• Journal of the Korean Statistical Society
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• v.35 no.3
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• pp.239-250
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• 2006

A $2{\times}2$ crossover design including carryover effect is considered for assessment of population bioequivalence of two drug formulations in a Bayesian framework. In classical analysis, it is complex to deal with the carryover effect since the estimate of the drug effect is biased in the presence of a carryover effect. The proposed method in this article uses uninformative priors and vague proper priors for objectiveness of priors and the posterior probability distribution of the parameters of interest is derived with given priors. The posterior probabilities of the hypotheses for assessing population bioequivalence are evaluated based on a Markov chain Monte Carlo simulation method. An example with real data set is given for illustration.

• The Journal of the Korean dental association
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• v.47 no.3
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• pp.122-130
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• 2009

For the successful guided bone regeneration(GBR) of maxillary bony defect, proper soft tissue coverage is one of the most important things. Soft tissue dehiscence can be most common reason of osseous reconstruction failure. If a vascular supply to the graft should not develop from the host tissue, then the graft may also foil. Both of these prerequisites can be aided by judicious use of the buccal fat pad(BFP). Many methods for adequate soft tissue coverage have been proposed and the use of the BFP is one of them. BFP is useful in posterior maxillary area, can cover larger area and have higher blood flow than other methods. so the use of the BFP may offer protection and early blood supply to maxillary bone graft. This report describes the history, anatomy, blood flow, and clinical usefulness with two clinical cases.

• The Journal of the Korean dental association
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• v.53 no.7
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• pp.450-456
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• 2015

Even the adult cleft lip and palate patient who has not had timely treatment during the growth period, can be treated with orthodontic treatment without the necessity of orthognathic surgery if only the patient is treated under correct diagnosis and fitting appliances. Initially, maxillary arch form is established by constructing trifocal circles. Posterior region can be expanded and derotated laterally with pentahelix and anterior teeth are aligned with Tiggle brackets and "ㄷ"-shaped spring. Thereafter, anterior and posterior regions are consolidated. Mandibular intercanine width should be adjusted to maxillary intercanine width which was unavoidably reduced. Mandibular anterior tooth extraction will be helpful to attain proper mandibular intercanine width and better anterior dental showing.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.3
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• pp.198-203
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• 2023

Purpose. The aim of this study was to evaluate the proximal contact with a dental floss compared to a celluloid strip and a metal strip in normal dental arch and investigate what the most effective method for measuring is. Materials and methods. The subjects of this study was consisted with 20 healthy adults (10 males and 10 females) who had normal dentition. A dentist with more than 5 years of clinical experience evaluated the proximal contacts using a dental floss method, a celluloid strip method, and a metal strip method. Statistical analysis were performed by the use of Mann-Whitney U test. A P-value < .05 was considered statistically significant in all analysis. In addition, in the evaluation of proximal contact using a dental floss, the measurement of proximal contact using a celluloid strip and a metal strip was compared. Results. 80 % of all proximal contact was proper. Proper proximal contact was observed at the posterior area compared to the anterior area (P < .05). And male had proper proximal contact at the anterior area, female had proper proximal contact at the posterior area (P < .05). The consistency analysis between the results of the celluloid strip and the metal strip experiment on the results obtained from the floss using the consistency scale Kappa index shows that using celluloid strip is more advantageous than using the metal strip. Conclusion. Only 80% of all proximal contact was proper. Using celluloid strips with various thickness for evaluating of proximal contact is considered to be helpful for accurate measuring of proximal contact.

• Journal of KIISE:Computer Systems and Theory
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• v.31 no.10
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• pp.575-587
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• 2004

In this paper. a new Fast Expectation-Maximization algorithm(FEM) is proposed. Firstly the K-means algorithm is modified to reduce the number of iterations for finding the initial values that are used as the initial values in EM process. Conventionally the Initial values in K-means clustering are chosen randomly. which sometimes forces the process of clustering converge to some undesired center points. Uniform partitioning method is added to the conventional K-means to extract the proper initial points for each clusters. Secondly the effect of posterior probability is emphasized such that the application of Maximum Likelihood Posterior(MLP) yields fast convergence. The proposed FEM strengthens the characteristics of conventional EM by reinforcing the speed of convergence. The superiority of FEM is demonstrated in experimental results by presenting the improvement results of EM and accelerating the speed of convergence in parameter estimation procedures.

• The Journal of Korean Academy of Prosthodontics
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• v.58 no.2
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• pp.153-160
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• 2020

Gradual tooth wear is a natural process of aging, but pathological wear over physiologic ranges leads to functional and esthetic problems. The loss of posterior support may cause pathological wear of anterior teeth, which results in reduction of vertical dimension and disharmony of occlusal plane. To solve this problem, determination of proper vertical dimension considering centric relation is necessary. This case report presented 71-year-old male, who had the severe wear of lower anterior teeth due to loss of posterior support. By meticulous evaluation, a full mouth rehabilitation with elevation of vertical dimension was planned. After 8 months of follow-up, stable occlusal scheme is maintained and patient was satisfied with clinical outcome functionally and esthetically.

• Journal of Korean Neurosurgical Society
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• v.46 no.4
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• pp.328-332
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• 2009

Objective : The purpose of this study was to establish new fusion criteria to complement existing Brantigan-Steffee fusion criteria. The primary purpose of intervertebral cage placement is to create a proper biomechanical environment through successful fusion. The existence of a traction spur is an essential predictable radiologic factor which shows that there is instability of a fusion segment. We studied the relationship between the existence of a traction spur and fusion after a posterior lumbar interbody fusion (PLIF) procedure. Methods : This study was conducted using retrospective radiological findings from patients who underwent a PLIF procedure with the use of a cage without posterior fixation between 1993 and 1997 at a single institution. We enrolled 183 patients who were followed for a minimum of five years after the procedure, and used the Brantigan-Steffee classification to confirm the fusion. These criteria include a denser and more mature bone fusion area than originally achieved during surgery, no interspace between the cage and the vertebral body, and mature bony trabeculae bridging the fusion area. We also confirmed the existence of traction spurs on fusion segments and non-fusion segments. Results : The PLIF procedure was done on a total of 251 segments in 183 patients (71 men and 112 women). The average follow-up period was $80.4{\pm}12.7$ months. The mean age at the time of surgery was $48.3{\pm}11.3$ years (range, 25 to 84 years). Among the 251 segments, 213 segments (84.9%) were fused after five years. The remaining 38 segments (15.1%) were not fused. An analysis of the 38 segments that were not fused found traction spur formation in 20 of those segments (52.6%). No segments had traction spur formation with fusion. Conclusion : A new parameter should be added to the fusion criteria. These criteria should be referred to as 'no traction spur formation' and should be used to confirm fusion after a PLIF procedure.

• Archives of Reconstructive Microsurgery
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• v.25 no.2
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• pp.37-42
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• 2016

Purpose: Soft tissue coverage of the distal leg and ankle region represents a surgical challenge. Beside various local and free flaps, the perforator flap has recently been replaced as a reconstructive choice because of its functional and aesthetic superiority. Although posterior tibial artery perforator flap (PTAPF) has been reported less often than peroneal artery perforator flap, it also provides a reliable surgical option in small to moderate sized defects especially around the medial malleolar region. Materials and Methods: Seven consecutive patients with soft tissue defect in the ankle and foot region were enrolled. After Doppler tracing along the posterior tibial artery, the PTAPF was elevated from the adjacent tissue. The average size of the flap was $28.08{\pm}9.31cm^2$ (range, 14.25 to $37.84cm^2$). The elevated flap was acutely rotated or advanced. Results: Six flaps survived completely but one flap showed partial necrosis because of overprediction of the perforasome. No donor site complications were observed during the follow-up period and all seven patients were satisfied with the final results. Conclusion: For a small to medium-sized defect in the lower leg, we conducted the close-by islanded PTAPF using a single proper adjacent perforator. Considering the weak point of the conventional propeller flap, this technique yields much better aesthetic results as a simple and reliable technique especially for defects of the medial malleolar region.

• Journal of Korean Neurosurgical Society
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• v.30 no.8
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• pp.981-984
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• 2001

Object : To treat hydrocephalus by ventriculo-peritoneal shunt operation, the correct positioning of the proximal catheter in the ventricle is very important. The purpose of this study was to develop the "shunt guiding kit" for the proper positioning of the proximal shunt catheter to the ventricle in the ventriculo-peritoneal shunt operation. Materials and Methods: The "shunt guiding kit" is made of tungsten alloy and it consists of one frame, two screws and one guider. Through the guider, the proximal shunt catheter operates by mechanically coupling the posterior burr hole to the anterior target point. Results: We have treated three hydrocephalus patients with use of the "shunt guiding kit", and achieved good location of proximal shunt catheters. Conclusion: We developed the "shunt guiding kit" for the proper positioning of the proximal shunt catheter to the ventricle, and this would be very useful for preventing ventriculo-peritoneal shunt malfunction and preventing possible brain injury during the procedures.

• Journal of Korean Dental Science
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• v.3 no.2
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• pp.4-11
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• 2010

Purpose: This study aimed at examining the thickness of lateral cortical bone in the mandibular posterior body and the location of the inferior alveolar nerve canal as well as investigating the clinically viable bone grafting site(s) and proper thickness of the bone grafts. Subjects and Methods: The study enrolled a total of 49 patients who visited the Department of Oral and Maxillofacial Surgery at Kyung Hee University Dental Hospital to have their lower third molar extracted and received cone beam computed tomography (CBCT) examinations. Their CBCT data were used for the study. The thickness of lateral cortical bone and the location of inferior alveolar nerve canal were each measured from the buccal midpoint of the patients' lower first molar to the mandibular ramus area in the occlusal plane of the molar area. Results: Except in the external oblique ridge and alveolar ridge, all measured areas exhibited the greatest cortical bone thickness near the lower second molar area and the smallest cortical bone thickness in the retromolar area. The inferior alveolar nerve canal was found to be located in the innermost site near the lower second molar area compared to other areas. In addition, the greatest thickness of the trabecular bone was found between the inferior alveolar nerve canal and the lateral cortical bone. Conclusions: In actual clinical settings involving bone harvesting in the posterior mandibular body, clinicians are advised to avoid locating the osteotomy line in the retromolar area to help protect the inferior alveolar nerve canal from damage. Harvesting the bone near the lower second molar area is judged to be the proper way of securing cortical bone with the greatest thickness.