• 동의생리병리학회지
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• 제24권1호
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• pp.22-25
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• 2010

Hyangsapyeongwi-san has been used for various gastrointestinal diseases in Oriental medicine. Nevertheless, there is little known to scientific evidence for its efficacy and mechanism. This study was aimed to investigate effects of Hyangsapyeongwi-san in gastrointestinal diseases through the analysis of articles. A total of 15 articles were selected from PubMed, KTKP, and Weipu. The selected articles were analyzed according to three aspects of study types, target diseases and its efficacy, and results of clinical studies. Hyangsapyeongwi-san has positive effects in gastrointestinal disorders, such as prevent gastric mucosal injury, improve hyperacidity and dyspepsia, protect oxidative damage, and antitumor effects and enhance both cellular and humoral immunity. However, it proved insufficient to confirm its efficacy owing to lack of clinical studies of high quality. So, we need well designed studies to verify clinical efficacy of Hyangsapyeongwi-san hereafter.

• 보건의료산업학회지
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• 제12권1호
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• pp.161-171
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• 2018

Objectives : As the management philosophy of hospital social responsibility is diversified, we systematically reviewed the literature to apply ISO 26000 to the monitoring of social responsibility activities in accordance with social needs and changes. Methods : PubMed Database, NDSL and RISS were searched for articles related to CSR based on ISO 26000. The articles were classified according to aims, methods and results. Results : There is a lack of research and development of the CSR tools of hospitals, including human rights, labor practices, and consumer issues, which are parts of the seven key topics of ISO 26000. Conclusions : Based on ISO 26000 as an international standard for social responsibility activities, it is necessary to develop a measurement tool for social responsibility activities that reflects legal and institutional situations of Korean hospitals.

• Korean Journal of Acupuncture
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• 제25권3호
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• pp.167-174
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• 2008

Objective : To make comprehensive feature of previous researches on moxibustion, then build a basis of strategy for development of moxibustion-derived therapeutics. Methods : Surveyed 326 abstraction-containing literatures from total 467 of moxibustion-related papers in PubMed and 29 papers in Korea. Analysis was performed according to distribution by study subject, number by year, nation, research method, and its efficacy. Results : Moxibustion-related researches have been rapidly increased since 2001. The main contributive country for moxibustion research was China whileas few researches was done by Korea. The main subjects of moxibustion research are associated with immunity, inflammation, neurosystem, and digestive function. The most therapeutic roles of moxibustion were on pain control, modulation of immunity, anti-fatigue and anti-stress. Conclusion : This study will help Korean Oriental medical doctors to systematically review the moxibustion researches, and to develop more competitive therapeutics using moxibustion in global CAM field.

• Radiation Oncology Journal
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• 제36권2호
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• pp.85-94
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• 2018

Radiation-induced second malignancies (RISM) is one of the important late side effects of radiation therapy and has an impact on optimal treatment decision-making. Many factors contribute to the development of RISM such as age at radiation, dose and volume of irradiated area, type of irradiated organ and tissue, radiation technique and individual and family history of cancer. Exact mechanism of RISM is unknown. But nowadays, it is a growing concern in oncology because of the increased number of cancer survivors and efforts are being made to prevent or decrease the incidence of RISM. The primary search for articles was carried via Google Scholar and PubMed with keywords included 'radiation induced malignancies, second malignancies, and chemotherapy induced malignancies'. Additional papers were found through references from relevant articles. In this review article, we have discussed about the pathogenesis, factors contributing to RISM, screening and prevention strategies of RISM.

• 대한한의학회지
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• 제29권5호
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• pp.118-125
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• 2008

Objective :Ginseng is one of the most popular Oriental medicinal plants considered as a tonic worldwide. This study aimed to produce comprehensive understanding for immune-related pharmaceutical activities of Ginseng. Methods: We surveyed all literatures, 168 of immunity-focused papers with Ginseng in Pub-med, and analyzed pharmaceutical characters according to immune elements and Ginseng components. Results : The main functions of Ginseng have been associated with modulation of immunity. Whole body of Ginseng or its ingredients differently show the effects on both cellular and humoral elements of immune system. Ginseng enhances the activities of T and B lymphocytes, NK cells, macrophages and dendritic cells whileas suppresses mast cell-associated allergy and release of histamine. Conclusion : These results will provide Korean doctors or scientists an immune-related overview of Ginseng, and help them in clinical applications and developments of Korean Ginseng as a global competitive drug in world market.

• Clinical and Experimental Pediatrics
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• 제62권11호
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• pp.405-409
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• 2019

A structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug interventions for the treatment of sleep disorders in children with ASD. The Web of Science, PubMed, and Scopus databases were searched until March 2019. Study quality was assessed using the Delphi checklist. Due to the heterogeneity of the findings, a meta-analysis was not possible. Drug interventions for the treatment of sleep disorders in patients with ASD included melatonin, atomoxetine, and risperidone. Atomoxetine had no effect on sleep disorders in patients with ASD. A total of 10 studies were reviewed. Melatonin appears to be useful for the treatment of sleep problems in patients with ASD, but further studies are needed to determine the effects of other drugs.

• 보건교육건강증진학회지
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• 제30권5호
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• pp.15-26
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• 2013

Objectives: To present the bases for health education on electronic cigarettes, we analyze the present state of electronic cigarettes. Methods: We applied descriptive study, reviewing the literature from domestic and foreign electronic databases such as National Discovery for Science Leaders and PubMed. Results: Electronic cigarette has been the subject of much controversy but very little study. I reviewed and summed up the definitions, device safety, health risk, smoking cessation effects, addiction, second hand smoke, and regulations of electronic cigarettes. Conclusion: Finally,I presented the evidence-based contents and desirable direction for health education about electronic cigarettes. The results suggested that the health educators focus on the potential addiction to electronic cigarettes, instead of the cessation effects.

• 대한의료기공학회지
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• 제18권1호
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• pp.27-51
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• 2018

Objective : The purpose of this study is to examine the relationship between the brain and the pelvis. Methods : The relationship between the pelvis and the brain was searched in PubMed, and these searching studies were reviewed. Conclusions : 1. Urinary disorder is influenced by brain. 2. Brain is influenced by luteinizing hormone. 3. Pelvic floor muscles are influenced by brain. 4. Urological Chronic Pelvic Pain Syndrome(UCPPS) is influenced by brain. 5. Brain is influenced by the low intensity laser acupuncture stimulating thirteen ghost acupoints(includes CV1).

• 부모자녀건강학회지
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• 제14권1호
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• pp.28-35
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• 2011

Purpose: The aim of this study is to suggest a direction for the development of effective methods for relieving labor pain, by analyzing non-pharmacological interventions through a literature review. Methods: Collection of literature data in this study has been accomplished through theses, reports, and academic data searched on databases of the Research Information Sharing Services (Riss), PubMed, ProQuest, and the National Discovery for Science Leaders (NDSL). Results: Non-pharmacological interventions analyzed as effective in relieving labor pain, in literature published both within and outside of Korea, included: pre-delivery education, Yoga, Doula delivery care, Massage, Music therapy, Aromatherapy, Hypnosis, TENS, Sterilized water injection, and Acupuncture. Conclusion: Several different interventions have been attempted for the relief of labor pain. Since even the same intervention shows different results depending on the research method utilized, critical factors must be acknowledged that compromise the effectiveness of these methods. In addition, study of potential synergy effects of interventions that combine these various methods might also prove to be significant.

• 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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• 한국정보과학회언어공학연구회 2015년도 제27회 한글 및 한국어 정보처리 학술대회
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• pp.165-168
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• 2015

기계학습 기반의 자연어처리 모듈에서 중요한 단계 중 하나는 모듈의 입력으로 단어를 표현하는 것이다. 벡터의 사이즈가 크고, 단어 간의 유사성의 개념이 존재하지 않는 One-hot 형태와 대조적으로 유사성을 표현하기 위해서 단어를 벡터로 표현하는 단어 표현 (word representation/embedding) 생성 작업은 자연어 처리 작업의 기계학습 모델의 성능을 개선하고, 몇몇 자연어 처리 분야의 모델에서 성능 향상을 보여 주어 많은 관심을 받고 있다. 본 논문에서는 Word2Vec, CCA, 그리고 GloVe를 사용하여 106,552개의 PubMed의 바이오메디컬 논문의 요약으로 구축된 말뭉치 카테고리의 각 단어 표현 모델의 카테고리 분류 능력을 확인한다. 세부적으로 나눈 카테고리에는 질병의 이름, 질병 증상, 그리고 난소암 마커가 있다. 분류 능력을 확인하기 위해 t-SNE를 이용하여 2차원으로 단어 표현 결과를 맵핑하여 가시화 한다.