• Title/Summary/Keyword: Protection function

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Effects of Vitamins C and E on Hepatic Drug Metabolizing Function in Nypoxia/Reoxygenation (저산소 및 산소재도입시 vitamin C와 E가 간장 약물대사 기능에 미치는 영향)

  • 윤기욱;이상호;이선미
    • YAKHAK HOEJI
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    • v.44 no.3
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    • pp.237-244
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    • 2000
  • Liver isolated from 18 hours fasted rats was subjected to $N_2$hypoxia (for 45 min) followed by reoxygenation (for 30 min). The perfusion medium used was Krebs-Henseleit bicarbonate buffer (pH 7.4, $37^{\circ}C$). Vitamin C (0.5 mM) and trolox C (0.5 mM), soluble vitamin E analog, were added to perfusate. Lactate dehydrogenase (LDH), total glutathione, oxidized glutathione, lipid peroxide and drug-metabolizing enzymes were measured. After hypoxia LDH significantly increased but this increase was attenuated by vitamin C and combination of vitamin C and E. Total glutathione and oxidized glutathione in perfusate markedly increased during hypoxia and this increase was inhibited by vitamins C, E and its combination. Similarly; oxidized glutathione and lipid peroxide in liver tissue increased after hypoxia and reoxygenation and this increase was inhibited by vitamin I and combination of vitamin C and E. Hepatic drug metabolizing function (phase I, II) were suppressed during hypoxia but improved during reoxygenation. While vitamins C and E only increased glucuronidation, the combination of vitamin C and E increased the oxidation, glucuronidation and sulfation. Our findings suggest that vitamins C and E synergistically ameliorates hepatocellular damage as indicated by abnormalities in drug metabolizing function during hypoxia/reoxygenation and that this protection is in major part, caused by decreased oxidative stress.

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Design of Intelligent Servocontroller for Proportional Flow Control Solenoid Valve with Large Capacity (지능형 대용량 비례유량제어밸브 서보컨트롤러 설계)

  • Jung, G.H.
    • Transactions of The Korea Fluid Power Systems Society
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    • v.8 no.3
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    • pp.1-7
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    • 2011
  • As the technologies of electronic device have advanced these days, most of mechanical systems are designed with electronic control unit to take advantage of control parameter adaption to operating conditions and firmware flexibilities as well. On-board diagnosis, which detects the system malfunction and identifies potential source of error with its own diagnostic criteria, and fail-safe that can switch the mode of operation in view of recognized error characteristics enables easy maintenance and troubleshooting as well as system protection. This paper dealt with the development of diagnosis and fail-safe function for proportional flow control valve. All type of errors related to valve control system components are investigated and assigned to a specific hexadecimal codes. Cumulative error detection algorithm is applied in order for the sensitivity and reliability to be appropriate. Embedded simulator which runs simultaneously with system program provides the virtual error simulation environment for expeditious development of error detection algorithm. The diagnosis function was verified both with solenoid valve and embedded simulator test and it will enhance the valve control system monitoring function.

A study on development of CATIA V5 file security system using CAA (CAA를 이용한 CATIA V5 파일보안시스템 개발에 관한 연구)

  • Chae H.C.;Park D.S.;Byun J.H.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.417-418
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    • 2006
  • CATIA V5 is one of the most preferred softwares in product design for domestic and industrial use. But with the development of the IT industry, design data by CATIA V5 can easily be hacked and stolen especially via the internet and through assistance storage medium. The design data could be protected through executive, physical and technical security system. The best way to maintain confidentiality of data from unauthorized access is to have a cryptosystem of the technical security. In this paper, a cryptosystem for the protection of design data was being proposed. The memory contains the file information made by the New and Open function of CATIA V5. No error can be expected even if the file changed before of after the application of Save and Open function, A cryptosystem was constructed in CATIA V5 by inserting crypto algorithm before and after the I/O process. The encryption/decryption algorithm of each function was based on the complex cipher, which applied permutation cipher and transpose cipher. The file security system was programmed in CAA V5 and Visual C++.

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A Study on Development of CATIA V5 File Security System Using CAA (CAA를 이용한 CATIA V5 파일보안시스템 개발에 관한 연구)

  • Chae, Hee-Chang;Park, Doo-Seob;Byun, Jae-Hong
    • Journal of the Korean Society for Precision Engineering
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    • v.24 no.5
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    • pp.77-81
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    • 2007
  • CATIA V5 is one of the most preferred softwares in product design for domestic and industrial use. But with the development of the IT industry, design data by CATIA V5 can easily be hacked and stolen especially via the internet and through assistance storage medium. The design data could be protected through executive, physical and technical security system. the best way to maintain confidentiality of data from unauthorized access is to have a cryptosystem of the technical security. In this paper, a cryptosystem for the protection of design data was being proposed. The memory contains the file information made by the New and Open function of CATIA V5. No error can be expected even if the file changed before of after the application of Save and Open function. A cryptosystem was constructed in CATIA V5 by inserting crypto algorithm before and after the I/O process. The encryption/decryption algorithm of each function was based on the complex cipher, which applied permutation cipher and transpose cipher. The file security system was programmed in CAA V5 and Visual C++.

A Study for the Calculation of Instream Flow in the Rehabilitation of Urban stream (도심하천 복원에 따른 하천유지유량 산정 연구)

  • Choi, Gye Woon;Chang, Yun Gyu;Han, Man Sin
    • Proceedings of the Korea Water Resources Association Conference
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    • 2004.05b
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    • pp.448-452
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    • 2004
  • Instream flow is necessary to manage the basic function of the rivers. The evaluation method of instream flow in a big river has been studied widely. However, the study in a urban hasn't researched. In theses days the environmental function of a river becomes very important. The evaluation method and secure of instream flow are basic conditions to perform it. Especially view of stream, recreation, protection of ecology are highly demanded In a urban according to the multipurpose of river spaces. In this paper the evaluation methods of instream flow were compared and investigated with many papers. This paper presents a proper evaluation procedure of instream flow in a urban stream through comparison and examination. According to the demanded hydraulic conditions the method can be considered the environmental function depend on the purpose of river restoration. The relationship of the coefficient of roughness and the slope of the river bed were examinated in order to estimate the minimum instream flow corresponding to proper Hydraulic conditions. Also calculate the instream flow of Sueng-gi stream in In-cheon.

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Development of the Power System Fault Diagnostic Algorithm for the Proton Accelerator Research Center of PEFP (양성자가속기 연구센터 전력계통 고장진단 알고리즘 개발)

  • Mun, Kyeong-Jun;Jeon, Gye-Po;Lee, Seok-Ki;Kim, Jun-Yeon;Jung, W.;Yoo, Suk-Tae
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.685-686
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    • 2007
  • This paper presents an application of power system fault diagnostic algorithm for the PEFP Proton Accelerator Research Center using neural network. Proposed fault diagnostic system is constructed by the radial basis function (RBF) neural network because it has the capabilities of the pattern classification and function approximation of any nonlinear function. Proposed system identifies faulted section in the power system based on information about the operation of protection devices such as relays and circuit breakers. In this paper, parameters of the RBF neural networks are tuned by the GA-TS algorithm, which has the global optimal solution searching capabilities. To show the validity of the proposed method, proposed algorithm has been tested with a practical power system in Proton Accelerator Research Center of PEFP.

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Electric Properties of the Laminate Type PTC(Positive Temperature Coefficient of Resistance) Thermistor According to Polymer Blowing Agent (유기발포제에 따른 적층형 PTC(Positive Temperature Coefficient of Resistance) 써미스터의 전기적 특성)

  • Lee, Mi-Jai;Hwang, Jong-Hee;Kim, Jin-Ho;Lim, Tae-Young
    • Korean Journal of Materials Research
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    • v.22 no.12
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    • pp.658-663
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    • 2012
  • The electrical properties of a laminated SMD type PTC thermistor for microcircuit protection were investigated as a function of polymer blowing agent addition. Green ceramics for multilayered $BaTiO_3$-based PTCRs were formed by doctor blade method of barium titanate powders; we successfully laminated the sintered ceramic chips to obtain 10 layer chip PTCRs with PTC effect. The sintered density increases with increasing sintering temperature. The electrical properties of the sintered samples were strongly dependent on the calcination and addition of a polymer blowing agent. When $BaTiO_3$ powders containing 0.2 mol% of $Y_2O_3$ were calcined at $1000^{\circ}C$ for 2 hrs, the resistivity jump was of 1-2 orders of magnitude. The resistivity at room temperature increases according to the polymer blowing agent addition. Also, the sample using the calcined powder showed a lower resistivity than that of the sample prepared using powders without calcinations. With an increase in the OBSH, the magnitude of the resistivity jumped as a function of the temperature increase. The resistivity of the sintered bodies after the addition of 0.5 wt% polymer blowing agent at $1290^{\circ}C$ for 2 h was shown to be about $8.5{\Omega}{\cdot}cm$; the jump order of the sintered bodies was shown to be on the order of $10^2$.

The PTCR Characteristics of the Laminated SMD-Type PTC Thermistor as a Function of the Heat Treatment Conditions (적층 SMD형 PTC 써미스터의 열처리 조건에 따른 PTCR 특성 변화)

  • Lee, Mi-Jai;Jang, Jae-Woon;Lim, Tae-Young;Park, Seong-Chul;Song, Jun-Baek;Han, Cheong-Hwa
    • Journal of the Korean Ceramic Society
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    • v.49 no.5
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    • pp.432-437
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    • 2012
  • Electrical properties of the laminated SMD-type PTC thermistor for microcircuit protection were investigated as a function of calcination and sintering temperature. $BaTiO_3$ with $Y_2O_3$ and $MnO_2$ were calcined at 1000 to $1150^{\circ}C$ for 2h and the laminated SMD-type PTC thermistor was sintered at 1350 to $1400^{\circ}C$ for 2h in a reduced atmosphere (1% $H_2/N_2$). Sintered density of the sample was dependent on the calcination and sintering temperature. Electrical properties of the sintered samples were strongly dependent on the densities of samples. For the samples with density below 4.6 g/$cm^3$, the insulator characteristics were observed, while PTC jump characteristics (R150/R30) were disappeared for the sample with density above 5.05 g/$m^3$. Optimal PTC characteristics were obtained for the sintered samples with density of 5.05 g/$m^3$. The laminated SMD-type PTC thermistor prepared by calcination at $1100^{\circ}C$ for 2h and sintering at $1270^{\circ}C$ for 2h showed the room temperature resistivity of $11{\Omega}{\cdot}cm$ and PTC jump characteristics of $10^2$ order.

Quantitative Risk Analysis of a Pervaporation Process for Concentrating Hydrogen Peroxide (과산화수소 농축을 위한 투과증발공정의 정량적 위험성 분석)

  • Jung, Ho Jin;Yoon, Ik Keun;Choi, Soo Hyoung
    • Korean Chemical Engineering Research
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    • v.52 no.6
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    • pp.750-754
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    • 2014
  • Quantitative risk analysis has been performed for a pervaporation process for production of high test peroxide. Potential main accidents are explosion and fire caused by a decomposition reaction. As the target process has a laboratory scale, the consequence is considered to belong to Category 3. An event tree has been developed as a model for occurrence of a decomposition reaction in the target process. The probability functions of the accident causes have been established based on the frequency data of similar events. Using the constructed model, the failure rate has been calculated. The result indicates that additional safety devices are required in order to achieve an acceptable risk level, i.e. an accident frequency less than $10^{-4}/yr$. Therefore, a layer of protection analysis has been applied. As a result, it is suggested to introduce inherently safer design to avoid catalytic reaction, a safety instrumented function to prevent overheating, and a relief system that prevents explosion even if a decomposition reaction occurs. The proposed method is expected to contribute to developing safety management systems for various chemical processes including concentration of hydrogen peroxide.

The Study of the Historic Origin and the Symbolism of Mehndi (멘디의 역사적 기원과 상징성에 대한 연구)

  • Jo, Eun-Young;Yoo, Tai-Soon
    • Fashion & Textile Research Journal
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    • v.6 no.3
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    • pp.297-306
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    • 2004
  • Mehndi, becoming a kind of body fashion in western advanced countries nowadays, is a exquisite, classical fashion form sublimated to traditional faith, medicine and designing art. As one of the cultural arts, especially transmitted by women, a individual tradition of the way how to do the mehndi and the design has been handed down from one culture to another over a thousand of years and it is extensively using in many area, all around world today. Mehndi was used as preparing for special events or celebrations in India, Africa, Central Asia in order to pray for happiness, good luck and calm hart 5000 years ago. Especially, it is concerned with romantic love or a wedding and takes important part of a traditional wedding reception and bride adorning in the culture of Hindu or Islam. In addition to adorning skin, mehndi has various symbols, meaning, function, that is, as a speechless language, in several cultures, it has common meaning such as attraction, protection, celebration. The design of mehndi has been in harmony with the figure, colors, skin types of the dress or the ornament. According to the region, religion, design, mehndi is divided into the design of India and Morocco mostly. Indian design mainly shows flowers and paisley pattern, people widely recognize this design to celebrate and adorn bride in wedding ceremony, still apply mehndi the present time. Moroccan mehndi design, representing North Africa, characterized a bold geometrical figure which stands for belief in living under the protection from supernatural power. Through the understanding of these various meaning, function, symbolism of the design, adorning their body, the current general public use mehndi as not only aesthetic means but also another self expression.