• Title/Summary/Keyword: Protection time

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Studies on Development of Escherichia coli Subunit Vaccine against Calf Diarrhea; II. Immunogenicity and Protective Efficacy of Escherichia coli K99 and F41 Pilus Vaccines in Experimental Animals (송아지 대장균(大腸菌) Pilus Vaccine 개발(開發)에 관한 연구(硏究): II. 시험(試驗)백신의 면역원성(免疫原性) 및 방어효과(防禦效果))

  • Kim, Jong-man;Yoon, Young-dhuk;Park, Jeung-moon;Kim, Bong-hwan
    • Korean Journal of Veterinary Research
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    • v.26 no.1
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    • pp.103-108
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    • 1986
  • The oil emulsion and alhydrogel pilli vaccines were prepared from a strain(O9: K35, K99, F41) of enterotoxigenic Escherichia coli isolated from calves with diarrhea and their immunogenicity was tested in guinea-pigs, pregnant goats and cows. Serum antibody responses to K99 and F41 antigens in guinea-pigs given experimental oil and gel vaccines peaked at 4 and 6 weeks after vaccinations. At that time, the mean hemagglutination inhibition titers to K99 and F41 antigens in guinea-pigs given oil vaccine were 1:25 and 1:1, 218 and those given gel vaccine were 1:54 and 1:724 respectively. Agglutinin titers in pregnant goats given the oil vaccine were significantly higher(mean 1:2,347) compared to those of control group(mean 1:160). Less than 12.5% of goatlings from vaccinated goats developed scours compared to nearly 100% in control group after oral challenge with enterotoxigenic Escherichia coil within 24 hours after birth. The highest agglutinin titers of cow serum and colostrum and of the serum of calves 48 hours after birth from cows given oil vaccine were 1:256, 1:512 and 1:64 respectively. On the other hand, those titers of serum and colostrum and of the serum of nursing calves from nonvaccinated cows were 1:8, 1:16 and 1:20 respectively. The protective efficacy of the oil emulsion vaccine was 72.1% under field conditions. These results strongly indicated that the vaccine could be applied for protection of diarrhea caused by enterotoxigenic Escherichia coli in calves.

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A Simulation of the Runoff and the NPS Pollutants Discharge using SWMM Model (SWMM 모형을 이용한 도시 유역의 유출 및 NPS 오염물 배출 모의)

  • 신현석;윤용남
    • Water for future
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    • v.26 no.3
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    • pp.125-135
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    • 1993
  • This study was conducted for two purposes. The first was the selection of the proper model for the urban runoff, and NPS(non-point source) loads and the second was the adjustment of the selected model through the calibration and the verification of the observed data on an urban drainage basin. The selected model for this study was the Storm Water Management Model(SWMM) developed and maintained by the US Environmental Protection Agency(EPA). In particular, the Runoff Block for the surface discharge and the Transport Block for the flow routing was used. The study basin is Youngdu basin, which is a typical developed urban drainage basin. The four rainfall events for the runoff and the two for the four NPS pollutants(SS, BOD, COD and TN) were used for the calibration and the estimation of the model parameters. This study performed the calibration with regard to the peak discharge, the time to peak discharge, the volume and the relative error for three items. It was shown that SWMM can successfully be used for the prediction of the runoff and the NPS pollutants discharge. The result of this study can be used as the basis for the analysis of the correlation between the runoff and the NPS pollutants discharges, and the analysis of the mass balance with the monthly and annual NPS loads in an urban drainage basin.

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Flight Control of Tilt-Rotor Airplane In Rotary-Wing Mode Using Adaptive Control Based on Output-Feedback (출력기반 적응제어기법을 이용한 틸트로터 항공기의 회전익 모드 설계연구)

  • Ha, Cheol-Keun;Im, Jae-Hyoung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.38 no.3
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    • pp.228-235
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    • 2010
  • This paper deals with an autonomous flight controller design problem for a tilt-rotor aircraft in rotary-wing mode. The inner-loop algorithm is designed using the output-based approximate feedback linearization. The model error originated from the feedback linearization is cancelled within allowable tolerance by using single-hidden-layer neural network. According to Lyapunov direct stability theory, the adaptive update law is derived to run the neural network on-line, which is based on the linear observer dynamics. Moreover, the outer-loop algorithm is designed to track the trajectory generated from way-point guidance. Especially, heading and flight-path angle line-of-sight guidance are applied to the outer-loop to improve accuracy of the landing tracking performance. The 6-DOF nonlinear simulation shows that the overall performance of the flight control algorithm is satisfactory even though the collective input response shows instantaneous actuator saturation for a short time due to the lack of the neural network and the saturation protection logic in that loop.

Development of Surface Survey System for Archaeological Site using Mobile GPS and GIS Technique (모바일 GPS/GIS기술을 이용한 유적 지표조사 시스템 구현)

  • Jang, Yong-Gu
    • Journal of the Korean Association of Geographic Information Studies
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    • v.9 no.2
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    • pp.91-101
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    • 2006
  • Recently, as a part of NGIS project, cultural-assets digital map is produced by cultural properties administration and local autonomous entities. Cultural-assets unified GIS(Geographic Information System) is essential to cultural properties managers and other organizations which are executing land related business for appling it at planning stage. With explosive national land developments, it has been obligated to implement surface survey by the cultural properties protection Art. In this paper, we develope a MSSS(Mobile Surface Survey System) and central GIS management system using CDMA wireless network, real time DGPS and C/S GIS technologies. And we suggest a construction-plan of cultural-assets digital map drawing and managing system by Archaeologist using developed system by this study.

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Case analysis of trade dispute between Korea and India (한.인도간의 통상분쟁 현황과 사례 분석 -인도의 반덤핑 관세정책을 중심으로-)

  • Lee, Jong-Won
    • International Commerce and Information Review
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    • v.12 no.3
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    • pp.391-412
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    • 2010
  • As traditional import regulations have decreased all over the world in recent decades, the usage of "unconventional" trade protection measures has grown in the developing countries. In particular, antidumping investigations have risen rapidly and have growing in India and China. Therefore, this thesis aims to provide countermeasures to our government and Korean exporting companies by studying characteristics of antidumping. India is one of the most frequent initiators of antidumping cases by protecting their industries and impeding imports from FTA. This year, economic exchanges of Korea and India will be increasing by the conclusion of CEPA. This will lead to the increase of dispute by import regulations. Under such circumstances, to decrease Indian antidumping cases Korea will respond as follows. i)If antidumping laws, system and practice of India have injustice or are different from WTO rules, our government will have to indicate injustice and actively urge Indian government to make corrections. For example, they are continuous bilateral contact about the problems, fallacy of calculation of dumping margin, and intense investigations into cause and effect relationship and losses in dumping market, ect. ii)Our government should give more support to the small and medium exporting company which have difficulties in dealing with trade conflicts, counseling, arbitrating a lawyer. iii)Our government which is in control of domestic trade relief system should strengthen its investigation ability about new regulations and moniter import regulations of India. Over the long time, Korean companies need to export competitive advantage items of a higher value-added business and build solidarity by technology transfer. Accordingly, that will result in the decrease of trade dispute in India.

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Control of Smart Base-isolated Benchmark Building using Fuzzy Supervisory Control (퍼지관리제어기법을 이용한 스마트 면진 벤치마크 건물의 제어)

  • Kim, Hyun-Su;Roschke P. N.
    • Journal of the Earthquake Engineering Society of Korea
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    • v.9 no.4 s.44
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    • pp.55-66
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    • 2005
  • The effectiveness of fuzzy supervisory control technique for the control of seismic responses of smart base isolation system is investigated in this study. To this end, first generation base isolated building benchmark problem is employed for the numerical simulation. The benchmark structure under consideration is an eight-story base isolated building having irregular plan and is equipped with low-damping elastometric bearings and magnetorheological (MR) dampers for seismic protection. Lower level fuzzy logic controllers (FLC) for far-fault or near-fault earthquakes are developed in order to effectively control base isolated building using multi-objective genetic algorithm. Four objectives, i.e. reduction of peak structural acceleration, peak base drift, RMS structural acceleration and RMS base drift, are used in multi-objective optimization process. When earthquakes are applied to benchmark building, each of low level FLCs provides different command voltage and supervisory fuzzy controller combines two command voltages io one based on fuzzy inference system in real time. Results from the numerical simulations demonstrate that base drift as well as superstructure responses can be effectively reduced using the proposed supervisory fuzzy control technique.

The clinical Rxperiences and Long Term Results with 369 cases of Coronary Artery Bypass Graft Surgery (관상동맥 우회로 조성수술 369례의 임상성적 및 장기결과)

  • 유경종
    • Journal of Chest Surgery
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    • v.28 no.6
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    • pp.583-590
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    • 1995
  • The three hundred and sixty nine patients who underwent either isolated or concomitant coronary artery bypass graft surgery since May, 1977 till December, 1993 at the Yonsei University Cardiovascular center were studied with respects to the incidence of operative risk factors, surgical methodology and consequent results. The patients were classified into two periods, according to the time of the surgery in relation to the date of the opening of the Yonsei cardiovascular center. Period I[1977 to 1990 , consisting of the patients who underwent surgery prior to the opening date, harboured a total of 189 patients with the mean age of 55 years, and the second, Period II[1991 to 1993 , those who underwent after the opening, of 180 patients with the mean age of 60 years. The Period II patients were involved in more operative risk factors, compared to the ones in Period I. The anatomy of the coronary arteries of the patients of Period II were more likely to have multilesional and left main disease. The patients in Period I were older, had more prominent left ventricular dysfunction and were more likely to be exposed to the risk factors. The number of implanted grafts were greater period II[average of 2.5 grafts per patient in Period I VS 3.2 in Period II and the frequency which the used left internal mammary artery was also significantly higher in Period II[49 and 104 cases in Period I and Period II . The incidence of perioperative myocardial infarction was 20 patients[10.6% in Period I, 14 patients[7.8% in period II. And the operative mortality was 20 patients[10.6% in period I, 8 patients[4.4% in period II. In conclusion we think that the operative results have improved in Period II, compared to that of Period I, in spite of the higher risks, due to accumulation of surgical experiences, improved surgical techniques and myocardial protection, specialized teamwork, application of the intraoperative TEE and appropriate pharmacological interventions by anesthesiologist.

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A Study on the Economic Structure of Mexican Northern Borderlands in Relation to the North American Free Trade Agreement (멕시코 북부 국경지대의 경제구조 변화에 관한 고찰)

  • Lee, Jeon;Back, Jong-Gook
    • Journal of the Korean Geographical Society
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    • v.32 no.2
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    • pp.155-174
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    • 1997
  • This paper's main objective is to present an assessment of the impact of NAFTA on the economic structure of the Mexican northem borderlands. The NAFTA is the strategy of a free trade agreement with the United States and Canada, first mentioned by Salinas in June 1990 and established since January 1994. Mexican govemment permitted factories called maquiladoras at the northem borderlands for the first time in 1965. in the early 1980s Mexico was in a deep economic crisis and the international environment was adverse to Mexico. Mexico began to move toward an open economy and abandoned the import-substitution industrialization model that characterized Mexico since the 1930s. Through the new economic reform, the market system was preferred to the regulation; the private ownership, to the public ownership; and the competition, to the protection. The most phenomenal urbanization in northem Mexico has occurred around the major crossing points along the Mexico-U.S. border. The rapid urbanization in northern Mexico has been much due to the industrialization, brought about bv the maquiladora programs and, recently, by the NAFTA.

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Legal Approach to the Concept of 'Sustainability' in Sustainable Development (지속적 개발의 '지속성' 개념에 관한 법학적 접근)

  • Seo, Won-Sang
    • Journal of Environmental Policy
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    • v.3 no.2
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    • pp.59-87
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    • 2004
  • In its Declaration of Principles, the United Nations Conference on Environment and Development recommends that, "to achieve sustainable development and a higher quality of life for all people, states should reduce and eliminate unsustainable patterns of production and consumption...." This notion of sustainability lies at the core of many "commons" problems, where the central issue is to enable "individuals to sustain long-term, productive use of natural resource systems". In other worlds, a common definition of "sustainability" captures the idea of aligning human consumption with the capacity of ecological systems to supply, over a long period of time, such natural resources as air, soil, or water on which production depends. The concept of sustainability raises all sorts of political, social, and economic questions about the distribution of environmental protection. For sustainable community development to be addressed, these questions must be raised. In order to convince different citizenry of the necessity of sustainability, these questions must also be answered. This is where questions of equity, justice, and fairness arise. Sustainability and equity require that we deal with nature as an undivided whole, with no part being unsustainable. Sustainability and social policy also requires that we deal with the human population as an undivided whole. We simply cannot move people around the planet to either perpetuate past practices of earth exploitation or to implement sustainable planning. Everyone must work with the people inhabiting sensitive ecological areas, especially areas of regeneration. In the sustainable global community, we are as strong as our weakest link, or our most toxic community. This is the undeniable driving force for the infusion of equity into the sustainable development debate.

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Effects of Salicylic Acid on Oxidative Stress and UV-B Tolerance in Cucumber Leaves (살리실산이 오이 잎의 산화적 스트레스와 UV-B 내성에 미치는 영향)

  • Hong, Jung-Hee;Kim, Tae-Yun
    • Journal of Environmental Science International
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    • v.16 no.12
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    • pp.1345-1353
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    • 2007
  • The effect of salicylic acid(SA) on antioxidant system and protective mechanisms against UV-B induced oxidative stress was investigated in cucumber(Cucumis sativus L.) leaves. UV-B radiation and SA were applied separately or in combination to first leaves of cucumber seedlings, and dry matter accumulation, lipid peroxidation and activities of antioxidant enzymes were measured in both dose and time-dependant manner. UV-B exposure showed reduced levels of fresh weight and dry matter production, whereas SA treatment significantly increased them. SA noticeably recovered the UV-B induced inhibition of biomass production. UV-B stress also affected lipid peroxidation and antioxidant enzyme defense system. Malondialdehyde(MDA), a product of lipid peroxidation, was greatly increased under UV-B stress, showing a significant enhancement of a secondary metabolites, which may have antioxidative properties in cucumber leaves exposed to UV-B radiation. Combined application of UV-B and SA caused a moderate increase in lipid peroxidation. These results suggest that SA may mediate protection against oxidative stress. UV-B exposure significantly increased SOD, APX, and GR activity compared with untreated control plants. Those plants treated with 1.0 mM SA showed a similar pattern of changes in activities of antioxidant enzymes. SA-mediated induction of antioxidant enzyme activity may involve a protective accumulation of $H_2O_2$ against UV-B stress. Moreover, their activities were stimulated with a greater increase by UV-B+SA treatment. The UV-B+SA plants always presented higher values than UV-B and SA plants, considering the adverse effects of UV-B on the antioxidant cell system. ABA and JA, second messengers in signaling in response to stresses, showed similar mode of action in UV-B stress, supporting that they may be important in acquired stress tolerance. Based on these results, it can be suggested that SA may participates in the induction of protective mechanisms involved in tolerance to UV-B induced oxidative stress.