• Journal of Preventive Medicine and Public Health
• /
• 제50권3호
• /
• pp.210-216
• /
• 2017

Objectives: One way to prevent deaths due to rabies is the timely utilization of post-exposure prophylaxis (PEP). Therefore, in addition to an understanding of the epidemiological distribution of animal bites, it is necessary to explore the factors leading to delays in PEP initiation. Methods: This cross-sectional study was conducted in Iran in 2011, and included 7097 cases of animal bites recorded at the Rabies Treatment Center of the Shiraz University of Medical Sciences using the census method. Logistic regression was used to identify factors associated with delays in PEP. Results: Among the patients studied, 5387 (75.9%) were males. The prevalence of animal bites in Fars province was 154.4 per 100 000 people. Dogs were the most frequent source of exposure (67.1%), and the most common bitten part of the body was the hands (45.5%). A delay in the initiation of PEP was found among 6.8% of the studied subjects. This delay was more likely in housewives (odds ratio [OR], 4.66; 95% confidence interval [CI], 2.12 to 10.23) and less likely in people with deep wounds (OR, 0.65; 95% CI, 0.43 to 0.97). Conclusions: Although all animal bite victims received complete PEP, in some cases, there were delays. Further, the type of animal involved, the depth of the bite, and the patient's occupation were the major factors associated with a delay in the initiation of PEP for rabies prevention.

• 치위생과학회지
• /
• 제4권1호
• /
• pp.33-38
• /
• 2004

The purpose of this study was to analyzes the Job of Dental Hygienists in Dental (Clinics) Hospitals the Capital region. This study analyzes the degree of job importance and education-training need about and task, task according to work place and work age. The results are as follows : (1) Job importance of dental hygienists were order 'photographing in Dental Radiology', 'Management of Dental clinic', 'Oral prophylaxis', in case education-training need was order 'dental health insurance', 'Oral prophylaxis', 'Management of Dental clinic'. duty more than 5.0 of job importance and education-training need was as 'dental health education', 'Oral prophylaxis', 'preventive dental treatment', 'dental assistance (cooperation)', 'photographing in Dental Radiology', 'dental health insurance', 'Management of Dental clinic', Duty of practice centering in Dental (Clinics) Hospitals except 'Public oral health'. (2) Job importance and education-training need of task increased most of job importance in proportion to education-training need. (3) No significantly between dental hospital hygienist and dental clinic hygienist difference of job importance and education-training need according to work place. but 'Management of Dental clinic' and 'dental health insurance' of dental hospital hygienist lower than dental clinic hygienist. (4) The results job importance compare less 3 years to more 3 years of dental hygienists were perceive significantly 'dental health education', 'Public oral health', 'dental health insurance', 'Management of Dental clinic' the other hand, education-training need was perceive significantly 'preventive dental treatment'.

• 치위생과학회지
• /
• 제19권1호
• /
• pp.9-22
• /
• 2019

Background: The purpose of this systematic review was to investigate the effects of topical fluoride gel application on dental caries prevention in the permanent teeth of children and adolescents. Methods: We searched the EMBASE, PubMed, and Cochrane Library databases for randomized controlled trials (RCTs) assessing the effects of self-applied or professionally applied topical fluoride gels in patients <18 years of age; the search was completed on April 1, 2018. All included trials involved an experimental group (fluoride gel application) and a control group (placebo or no treatment). The outcome measures were the D(M)FS and D(M)FT indices, which were compared between the two groups. Review Manager software was used for quantitative synthesis of the final selected articles, and a forest plot was generated via a meta-analysis conducted using a random effects model. Results: The results showed that the D(M)FS and D(M)FT indices were lower in the fluoride application group than in the control group, thus indicating that fluoride gel application was effective in dental caries prevention. We also performed a subgroup analysis to determine whether the effects of fluoride application differed if patients received oral prophylaxis (self or professional) before fluoride gel application. Therefore, the two groups showed slightly larger differences when studies without oral prophylaxis before fluoride gel application were considered; however, the difference was not statistically significant. Conclusion: These findings should be utilized to raise awareness about the caries-prevention effects of topical fluoride application among patients and guardians. Further RCTs should evaluate the effects of fluoride application with or without preceding oral prophylaxis, and appropriate fluoride application guidelines should be developed to maximize the effects of fluoride application in clinical practice.

• Urogenital Tract Infection
• /
• 제13권3호
• /
• pp.72-78
• /
• 2018

Purpose: This retrospective study was undertaken to investigate whether increasing amikacin dosage for ciprofloxacin prophylaxis in patients with fluoroquinolone (FQ)-resistant rectal flora reduce infectious complications after transrectal ultrasound-guided prostate biopsy (TRUSPB). Materials and Methods: A total of 430 patients with FQ-resistant rectal flora based on rectal swab cultures were divided into two groups. Patients in both groups were administered ciprofloxacin (400 mg, intravenous [IV], twice daily) on the same day as TRUSPB and one day after biopsy. However, whereas group 1 patients (n=202) were administered a single injection of amikacin (1 g, IV) one hour before TRUSPB, patients in group 2 (n=228) were administered two injections of amikacin (1 g, IV) before one hour TRUSPB and again on the day after TRUSPB. Results: Of the 430 study subjects, 129 (30.0%) showed extended-spectrum beta-lactamase (ESBL) positivity. The overall incidence rate of infectious complications was 2.8% (12/430). Infectious complication rates were 4.0% (8/202) in group 1 and 1.3% (3/228) in group 2 (p=0.075). Urinary tract infection and acute prostatitis were more frequent in group 1 (3.5% vs. 0.4%, p=0.029). Infectious complication rates in ESBL negative patients were 3.4% (5/145) in group 1 and 1.3% (2/156) in group 2, whereas those in ESBL positive patients were 7.0% (4/57) in group 1 and 1.4% (1/72) in group 2. Conclusions: Increasing the dosage of amikacin for ciprofloxacin prophylaxis reduce infectious complications in patients with FQ-resistant rectal flora and to be more effective in ESBL positive patients with FQ-resistant rectal flora.

• 한국임상약학회지
• /
• 제31권1호
• /
• pp.35-43
• /
• 2021

Background: Migraine is a common neurological disorder that affects the quality of life and causes several health problems. Preventive migraine treatment can reduce migraine frequency, headache severity, and health care costs. This study aimed to estimate the utilization of migraine preventive therapy and associated factors in eligible patients. Methods: We studied 534 patients with migraine who were eligible for migraine preventive therapy using 2017 National Patient Sample (NPS) data from the Health Insurance Review and Assessment Service (HIRA). We estimated the migraine days by calculating the monthly average number of defined daily dose (DDD) of migraine-specific acute drug. Patients with a monthly average number of DDD of 4 or more were considered as subjects for preventive treatment. Chi-square test and multiple logistic regression analysis were used to determine the association between the preventive therapy and the influencing variables. Results: Less than half of the eligible patients for prophylaxis (n=234, 43.8%) were prescribed preventive therapy. Multiple logistic regression results show that migraine preventive therapy was influenced by age, the type of migraine, and some comorbidities. Patients over the age of 50 tend to receive less prophylactic treatment than under the age of 40. On the other hand, migraine patients with epilepsy or depression were more likely to receive preventive therapy. Sumatriptan was the most preferred medication for acute treatment, and propranolol was the most commonly prescribed drug for prevention. Conclusions: More than half of the patients who were candidates for migraine prophylaxis were not receiving suitable preventive treatment. Positive factors affecting the use of migraine prevention were the presence of comorbidities such as epilepsy and depression.

• Journal of Preventive Medicine and Public Health
• /
• 제57권1호
• /
• pp.8-17
• /
• 2024

Objectives: The effectiveness and efficiency of pre-exposure prophylaxis (PrEP) in reducing the transmission of human immunodeficiency virus (HIV) among men who have sex with men (MSM) relies on how widely it is adopted and adhered to, particularly among high-risk groups of MSM. The meta-analysis aimed to collect and analyze existing evidence on various factors related to PrEP adherence in MSM, including demographic characteristics, sexual behaviors, substance use, and psychosocial factors. Methods: The meta-analysis followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The search included articles published between January 2018 and December 2022, obtained from the PubMed, ScienceDirect, and Scopus databases. The studies that were included in the analysis reported the proportion of MSM who demonstrated adherence to PrEP and underwent quality appraisal using the Newcastle-Ottawa Scale. Results: Of the 268 studies initially identified, only 12 met the inclusion criteria and were included in the final meta-analysis. The findings indicated that education (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.12 to 2.40), number of sexual partners (OR, 1.16; 95% CI, 1.02 to 1.31), engaging in sexual activities with an human immunodeficiency virus-positive partner (OR, 1.59; 95% CI, 1.16 to 2.26), substance use (OR, 0.83; 95% CI, 0.70 to 0.99), and lower levels of depression (OR, 0.55; 95% CI, 0.37 to 0.82) were associated with higher rates of PrEP adherence among MSM. Conclusions: Despite these findings, further research is necessary to investigate PrEP adherence more comprehensively. The findings of this meta-analysis can be utilized to inform interventions aimed at improving PrEP adherence among MSM and provide directions for future research in this area.

• Clinical and Experimental Pediatrics
• /
• 제50권7호
• /
• pp.636-642
• /
• 2007

목 적 : 면역력이 약한 미숙아나 저체중 출생아에 여러 가지 침습적 조작으로 인한 항생제 사용이 진균 감염, 특히 칸디다 감염의 위험을 증가시킨다. 이를 감소시키기 위한 방법으로 fluconazole 예방요법이 칸디다 감염율과 사망률을 감소시켰다는 보고가 있다. 본 연구는 1,500 g 미만의 극소저체중 출생아들에 대한 예방적 항진균제 사용이 칸디다 감염의 발생을 감소시키는데 효과적인지 알아보고자 하였다. 방 법 : 전남대학병원 신생아중환자실에 입원한 1,500 g 미만의 극소저체중 출생아 중 기관내 삽관이나 제대 동정맥 또는 경피적 중심정맥 삽입술을 받은 환아로, 예방적으로 항진균제를 사용하지 않았던 2005년 1월 1일부터 2005년 7월 31일까지 7개월간의 환아를 'fluconazole 비사용군'으로, 사용하였던 2006년 1월 1일부터 2006년 7월 31일까지 7개월간의 환아를 'fluconazole 사용군'으로 하였다. 사용군 29명, 비사용군 28명을 대상으로 진균 감염의 위험인자로 알려진 임상특성과 칸디다 감염증의 발생빈도, 사망률 및 fluconazole의 약물 부작용을 관찰하였다. Fluconazole은 생후 첫 3일에 시작하여 4주간 예방적으로 투여하였으며 시행 첫 1주일은 체중(kg)당 3 mg을 3일 간격으로, 그 다음 주부터는 격일로 투여하였다. 결 과 : 두 군 사이에 재태주령, 출생체중, 성별, 쌍생아, 분만방식에 차이는 없었다. 산과적 인자인 장기 조기 양막파수, 융모양막염 및 산전 스테로이드 사용 빈도에 유의한 차이는 없었다. 신생아 칸디다 감염증의 위험인자로 알려진 1,000 g 미만 초극소저체중 출생아 빈도와 예방적 항생제 사용, 총정맥내 영양요법, 제대동정맥 삽입술 빈도와 유지기간, 지방유제 투여기간 및 기관내 삽관과 지속적 양압환기 사용기간에 두 군간 차이는 없었으나, 비사용군에 비해 사용군이 경피적 중심정맥 삽입술과 지방유제 사용빈도가 높았고 경피적 중심정맥관 유지기간이 길었다. Fluconazole 사용군과 비사용군 간에 진균감염의 빈도와 사망률에 유의한 차이는 없었다. 사용군에서 Malassezia 진균혈증이 5명 발생하였지만 칸디다 감염은 1명도 발생하지 않아 비사용군 5명(칸디다혈증 3명, 침습성 칸디다증 2명)에 비해 유의하게 감소하였다(P<0.05). 결 론 : 극소저체중 출생아에서 fluconazole의 예방적 투여가 칸디다 감염의 발생빈도를 유의하게 감소시키는 것으로 보아 비용-효과 면에서 항진균제의 예방적 투여가 고려될 수 있겠으나, Malassezia 진균혈증의 증가 원인에 대해서도 추가적인 연구가 필요할 것으로 사료된다.

• 한국치위생학회지
• /
• 제11권6호
• /
• pp.843-852
• /
• 2011

Objectives : The aims of the study were to examine perceived oral malodor and self-reported need for oral and dental care among patients receiving oral prophylaxis services and provide guidelines for developing educational programs(toothbrushing method and tongue cleaning) for oral hygiene and oral malodor prevention. Methods : The survey was administered to a sample of 462 receiving voluntary oral prophylaxis service in a dental laboratory at the J School of Public Health in Korea. The subjects were asked a range of questions related to the degrees of perceived oral malodor and concern for oral health status, as well as their demographic information and need for oral and dental treatment. Univariate analyses using Chi-square and T-test with a P-value of .05 were performed using SPSS Version 12.0 for Windows. Results : 1. Male participants reported "moderately concerned for bad breath and smell" and "I don't care bad breath and smell" 39.1% and 26.2% respectively, while more female participants were concerned for oral malodor. "moderately concerned for malodor" and" highly concerned for malodor" 41.1% and 28.5%(p<.05). a significant difference among age groups was found. 19% of young adults (less than or equal to 29 years of age) reported "highly concerned for bad breath and smell" while 36.4% of older adults (greater than or equal to 50 years of age) reported "highly concerned for bad breath and smell"(p<.05). 2. 12 non-smoking participants (3.7%) and 15 smoking participants (10.8%) reported that they have perceived bad breadth and smell (p<.05). 3. Smoking participants reported a higher degree of need for oral malodor treatment than that of non-smoking participants 88.5% and 82% respectively(p<.05). 4. The participants who did regular toothbrushing more than 3 times a day reported "no malodor", 77 % as compared to 66.7% of the participants who did regular toothbrushing 2 times a day. Toothbrushing 2 times a day reported either "moderate malodor" or "sever malodor"(p<.01). Participants with more frequent toothbrushing reported less oral and breath odor as compared participants with less frequent toothbrushing. Conclusions : The study suggested that there is a need to oral prophylaxis for prevention and toothbrushing and tongue cleaning method oral malodor care and oral health status.

• Clinical and Experimental Pediatrics
• /
• 제56권11호
• /
• pp.490-495
• /
• 2013

Purpose: The use of cyclosporine and mini-dose methotrexate (MTX) is a common strategy for graftversus- host disease (GVHD) prophylaxis in allogeneic transplants. We investigated whether patients who receive fewer than the planned MTX doses are at increased risk for GVHD. Methods: The study cohort included 103 patients who received allogeneic transplants at the Department of Pediatrics of The Catholic University of Korea College of Medicine, from January 2010 to December 2011. MTX was administered on days 1, 3, 6, and 11 after transplant at a dose of 5 $mg/m^2$ each. Within the cohort, 76 patients (74%) received all 4 doses of MTX [MTX(4) group], while 27 patients (26%) received 0-3 doses [MTX(0-3) group]. Results: Although there was no difference in neutrophil engraftment between the 2 groups, platelet engraftment was significantly faster in the MTX(4) group (median, 15 days), compared to the MTX(0- 3) group (median, 25 days; P =0.034). The incidence of grades II-IV acute GVHD was not different between the MTX(4) and MTX(0-3) groups (P =0.417). In the multivariate study, human leukocyte antigen mismatch was the most significant factor causing grades II-IV acute GVHD (P =0.002), followed by female donor to male recipient transplant (P =0.034). No difference was found between the MTX(4) and MTX (0-3) groups regarding grades III-IV acute GVHD, chronic GVHD, and disease-free survival. Conclusion: Our results indicate that deviations from the full dose schedule of MTX for GVHD prophylaxis do not lead to increased incidence of either acute or chronic GVHD.

• 한국치위생학회지
• /
• 제10권6호
• /
• pp.1083-1093
• /
• 2010

Objective : The purpose of this study was to examine the relationship of the oral health behavior of oral prophylaxis clients and some residents in a community to their simplified oral environment index. Methods : The subjects in this study were 520 people who had their teeth cleaned in the oral prophylaxis practice lab in the department of dental hygiene at J health college. A survey was conducted from March 23 to June 3, 2010, by way of the self-reported questionnaire. The data materials are analyzed by general characteristics frequency and ratio, the relationship of oral health behavior and sex, age, scaling experience, simplified oral hygiene index $x^{2}$ test analysis. Results : 1. Concerning links between gender and oral health behavior including daily toothbrushing frequency, the largest group of the respondents brushed their teeth three times a day(p<0.05). As to educational experiences on toothbrushing method and the use of oral hygiene supplies, the women had more educational experiences than the men(p<0.05). 2. Regarding connections between age and oral health behavior involving daily toothbrushing frequency, the largest number of the respondents brushed their teeth three times a day in every age group (p <0.001). As for educational experiences on toothbrushing method, those who were in their 50s and up(64.7%) learned about that, and they had more educational experiences with age(p<0.05). As for scaling experiences, the older respondents had their teeth scaled more often (p<0.001). 3. As to relationship between scaling experiences and oral health behavior, there were differences in toothbrushing frequency according to scaling experiences(p <0.05). Regarding educational experiences on toothbrushing method, those who had their teeth cleaned received more toothbrushing education(p<0.001). Concerning smoking, the nonsmokers had more experiences to get their teeth cleaned (p<0.001). 4. As for links between simplified oral environment index and oral health behavior including a time for toothbrushing, the respondents who did toothbrushing after every meal(80.4%) had good simplified oral environment indexes(p<0.05). 5. In regard to relationship between simplified oral environment index and oral health behavior, oral environment index had a positive correlation to the use of oral hygiene supplies( r=0.129**), toothbrushing time(r=0.116**) and educational experiences on toothbrushing method (r=0.099**). Smoking(r=-0.092**) had a negative correlation to that. Conclusion : The above-mentioned findings illustrate that oral health behavior is one of crucial factors to affect oral health status and oral environment care. Therefore oral prophylaxis practice lab visitors should receive education on the right toothbrushing method and the use of oral hygiene supplies to promote their oral health, and an incremental oral health care system that involves regular scaling should be introduced.