenesis of the bone thickening.

• The Korean Journal of Nuclear Medicine
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• v.16 no.1
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• pp.73-77
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• 1982

Hypertrophic pulmonary osteoarthropathy classically consists of clubbing of the fingers and toes, periosteal new bone formation in the tubular bones, painful swelling of limbs, arthralgia and arthritis. Its pathogenesis is uncertain, but it is usually associated with malignant or inflammatory intrathoracic disease. We recently experienced a patient with the characteristic findings of this rare disease on bone scintigraphy using $^{99m}Tc-MDP$(methylene diphosphonate).