• 제목/요약/키워드: Prospective Studies

검색결과 846건 처리시간 0.026초

한국에서 발생한 침구요법의 이상반응 보고사례에 대한 체계적 분석 (Systematic Review of Adverse Events Related to Acupuncture and Moxibustion in Korea)

  • 박지연;김송이;채윤병;채한;구성태;김승태;신상우;장인수;이상훈;인창식;이혜정;박히준
    • 대한한의학회지
    • /
    • 제31권2호
    • /
    • pp.78-90
    • /
    • 2010
  • Objective: The aim of this study was to review case reports about adverse events of acupuncture or moxibustion treatments in Korea. Methods: Electronic literature searches were performed for adverse events of acupuncture or moxibustion treatments in Korea up to October 2009. Results: Sixteen case reports or case series were retrieved in total. Among them, 10 were reporting about acupuncture, 5 about pharmaco-acupuncture (3 bee venom acupuncture and 2 others), and 1 was reporting about moxibustion treatment. The incidence of adverse effects couldn't be proven due to the lack of prospective studies. Conclusion: Acupuncture treatment seems to be one of the safer forms of medical interventions, when performed by skilled Korean medical doctors. However, prospective studies are necessary to reach conclusions about safety. In addition, a system for collecting and managing adverse effects of Korean medical interventions as well as a reeducation system for clinicians is needed.

Depressive Symptoms on the Geriatric Depression Scale and Suicide Deaths in Older Middle-aged Men: A Prospective Cohort Study

  • Yi, Sang-Wook
    • Journal of Preventive Medicine and Public Health
    • /
    • 제49권3호
    • /
    • pp.176-182
    • /
    • 2016
  • Objectives: Prospective evaluations of the associations between depressive symptoms and suicide deaths have been mainly performed in high-risk populations, such as individuals with psychiatric disorders or histories of self-harm. The purpose of this study was to prospectively examine whether more severe depressive symptoms assessed using the Geriatric Depression Scale (GDS) were associated with a greater risk of death from suicide in a general-risk population. Methods: A total of 113 478 men from the Korean Veterans Health Study (mean age, 58.9 years) who participated in a postal survey in 2004 were followed up for suicide mortality until 2010. Results: Over 6.4 years of follow-up, 400 men died by suicide (56.7 deaths per 100 000 person-years). More severe depressive symptoms were associated with greater risk of suicide death (p for trend <0.001). The unadjusted hazard ratios (HRs) in comparison to the absence of depression were 2.18 for mild depression, 2.13 for moderate depression, 3.33 for severe depression, and 3.67 for extreme depression. After adjusting for potential confounders, men with a potential depressive disorder had an approximate 90% higher mortality from suicide (adjusted HR, 1.92; 95% confidence interval [CI], 1.38 to 2.68; p<0.001) than men without depression. Each five-point increase in the GDS score was associated with a higher risk of death by suicide (adjusted HR, 1.22; p<0.001). The value of the area under the receiver operating characteristics curve of GDS scores for suicide deaths was 0.61 (95% CI, 0.58 to 0.64). Conclusions: Depressive symptoms assessed using the GDS were found to be a strong independent predictor of future suicide. However, the estimate of relative risk was weaker than would be expected based on retrospective psychological autopsy studies.

추적관찰에 의한 일개 전문계 남자고등학생의 흡연 예측 인자 (Predictors of Current Smoking among Male Students in a Technical High School: A Prospective Study)

  • 김종연;박순우
    • Journal of Preventive Medicine and Public Health
    • /
    • 제42권1호
    • /
    • pp.59-66
    • /
    • 2009
  • Objectives : This study was performed using a longitudinal approach to explore the predictors for current smoking among male high school students. Methods : Baseline data was collected in May 2004 through a self-administrated questionnaire completed by 607 male students in a technical high school in Daegu city, Korea. Subsequently, their smoking behaviors were followed one year after. Among the 544 followed participants, data for 439 non-smokers in the first year was used in longitudinal analysis. Current smokers were defined as those respondents who had smoked one or more cigarettes within the 30 days preceding the survey. Several potential predictors for smoking were investigated including smoking history(never, experimental, former smoker), sociodemographic factors, environmental factors, attitudes toward smoking, and behavioral factors. Logistic regression was used to predict smoking with SPSS ver. 12.0. Results : According to multiple logistic regression analysis, those students who were more likely to smoke after one year were former smokers(OR: 2.12, 95% CI=1.01-4.44), current drinkers(OR: 2.55, 95% CI=1.33-4.89), who had four or five smokers among five best friends(OR: 3.43. 95% CI=1.14-10.30). In addition, those who had smokers among family members besides parents or siblings(OR: 1.66, 95% CI=0.92-2.98), exhibited a high level of subjective stress(OR: 1.77, 95% CI=0.96-3.26), or had a very good relationship with friends(OR: 1.93, 95% CI=0.99-3.75) were also more likely to smoke albeit with marginal statistical significance(p<0.1). Conclusions : A smoking prevention program aimed at high school students may be more effective with due consideration of the predictors highlighted in this study. However, further studies with larger sample size and various target populations are necessary to find potential predictors not found in this study but suggested in other longitudinal studies.

폐경 후 여성의 대사증후군 지표와 영양소 섭취에 대한 비교 융합연구 : 2010~2012 국민건강영양조사자료 이용 (Comparison of metabolic syndrome indicators and nutrient intakes in postmenopausal women : from the Korean National Health and Nutrition Examination Survey, 2010~2012)

  • 황효정;최연정
    • 한국융합학회논문지
    • /
    • 제10권9호
    • /
    • pp.99-110
    • /
    • 2019
  • 본 연구는 제 5기 국민건강영양조사(2010~2012) 결과를 바탕으로 폐경여성의 대사증후군 지표에 따른 영양소 섭취를 비교 조사하였다. 조기폐경 여성 214명과 일반폐경 여성 2,545명을 분류하였으며, 폐경여성의 영양섭취에서 비만인 경우 레티놀 섭취와의 연관을 나타내고 있음을 확인하였고, 당뇨인 경우 리보플라빈 섭취량에 있어서 유의함을 확인하였다. 본 연구 결과 폐경여성에서 레티놀과 리보플라빈, 조섬유, 칼슘 및 나트륨 등의 미량영양소가 대사증후군 위험과 관련성이 있음을 보였는데, 추후 대규모 전향적 연구가 실시되어 각 영양소 섭취량과 폐경 후 대사증후군의 인과관계를 더욱 명확히 규명할 필요가 있을 것이라 사료된다.

데이터형 전자기록을 위한 출처 개념 모델 개발 방향 (Toward Developing a Provenance Conceptual Model for Data-driven Electronic Records)

  • 현문수
    • 기록학연구
    • /
    • 제79호
    • /
    • pp.305-341
    • /
    • 2024
  • 이 연구는 디지털 환경에서 데이터가 중심이 되는 전자기록의 출처에 새롭게 접근하기 위해, 데이터 출처 개념과 출처 모델을 검토하고 수용하여, 어떻게 전자기록을 대상으로 새롭게 출처 개념을 적용할 수 있을지의 가능성을 살펴보았다. 이어서 데이터 중심의 전자기록을 대상으로 한 출처 표현 모델을 개발하기 위해 기초 연구를 진행하였다. 특히 소급형 출처와 전망형 출처 개념으로 전환할 것과, 기록관리 메타데이터와는 별개의 모델을 통해 출처를 표현하고 기록과 연결할 수 있는 모델을 개발할 것을 제안하였다. 기록과 동적 관계를 맺으면서도 독립적으로 출처를 표현할 수 있는 모델을 개발할 수 있다면, 오히려 기록의 유동성을 보장할 수 있으면서도, 기록의 속성과 이를 지원할 출처의 역할을 더 충실히 수행할 수 있을 것이다. 결국, 이 연구가 제안한 기본적인 모델 개발 방향을 수용하는 출처 모델은 기록의 고정성과 활동의 재현성, 재현의 신빙성을 뒷받침할 수 있을 것이며, 디지털환경에서 적합한 출처 모델로서 역할을 할 수 있을 것이다.

내분비질환에 영향을 미치는 심리적 요인 (Psychological Factors Affecting Endocrine Disease)

  • 조숙행
    • 정신신체의학
    • /
    • 제6권2호
    • /
    • pp.221-227
    • /
    • 1998
  • Although there has been a considerable research in psychoneuroendocrinology, particularly in relation to the biology of mood disorders, there has been a paucity of research regarding the effects of psychological factors on endocrine diseases. Of the existing literature, the most research is focused on diabetes mellitus, graves' disease. Especially diabetes appears to be the only endocrine disease that has been the focus of recent research studies. Most of the studies had retrospective designs or several methodological flaw. There has been no consistent results demonstrating that psychological factors affect the onset of diabetes mellitus. Several studies have suggested that psychological factors affect the course of diabetes. A small number of studies showed some evidence that psychological stress was associated with changes in glucose regulation in a subset of diabetic patients. There was also evidence to suggest that some temperament and coping skill influence glycemic control in child, adolescent diabetics. Studies of behavioral or psychosocial intervention on diabetic control have been small and have produced mixed results. There was a few controlled study suggested that stressful life events might be a causal role in Cushing's disease and Graves'disease, but there is no presently sufficient evidence to suggest that psychological factors affect the onset and the course of Cushing's disease and Graves' disease. In future, there is need for a well-designed biopsychosocial research with prospective designs, well defined patient population and control groups to study the relationship between psychological factors and endocrine diseases.

  • PDF

Survival rates against fracture of endodontically treated posterior teeth restored with full-coverage crowns or resin composite restorations: a systematic review

  • Suksaphar, Warattama;Banomyong, Danuchit;Jirathanyanatt, Titalee;Ngoenwiwatkul, Yaowaluk
    • Restorative Dentistry and Endodontics
    • /
    • 제42권3호
    • /
    • pp.157-167
    • /
    • 2017
  • This systematic review aims to summarize the current clinical studies that investigated survival rates against fracture of endodontically treated posterior teeth restored with crowns or resin composite restorations. Literature search were performed using keywords. Publications from 1980 to 2016 were searched in PubMed, ScienceDirect, ISI Web of SCIENCE, MEDLINE, and SCOPUS. Included studies were selected based on inclusion and exclusion criteria. Three clinical studies were included: 1 randomized controlled trial and 1 prospective and 1 retrospective cohort studies. Pooled survival rates ranged from 94%-100% and 91.9%-100% for crowns and resin composite, respectively. The majority of teeth had no more than 3 surface loss of tooth structure. The studies included were heterogeneous, and were not appropriate for further meta-analysis. Current evidence suggested that the survival rates against the fracture of endodontically treated posterior teeth restored with crowns or resin composites were not significantly different in the teeth with minimum to moderate loss of tooth structure.

일개 대학병원의 환자군별 진료서비스 변이와 포괄수가제 적용에 따른 진료수익 변화 (Studies on the variations of hospital use and the changes in hospital revenues of 10 KDRGs under the PPS)

  • 전기홍;송미숙
    • 보건행정학회지
    • /
    • 제7권1호
    • /
    • pp.100-124
    • /
    • 1997
  • In order to suggest the strategies for participation in the PPS(Prospective Payment System), analyses were performed based on variations in utilization pattern and changes in revenues of hospitals in 10 selected KDRGs. The data was collected from the claims data of a tertiary hospital in Kyunggido from September 1, 1995 to August 31, 1996. The studies consisted of 1, 718 inpatients diagnosed for lens procedures, tonsilectomy &/or adenoidectomy, appendectomy with complicated principal diagnosis, Cesarean section, or vaginal delivery without any complications. The resources used in each KDRG were measured including average length of stay, total charges, number of orders, intensity of medical services, frequencies of medical services, the rate of non-reimbursable charges, and the rate of non-reimbursable orders. Then, the changes in hopital revenues due to the composition of medical fee schedules under the PPS were estimated as follows: 1) The variations in average lenght of stay, total charges, number of orders, the intensity of medical services, the frequency of medical services, the rate of non-reimbursable charges, and the rate of non-reimbursable orders among the 10 KDRGs were comparatively small. 2) The average lenght of stay was the longest(6.0 days) for appendectomy with complicated principal diagnosis, while it was the shortest(2.1 days) for two vaginal deliveries. Statistically differences existed in the average length of stay among physicians and among the dates of admission in several KDRGs. 3) The total charges were the highest for lens procedures(1, 716, 000 won), while the lowest charges were for two vaginal deliveries(558, 000 won). Statistically differences in the total charges were found among physicians in several KDRGs: however, there were no differences with the dates of admission. 4) The number of orders was the greatest(155) for appendectomy with complicated principal diagnosis, while it was the smallest(75) for the two vaginal deliveries. Statistical differences in the number of orders did not exist among physicians in the KDRGs. 5) Significant differences were found in the intensity of medical services, and in the frequency of medical services among physicians in the KDRGs. 6) The rate of non-reimbursable charges for each KDRG was not related to the rate of non-reimbursable orders. The rate of non-reimbursable orders was the highest(36.0%) for lens procedures, while the lowest rate(11.6%) was for appendectomy with complicated principal diagnosis. The rate of non-reimbursable charges was the highest(39.4-39.7%) for vaginal deliveries, while the lowest rate(13.1%) was for tonsillectomy &/or adenoidectomy(<17 ages). 7) If the physician's practicing style were not change under the PPS, the hospital revenuses could be increased by 10%, and the portion of patient payment could be decreased by 1.4-22.4%. However, the non-reimbursable charges for showed little change between two reimbursement systems. Based upon the above findings, this hospital could be eligible for participation in the PPS(Prospective Payment Systm). However, the process of diagnosis and treatment should be standardized, inentifying methods to reduce cost and to assure quality of medical care. Furthermore, consideration should be given to finding ways to increase patient volume.

  • PDF

양극성 장애 환자에서 불안이 질병 경과에 미치는 영향 : 전향적 추적관찰에 대한 중간분석 (Anxiety Hastened Depressive Recurrence in Bipolar Disorder : An Interim Analysis of Prospective Follow-Up Study)

  • 김수정;김소정;송혜현;이원혜;전명욱;남윤영;박동연
    • 생물정신의학
    • /
    • 제28권1호
    • /
    • pp.13-22
    • /
    • 2021
  • Objectives Despite growing attention to anxiety in bipolar disorder (BD), little research has assessed anxiety symptoms in the course of BD. The current prospective follow-up study examines the influence of subjectively and objectively measured anxiety symptoms on the course of BD. Methods A total of 49 patients with BD were followed-up prospectively for average of one year at an average of four months interval. The Korean version of the Beck Anxiety Inventory (K-BAI), the Hamilton Anxiety Rating Scale, heart rate variability (HRV) were used to measure anxiety subjectively, objectively and physiologically. Participants were divided into high and low anxiety groups based on their K-BAI scores. Kaplan-Meier survival analysis was performed to compare the recurrence of mood episode, suicide attempt, emergency room visit, and psychiatric hospitalization between two groups. Mediators were investigated with Cox proportional hazards models. Results Compared to the low anxiety group, the high anxiety group reported significantly higher impulsiveness (p = 0.016) and lower high frequency component on HRV (p = 0.007) after controlling for severity of BD. Regarding survival analysis, the high anxiety group showed hastened depressive episode recurrence (p = 0.048) and suicidal ideation was the mediator of the hazard ratio (HR) 1.089 (p = 0.029) in the Cox model. Moreover, the high anxiety group showed a tendency of accelerated suicide attempt (p = 0.12) and impulsivity was the risk factor of suicide attempt (HR = 1.089, p = 0.036). Conclusions This interim analysis of prospective study suggests that high anxiety level in BD may anticipate unfavorable course. Further studies are needed to understand the multifactorial mechanism of anxious bipolar patients.

A prospective multicenter clinical study on the efficiency of detachable ball- and spring-retained implant prosthesis

  • Min-Jung Kim;Won-Tak Cho;Su-Hyun Hwang;Ji-Hyeon Bae;Eun-Bin Bae;June-Sung Shim;Jong-Eun Kim;Chang-Mo Jeong;Jung-Bo Huh
    • The Journal of Advanced Prosthodontics
    • /
    • 제15권4호
    • /
    • pp.202-213
    • /
    • 2023
  • PURPOSE. This prospective clinical study was conducted to evaluate the clinical usefulness of the freely detachable zirconia ball- and spring-retained implant prosthesis (BSRP) through a comparative analysis of screw- and cement-retained implant prosthesis (SCRP). MATERIALS AND METHODS. A multi-center, randomized, prospective clinical study evaluating the clinical usefulness of the detachable zirconia ball- and spring-retained implant prostheses was conducted. Sixty-four implant prostheses in 64 patients were examined. Periodic observational studies were conducted at 0, 3, 6, and 12 months after delivery of the implant prosthesis. Factors such as implant success rate, marginal bone resorption, periodontal pocket depth, plaque and bleeding index, and prosthetic complications were evaluated, respectively. RESULTS. During the 1-year observation period, all implants survived without functional problems and clinical mobility, showing a 100% implant success rate. Marginal bone resorption was significantly higher in the SCRP group than in the BSRP group only at the time of implant prosthesis delivery (P = .043). In all observation periods, periodontal pocket depth was slightly higher in the BSRP group than in the SCRP group, but there was no significant difference (P > .05). The modified plaque index (mPI) scores of both groups were moderate. Higher ratio of a score 2 in modified sulcus bleeding index (mBI) was observed in the BSRP group in the 6- and 12-months observation. CONCLUSION. Within the limitations of this study, the newly developed zirconia ball- and spring-retained implant prosthesis could be considered as an applicable and predictable treatment method along with the existing screw- and cement-retained prosthesis.