• Title/Summary/Keyword: Psa

Search Result 991, Processing Time 0.028 seconds

Association of Prostate Specific Antigen Concentration with Lifestyle Characteristics in Korean Men

  • Woo, Hee-Yeon;Park, Hyosoon;Kwon, Min-Jung;Chang, Yoosoo;Ryu, Seungho
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.11
    • /
    • pp.5695-5699
    • /
    • 2012
  • We investigated the relationships between demographics, lifestyle characteristics, and serum total prostate specific antigen (PSA) concentration and examined the population-based distribution of total PSA by age among 2,246 Korean men with a median age of 45 years. We obtained data about demographic and lifestyle characteristics based on self-reporting using a quetionnaire. We also performed physical examinations, anthropometric measurements, and biochemical measurements. The PSA concentration increased with age and there was a significant difference in total PSA concentration between the age groups of 21-60 years and >60 years. Age >60 years, height ${\geq}1.8$ m, a low frequency of alcohol consumption, and taking nutritional supplements showed a significantly increased odds ratio for increased PSA when 3.0 ng/mL was chosen as the PSA cut-off level. Smoking status, BMI, percent body fat, diabetes mellitus, fatty liver, herbal medicine use, vitamin use, and diet were not significantly associated with total PSA regardless of the cut-off level. When interpreting a single PSA test, height, alcohol consumption, and nutritional supplement use should be considered, in addition to age.

Occurrence and Epidemics of Bacterial Canker of Kiwifruit in Korea

  • Kim, Gyoung Hee;Jung, Jae Sung;Koh, Young Jin
    • The Plant Pathology Journal
    • /
    • v.33 no.4
    • /
    • pp.351-361
    • /
    • 2017
  • Bacterial canker is the largest limiting factor in the cultivation and production of kiwifruit worldwide. Typical symptoms comprise necrotic spots on leaves, canker and dieback on canes and trunks, twig wilting, and blossom necrosis. Pseudomonas syringae pv. actinidiae (Psa), which is the causal agent of kiwifruit bacterial canker, is divided into four biovars based on multilocus sequence analysis of different genes, additional PCR testing of pathogenic genes (argKtox cluster, cfl, and various effector genes), and biochemical and physiological characterization. Bacterial canker caused by Psa biovar 2 designated Psa2 was detected for the first time on the green-fleshed kiwifruit cultivar Hayward in 1988 and the yellow-fleshed kiwifruit cultivar Hort16A in 2006 in Korea. Psa biovar 3 designated Psa3, responsible for the current global pandemics of kiwifruit bacterial canker, began to appear in Korea in 2011 and caused tremendous economic losses by destroying many vines or orchards of yellow-fleshed kiwifruit cultivars in one or several growing seasons. Bacterial canker epidemics caused by both Psa2 and Psa3 are prevalent in Korea in recent years. In this review, we summarize the symptomatology, etiology, disease cycle, diagnosis, and epidemiology of kiwifruit bacterial canker in Korea.

A Study on Pretreated Paper Sludge Ash for Cement Admixture (시멘트 혼합재로의 전처리 제지애쉬 적용가능성 연구)

  • Jung, Jae-Hyun;Seo, Seong-Kwan;Chu, Yong-Sik
    • Resources Recycling
    • /
    • v.25 no.6
    • /
    • pp.58-64
    • /
    • 2016
  • Paper industry discharges many by-products and quantity of PSA (Paper sludge ash) has been increased. In this study, hydration water was added to PSA for use as cement admixture. PSA with added water was mixed with anhydrite and this mixture was used as cement substitute. Physical properties of PSA cement were changed by contents of PSA, but PSA cement containing PSA less than 10% had similar properties to those of OPC. Compressive strength of PSA cement mortar had a certain relationship with $Ca(OH)_2$ content. Compressive strength at 3 days increased, as $Ca(OH)_2$ content increased. However, the strength at 28 days increased, as $Ca(OH)_2$ content decreased.

Multi-unit Level 2 probabilistic safety assessment: Approaches and their application to a six-unit nuclear power plant site

  • Cho, Jaehyun;Han, Sang Hoon;Kim, Dong-San;Lim, Ho-Gon
    • Nuclear Engineering and Technology
    • /
    • v.50 no.8
    • /
    • pp.1234-1245
    • /
    • 2018
  • The risk of multi-unit nuclear power plants (NPPs) at a site has received considerable critical attention recently. However, current probabilistic safety assessment (PSA) procedures and computer code do not support multi-unit PSA because the traditional PSA structure is mostly used for the quantification of single-unit NPP risk. In this study, the main purpose is to develop a multi-unit Level 2 PSA method and apply it to full-power operating six-unit OPR1000. Multi-unit Level 2 PSA method consists of three steps: (1) development of single-unit Level 2 PSA; (2) extracting the mapping data from plant damage state to source term category; and (3) combining multi-unit Level 1 PSA results and mapping fractions. By applying developed multi-unit Level 2 PSA method into six-unit OPR1000, site containment failure probabilities in case of loss of ultimate heat sink, loss of off-site power, tsunami, and seismic event were quantified.

The Relationship Between Levels of Serum Testosterone and Prostate-specific Antigen in Healthy Men: An Integrative Review (성인 남성의 혈청 테스토스테론 농도와 전립선 특이항원의 관계에 대한 통합적 고찰)

  • An, Gyeong-Ju
    • Journal of Korean Biological Nursing Science
    • /
    • v.22 no.2
    • /
    • pp.71-80
    • /
    • 2020
  • Purpose: The purpose of this study was to review primary research exploring the correlations between the levels of serum testosterone and the prostate-specific antigen (PSA) in healthy men without prostate diseases. Methods: An integrative review was conducted using the Whittemore & Knafle (2005) framework. The keywords, 'testosterone & prostate-specific antigen', 'testosterone & PSA' and 'healthy men' were used to search peer-reviewed publications in six databases. Among 1,959 searched articles, eleven articles were selected after excluding articles that do not meet inclusion criteria. Literature quality was moderate (Level 3). Results: As a result of this study, it was confirmed through the nine articles that healthy adult men showed no significant correlation between the serum testosterone and the PSA. Conversely, two articles presented that the serum PSA correlate positively with the testosterone. In particular, it is inferred that the effect of the serum testosterone and the PSA secreted into a 24-hour circadian rhythm with different amplitudes and slopes would have had great influence. However, it does not consider the factors affecting the testosterone and the PSA, such as race, liver disease, and BMI, so there is insufficient empirical data to clearly explain the relationship between the testosterone and the PSA. Conclusion: The correlation between the serum testosterone and the PSA in healthy adult men is insignificant in relation to the circadian rhythm of the testosterone and the PSA secretion. It is that a large-scale study including various influencing factors using new biochemical indicators such as pro PSA be conducted in the future.

Prostate-Specific Antigen Levels in Relation to Background Factors: Are there Links to Endocrine Disrupting Chemicals and AhR Expression?

  • Bidgoli, Sepideh Arbabi;Jabari, Nasim;Zavarhei, Mansour Djamali
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.15
    • /
    • pp.6121-6125
    • /
    • 2014
  • Background: Prostate-specific antigen (PSA) is a potential biomarker for early detection of prostate cancer (PCa) but its level is known to be affected by many background factors and roles of ubiquitous toxicants have not been determined. Endocrine disrupting chemicals (EDCs) are ubiquitous reproductive toxicants used in consumer products, which promote tumor formation in some reproductive model systems by binding to AhR, but human data on its expression in prostate cancer as well as its association with PSA levels are not clear. This study aimed to evaluate the expression levels of AhR and its association with serological levels of PSA and to detect possible effects of background factors and EDC exposure history on PSA levels in PCa cases. Materials and Methods: A cross-sectional study was conducted on the tissue levels of AhR and serum levels of PSA in 53 PCa cases from 2008-2011 and associations between each and background and lifestyle related factors were determined. Results: Although the AhR was overexpressed in PCa and correlated with the age of patients, it did not correlate with PSA levels.Of nutritional factors, increased intake of polysaturated fats and fish in the routine regimen of PCa cases increased the PSA levels significantly. Conclusions: AhR overexpression in PCa pontws to roles of EDCs in PCa but without any direct association with PSA levels. However, PSA levels are affected by exposure to possible toxicants in foods whichneed to be assessed as possible risk factors of PCa in future studies.

Comparison of PSA and VSA processes for air separation (공기 분리를 위한 O2 PSA (Pressure Swing Adsorption)공정과 VSA (Vacuum Swing Adsorption) 공정의 설게 및 성능 비교)

  • Lee, Sang Jin;Ahn, Hyungwoong;Jee, Jeung-Geun;Kim, Min-Bae;Moon, Jong-Ho;Bae, Yoon-Sang;Lee, Chang-Ha
    • Clean Technology
    • /
    • v.10 no.2
    • /
    • pp.101-109
    • /
    • 2004
  • PSA and VSA processes have been used broadly to produce oxygen from ambient air in midium- or small-sized plants. PSA and VSA processes are the separation methods which use difference of amount adsorbed as pressure is changed periodically, but they have the differences in pressurization and regeneration. In this study, the performance of 6-step PSA process was compared with that of 5-step VSA process with respect to purity and recovery. In addition, the effects of each step (pressurization step, adsorption step, and pressure equalization step) on purity and recovery were investigated. As a result, the VSA process using zeolite 10X showed better performance than the zeolite 5A PSA and zeolite 13X VSA process in comparison with purity, recovery and productivity. And it was enough to apply the vacuum pressure of 200 torr for the VSA, which produced over 90% oxygen with 70% recovery.

  • PDF

Head to Head Comparison of the Chun Nomogram, Percentage Free PSA and Primary Circulating Prostate Cells to Predict the Presence of Prostate Cancer at Repeat Biopsy

  • Murray, Nigel P;Reyes, Eduardo;Orellana, Nelson;Fuentealba, Cynthia;Jacob, Omar
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.6
    • /
    • pp.2941-2946
    • /
    • 2016
  • Background: The limitations of total serum PSA values remain problematic, especially after an initial negative prostate biopsy. In this prospective study of Chilean men with a continued suspicion of prostate cancer due to a persistently elevated total serum PSA, abnormal digital rectal examination and initial negative prostate biopsy were compared with the use of the on-line Chun nomagram, detection of primary malignant circulating prostate cells (CPCs) and free percent PSA to predict a positive second prostate biopsy. We hypothesized that men negative for circulating prostate cells have a small risk of clinically significant prostate cancer and thus may be conservatively observed. Men positive for circulating prostate cells should undergo biopsy to confirm prostate cancer. Materials and Methods: Consecutive men with a continued suspicion of prostate cancer underwent 12 core TRUS prostate biopsy; age, total serum PSA and percentage free PSA and Chun nomagram scores were registered. Immediately before biopsy an 8ml blood simple was taken to detect primary mCPCs. Mononuclear cells were obtained by differential gel centrifugation and identified using double immunostaining with anti-PSA and anti-P504S. Biopsies were classifed as cancer/no-cancer, mCPC detecton test as negative/positive and the total number of cells/8ml registered. Areas under the curve (AUC) for percentage free PSA, Chun score and CPCs were calculated and compared. Diagnostic yields were calculated with reference to the number of possible biopsies that could be avoided and the number of clinically significant cancers that would be missed. Results: A total of 164 men underwent a second biopsy; 41 (25%) had cancer; the AUCs were 0.65 for free PSA, 0.76 for the Chun score and 0.87 for CPC detection, the last having a significantly superior prediction value (p=0.01). Using cut off values of free PSA <10%, Chun score >50% and ${\geq}1$ CPC detected, CPC detection had a higher diagnostic yield. Some 4/41 cancers complied with the criteria for active surveillance, free PSA and the Chun score missed a higher number of significant cancers when compared with CPC detection. Conclusions: Primary CPC detection outperformed the use of free PSA and the Chun nomagram in predicting clinically significant prostate cancer at repeat prostate biopsy.

Analysis of pitch static attitude (열 보조 자기기록용 서스펜션의 PSA 에 대한 분석)

  • Park, Kyoung-Su;Kim, Ki-Hoon;Lee, Yong-Hyun;Kim, Seok-Wan;Lee, Sang-Jic;Park, No-Cheol;Park, Young-Pil
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2009.10a
    • /
    • pp.519-523
    • /
    • 2009
  • This paper presents the analysis of pitch static attitude (PSA) in thermally assisted magnetic recording (TAMR) suspension. The TAMR suspension using an optical fiber has high stiffness such as vertical, pitch and roll. Therefore, P-torque is greatly increased by the optical fiber. Also, flying height (FH) of the slider with TAMR suspension can be largely changed by PSA. In this paper, we focus on the FH by PSA of TAMR suspension. The FH is investigated using various PSA and proper PSA is proposed.

  • PDF

Rigorous dynamic simulation and determination of initial operating conditions for two-bed PSA processes (두 탑 PSA공정의 상세 동적모사 및 초기운전조건 결정)

  • Hwang, Deok-Jae;Moon, Il
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 1997.10a
    • /
    • pp.1520-1523
    • /
    • 1997
  • A rigorous dynamic simulation was performed in binary gas mixture H$_{2}$/CO (70:30 vol.%) to determinate start-up operating conditions of PSA(Pressure Swing Adsorption) processes. The rigorous dynamic model for the PSA process contains an Ergun equation for expressing the pressure drop in a bed, and valve equations to compute the boundary pressure change of the bed. As the result of the continuous dynamic simulation of 100 operating cyles in various initial conditions, the unsteady-state appeared in the early period and the cyclic steady-state came out about 20th cycle in feed condition and vaccum condition, and 30th cycle in pure H$_{2}$ condition. As time goes by valve equations made change the pressure at each end of the bed in ressurization, countercurrunt-depressurization and pressure equalization steps. The H$_{2}$ purity and the recovery is 99.99% and 86.73% respectively, which is slightly higher than the experimental data. Main contributiion of this study includes supplying fundamental technologies of handling combined variables PSA processes by developing rigorous models.

  • PDF