• Journal of Korean society of Dental Hygiene
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• v.13 no.6
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• pp.987-993
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• 2013

Objectives : The aim of the study is to offer basic data that help to reduce dental fear by measuring adult dental fear level with DFS scale. Methods : The subjects were 300 persons including college students in W University and their parents in Jeollabuk-do Province. Data were collected by convenience sampling from May 1 to May 30, 2013. Results : 1. Dental clinic visit provoked pain in 99 people(47.4%). Oral examination and preventive treatment evoked pain in 13 people(6.2%). 2. Women tended to feel much pain than men. Both women and men felt the thrilling fear when a needle pricks the flesh. 3. Respondents having dental caries, gum bleeding, halitosis, shaking tooth, and painful tooth had a higher dental fear level. 4. The direct pain experience(p<0.001) had the greatest influence. The next influencing factor was the insufficient anesthesia(p<0.05). 5. The explanatory power that the pain experience has influence upon dental fear is $R^2$=0.151. Conclusions : The direct pain experience and the insufficient anesthesia experience have the great influence upon patients' dental fear level. Anesthetics and analgesics can be considered as one of the positive methods for pain control.

• Preventive Nutrition and Food Science
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• v.22 no.2
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• pp.144-148
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• 2017

Sulfites are used as food preservatives and excessive sulfite might disturb the body systems including the brain. Curcumin shows protective effects on the nervous system toxicity. The present study aimed to evaluate the protective role of curcumin in sulfite-induced anxiety in rats. Male rats were divided into five groups. The rats in groups I to V received distilled water (vehicle of sulfite, 1 mL/d), olive oil (vehicle of curcumin, 1 mL/d), curcumin (100 mg/kg/d), sulfite (25 mg/kg/d), and sulfite+curcumin, respectively, by daily gastric gavage for 8 weeks. At the end of 8 weeks the rats were tested in the elevated plus-maze for anxiety. The results showed that concomitant treatment of curcumin during sulfite consumption prevented the reduction of the time spent in the open arm and entrance to the open arm (the indexes of anxiety). Besides, an increase was found in motor activity of the rats in the sulfite+curcumin group compared to the sulfite-treated animals. Exposure of sulfite in rats can induce anxiety, and curcumin can act as an anti-anxiety agent.

• Nutritional Sciences
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• v.9 no.3
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• pp.152-158
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• 2006

Helicobacter pylori (H. pylori) infection rapidly stimulated either COX-2 or 5-LOX and released arachidonic acid metabolites that have been considered as pivotal mediators in H. pylori-induced inflammatory responses. To determine whether red ginseng extract (RGE) can suppress the biosynthesis of 5(S)-hydroxyeicosatetraenoic acids (HETE), a precursor metabolite of leukotrienes B4 (LTB4) in H. pylori-provoked inflammatory responses in gastric epithelial cells, the biosynthesis of monohydroxy fatty acids was measured using radioactive arachidonic acid and validated by RP-HPLC using non-radioactive AA as substrate in AGS cells cocultured with H. pylori (ATCC 43504) with or without pretreatment of RGE. Among three known major HETEs, H. pylori infection specifically induced the biosynthesis of $^{14}C-5(S)-HETE$ rather than the complex of $^{14}C-15S-/^{14}C-12(S)-HETE$ from $^{14}C-AA$, concomitantly obtained by HPLC(p<0.01). RGE, 1 to $100{\mu}g/ml$, selectively suppressed H. pylori-stimulated $^{14}C-5(S)-HETE$ production implying the attenuation of 5-lipoxygenase activity, of which was similar to known LOX inhibitor NDGA $(10{\mu}M)$ (p<0.01). However, the amount of 5(S)-HETE was significantly reduced by higher dose of RGE $(100{\mu}g/ml)$ (p<0.05). These results indicated that LOX pathway might be one of principle pathogenic mechanisms of H. pylori and red ginseng could be a nutraceutical against H. pylori infection through inhibiting action of LOX activity.

• The Journal of Pediatrics of Korean Medicine
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• v.6 no.1
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• pp.1-14
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• 1992

Experimental studies were done to research the clinical effects of Juguieum and Juguieum-gamibang(Juguieum with Lonicerae Flos and Forsythiae Fructus added) on the Antiallergic effect. The results obtained as follows; 1. In the effects of Jugieum and Jugieum-gamibang on vascular permeability responses to intradermal histamine, Juguieum group revealed none significant effect, but Jugieum-gamibang group revealed significant effect. 2. In the effects of Juguieum and Juguieum-gamibang on vascular permeability responses to intradermal serotonin, Juguieum and Juguieum-gamibang groups revealed significant effect. 3. In the 48hrs homologous passive cutaneous amaphylaxis provoked by the IgE-like antibody against egg albumin, Juguieum and Juguieum-gamibang groups revealed significant effect. 4. In the delayed type hypersensitivity responses to Picryl Chloride, Juguieum and Juguieum-gamibang groups revealed significant effect. 5. In the delayed type hypersensitivity responses to SRBC, Juguieum group revealed significant effect, but Jugieum-gamibang group revealed none significant effect. According to above-stated results, Juguieum and Juguieum-gamibang are concluded to be effective as anti-allergic regimen and recommended to be used for the treatment of type I and type IV allergic disease.

• The Korean Journal of Zoology
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• v.33 no.3
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• pp.247-254
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• 1990

Chicken monocular head and eye optokinetic nystagmus (OKN) were observed by coil recordings after intravitreal administration of GABA antagonists (picrotoxin and bicuculline) into the opened and closed eye. Before injection of drugs the chicken displayed an OKN for T-N stimulation being more efficient in evoking this visuomotor reflex than for N-T stimulation. The injection of GABA antagonist into the opened eye provoked a decrease or disappearance of the head and eye OKN. On the other hand, the injection of GABA antagonist into the closed eye, the head and eye OKN augmented. Thus, GABA antagonist abolished the directional asymmetry of the head and eye OKN, indicating the involvement of GABAergic mechanisms in the inhibition of the N-T component of the monocular OKN.

• The Korean Journal of Zoology
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• v.33 no.2
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• pp.133-140
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• 1990

In monocular vision, bead and eye optokinetic nystagmus (OKN) display directionnal asymmetry, in lower vertebrates such as chickens, T-N stimulation being more efficient in evoking this visuomotor reflex than N-T stimulation. The N-T component of monocular OKN is significantly weaker in chickens. Coil recordings and observation showed that in adult chickens, prolonged monocular visual deprivation by unilateral eyelid suture provoked significant and progressive increase of the N-T component in chickens. This plasticity phenomenon involved the eye and head OKN in chickens. The administration of THIP, a GABA agonist, abolished reversibly the increase of the N-T component in chickens. This fact suggests that the GABAergic system could be involved in determining this plasticity phenomenon observed in adult lower vertebrates.

• The Korean Journal of Zoology
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• v.27 no.2
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• pp.93-102
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• 1984

Xenopus laevis eggs were de-jellied and manually manipulated to remove their vitelline membranes. They were then positioned in a variety of orientations re. gravity. That is the future ventral side was located upwards (opposed gravity) or downwards (faced gravity). Development through the tailbud stage was observed and the frequency of double axes formation recorded. Orientation of the egg re. its natural polarity was not an important factor in generating double axes. Its physical structure (flattened re. spherical), however, appeared to be important in determining the frequency of twinning. These observations give insights into the mechsnism of polarity establishment in anuran eggs, and provide methods which should be useful for studies on primary embryonic induction.

• Archives of Pharmacal Research
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• v.29 no.6
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• pp.503-507
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• 2006

Flavonoids are known as natural anti-inflammatory agents. In this investigation, an anti-inflammatory potential of new topical preparation (SK Ato $Formula^{\circledR}$) containing flavonoid mixtures from Scutellaria baicalensis Georgi roots and Ginkgo biloba L. leaves with an extract of Gentiana scabra Bunge roots was evaluated in an animal model of chronic skin inflammation. Multiple 12-O-tetradecanoylphorbol-13-acetate treatments for 7 consecutive days on ICR mouse ear provoked a chronic type of skin inflammation: dermal edema, epidermal hyperplasia and infiltration of inflammatory cells. When topically applied in this model, this row formulation $(5-20\;{\mu}L/ear/treatment)$ reduced these responses. Furthermore, it inhibited prostaglandin $E_2$ generation (17.1-33.3%) and suppressed the expression of proinflammatory genes, cyclooxygenase-2 and $interleulin-1{\beta}$ in the skin lesion. Although the potency of inhibition was lower than that of prednisolone, all these results suggest that Ato $Formula^{\circledR}$ may be beneficial for treating chronic skin inflammatory disorders such as atopic dermatitis.

• KIEAE Journal
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• v.7 no.5
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• pp.47-52
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• 2007

The high-rise apartment buildings have been constructed in large quantities to provide housing and used to be the popular residential types in Korea. However, it results that a number of problems are provoked such as the deteriorate of comfort and lack of sunshine access. Based on the judicial precedents, the sunshine access right should be guaranteed to enjoy uninterrupted sunlight for more than two hours continually between 9 am. and 3 pm or for more than four hours between 8 am and 4 pm in the winter solstice. The computer simulations are very strong tools to judge that the sunshine access right is infringed or not. This study aims to evaluate the efficiency of two computer simulation programs such as 3Dmax and Lightscape programs broadly used in field areas. For the study, the three dimensional computer models are suggested, and the simulations are performed on the 30 minutes intervals. Also, the simulation results are compared by the results of scaled model experiments.

• Journal of the Korean Home Economics Association
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• v.37 no.11
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• pp.97-113
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• 1999

The purpose of this is to analyze the perception of sex image by feministic fashion based on the theory of feminism, which has been developed since the 1960’s. Feministic fashion is divided 8 style and analyzed. For this study, surveying photo of feministic fashion and making out questionnaires. The data was collected from 391 university student(184 male, 207 female) living in Taegu and Kyoungpok and is analyzed by factor analysis, t-test. The result are as follows: 1. The Tendency of perceiving Feministic Fashion’s Sexual Image Male had more positive view on the sexual image of see-through and Body-conscious styles than female. And male showed more negative view on the sexual image of lingerie, punk, madonna or disorganized style. There was no significant difference between male and female in their opinion on the sex appeal of fashion that exposed some physical part. Concerning the sexual image of unisex mode, both male and female had an idea that it had nothing to do with sex appeal. Regarding the preference for sex-expressive fashion, they favored see-through and Body-conscious styles most. 2. In relation to clothing behavior toward sex-expressive fashion, both male and female generally revealed a negative view on fashion that exposed physical part and provoked an impression of keen sex appeal. 3. Sexual perception degree about the body, in physical exposure, that physical part from which they felt sex appeal most was the breast. What they most wanted to emphasize was the breast, too. As a physical part that caused their rejection symptom and made them feel hatred both and female pointed out the hips.