• Smart Structures and Systems
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• v.30 no.6
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• pp.687-701
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• 2022

Inevitable response loss under complex operational conditions significantly affects the integrity and quality of measured data, leading the structural health monitoring (SHM) ineffective. To remedy the impact of data loss, a common way is to transfer the recorded response of available measure point to where the data loss occurred by establishing the response mapping from measured data. However, the current research has yet addressed the structural condition changes afterward and response mapping learning from a small sample. So, this paper proposes a novel data driven structural response reconstruction method based on a sophisticated designed generating adversarial network (UAGAN). Advanced deep learning techniques including U-shaped dense blocks, self-attention and a customized loss function are specialized and embedded in UAGAN to improve the universal and representative features extraction and generalized responses mapping establishment. In numerical validation, UAGAN efficiently and accurately captures the distinguished features of structural response from only 40 training samples of the intact structure. Besides, the established response mapping is universal, which effectively reconstructs responses of the structure suffered up to 10% random stiffness reduction or structural damage. In the experimental validation, UAGAN is trained with ambient response and applied to reconstruct response measured under earthquake. The reconstruction losses of response in the time and frequency domains reached 16% and 17%, that is better than the previous research, demonstrating the leading performance of the sophisticated designed network. In addition, the identified modal parameters from reconstructed and the corresponding true responses are highly consistent indicates that the proposed UAGAN is very potential to be applied to practical civil engineering.

• The Korea Journal of Herbology
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• v.32 no.3
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• pp.37-44
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• 2017

Objectives : The application of DNCB (1-chloro-2,4-dinitrochlorobenzene) can cause cellular immunity allergic reaction such as erythema or edema on NC/Nga mice and combinational function of cells participating in immunity increase inflammatory mediator. In this study, the effects of cypress essential oil on NC/Nga mice have been assessed. Methods : Male SPF NC/Nga mice aged 8 weeks have been used for atopic dermatitis induction skin. 1% DNCB was applied on ears and backs of which hair was removed using clipper on $1^{st}$ day and 0.4% DNCB was applied three times a week for 3 weeks. In this study, cypress essential oil has been treated 1 time a day for 3 weeks after application of DNCB to induce atopic dermatitis on skin for further experiments. Results : This study shows that inhalation or application of cypress essential oil reduced edema in ears and the thickness of epidermis induced by DNCB treatment. And it can be known that treatment of cypress essential oil inhibited mast cell proliferation and reduced IgE level similar to that of the negative control especially when cypress essential oil was inhaled by the mice. Synthetic oil showed the effects lower than those of cypress essential oil. Conclusions : Inhalation or direct application of cypress essential oil on skin reduced IgE level in blood and prohibits the proliferation of mast cell, from which it can be known that cypress essential oil can be effectively used to reduce the symptoms of atopic dermatitis.

• Journal of Ginseng Research
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• v.46 no.1
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• pp.79-90
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• 2022

Background: Herbal medicines are popular approaches to capably prevent and treat obesity and its related diseases. Excessive exposure to dietary lipids causes oxidative stress and inflammation, which possibly induces cellular senescence and contribute the damaging effects in brain. The potential roles of selective enhanced ginsenoside in regulating high fat diet (HFD)-induced brain damage remain unknown. Methods: The protection function of Ginsenoside F1-enhanced mixture (SGB121) was evaluated by in vivo and in vitro experiments. Human primary astrocytes and SH-SY5Y cells were treated with palmitic acid conjugated Bovine Serum Albumin, and the effects of SGB121 were determined by MTT and lipid uptake assays. For in vivo tests, C57BL/6J mice were fed with high fat diet for 3 months with or without SGB121 administration. Thereafter, immunohistochemistry, western blot, PCR and ELISA assays were conducted with brain tissues. Results and conclusion: SGB121 selectively suppressed HFD-induced oxidative stress and cellular senescence in brain, and reduced subsequent inflammation responses manifested by abrogated secretion of IL-6, IL-1β and TNFα via NF-κB signaling pathway. Interestingly, SGB121 protects against HFD-induced damage by improving mitophagy and endoplasmic reticulum-stress associated autophagy flux and inhibiting apoptosis. In addition, SGB121 regulates lipid uptake and accumulation by FATP4 and PPARα. SGB121 significantly abates excessively phosphorylated tau protein in the cortex and GFAP activation in corpus callosum. Together, our results suggest that SGB121 is able to favor the resistance of brain to HFD-induced damage, therefore provide explicit evidence of the potential to be a functional food.

• Journal of Ginseng Research
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• v.46 no.1
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• pp.104-114
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• 2022

Background: Abnormalities of myelin, which increases the efficiency of action potential conduction, are found in neurological disorders. Korean Red Ginseng (KRG) demonstrates therapeutic efficacy against some of these conditions, however effects on oligodendrocyte (OL)s are not well known. Here, we examined the effects of KRG-derived components on development and protection of OL-lineage cells. Methods: Primary OL precursor cell (OPC) cultures were prepared from neonatal mouse cortex. The protective efficacies of the KRG components were examined against inhibitors of mitochondrial respiratory chain activity. For in vivo function of Rb1 on myelination, after 10 days of oral gavage into adult male mice, forebrains were collected. OPC proliferation were assessed by BrdU incorporation, and differentiation and myelination were examined by qPCR, western blot and immunocytochemistry. Results: The non-saponin promoted OPC proliferation, while the saponin promoted differentiation. Both processes were mediated by AKT and extracellular regulated kinase (ERK) signaling. KRG extract, the saponin and non-saponin protected OPCs against oxidative stress, and both KRG extract and the saponin significantly increased the expression of the antioxidant enzyme. Among 11 major ginsenosides tested, Rb1 significantly increased OL membrane size in vitro. Moreover, Rb1 significantly increased myelin formation in adult mouse brain. Conclusion: All KRG components prevented OPC deaths under oxidative stress. While non-saponin promoted proliferation, saponin fraction increased differentiation and OL membrane size. Furthermore, among all the tested ginsenosides, Rb1 showed the biggest increase in the membrane size and significantly enhanced myelination in vivo. These results imply therapeutic potentials of KRG and Rb1 for myelin-related disorders.

• Fashion & Textile Research Journal
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• v.24 no.4
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• pp.471-478
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• 2022

In roadside workplaces, more attention should be paid to the safety of workers. The roadside workers underestimate the effect of the brightness of their clothes and judge that drivers will recognize them easily, and the drivers misjudge that the roadside workers are far away and that the vehicle can be stopped in sufficient time. Therefore, customized safety education reflecting this and wearing work clothes with certified visibility functions are required. In Korea, it is not compulsory for roadside workers and vehicle guide attendants to wear work clothes with a visibility function. In this study, the distance ahead perceived by drivers was measured using manikins wearing certified and non-certified reflective safety vests. The perception distance of the non-certified reflective safety vest was 1.4 times longer than that of the certified reflective safety vest, thus confirming the importance of wearing a certified reflective safety vest. To prevent roadside workers from suffering traffic accidents, we propose the enactment of a law that makes it mandatory for them to wear high-visibility safety clothing. Specifically, Article 32 of the Enforcement Regulation of the Road Traffic Act should include high-visibility safety clothing in life protection equipment, and additionally, to prevent secondary accidents, we propose the enactment of a law requiring the installation and wearing of certified reflective safety vests in vehicles.

• Journal of the Society of Disaster Information
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• v.19 no.3
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• pp.582-596
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• 2023

Purpose: This study aims to explore the ways to improve the security of temporary shelters in case of nuclear power plant accidents. Method: In this study, we mainly rely on the case studies on previous nuclear power plant accidents-Chernobyl, Fukushima, and Three Mile Island (TMI) cases. Result: The current radiation emergency response plans for nuclear power plant accidents center around the evacuation procedure. As a result, the concept of "shelter in place" has been understood as a means of assisting resident evacuation. However, based on the case studies, we find that encouraging shelter in place, rather than simply emphasizing evacuation, would help minimize unnecessary casualties, especially in case of the accidents rated greater than or equal to INES 5. To facilitate better shelter in place, we recommend utilize apartments as temporary shelters and suggest some possible improvements to ensure those apartments could be equipped with technologies for high radiation protection. Conclusion: To ensure better shelter in place, we recommend using apartments as temporary shelters, and we seek to supplement the function of apartments by using shielding, positive pressure, and sealing technologies.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.04a
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• pp.871-874
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• 2011

The fast emerging of network technology and the high demand of computing resources have prompted many organizations to outsource their storage and computing needs. Cloud based storage services such as Microsoft's Azure and Amazon's S3 allow customers to store and retrieve any amount of data, at anytime from anywhere via internet. The scalable and dynamic of the cloud storage services help their customer to reduce IT administration and maintenance costs. No doubt, cloud based storage services brought a lot of benefits to its customer by significantly reducing cost through optimization increased operating and economic efficiencies. However without appropriate security and privacy solution in place, it could become major issues to the organization. As data get produced, transferred and stored at off premise and multi tenant cloud based storage, it becomes vulnerable to unauthorized disclosure and unauthorized modification. An attacker able to change or modify data while data inflight or when data is stored on disk, so it is very important to secure data during its entire life-cycle. The traditional cryptography primitives for the purpose of data security protection cannot be directly adopted due to user's lose control of data under off premises cloud server. Secondly cloud based storage is not just a third party data warehouse, the data stored in cloud are frequently update by the users and lastly cloud computing is running in a simultaneous, cooperated and distributed manner. In our proposed mechanism we protect the integrity, authentication and confidentiality of cloud based data with the encrypt- then-upload concept. We modified and applied proxy re-encryption protocol in our proposed scheme. The whole process does not reveal the clear data to any third party including the cloud provider at any stage, this helps to make sure only the authorized user who own corresponding token able to access the data as well as preventing data from being shared without any permission from data owner. Besides, preventing the cloud storage providers from unauthorized access and making illegal authorization to access the data, our scheme also protect the data integrity by using hash function.

• Animal Bioscience
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• v.36 no.7
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• pp.1034-1043
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• 2023

Objective: Two serine protease inhibitors, peptidase inhibitor 3 (PI3) and secretory leukocyte protease inhibitor (SLPI), play important roles in protease inhibition and antimicrobial activity, but their expression, regulation, and function at the maternal-fetal interface in pigs are not fully understood. Therefore, we determined the expression and regulation of PI3 and SLPI in the endometrium throughout the estrous cycle and at the maternal-fetal interface in pigs. Methods: Endometrial tissues during the estrous cycle and pregnancy, conceptus tissues during early pregnancy, and chorioallantoic tissues during mid to late pregnancy were obtained, and the expression of PI3 and SLPI was analyzed. The effects of the steroid hormones estradiol-17β (E2) and progesterone (P4) on the expression of PI3 and SLPI were determined in endometrial explant cultures. Results: PI3 and SLPI were expressed in the endometrium during the estrous cycle and pregnancy, with higher levels during mid to late pregnancy than during the estrous cycle and early pregnancy. Early-stage conceptuses and chorioallantoic tissues during mid to late pregnancy also expressed PI3 and SLPI. PI3 protein and SLPI mRNA were primarily localized to endometrial epithelia. In endometrial explant cultures, the expression of PI3 was induced by increasing doses of P4, and the expression of SLPI was induced by increasing doses of E2 and P4. Conclusion: These results suggest that the PI3 and SLPI expressed in the endometrium and conceptus tissues play an important role in antimicrobial activity for fetal protection against potential pathogens and in blocking protease actions to allow epitheliochorial placenta formation.

• Current Optics and Photonics
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• v.7 no.1
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• pp.38-46
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• 2023

Optical Fourier-domain reflectometry (OFDR) sensors have been widely used to measure distances with high resolution and speed in a noncontact state. In the electroplating process of a printed circuit board, it is critically important to monitor the copper-plating thickness, as small deviations can lead to defects, such as an open or short circuit. In this paper we employ a phase-based OFDR sensor for in situ relative distance sensing of a sample with nanometer-scale resolution, during electroplating. We also develop an optical-path difference (OPD)-regulated sensing probe that can maintain a preset distance from the sample. This function can markedly facilitate practical measurements in two aspects: Optimal distance setting for high signal-to-noise ratio OFDR sensing, and protection of a fragile probe tip via vertical evasion movement. In a sample with a centimeter-scale structure, a conventional OFDR sensor will probably either bump into the sample or practically out of the detection range of the sensing probe. To address this limitation, a novel OPD-regulated OFDR system is designed by combining the OFDR sensing probe and linear piezo motors with feedback-loop control. By using multiple OFDR sensors, it is possible to effectively monitor copper-plating thickness in situ and uniformize it at various positions.

• Korean Journal of Social Welfare
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• v.69 no.4
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• pp.75-97
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• 2017

This study examined the effect of female adolescent's the victimization experience of sexual assault to suicidal ideation. Futhermore, defined the moderation effects of parent-adolescent TSL communication in associations between the victimization experience of sexual assault and suicidal ideation. Participants were 1,032, South Korea middle and high school Female students in a national community sample. Data was analyzed by multiple-regression analysis with SPSS 18.0. The results indicates that the victimization experience of sexual assault was 16.2%. There is a positive relationship between victimization experience of sexual assault and suicidal ideation. Also, parent-adolescent TSL communication had a moderating effect of protection factor between sexual assault and suicidal ideation. Result show, the solution for prevention on sexual assault of adolescent is to open the discussion regarding the solution and improvement of family function in order to reduce the frequency of suicidal ideation.