• Title/Summary/Keyword: Propyl gallate

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Immune Suppression and Stimulation of Antioxidants -Effect of Propyl gallate on Murine Humoral Immune Functions and Methemoglobin Content- (한산화제의 면역억제 및 항진 연구 - 항산화제인 Propyl gallate가 체액성 면역기능과 Aniline 유도 Methemoglobin 함량에 미치는 영향 -)

  • 유충규;황미경
    • Journal of Food Hygiene and Safety
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    • v.3 no.2
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    • pp.83-88
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    • 1988
  • Propyl gallate used as an antioxidant was examined for its effects on murine Immune system and metbemoglobin content treated with anillne. As immunotoxicology assay parameters, we adopted circulating leukocytes and immunoorgan weights for pathtoxicology, IgM plaque forming cells and Artbus reaction for humoral immunity. Propyl gallate's effects were observed as follows; 1. Propyl gallate decreased circulating leukocyte counts, dose dependently. 2. Relative immunoorgan weigbts were not affected. 3. Propyl gallate diminisbed IgM PFCs/spleen cell and IgM PFCs/spleen. 4. Propyl gallate decreased Arthus reaction. 5. Propyl gallate did not affect metbemogiobin content treated wltb aniIIne.

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Immune Suppression and Stimulation of Antioxidants II -Effect of Propyl gallate on Murine Cell Mediated Immune Functions- (항산화제의 면역억제 및 항진연구 II - 항산화제인 Propyl gallate가 세포 면역기능에 미치는 영향 -)

  • 유충규;황미경
    • Journal of Food Hygiene and Safety
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    • v.5 no.1
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    • pp.41-48
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    • 1990
  • Propyl gallate used as an antioxidant was examined for its effects on murine immune system. As immunotoxicology assay parameters, we adopted circulating leukocytes and immunoorgan weights for pathotoxicology, delayed hypersensitivity and colloidal carbon clearance for cell mediated immuntity. Propyl gallate's effects were observed as follows; 1) Propyl gallate decreased circulating leukocyte counts, dose dependently. 2) Propyl gallate decreased delayed hypersensitivity reaction. 3) Phagocytic index were similar in the test and control groups.

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Optophysical Properties of Hydrogel Ophthalmic Lenses Containing Gallate Group (Gallate group이 포함된 친수성 안의료용 렌즈의 광물리적 특성)

  • Park, Se-Young;Sung, A-Young
    • Journal of the Korean Chemical Society
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    • v.56 no.6
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    • pp.725-730
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    • 2012
  • HEMA (2-hydroxyethyl methacrylate), EGDMA (ethylene glycol dimethacrylate; cross-linker), MMA (methyl methacrylate) and AA (acrylic acid) were copolymerized with ethyl gallate and propyl gallate as additives in the presence of AIBN (2,2'-azobisisobutyronitrile; initiator). The measurement of physical properties of the produced copolymers exhibited that refractive index, water content, visible transmittance, tensile strength, and contact angle were in the range of 1.433-1.435, 38.71-38.99%, 85.4-88.8%, 0.2468-0.2740 kgf and $49.77-36.29^{\circ}$, respectively. The transmittances of the copolymers were measured to be in the range of 49.0-7.4% and 71.0-43.4% for UV-B and UV-A, respectively, indicating that the copolymers have UV-blocking effect. The produced copolymers containing ethyl gallate and propyl gallate satisfied the basic physical properties required for the fabrication of hydrogel contact lenses. The copolymers showed an increase of wettability and UV-blocking effects while having no significant change in water content compared to the gallate-free copolymers.

Antimicrobial Activities of Alkyl Gallates Alone and in Combination with Antibiotics Against the Fish Pathogenic Bacteria Edwardsiella tarda and Vibrio anguillarum (알킬갈레이트 유도체의 어병세균 Edwardsiella tarda와 Vibrio anguillarum에 대한 항균활성 및 항생제와의 병용효과)

  • Kang, So-Young;Kang, Ji-Young;Kim, Su-Yeon;Kim, Do-Hyung;Oh, Myung-Joo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.41 no.3
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    • pp.188-192
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    • 2008
  • Methyl gallate isolated from bark of the tree Rhus verniciflua Stokes has significant antimicrobial activity against the fish pathogenic bacteria Edwardsiella tarda and Vibrio anguillarum. To evaluate the antimicrobial activity of gallate derivatives, eight alkyl gallates were tested. Ethyl gallate and propyl gallate had the highest activities, with MICs of $15.6-31.3{\mu}g/mL$ against E. tarda. For V. anguillarum, propyl gallate and butyl gallate were highly effective, with MICs of $7.81-31.3{\mu}g/mL$. When used in combination with antibiotics, methyl gallate exhibited synergistic effects with oxytetracycline against E. tarda and with norfloxacin against V. anguillarum. These results suggest that short-chain alkyl gallates can be used as alternatives to antibiotics against the fish pathogenic bacteria.

Inhibition of Gap Junctional Intercellular Communication in Rat Liver Epithelial Cells Induced by BHT and Propyl Gallate (간상피세포에서 BHT와 propyl gallate에 의한 gap junctional intercellular communication 억제 효과)

  • Kim, Ji-Sun;Kim, Sung-Ran;Ahn, Ji-Yun;Ha, Tae-Youl;Kang, Kyoung-Sun;Kim, Sun-A
    • Korean Journal of Food Science and Technology
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    • v.39 no.5
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    • pp.558-563
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    • 2007
  • This study was conducted to analyze the cytotoxic effects of butylated hydroxytoluene (BHT) and propyl gallate (PG) in WB-F344 rat liver epithelial cells. Here we measured the inhibition level of gap junctional intercellular communication (GJIC) and elucidated the relationships between GJIC and mitogen-activated protein kinases (MAPKs) such as ERK, JNK, and p38. The cytotoxicities of BHT and PG appeared at concentrations of 1.0mM and 0.25mM, respectively, in the WB-F344 cells; and GJIC inhibition, which was analyzed by a scrape-loading/dye transfer assay and Western blotting analysis, appeared at 0.6mM for BHT and 0.1mM for PG, respectively. Also, the phosphorylations of Cx43, ERK, JNK, and p38 increased in dose-dependent manners. This suggests that BHT and PG treatments inhibited GJIC by the phosphorylation of MAPKs prior to cell damage.

Effect of propyl gallate on the properties of regenerated cellulose fiber spun from NMMO dope system (Propyl gallate가 NMMO계에서 제조된 셀룰로오스 섬유의 물성에 미치는 영향)

  • Lee, Soo;Lee, Sang-Won;Lee, Hyang-Yeol
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.4
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    • pp.508-514
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    • 2010
  • Regenerated cellulose fibers were prepared from three pulps containing different degree of polymerization(DP) and $\alpha$-cellulose contents by dry-jet wet spinning technique with cellulose dope in N-methylmorpholin N-oxide (NMMO). The effect of antioxidant, n-propyl gallate (PG) on the properties of different regenerated celluloses was studied using X-ray diffraction, copper number calculation, and viscometry. The degradaqtion of regenerated cellulose from pulp containing higher DP and lower $\alpha$-cellulose content was occurred more seriously. The tensile strength and initial modulus of regenerated cellulose fiber obtained from NMMO dope with PG were higher than those of fiber obtained from NMMO dope without PG. All fibers showed the round shape cross section and typical cellulose II crystalline structure.

A study on the Property of Oxidation Stability in Biodiesel by the Additives (첨가제에 따른 바이오디젤 산화안정 특성 연구)

  • Kang, Hyung-Kyu;Song, Ho-Yong;Doe, Jin-Woo;Park, Soo-Youl;Na, Byung-Ki
    • Journal of the Korean Applied Science and Technology
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    • v.32 no.4
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    • pp.639-648
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    • 2015
  • Some materials of fatty acids in the biodiesel affect the physical/chemical properties like density, kinematic viscosity, total acid number and oxidation stability by forming an organic fatty acid in combination with oxygen in the air. To solve the problem of the oxidative stability of biodiesel, various kinds of antioxidant has added and analyze the characteristics of the physical/chemical property changes by the addition of antioxidant. Oxidation stability increased by the increase of additives content. The TBHQ among the seven kinds of the additives showed the best performance. Also, 4 kinds of additives like propyl gallate, butyl-amine and pyrogallo has showed above 10 hr of oxidation stability at the addition of 500 ppm. In case of pyrogallo, this is not appropriate as an additive to suitable quality standards of total acid number. TBHA, DTBHQ of hydroquinone was satisfied with the quality standard of oxidation stability but the target of this research(above 10 hr) did not satisfied with oxidation stability. Propyl gallate is also a suitable at the quality standards of total acid number but it was shown not to be an appropriate to the additives due to increasing the total acid number by increasing of the content of additives at the addition of 500 ppm.

Antioxidative Effects of various Antioxidants on the Soybean Oil (대두유에 있어서 항산화제 종류에 따른 항산화력의 비교)

  • Yoon, Soo-Hong;Kim, Jong-Won
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.17 no.1
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    • pp.19-23
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    • 1988
  • The natural antioxidants such as ${\alpha}-tocopherol$, NDGA, proply gallate and sesamol, and synthetic antioxidants, BHA were used to compare antioxidative effects of those antioxidants from tile physico-chemical properties and fatty acid composition changes in the soybean oil during storage. The oils were stored at $25^{\circ}C$ for 2 weeks after heat treatment. Natural antioxidants were less effective than BHA but effect of ${\alpha}-tocopherol$ was very similar to that of BHA. The order of antioxidative effect was BHA, ${\alpha}-tocopherol$, NDCA propyl gallate and sesamol. The relative contents of linoleic acid and linolenic acid was decreased as the degree of oxidative rancidity was increased. whereas content of oleic acid and palmitic acid was increased. The content of linoleic acid and linolenic acid did not decreased by addition of BHA and ${\alpha}-tocopherol$.

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Photostability of Anthocyanin Extracted from Purple-Fleshed Sweet Potato (자색고구마에서 추출한 anthocyanin의 광안정성)

  • Rhim, Jong-Whan;Lee, Jang-Wook
    • Korean Journal of Food Science and Technology
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    • v.34 no.2
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    • pp.346-349
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    • 2002
  • Effect of EDTA, gallic acid, phosphoric acid, propyl gallate and sodium ascorbate on the photostability of anthocyanin extracted from purple-fleshed sweet potato were investigated by measuring the absorbance at 530 nm with a spectrophotometer. White light of 20,000 lux was used to illuminate the pigment and the temperature was $20^{\circ}C$. EDTA and sodium ascorbate were more effective in improving the photostability of the pigment when added at least 100 or 1,000 ppm, respectively.