• Molecular & Cellular Toxicology
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• v.1 no.1
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• pp.1-6
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• 2005

Toxicology is a multidisciplinary field, and an important science that impacts both environmental health regulation and the development and practice of medicine. The rapid progress in cellular and molecular biology, like many other branches of biomedical research, toxicology is now experiencing a renaissance fueled by the application of "omic" technologies to gain a better understanding of the biological basis of toxicology of drugs and other environmental factors. In this review on current progress on toxicology, the future perspective, concept, approaches and applications of toxicogenomics as next generation promising technology in toxicology field will be described.

• Natural Product Sciences
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• v.28 no.3
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• pp.93-104
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• 2022

Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to the global healthcare system. Ineffective and resistance to antibiotic treatments have increased morbidity and mortality rates worldwide. New and effective antibiotics are needed to combat against bacterial resistance. Endophytic fungi are crucial reservoirs of novel bioactive metabolites. In particular, the secondary metabolites show promising therapeutic potential, notably, antibacterial. This review discussed the emerging potential of endophytic fungi as anti-MRSA agents. The ecological sources of endophytic fungi were discussed with the synthesis of bioactive metabolites. The mode of antibacterial actions was elucidated to give a better understanding of the mechanisms involved. This review may serve as an important reference for future discovery and developments of anti-MRSA agents from endophytic fungi.

• Journal of Integrative Natural Science
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• v.15 no.4
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• pp.153-161
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• 2022

c-Jun N-terminal kinases (JNKs) are members of MAPK family. Many genes can relay signals that promote inflammation, cell proliferation, or cell death which causes several diseases have been associated to mutations in the JNK gene family. The JNK2 gene is significantly more important in cancer development than the JNK1 and JNK3 genes. There are several different ways in which JNK2 contributes to breast cancer, and one of these is through its role in cell migration. As a result, this study's primary objective was to employ computational strategies to identify promising leads that potentially target the JNK2 protein in a strategy to alleviate breast cancer. We have derived these anticancer compounds from marine brown seaweed called Turbinaria conoides. We have identified compounds Ethane, 1, 1-diethoxy- and Butane, 2-ethoxy as promising anti-cancer drugs by molecular docking, DFT, and ADME study.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.11a
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• pp.48-51
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• 2011

Universal Plug and Play (UPnP) is one of the most promising home network middleware technologies because of its straightforward implementation and zero configuration characteristics. However, it has a limitation of the operations only IP based network and proceeding in a single IP subnet. In this paper, we proposed network bridge architecture for UPnP network to interoperate heterogeneous network, UPnP and ZigBee. The proposed network bridge architecture is capable of configuration ZigBee device as a virtual UPnP device. This technique is promising for seamless inter-networking with ZigBee and UPnP network. Also, the architecture of the proposed network bridge architecture can be applied for a future smart home.

• The Journal of the Korea Contents Association
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• v.19 no.5
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• pp.104-114
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• 2019

In the global market competition, countries and businesses are actively engaged in technology prediction activities to maximize their profits by attempting to enter and preempting the core technology of the future. In this paper, we propose a growth model based on patent application trends to predict the time to replace a product with a promising new technology to dominate the market. Although the Fisher-Pry model that Bhargava generalized to predict the emergence of promising alternative technologies was relatively satisfactory compared to the original Fisher-Pry model, it was difficult to predict the replacement rate behavior properly due to a parameter problem. The application of the Fisher-Pry Modification Model in the form of a quadratic equation through the patent trend analysis of the optical storage system for the purpose of verifying the time alternative to the light storage technology has resulted in satisfactory verification results. It is expected that small and medium-sized companies and individual researchers will apply this model and use it more easily to predict the time to replace the market for promising replacement technologies.

• Journal of Technology Innovation
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• v.21 no.2
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• pp.25-56
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• 2013

As science and technology are emphasized as national competitiveness, major nations designate new growth engine industry and establish the effective investment and the development strategy to enhance industrial development and competitiveness through science and technology. New industrial sectors such as Biotechnology and renewable energy have been spot lighted as major new growth engines and this competitive situation is getting fiercer. Universities and research institutions in each country selected and announced the future promising technological field which will produce ripple effect in the future on a regular basis. In Korea, various research institutions continue to select and announce the promising technological fields. In this study, we would like to study the method to derive the promising technological field in the field of biotechnology spotlighted as a new growth engine by utilizing patent information. We would like to derive the major technological field by collecting domestic and international patents in the field of biotechnology using IPC code based technological classification and identifying bio technological trends utilizing text mining method for analysis of technological development trends with patents. Patent contour of US and Korea is compared and analyzed through analysis of text mining to derive the general technological development field in the field of biotechnology. After that, we would like to investigate research theme of promising biotechnology focused technological development through details on technological trends through in-depth analysis about technological field which draws interest more and more in Korea and other countries.

• Proceedings of the Korea Contents Association Conference
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• 2014.06a
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• pp.267-268
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• 2014

• Proceedings of the Korea Technology Innovation Society Conference
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• 2006.11b
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• pp.255-272
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• 2006

• Proceedings of the Korea Technology Innovation Society Conference
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• 2005.05a
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• pp.249-262
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• 2005

• Journal of the Semiconductor & Display Technology
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• v.14 no.3
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• pp.13-22
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• 2015

LED (Light Emitting Diode) lighting is gaining more and more market penetration as one of the global warming countermeasures. LED is the next generation of fusion source composed of epi/chip/packaging of semiconductor process technology and optical/information/communication technology. LED has been applied to the existing industry areas, for example, automobiles, TVs, smartphones, laptops, refrigerators and street lamps. Therefore, LED makers have been striving to achieve the leading position in the global competition through development of core source technologies even before the promotion and adoption of LED technology as the next generation growth engine with eco-friendly characteristics. However, there has been a point of view on the cost compared to conventional lighting as a large obstacle to market penetration of LED. Therefore, companies are developing a Chip-Scale Packaging (CSP) LED technology to improve performance and reduce manufacturing costs. In this study, we perform patent analysis associated with Flip-Chip CSP LED and flow chart for promising technology forecasting. Based on our analysis, we select key patents and key patent players to derive the business strategy for the business success of Flip-Chip CSP PKG LED products.