• Journal of Physiology & Pathology in Korean Medicine
• /
• v.18 no.3
• /
• pp.747-753
• /
• 2004

Effects of methanolic extract from Adenophorae Radix (AR) on melanogenesis were investigated in mouse melanoma B16F10 cells. The methanol extract of AR was partitioned into Hexane, Ethyl acetate (EA), Butanol, H₂O, and exogenously added to the culture medium for 72 hours at the concentration of 10, 50, 100 and 200 ㎍/㎖. Of the four partitions, Hexane and EA partion of AR reduced tyrosinase activity, which is the key enzyme for a melanogenesis, as well as melanin contents. But the EA partition was less toxic for B16F10 cells and has more efficient melanin-reducing effect than the former. In addition, the EA partition dramatically lightened the color of cell pellet and significantly decreased the level of tyrosinase protein expression. In these results, EA partition of AR reduced melanin synthesis of B16F10 mouse melanoma cells by down regulating the tyrosinase activity and tyrosinase protein expression. Therefore, it is anticipated that AR is a candidate for an efficient whitening agent which supresses melanogenesis.

• Human Ecology Research
• /
• v.52 no.1
• /
• pp.63-73
• /
• 2014

The purpose of this study is to investigate early childhood student teachers' practicum anxiety on the basis of the teacher's image and self-efficacy during their practicum. The participants of this study were 499 student teachers who were enrolled in the department of early childhood education in a college or a university and had completed the practicum in Daejeon metropolitan city or the Chungcheong area. The instruments for this study were the Teacher's Image Scale, Practicum Anxiety Scale, Self-efficacy Scale, and a questionnaire for socio-demographic variables. The collected data were analyzed by using a t -test, F test, Pearson's partial correlation, and multiple regression with SPSS software (version 20.0). The results were as follows: First, the student teachers expressed higher practicum anxiety in a provincial area than in metropolitan city, and their self-efficacy was higher in public kindergarten than in private kindergarten. Further, the highest level of the teacher's image was obtained in the case of student teachers who enrolled in a 2- or 3-year college program and completed the practicum in the metropolitan city. Second, there was a significant negative correlation between the sum of student teachers' practicum anxiety and their professional skills of teacher's image as well as significant correlations between the sum of student teachers' practicum anxiety and their self-efficacy, except self-control efficacy. Finally, the student teachers' practicum anxiety was found to be 17.5%-24.4% and was explained the most by the confidence of self-efficacy.

• Korean Journal of Agricultural Science
• /
• v.43 no.4
• /
• pp.688-703
• /
• 2016

The 6th industrialization, which is the policy strategy to combine the 1st, 2nd, 3rd agro-food industries in order to create synergy effects, is one of the most important policy strategies for the Korean government. Local governments as well as the central government, especially the Ministry of Agriculture, Food and Rural Affairs, have introduced various specific programs for the 6th industrialization. Among them, the 6th industry antenna shops located in Cheonan and Daejeon which were introduced by the Chungcheongnam-do Provincial Government to offer a better market place for 6th industry producers. However, few studies have been conducted to evaluate the performance of 6th industry antenna shops. The purpose of this paper is to analyze consumers' satisfaction of 6th industry antenna shops through survey and econometric modeling and to present some implications of the better operation of the 6th industry antenna shops. The results of the studies in this paper present some of the following findings: first, the overall level of satisfaction towards 6th industry antenna shops is high but consumers still claim some problems. Second, products which are sold at 6th industry antenna shops have important problems, including high prices and deficient product variety. Third, if these problems were fixed, the operation of 6th industry antenna shops would be successful and contribute to the development of 6th industrialization in Korea.

• Journal of Environmental Health Sciences
• /
• v.43 no.1
• /
• pp.55-63
• /
• 2017

Objectives: This study estimated the emission quantity of benzo(a)pyrene(BaP) produced by fuel combustion in the Seosan area, and analyzed the uncertainty regarding the emissions. Methods: It was based on data from a national agency and from public institutions. Emissions were estimated by using national-level guidelines. The total estimated emissions were analyzed by performing Monte Carlo analysis. Results: The full emission quantity of BaP which was discharged by fuel combustion in the Seosan area stood at 1,194.79 g/yr. The point source emissions came to 184.16 g/yr (95% CI; 158.40-209.39). The line source emissions reached 315.33 g/yr (95% CI; 284.99-344.03). The area source emissions accounted for 695.31 g/yr (95% CI; 605.10-793.88). Chemical and compound manufacturing was the highest with 639.13 g/yr (95% CI; 542.95-728.24) in terms of emissions and oil refinery emissions were high with 153.10 g/yr (95% CI; 129.19~177.46). It was found in the Seosan area that the major source of BaP is the manufacturing of chemicals and chemical products. Conclusion: The emission quantity of BaP which was discharged by the fuel combustion in Seosan area reached 1,194.79 g/yr. Research needs to be continued for the definite estimation of emission of BaP henceforth.

• Journal of the Korea Concrete Institute
• /
• v.16 no.5 s.83
• /
• pp.697-707
• /
• 2004

Most bridge piers were practically designed and constructed with lap spliced longitudinal reinforcing steels before the 1992 seismic design provisions of Korea Bridge Design Specification were implemented. It has been known that lap splice of longitudinal reinforcement in the plastic hinge region is not desirable for seismic performance of RC bridge piers. The objective of this research is to evaluate the seismic performance of existing circular reinforced concrete bridge piers by the Quasi-static test and to propose the need of seismic retrofit of existing bridge piers through the damage level. Test specimens were nonseismically designed with the aspect ratio 4.0 which could induce the flexural failure mode. It was confirmed from this experiment that significant reduction of seismic performance was observed for test specimens with lap spliced longitudinal reinforcing steels. Pertinent seismic retrofit was determined to be needed for existing RC bridge piers with the lap-spliced of $50\%$ longitudinal reinforcing steels.

• Journal of Korean Clinical Health Science
• /
• v.2 no.2
• /
• pp.126-132
• /
• 2014

Purpose. Because traditional statistics approach had limitations in learning future forecasting and major factors causing occupational injuries in each industry, this paper develops a model forecasting and evaluating occupational injury rate by using a system dynamics model through the analysis of the industry injury statistics and the project for industry injury prevention. Method. The model of this paper consists of 12 total models such as a model of employees, of industrial disaster victims, of injury rate, etc.; In the analysis of firm size, it is classified and developed according to 12 groups on the basis of the number of employees, and in the analysis of industrial classification, it is done according to 10 total business fields such as manufacturing business, construction one, etc. Results. This paper suggests the methodology which forecasts industry injury rate by business field and size on the basis of developed model, and evaluates an industry injury prevention project from various angles. Conclusions. This paper deduced problem through the analysis of an industry injury by business fields and a comparative analysis of foreign cases, and analyzed to affect industry injury prevention by industry. And it also analyzed actual condition of industry injury, and did a difference in the level of safety consciousness according to the general characteristics of workers and occupational safety and health education related characteristics. In result, this paper suggests that analyzing occupational injury related factors, a safety budgetary allocation, and industry injury related factors can reduce illness costs such as employees' injury and medical care, and also assist cost for a disability.

• Journal of Korean Clinical Health Science
• /
• v.1 no.3
• /
• pp.49-61
• /
• 2013

Purpose. The purpose of this study is to analyze difference in quality of life related to health according to our country's social stratification. Methods. This study had analytical subjects as 7,992 adults(4,557 men, 3,435 women), who are included in a variable by social stratification among 15,691 people in the age group of 20~69 years old as examinees, based on the 4th Korea National Health and Nutrition Examination Survey. Results. This study obtained the following results. First, seeing the score of health-related life quality by social stratification, namely, the distribution of EQ-5D index, the new middle class(class II) was the highest(men with 0.966 point, women with 0.955 point). The agricultural self-employed class(class V) was indicated to be the lowest(men with 0.918 point, women with 0.866 point). In general, the more belonging to low social stratification led to having shown the lower aspect in EQ-5D index value. Second, as for the results of the hierarchical regression analysis, the factors of contributing to difference by social stratification in health-related quality of life were chronic disease, job stress, education, and income level in both men and women. The health behavior was grasped to be a factor of contributing only to women. Conclusions. To reduce difference in health-related quality of life according to social stratification in the future, the continuous investment is needed for supporting socially high-quality education and economic stability. The sphere of health will need to be given priority to the prevention of chronic disease and the development in effective management policy for the lower classes.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.30 no.5
• /
• pp.207-216
• /
• 2018

This research compared and analyzed safety ratio of slope with Talren97 and SoilWorks based on limit equilibrium analysis and Midas GTS based on finite element analysis. For the analysis variables, there are slope height, berm condition, soil parameter, groundwater level, slope inclination. All of slope stability analysis were performed by dividing into dry season and rainy season. As the result of the analysis of Talren97 and SoilWorks based on same theory, safety ratio of slope shows same value, so there was no difference between the programs. In comparison with limit equilibrium analysis, the result of finite element analysis showed somewhat high ratio of safety and it was higher by about 2.4% averagely. The difference between the result of limit equilibrium analysis and that of finite element analysis is in the range which can ignored in practical work.

• Development and Reproduction
• /
• v.16 no.4
• /
• pp.279-287
• /
• 2012

We investigated the changes in plasma sex steroid hormones, testosterone (T), estradiol-$17{\beta}$ ($E_2$), 17,$20{\beta}$-dihydroxy-4-pregnen-3-one ($17{\alpha}20{\beta}P$), 11-ketotestosterone (11KT) and cortisol levels from ribbed gunnel, Dictyosoma burgeri in associated with annual reproductive cycle. The gonadosomatic index (GSI) of females increased from November, peaked in February and decreased rapidly from March. The GSI of males also increased from November, peaked in January and then decreased gradually. In females, $E_2$ levels increased and remained high from December to February. The levels of T showed a similar tendency and correlated ($r_s$=0.898, p<0.01) with $E_2$ levels. The levels of $17{\alpha}20{\beta}P$ increased rapidly in February ($4.78{\pm}1.01ng/ml$) and peaked in July ($5.08{\pm}0.65ng/ml$). Cortisol level was peaked in March and correlated with $17{\alpha}20{\beta}P$ levels ($r_s$=0.696, p<0.01). In males, the levels of T was peaked in January and then decreased rapidly. The levels of 11KT were remained high from October to January. On the other hand, the levels of $17{\alpha}20{\beta}P$ fluctuated during reproductive cycle. These results suggest that plasma sex steroids in ribbed gunnels have annual periodicity, and that cortisol may involve in maturation of females.

• Korean Journal of Plant Tissue Culture
• /
• v.21 no.4
• /
• pp.193-200
• /
• 1994

The effects of sucrose concentration and nitrogen source on shoot growth and in vitro formation of garlic (Allium sativum L. cv Seosan) bulblet were investigated in order to systematize propagation of high quality garlic through a shoot apical meristem culture. Shoot differentiation was not affected by sucrose concentration and nitrogen source, but plantlets which contain medium of NH$_4$- N or NH$_4$ + NO$_3$ were vigorous and healthy in .appearance. Shoot growth was vigorous in changeing of nitrogen source. The best quality of in vitro bulblets was obtained in culture on the medium containing 8% sucrose and NH$_4$ - N, and the formation of bulblet was more effective when plantlets were subjected to cold treatment before use. NH$_4$-N was a major factor for shoot growth and bulblet development, but NO$_3$-N was not and suppressed $K^{+}$absorption. The level of ethylene production was not affected by different nitrogen sources, however this production was enhanced in medium containing a higher concentration of sucrose.e.