• Journal of the Korean Society of Clothing and Textiles
• /
• v.17 no.4
• /
• pp.577-586
• /
• 1993

Pesticide protective clothing has not been frequently worn due to its lack of thermal comfort. It is important to develop fabrics which can allow the wearer to work in comfort. One of the possible way to achieve the goal is to produce fabrics with a water- and oil-repellent finish which would resist pesticide penetration but maintain some breathability. The purpose of this study were to evaluate the pesticide barrier properties of untreated and water- and oil-repellent finished nonwoven fabrics. Three types of nonwoven fabrics(Tyvek, Sontara and Kimlon) were used as test specimens. By pad-dry-cure method, each of the specimen was treated with fluorocarbon. The pesticide barrier properties (amount of pesticide penetration and residue) were measured by the gas chromatography. The performance properties of untreated and treated specimens were evaluated with respects to water pepellency(KS K 0590), oil repellency(AATCC 118), water resistance(KS K 0591, AATCC 42), water vapor transmission (KS A 1013) and air permeability(KS K 0570). The results of this study were as follows : 1) The untreated Sontara showed much more amount of pesticide penetration than untreated Tyvek and Kimlon, while the treated Sontara showed little amount of pesticide penetration. 2) After laundering, the amount of pesticide residue in the untreated and treated Sontara was less than that in Tyvek and in Kimlon. 3) Water- and oil-repellent finish improved water repellency, oil repellency, and water resistance of specimens. 4) The untreated Sontara and Kimlon showed higher water vapor transmission and air permeability than untreated Tyvek. Water vapor transmission and air permeability of treated specimen decreased compared to those of untreated.

• Fisheries and Aquatic Sciences
• /
• v.16 no.3
• /
• pp.149-158
• /
• 2013

We demonstrate enhanced growth, innate immunity and protection against hydrogen peroxide ($H_2O_2$)-induced protein oxidation and cellular DNA damage in olive flounder Paralichthys olivaceus fed a chitosan-coated moist pallet (MP) diet. A chitosan-based biopolymer coated MP as the experimental diet and a non-coated MP (control) was fed to olive flounder fish. Growth, including the average weight gain (g/fish), weight gain (%) and feed intake (g) of the fish group fed a chitosan-coated MP diet increased significantly. The survival rate was reported as 100% throughout the experimental period. Immunological parameters indicated higher mucus lysozyme activity and significantly higher fish skin mucus total protein content was observed in fish fed the chitosan-coated MP diet compared to the control. A blood plasma analysis revealed attenuation of cellular DNA and protein oxidative damage caused by $H_2O_2$-induced oxidative stress in the fish fed the chitosan-coated MP diet compared to the control group. Moreover, blood serum biochemical analysis revealed health-promoting effects, including significantly higher hemoglobin and total cholesterol levels in the fish fed the chitosan-coated MP diet compared to the control group. In conclusion, growth, innate immunity and protection against oxidative stresses were improved by feeding of the chitosan-coated MP diet to olive flounder reared in aquaculture.

• Journal of Fisheries and Marine Sciences Education
• /
• v.22 no.4
• /
• pp.529-536
• /
• 2010

This study was conducted to effect of extruded pellets (EPs) and moist pellet (MP) diet on growth and fish health parameters in farm cultured olive flounder Paralichthys olivaceus. Two replicate groups of 2,600 fish per each tank (initial weight of $30.1{\pm}0.2$ g) were fed one of the three EPs (EP1, EP2 and CEP) and one MP for 13 months. In field feeding experiment conducted in commercial flounder farm, survival, growth (30-600 g) and condition factor of fish fed experimental EP1 and EP2 were comparable to those of fish fed MP, but considerably higher feed efficiency and protein efficiency ratio were observed in fish fed experimental EPs. Viable cell counts from diet and water from MP diet were considerably higher than those from EP diet, and lysozyme activity from EP diet was higher than that from MP diet. GOT and GPT of fish fed the EP diet were considerably lower than those from MP group, but total protein and glucose concentration of fish fed the EP groups were not significantly different from that of fish fed the MP. Therefore, these results strongly suggest that EP diets could be developed to replace MP diet without adverse effects on growth performance and to enhance the immunity and protective ability of olive flounder against fish disease such as Vibro, Edwardsiella and Strptococcus.

• Journal of Ginseng Research
• /
• v.28 no.1
• /
• pp.18-26
• /
• 2004

The effect of Panax ginseng administration in muscle inflammatory process induced after eccentric exercise, that causes myofibrillar disruption, was studied. Changes in lipid peroxidation, inflammation, glycogen levels in muscle and release of myocellular proteins to blood were measured. The analyses were performed immediately after eccentric exercise and over week since this period are necessary for the muscle damage-repair cycle. The ginseng extract (100 mg kg$^{-1}$ ) was orally administered to rats for three months, before the eccentric exercise performance. The results showed the protective role of ginseng against skeletal muscle damage. This effect could be associated with their membrane stabilising capacity since creatine kinase (CK) activity was significantly decreased 96 h post-exercise from 523$\pm$70 to 381$\pm$53 and 120 h post-exercise from 443$\pm$85 to 327$\pm$75 in treated animals. $\beta$-glucuronidase activity, as indicator of inflammation, showed a significant reduction of about 15-25% in soleus, vastus and triceps in these post-exercise times. The lipid peroxidation, measured by malondyaldehyde levels, was significantly decreased in the 24 h post-exercise period in soleus and vastus intermedius muscles and on the recovery period. Finally ginseng administration reduced significantly the decrease of the glycogen levels immediately after exercise and when the regenerative process took place (72-168 h post exercise). Collectively, the results have showed that ginseng did not inhibit the vital inflammatory response process associated with the muscle damage-repair cycle but presumably ameliorate the injury.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.19 no.2
• /
• pp.55-62
• /
• 2005

There are many risk factors of electrical shock caused by a minimum of protective devices, loose working environments, deterioration of installations at temporary power installations of construction sites. An insulation cover for instrument transformer(MOF) used in 22.9[kV] class power receiving system hasn't shown good performance in terms of electrical safety because of short clearance between insulation cover and each input and output wire junction part. The insulation cover is easily moved by outside environment as wind or rain because of different size between insulation cover and busing, also can be leaded to breakdown by tracking. Therefore, we have proposed the insulation cover which effectively can prevent from electrical disaster in this paper, and a utility model patent had been registered already. To decrease the electric field concentrated on specific part, we had roundly designed the shape of insulation cover and the clearance between cover and live part was adjusted to be longer than the existing thing. The proposed insulation cover was evaluated by using the electric field solution program.

• Korean Journal of Medicinal Crop Science
• /
• v.24 no.6
• /
• pp.464-470
• /
• 2016

Background: Valeriana fauriei (Valerianaceae) has been used to as a traditional medicine to treat a variety of symptoms, including headache, insomnia, hypertension, and menstrual irregularity. However, the present study investigates the species' antioxidant activity and its inhibition of oxidative DNA damage, which have yet to be studied. Methods and Results: The antioxidant activity was assessed using radical scavenging assays with 1,1-diphenyl-2-picryl hydrazyl (DPPH) and, 2, 2'-azino-bis (3-ethylbenzothiazoline-6 sulfonic acid) diammonium salt (ABTS) and a reducing power assay. The total phenol content was also analyzed, and phenolic compounds were detected using HPLC/UV, whereas the inhibitory effect of Valeriana fauriei on oxidative DNA damage was measured using ${\phi}-174$ RF I plasmid DNA cleavage assay. The DPPH and ABTS radical scavenging activity were $75.17{\pm}3.55%$ and $95.83{\pm}0.63%$, repectively, and the reducing power was $93.14{\pm}1.74$ at $200{\mu}g/m{\ell}$. The total phenol content was $10.24{\pm}0.04mg/g$, whereas chlorogenic acid, catechin, caffeic acid and epicatechin were identified using HPLC/UV, and the ${\phi}-174$ RF I plasmid DNA cleavage assay indicated that V. fauriei provided protection against oxidative damage. Conclusions: The results of the present study suggest that V. fauriei has powerful antioxidant activity that can provide protective effects against the oxidative DNA damage caused by free radicals. The species, therefore, provides a valuable resource for the development of natural pharmaceutical to treat aging, cancer, and degenerative diseases.

• Journal of Ginseng Research
• /
• v.40 no.1
• /
• pp.9-17
• /
• 2016

Background: Alzheimer's disease (AD) is a progressive brain disease, for which there is no effective drug therapy at present. Ginsenoside Rg1 (G-Rg1) and G-Rg2 have been reported to alleviate memory deterioration. However, the mechanism of their anti-AD effect has not yet been clearly elucidated. Methods: Ultra performance liquid chromatography tandem MS (UPLC/MS)-based metabolomics was used to identify metabolites that are differentially expressed in the brains of AD mice with or without ginsenoside treatment. The cognitive function of mice and pathological changes in the brain were also assessed using the Morris water maze (MWM) and immunohistochemistry, respectively. Results: The impaired cognitive function and increased hippocampal $A{\beta}$ deposition in AD mice were ameliorated by G-Rg1 and G-Rg2. In addition, a total of 11 potential biomarkers that are associated with the metabolism of lysophosphatidylcholines (LPCs), hypoxanthine, and sphingolipids were identified in the brains of AD mice and their levels were partly restored after treatment with G-Rg1 and G-Rg2. G-Rg1 and G-Rg2 treatment influenced the levels of hypoxanthine, dihydrosphingosine, hexadecasphinganine, LPC C 16:0, and LPC C 18:0 in AD mice. Additionally, G-Rg1 treatment also influenced the levels of phytosphingosine, LPC C 13:0, LPC C 15:0, LPC C 18:1, and LPC C 18:3 in AD mice. Conclusion: These results indicate that the improvements in cognitive function and morphological changes produced by G-Rg1 and G-Rg2 treatment are caused by regulation of related brain metabolic pathways. This will extend our understanding of the mechanisms involved in the effects of G-Rg1 and G-Rg2 on AD.

• Proceedings of the Korea Concrete Institute Conference
• /
• 2008.04a
• /
• pp.501-504
• /
• 2008

A concrete carbonation model has been constructed that takes account of the diffusion of carbon dioxide through a coating and reaction with calcium hydroxide, and this model has been validated by an accelerated carbonation experiment. (1) By using values for the coatings calculated on the basis of a diffusion.permeation theory as input data for the analysis of diffusion.reaction carbonation in an unsteady state, the effect of the coatings in reducing carbonation can be represented with high accuracy. (2) Through a sensitivity analysis of the diffusion.reaction carbonation model and the experimental results, we found that the diffusion coefficient of calcium hydroxide shows a high interrelationship at 1e-12($m^2/s$). The reaction rate constant for carbonation shows a high interrelationship at 5e-5($m^3/mol/s$).

• Korean Journal of Biological Psychiatry
• /
• v.14 no.2
• /
• pp.106-114
• /
• 2007

Objective : It is suggested that disturbance of dopaminergic system might be related to the possible mechanism of social phobia. The aim of this study was to investigate the possible association of DRD2 TaqI polymorphism and social phobia. Method : Fifty-one patients with social phobia and 200 comparison subjects were tested for DRD2 TaqI A polymorphism. The severity of social phobic symptoms was measured by self-report version of the Liebowitz Social Anxiety Scale(LSAS-SR) and Hamilton anxiety scale(HAM-A). Results : There was no signigicant difference in the genotype, allele frequency, A1 carrier frequency, and heterozygote frequency DRD2 TaqI A polymorphism between the social phobia patients and the control groups. However, we found significant decrease in somatic anxiety of the HAM-A in the patients having A2A2 homozygotes(p=0.014). In addition, patients having A1A2 heterozygotes showed more anxiety in two subscales (p=0.042 in anxiety, p=0.019 in performance) of the LSAS-SR. Conclusion : These results suggest that DRD2 A2 homozygote might have a protective role against somatic anxiety, and molecular heterosis of DRD2 TaqI A polymorphism might be related with more severe anxiety in social phobia.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.19 no.1
• /
• pp.29-36
• /
• 2015

Base isolation is considered as a seismic protective system in the design of next generation Nuclear Power Plants (NPPs). If seismic isolation devices are installed in nuclear power plants then the safety under a seismic load of the power plant may be improved. However, with respect to some equipment, seismic risk may increase because displacement may become greater than before the installation of a seismic isolation device. Therefore, it is estimated to be necessary to select equipment in which the seismic risk increases due to an increase in the displacement by the installation of a seismic isolation device, and to perform research on the seismic performance of each piece of equipment. In this study, modified NRC-BNL benchmark models were used for seismic analysis. The numerical models include representations of isolation devices. In order to validate the numerical piping system model and to define the failure mode, a quasi-static loading test was conducted on the piping components before the analysis procedures. The fragility analysis was performed by using the results of the inelastic seismic response analysis. Inelastic seismic response analysis was carried out by using the shell finite element model of a piping system considering internal pressure. The implicit method was used for the direct integration time history analysis. In addition, the collapse load point was used for the failure mode for the fragility analysis.