• Title/Summary/Keyword: Prospective Studies

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Structural Relationships Among Parents' and Teachers' Autonomy Support, Children's Basic Psychological Needs, and Children's Participation in Decision-Making (부모와 교사의 자율성 지지, 아동의 기본심리욕구, 아동의 의사결정 참여 간의 구조적 관계)

  • Chae, Eun Young;Lee, Jae Yeon
    • Korean Journal of Child Studies
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    • v.38 no.1
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    • pp.139-151
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    • 2017
  • Objective: The purpose of this study was to explore the structural relationships among parents' and teachers' autonomy support, children's basic psychological needs, and children's participation in decision-making. Methods: The participants were 687 elementary school students (5th and 6th grades) in Seoul and Gyeonggi-do. The data were analyzed using SEM. Results: First, parents' and teachers' autonomy support had a direct effect on children's participation in decision-making. Second, parents' and teachers' autonomy support had an indirect effect on children's participation in decision-making through the children's basic psychological needs. Third, children's basic psychological needs mediated the effects of parents' and teachers's autonomy support and children's participation in decision-making. Conclusion: The findings suggest the importance of the mediating effect of children's basic psychological needs, between parents' and teachers' autonomy support and children's participation in decision-making. The findings can be used as an important basis for prospective research and practices for improving children's participation in decision-making.

A Meta-analysis of Chemotherapy related Cognitive Impairment in Patients with Breast Cancer (유방암 환자에서 화학요법이 인지기능에 미치는 영향에 대한 메타분석)

  • Park, Jin-Hee;Bae, Sun Hyoung
    • Journal of Korean Academy of Nursing
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    • v.42 no.5
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    • pp.644-658
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    • 2012
  • Purpose: The purpose of this study was to evaluate the cognitive effects of chemotherapy in patients with breast cancer. Methods: Using several databases, prospective studies were collected up to August 2011. Of 2,106 publications identified, 12 met the inclusion criteria, and 8 studies were used to estimate the effect size of chemotherapy on cognitive impairment. Results: Twelve studies were done since 2005 and most of the research was performed in Europe or North America. Eight studies were used to generate effect size across the cognitive domains of attention/concentration, verbal and visual memory, executive function, visuospatial skill, language, and subjective cognitive function. Each of the cognitive domains showed small effect sizes (-0.02 ~ -0.26), indicating diminished cognitive function for the chemotherapy group compared with non-chemotherapy groups. Conclusion: Finding suggests that breast cancer patients who undergo chemotherapy may experience mild cognitive decline. Further study is needed to generate knowledge and guideline for interventions to address chemotherapy related cognitive impairment in these patients.

The Effect of Attachment Security on Preschoolers' Perspective Taking: Executive Function as a Mediator (유아의 애착안정성이 조망수용에 미치는 영향: 실행기능의 매개효과를 중심으로)

  • Park, Ha-Yeon;Yi, Soon-Hyung
    • Korean Journal of Child Studies
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    • v.37 no.6
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    • pp.19-33
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    • 2016
  • Objective: This study aimed to examine the prospective links among perspective taking, attachment security, and executive function and the mediating role of executive function on the relationship between attachment security and perspective taking. Methods: The participants included 147 preschoolers living in Gyeonggi. The data-analysis methods included descriptive statistics, independent t-tests, one-way ANOVAs, Pearson's correlation analysis, hierarchical multiple regression analysis, and the Sobel test. Results: First, preschoolers' perspective taking was significantly related to attachment security, and executive function. Furthermore, there was a significant association between attachment security and executive function. As expected, the correlations were positive in all cases. Second, the effects of attachment security on intention and emotion perspective takings were fully mediated by executive function when holding children's age and vocabulary constant. However, executive function did not predict thought perspective taking, whereas attachment security did. Conclusion: Given that parent-child attachment security might play an important role in child cognitive and socio-cognitive development, parents' endeavors to enhance the quality of the attachment relationship could be a fruitful path for preschoolers' developing executive capacities and perspective taking.

Recreational Physical Activity and Risk of Ovarian Cancer: a Meta-analysis

  • Zhou, Li-Min
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.13
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    • pp.5161-5166
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    • 2014
  • Our aim was to access the association between recreational physical activity (RPA) and risk of ovarian cancer (OC). The studies were retrieved from the PubMed and Embase databases up to February 20th, 2014. Risk ratios (OR) and 95% confidence intervals (CI) were used to estimate effect sizes. Random-effects or fixed-effects models were used to pool the data. The trim and fill method was applied for sensitivity analysis. Begg's rank correlation test and Egger's regression asymmetry test were employed to assess the publication bias. A total of 6 studies (435398 participants including 2983 OC patients) were included in this meta-analysis. The overall estimate indicated that there was weakly inverse association between RPA and OC risk (RR=0.90, 95%CI: 0.72-1.12, p=0.335). Meanwhile, for prospective cohort studies, a result consistent with the overall estimate was obtained (RR=1.12, 95% CI: 0.88-1.42, p=0.356). However, for case control studies, the pooled estimate of RR was 0.76 (95%CI: 0.64-0.90, p=0.002), indicating a clear significant association between RPA and OC risk. In addition, the sensitivity analysis indicated a significant link between RPA and risk of OC after removing Lahmann's study (RR=0.80, 95% CI: 0.68-0.93, p=0.004). No significant publication bias was found (Begg's test: p=1.00; Egger's test: p=0.817). In conclusion, our meta-analysis indicated a weakly inverse relationship between RPA and the occurrence of OC.

Traditional Korean Medicine Therapy for Treating Carpal Tunnel Syndrome in Patients with Wrist Pain: A Systematic Review

  • Kim, Jung Hyun;Song, Ho Sueb
    • Journal of Acupuncture Research
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    • v.32 no.2
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    • pp.59-64
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    • 2015
  • Objectives : This study aims to evaluate current clinical evidence of traditional Korean medicine treatment on wrist pain with carpal tunnel syndrome. Methods : Ten Korean databases were searched for prospective clinical trials of traditional Korean medicine therapy on wrist pain with carpal tunnel syndrome from the time of their inception to February, 2015. Studies conducted in Korean, Chinese and English were searched. Risk of bias in included non-randomized controlled trials was assessed by the Cochrane handbook procedure. Results : Four non-randomized controlled trials were included. A high risk of bias was observed in all trials. All of the included studies reported favorable effects being experienced by an intervention group compared to a baseline or control group. Included studies never described any occurrence of adverse events. Conclusions : There is no evidence that traditional Korean medicine treatments are effective for treating wrist pain associated with carpal tunnel syndrome. All of the included studies lacked appropriate methodological qualities and internal validity. Future well-designed clinical trials that evaluate the effects and safety of traditional Korean medicine treatment for patients with carpal tunnel syndrome are needed.

A Study on the Applicability of TMJ Balancing Therapy for the Treatment of Parkinson's Disease (파킨슨병 치료에서 턱관절음양균형요법의 활용 가능성에 대한 소고)

  • Chae, In-Cheol;Lee, Young-Jun;Yoo, Ho-Ryong
    • Journal of TMJ Balancing Medicine
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    • v.11 no.1
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    • pp.12-19
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    • 2021
  • There are many studies that show the association between Parkinson's disease and temporomandibular joint disorder. However, no clinical studies have yet been reported that TMJ Banlancing Therapy (TBT) can treat Parkinson's disease. In this study, the applicability of TBT for the treatment of Parkinson's disease was investigated by reviewing several studies on the factors related to Parkinson's disease and temporomandibular joint disorder and clinical studies of patients with Parkinson's disease using conventional oral appliances and exercises. In summary, it is considered that TBT has a high potential for use in the treatment of Parkinson's disease, but it is thought that prospective clinical research is needed in the future to establish objective evidence related to this.

Anti-Diabetic Medications Do Not Influence Risk of Lung Cancer in Patients with Diabetes Mellitus: a Systematic Review and Meta-analysis

  • Nie, Shu-Ping;Chen, Hui;Zhuang, Mao-Qiang;Lu, Ming
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6863-6869
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    • 2014
  • Objectives: Several preclinical and observational studies have shown that anti-diabetic medications (ADMs) may modify the risk of lung cancer. We performed a systematic review and meta-analysis evaluating the effect of metformin, sulfonylureas (SUs), thiazolidinediones (TZDs), and insulin on the risk of lung cancer in patients with diabetes mellitus (DM). Materials and Methods: We conducted a systematic search of Pubmed and Web of Science, up to August 20, 2013. We also searched the Conference Proceedings Citation Index (CPCI) and China National Knowledge Infrastructure (CNKI) for abstracts from major meetings. Fixed or random effect pooled measures were selected based on heterogeneity among studies, which was evaluated using Q test and the I2 of Higgins and Thompson. Meta-regression was used to explore the sources of between-study heterogeneity. Publication bias was analyzed by Begg's funnel plot and Egger's regression test. Associations were assessed by odds ratios (ORs) with 95% confidence intervals (CIs). Results: A total of 15 studies (11 cohort, 4 case-control) were included in this meta-analysis. In observational studies no significant association between metformin (n=11 studies; adjusted OR=0.99, 95%CI: 0.87-1.12), SUs (n=5 studies; adjusted OR=0.98, 95%CI: 0.79-1.22), or TZDs (n=7 studies; adjusted OR=0.92, 95%CI: 0.75-1.13), insulin (n=6 studies; adjusted OR=1.13, 95%CI: 0.79-1.62) use and risk of developing lung cancer was noted. There was considerable inherent heterogeneity between studies not explained by study design, setting, or location. Conclusions: Meta-analysis of existing studies does not support a protective or harmful association between ADMs use and risk of lung cancer in patients with DM. There was considerable heterogeneity across studies, and future, well-designed, prospective studies would be required for better understanding of any association.

A Review of Research on Self Efficacy Theory Applied to Health Related Behavior (자기효능 이론이 적용된 건강행위 관련 연구의 분석)

  • 구미옥;유재순;권인각;김혜원;이은옥
    • Journal of Korean Academy of Nursing
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    • v.24 no.2
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    • pp.278-302
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    • 1994
  • This article reviewed and analyzed 39 studies on self efficacy theory applied to health related behavior. The following analysis was done : 1) study subjects 2) measurement tools 3) analysis according to the type of research design(intervention re-search, explanatory research). Some findings are summarized as follows : The study subjects were both healthy people in various developmental stages and patients with various illnesses. The health related behaviors examined in the studies were also various including exercise, smoking cessation, self care behaviors, etc. The measurement of self efficacy was done with specific tools in most studies. In the tools, activities that measured the health behavior domain were listed according to increasing difficulty or contexual arrangement or in combination of both of them The analysis of 17 intervention research studies showed that generally the intervention program increased the self efficacy level of subjects and then the increased strongly self efficacy influenced behavioral changes. Most studies used more than one intervention method for increasing the self efficacy level. these were derived from sources of self efficacy suggested by Bandura. The analysis of 21 explanatory research studies showed that self efficacy strongly influenced behavior change and persistence. The major independent variable to affect the self efficacy was performance accomplishment in the past. Self efficacy explained more of the variance in health related behavior when it was applied with the variables in the health belief model, health promotion model, and reasoned action theory. On the basis of the above findings, the following suggestions are made : 1. For a desirable research design, self efficacy should be the intervening variable. That is, desirable designs would include intervention-self efficacy-behavior in intervention research studies and antecedent-self efficacy-behavior in explanatory research studies. 2. More prospective, longitudinal studies are needed to test the effect of self efficacy on persistence in health related behavior. 3. Studies comparing the effects of intervention methods are needed for each health related behavior, subject group, and context. 4. It is necessary to develop a reliable, valid measurement tool for self efficacy for each health related behavior. 5. Studies to differenciate the effect of self efficacy from that of outcome expectation on the health related behavior are necessary. 6. The antecedents of self efficacy should be investigated further.

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Systemic Review of Clinical Studies about Oriental Medical Treatment of Cancer in Korea (국내에 보고된 한국 한의학의 암치료 임상연구에 대한 계통적 고찰)

  • Park, Bong-Ky;Lee, Jong-Hoon;Cho, Chong-Kwan;Shin, Hyun-Kyu;Eom, Seok-Ki;Yoo, Hwa-Seung
    • The Journal of Internal Korean Medicine
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    • v.29 no.4
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    • pp.1061-1074
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    • 2008
  • Objectives : Recently, the number of cancer patients who use complementary and alternative medicine (CAM), including oriental medicine, are increasing. Also, evidence for efficacy and safety of cancer CAM is reported continuously. This study was designed to evaluate the quality of the published papers for clinical studies about oriental medical cancer treatment in Korea. Methods : We searched for clinical research papers on the websites of the Korean oriental medical society and subsidiary academies, Korean traditional knowledge portal. Koreanstudies information service system (KISS), etc. We used the reference words 'cancer', 'malignant tumor', 'leukemia', 'lymphoma', 'multiple myeloma', 'melanoma', etc, We then chose studies that had been presented between 1991 and 2008 and analyzed them by publication year, design, cancer type, intervention, subject and journal. Results : There were 86 clinical research papers that were published between 1991 and 2008. The number of clinical studies has increased in a time-dependent manner. Case reports and case series studies account for 78% of total clinical research. Studies of lung cancer account for 17%. Studies of cancer-related symptoms of cancer patients account for 38%. Studies of Hang-Am-Dan account for 33%. Studies published in the journal of the Korean Society of Oriental Internal Medicine account for 35%. Conclusion : The clinical research papers about oriental medicine are increasing over time, but most of the studies are retrospective case reports or case series. Well-designed and prospective clinical trials would be recommended to provide more reliable evidence.

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Outcomes of dental implant treatment in patients with generalized aggressive periodontitis: a systematic review

  • Kim, Kyoung-Kyu;Sung, Hun-Mo
    • The Journal of Advanced Prosthodontics
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    • v.4 no.4
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    • pp.210-217
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    • 2012
  • PURPOSE. The purpose of this study was to analyze the current literatures and to assess outcomes of implant treatment in patients with generalized aggressive periodontitis. MATERIALS AND METHODS. Studies considered for inclusion were searched in Pub-Med. The literature search for studies published in English between 2000 and 2012 was performed. Our findings included literature assessing implant treatment in patients with a history of generalized aggressive periodontitis (GAP). All studies were screened according to inclusion criteria. The outcome measures were survival rate of superstructures, marginal bone loss around implant and survival rate of implants. All studies were divided into two follow-up period: short term study (< 5 years) and long term study (${\geq}5$ years). RESULTS. Seven prospective studies were selected, including four short-term and three long-term studies. The survival rates of the superstructures were generally high in patients with GAP, i.e. 95.9-100%. Marginal bone loss around implant in patients with GAP as compared with implants in patients with chronic periodontitis or periodontally healthy patients was not significantly greater in short term studies but was significantly greater in long term studies. In short term studies, the survival rates of implants were between 97.4% and 100% in patients with GAP-associated tooth loss, except one study. The survival rates of implants were between 83.3% and 96% in patients with GAP in long term studies. CONCLUSION. Implant treatment in patients with GAP is not contraindicated provided that adequate infection control and an individualized maintenance program are assured.