• 한국식품영양학회지
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• 제29권2호
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• pp.290-299
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• 2016

This study was conducted to determine the association between dietary calcium intake and biomarkers related to lipid and glucose metabolism and inflammation in Korean patients with type 2 diabetes. Seventy-five subjects (41 males, 34 females) were recruited from a group of patients who had visited the department of endocrine medicine. Data on anthropometric characteristics, clinical indices such as hemoglobin A1c and C-reactive protein (CRP), and dietary nutrient intakes were collected. Subjects were divided into three groups on the basis of their calcium intake [< EAR (below estimated average requirement), EAR-RNI (between EAR and recommended nutrient intake), > RNI (above RNI)]. Average calcium intake of < EAR, EAR-RNI, > RNI groups were $462.7{\pm}18.7$, $649.7{\pm}12.8$, and $895.7{\pm}21.7mg$, respectively. Energy intake was not different among groups but intakes of protein, total and saturated fatty acids were significantly higher in > RNI group than < EAR group. Analysis of covariance revealed that HDL cholesterol level was significantly higher in EAR-RNI group, as compared to < EAR group after adjustment with confounders such as age, sex, BMI and energy intake (p < 0.05). Levels of CRP and homeostasis model assessment 2-insulin resistance (HOMA2-IR) were significantly lower in EAR-RNI group. Total cholesterol level was higher in EAR-RNI and > RNI groups, although within the normal range. Our results suggest that dietary calcium intake may influence the levels of HDL-cholesterol, CRP and HOMA2-IR and subsequently, help management/treatment of type 2 diabetes patients.

• Animal Bioscience
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• 제34권5호
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• pp.886-894
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• 2021

Objective: An experiment was conducted to study the effect of graded concentration of digestible lysine (dLys) on performance of layers fed diets containing sub-optimal level of protein. Methods: Five diets were formulated to contain graded concentrations of dLys (0.700%, 0.665%, 0.630%, 0.593%, and 0.563%), but similar levels of crude protein (15% CP), energy (10.25 MJ ME/kg) and other nutrients. A total of 3,520 hens (26 wk of age) with mean body weight of 1,215+12.65 g were randomly divided into 40 replicate groups of 88 birds in each and housed in an open sided colony cage house. Each diet was offered ad libitum to eight replicates from 27 to 74 wk of age. The performance was compiled at every 28 d and the data for each parameter were grouped into three phases, that is early laying phase (27 to 38 wk), mid laying phase (39 to 58 wk), and late laying phase (59 to 74 wk of age) for statistical analysis. Results: Egg production, egg mass and feed efficiency (feed required to produce an egg) were significantly improved by the dLys level during the early and mid laying phases but not during the late phase. Whereas feed intake was significantly reduced by dLys concentration during mid and late laying phases but not during early laying phase. The egg weight was not affected by dLys concentration in any of the three phases. Conclusion: Based on best fitted statistical models, dietary requirements of dLys worked out to be 0.685%, 0.640%, and 0.586% during early phase, mid phase, and late egg laying phase, respectively. The calculated requirement of dLys for the respective production phases are 727 mg/b/d during the early and mid laying phases and 684 mg/b/d during the late laying phase in diets containing 15% CP.

• Journal of Nutrition and Health
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• 제18권1호
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• pp.46-54
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• 1985

Three types of infant food were experimentally prepared based on the average caloric requirement for, Koreans : Formula A, with 1/3 RDA for 4-6 month, formula B, with 1/2 RDA for 7-9 month, and formula C, with 2/3 RDA for 10-12 month old infants. Into each formula was added approximately 50% of rice. Analysis of the nutritive values on these formula showed no deviance Com the expected values in case of general nutrients while the percent of essential amino acids in protein was muck higher except methionine. Since iron content was found to be below the half of except values, a sufficient amount of iron as required in RDA should be additionally supplied, for example, in iron drops. The infant preference test on each formula showed much favorable acceptability : 50% of them responded as moderate, 33.3% as favorable, 12.5% as disliking, and 4.2% as disgusting. The test also showed no noticeable change in both feces and appetite.

• 미생물학회지
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• 제25권2호
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• pp.129-136
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• 1987

영남작물시험장에서 질소비료 공급없이 재배합 40종의 수도품종으로부터 출수기전의 수도근권의 질소고정력을 in situacetylene 환원력 측정방법으로 시험한 결과 Azospirillum 균의 무질소 malate 배지에서 얻은 균주와 상관관계를 보였다. 이 중 질소고정력이 높은 6종의 Azospirillum을 분리 동정한 결고 5종은 A. lipoferum, 1종은 A. brasilense임을 확인한 후 이들 6종의 Azospirillum들의 당이용성, biotin 요구성, 항생제저항성, auxin 생산성, plasmid profile 및 균체단백질 pattern을 비교 분석하였다.

• Journal of Dairy Science and Biotechnology
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• 제19권1호
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• pp.30-38
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• 2001

The most important task in Korean dairy industry is to keep the seasonal and annual balance of raw milk supply and demand. Too much surplus milk supply which causes dumping sale of market milk makes dairy industries get in trouble of management, and eventually affects to farmers and consumers economically. As balancing of supply and demand is so important in the fee economic market system, the adaption of the quota system of milk production and seasonal price differentiation has been recommended very often as a method of controlling the milk supply and demand. However, this recommendation did not go through successfully due to the strong objection of dairy farmers. Recently, the voice of consumer's requirement for safer and more hygienic, and high protein, low fat level dairy product is getting stronger. By knowledge of this kind changes, quality improvement in nutrients and hygiene is the most positive way to expand the volume of milk consumption. To meet the consumer's demand, therefore, it is necessary to revise the level of milk fat content and the hygienic grading system for the payment system of raw milk.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제12권sup1호
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• pp.27-36
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• 2009

Some pediatric patients who can not eat orally depend on enteral tube feedings, and some patients require more nutrients and calories to achieve the catch-up growth. If a patient is counting on the parenteral nutrition, early initiation of enteral feeding, orally or enterally, is a very good for the intestinal mucosal maturity and motility. There are numerous kinds of formulas and supplements for the enteral feeding for neonates, infants, and children. Depending on the intestinal symptoms, allergic symptoms, requirement of special nutrients, we can choose regular infant formula (milk-based, soy-based), protein hydrolysate formula, amino acid hydrolysate formula, elemental formula. Proper use of these formulas would help for the pediatric patients to recover from their diseases, to facilitate the intestinal mucosal maturity and to achieve their goal of growth.

• Asian-Australasian Journal of Animal Sciences
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• 제22권2호
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• pp.296-304
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• 2009

The nutritional significance of essential amino acids, as well as non-essential amino acids, is well documented in poultry production with regards to growth performance and protein accretion. However, the function of amino acids in the stress response is still unclear. L-Pipecolic acid, a L-lysine metabolite in the brain, induced a hypnotic and sedative effect acting via the ${\gamma}$- aminobutyric acid receptors. L-Arginine also induced a sedative effect via its metabolism to L-ornithine. In addition, three-carbon nonessential amino acids like L-alanine, L-serine and L-cysteine also induced sedative effects. These facts suggest that the requirement for amino acids in both essential and non-essential types may require reconsideration to add the concept of stress amelioration in the future.

• 월간한국양록
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• 18호
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• pp.2-10
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• 1993

본 시험은 3마리의 2년생 famale sika deer에게 동일한 에너지 수준하에 단백질 함량($7\%,\;12\%\;17\%$)이 각기 다른 사료를 급여하였을 때, 사료 영양소의 이용성 변화 및 체내 N 대사, 유지를 위한 단백질 요구량, 대사성 분질소 함량 등을 규명하기 위하여 실시하였으며, 결과를 요약하면 다음과 같다. 1. DM, OM, ADF의 소화율을 사료내 단백질 함량에 따른 차이를 보이지 않았으며(P>.1), CP의 소화율은 사료내 단백질 수준이 증가함에 따라 향상되었다(P<.05). 2. 사료내 단백질 함량이 증가함에 따라 분과 뇨로의 N 배출량 모두 증가하였으며(P<.05), 사료내 단백질 수준이 7, 12, $17\%$ 이었을 때 N retention은 각각 26.9, 31, 8, $38.9\%$였다. 3. 혈증 urea-N 함량은 사료내 단백질 함량의 증가에 따라 현저하게 증가하였다.(P<.05) 4. Famale sika deer의 유지수준의 단백질요구량(protein requirement for maintenance)은 $1.81g/kgW^{0.75}/d$다. 5. 대사성 분 질소(metabolic facal N)함량은 $0.32g/kgW^{0.75}/d$였다.

• 약학회지
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• 제47권3호
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• pp.180-183
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• 2003

Crystal structure of TRAF6 in complex with TRAF6-binding sites from CD40 was previously determined. The structure revealed a distinct TRAF6-binding groove of CD40, the key structural determinant of interaction. The structural information leads to a proposed TRAF6-binding motif. This allows the identification of TRAF6-binding sequences in the hIRAK protein, whose functional requirement in IL-1/Toll-like receptor superfamilies-mediated signal transduction is further demonstrated using site-directed mutagenesis. The mutational effects of hIRAK on the down-stream NF-kB signaling shows the importance of the TRAF6 interface for signaling by IL-1/Toll-like receptor superfamilies.

• 약학회지
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• 제51권6호
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• pp.383-388
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• 2007

It has been reported that sulfur-containing intermediates or products in the transsulfuration pathway including S-adenosylmethionine, 5'-methylthioadenosine, glutathione and taurine can prevent liver injury mediated by inflammation response induced by lipopolysaccharide (LPS) treatment. The present study examines the modulation of hepatic metabolism of sulfur amino acid in a model of acute sepsis induced by LPS treatment (5 mg/kg, iv). Serum TNF-alpha and hepatotoxic parameters were significantly increased in rats treated with LPS, indicating that LPS results in sepsis at the doses used in this study. LPS also induced oxidative stress determined by increases in malondialdehyde levels and decreases in total oxy-radical scavenging capacities. Hepatic methionine and glutathione concentrations were decreased, but S-adenosylho-mocysteine, cystathionine, cysteine, hypotaurine and taurine concentrations were increased. Hepatic protein expression of methionine adenosyltransferase, cystathionine beta-synthase and cysteine dioxygenase were induced, but gamma-glutamylcysteine ligase catalytic subunit levels were decreased. The results show that sepsis activates transsulfuration pathway from methionine to cysteine, suggesting an increased requirement for methionine during sepsis.