• Title/Summary/Keyword: Prognosis

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FACTORS AFFECTING 6 MONTHS' SHORT-TERM PROGNOSIS OF CONDUCT DISORDER IN THE ADOLESCENTS (청소년 행동장애의 6개월 단기 예후에 영향을 미치는 변인)

  • Chin, Tae-Won;Chae, Jeong-Ho;Choi, Choong-Sik
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.7 no.2
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    • pp.153-160
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    • 1996
  • The purpose of this study is to find out the factors that affect the prognosis of conduct disorder in the adolescents. According to the nature or behavioral problems during 6 months after discharge, the good prognosis group(N=37) and the poor prognosis group(N= 36) were selected and scores of Youth Self Report(YSR), MMPI, KWIS were compared between both groups. The following results were obtained. 1) In family environmental factors, no significant difference was found between both groups. 2) In YSL total problem score, score of externalizing syndrome and score of delinquent behavior were significantly higher in the poor prognosis group. 3) In MMPI, no significant difference was found between both groups. 4) In KWIS, total 1.0. did not show significant differences between both groups. Our hypothesis that the prognosis of conduct disorder in adolescent is poorer in cases with higher quantities of problematic behaviors is certified.

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Proposal on the Process and Prognosis of Popular Diseases (질병의 경과와 예후 판별에 대한 제언)

  • Kwon, Ki-Rok
    • Journal of Pharmacopuncture
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    • v.11 no.1
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    • pp.201-209
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    • 2008
  • Objectives : This study was designed to make beneficial proposal for clinical application on some of the most common disorders treated by Oriental medicine by analyzing treatment process and prognosis. Methods : Number of peculiar attributes pertaining to a specific disorder were analyzed and based on those attributes, patterns associated with process and prognosis were interpreted in reference with classical literatures. Results : 1. Factors which can influence the progression and prognosis include time of onset, intensity of symptoms, course of passage, effects of risk factors, condition of the patient's righteous qi(正氣), accuracy of differential diagnosis made by the practitioner, accuracy of treatment methods, and other unexpected external influences. 2. Correlation between the condition of disorders and treatment progression is closely associated with proper treatment procedures and performances. The time of onset and intensity play critical roles in the treatment process and prognosis and showed pattern tendency with mutual interactions. 3. When there is complication of various disorders, it is ideal to give priority to more urgent illness and take care of moderate illness later. If there isn't any correlation between disorders, treat them in the order of acute to chronic disorders. The approach is reversed when disorders are related, treating in the order of most chronic to most acute. 4. In a case of complication of various disorders, depending on the disorder being acute or chronic, intensity, and accuracy of treatments, either a domino effect or gradual fade out of symptoms were witnessed. 5. The concept of "Five Evils Theory" according to Nan Jing(Difficult Classic) is essential in grasping disease progression due to interrelationships between zangfu organs. Conclusions : Predicting of disease process and prognosis for vast array of disorders treated by Oriental medicine is a very difficult task, yet evaluating the disorder's peculiar properties and influential factors resulted in few principles which can be effectively applied into clinical applications.

The Clinical observation of acute Bell's palsy 80 Case (급성기 안면마비 (Bell's palsy) 환자의 예후 및 치료율에 대한 임상고찰 80례)

  • Won, Jae-Sun;Chou, Ching-Yu;Cho, Ah-Reum;Kim, Ji-Hyun;Kim, Chang-Hwan
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.23 no.2
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    • pp.151-162
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    • 2010
  • Objective : Bell's palsy is common and has many clinic study. but bell's palsy prognosis is not enough specific. So this study was evaluated bell's palsy prognosis, treatment number, sequela of normal group and bad prognosis group. Methods : From June 2009 to June 2010, patients who visited Dong-seo Oriental Medicine ENT. A clinic study was done on patient who were diagnosed bell's palsy, onset 2weeks within when first visited OPD and treated 3 times over in Dong-seo Oriental Medicine Cental. To evaluate grade of paralysis, House-Brackman Scale was used. We classified treatment numbers of each HB-Scale group, normal gIVroup and bad prognosis group. Results : The distribution of Onset HB-Scale : Gr II 26.25%, Gr III 67.5%, Gr IV 6.25% Onset HB-Scale Gr II patients completely recover 100% Onset HB-Scale Gr III patients completely recover 64.8%, improved 27.8%, nothing change 7.4% Onset HB-Scale Gr IV patients completely recover 40%, improved 60% Onset HB-Scale Gr II & IV patients recovery percentage make no difference of normal group (Group A) and bad prognosis. Onset HB-Scale Gr III patients completely recover Group A 66.7%, Group B 52.9%, improved Group A 23.2%, Group 35.3%, noting change Group A 5.1%, Group B 11.8% Onset HB-Scale Gr II patients has no sequela. Onset HB-Scale Gr III & IV patients has tendency that they treat more times, more improving and less sequela probability Conclusion : Onset HB-Scale is the indicator of acute bell's palsy prognosis.

Involvement of MicroRNA-198 Overexpression in the Poor Prognosis of Esophageal Cancer

  • Qi, Bo;Yao, Wen-Jian;Zhao, Bao-Sheng;Qin, Xiu-Guang;Wang, Yi;Wang, Wen-Ju;Wang, Tian-Yun;Liu, Shang-Guo;Li, Han-Chen
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.5073-5076
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    • 2013
  • Objective: This study aimed to investigate whether the miR-198 expression level is related to clinicopathological factors and prognosis of esophageal cancer. Methods: MicroRNA was extracted from esophageal cancer patients who underwent surgery for assessment using the Taqman@ MicroRNA assay. The correlation between miR-198 expression and clinicopathological features was analyzed, and the significance of miR-198 as a prognostic factor and its relationship with survival was determined. Results: MicroRNA-198 (miR-198) expression was higher in patients with poor prognosis than those with good prognosis (P<0.05). Kaplan-Meier analysis results showed that the miR-198 expression level had a significant correlation with survival time (P=0.030) and that patients with a higher expression of miR-198 had a shorter survival time. Cox multi-factor model analysis showed that patient prognosis (P=0.014), tumor length (P=0.040) and expression (P=0.012), and survival time had a significant correlation; the corresponding risks were 7.268, 1.246, and 3.524, respectively. Conclusion: miR-198 overexpression is involved in the poor prognosis of esophageal cancer and can be used as a biomarker for selection of cases requiring especial attention.

Path Analysis for Delirium on Patient Prognosis in Intensive Care Units (섬망이 중환자실 환자결과에 미치는 영향: 경로 분석)

  • Lee, Sunhee;Lee, Sun-Mi
    • Journal of Korean Academy of Nursing
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    • v.49 no.6
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    • pp.724-735
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    • 2019
  • Purpose: This study was conducted to investigate relationship between delirium, risk factors on delirium, and patient prognosis based on Donabedian's structure-process-outcome model. Methods: This study utilized a path analysis design. We extracted data from the electronic medical records containing delirium screening data. Each five hundred data in a delirium and a non-delirium group were randomly selected from electronic medical records of medical and surgical intensive care patients. Data were analyzed using SPSS 20 and AMOS 24. Results: In the final model, admission via emergency department (Β=.06, p=.019), age over 65 years (Β=.11, p=.001), unconsciousness (Β=.18, p=.001), dependent activities (Β=.12, p=.001), abnormal vital signs (Β=.12, p=.001), pressure ulcer risk (Β=.12, p=.001), enteral nutrition (Β=.12, p=.001), and use of restraint (Β=.30, p=.001) directly affecting delirium accounted for 56.0% of delirium cases. Delirium had a direct effect on hospital mortality (Β=.06, p=.038), hospital length of stay (Β=5.06, p=.010), and discharge to another facility (not home) (Β=.12, p=.001), also risk factors on delirium indirectly affected patient prognosis through delirium. Conclusion: The use of interventions to reduce delirium may improve patient prognosis. To improve the dependency activities and risk of pressure ulcers that directly affect delirium, early ambulation is encouraged, and treatment and nursing interventions to remove the ventilator and drainage tube quickly must be provided to minimize the application of restraint. Further, delirium can be prevented and patient prognosis improved through continuous intervention to stimulate cognitive awareness and monitoring of the onset of delirium. This study also discussed the effects of delirium intervention on the prognosis of patients with delirium and future research in this area.

A Study on the Three Yin Diseases(三陰病) in the 『Shanghanlun(傷寒論)』 -Focusing on Prognosis Analysis- (『상한론(傷寒論)』 삼음병(三陰病)에 대한 연구(硏究) - 예후 분석을 중심으로 -)

  • Park, Sang-Kyun;BANG, Jung-Kyun
    • Journal of Korean Medical classics
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    • v.34 no.1
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    • pp.47-65
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    • 2021
  • Objectives : An accurate judgment of prognosis when treating diseases is crucial. While the 『Shanghanlun(傷寒論)』 deals with the prognosis of the Three Yin Diseases with great importance, full-scale studies have been lacking. This paper aims to study the Three Yin Diseases with a focus on prognosis analysis. Methods : Among the Three Yin Disease verses, those that could provide clues to prognosis were selected and analysed. Conclusions & Results : When Yang pulse patterns such as long(長脈)·floating(浮脈)·rapid(數脈) pulses and Yang symptoms such as fever, vexing heat, mild perspiration, thirst, warmth in hands and feet are present in Yin disease, it could be taken as signs of Yang Qi restoration. In these situations, Yin Cold pattern such as diarrhea and reversal cold disappear and the prognosis is positive. However, despite Yang pulse patterns and symptoms, there are cases where diarrhea happens as a result of cold dampness being eliminated due to Yang Qi restoration. Also, when Yang Qi starts communicating smoothly after its restoration in the Three Yin Diseases, perspiration can happen. When diarrhea and reversal cold, which are patterns of Yin Cold get worse, with pulse patterns such as unfelt(脈不至)·replete(實脈)·fulminating(脈暴出) pulses, false heat symptoms such as fever and hot flashes happen, accompanied with Yang Qi depleted symptoms such as inability to lie down due to agitation, continuous perspiration, sore throat, dyspnea, and exaggerated breathing happen. When fast pulse, fever, and perspiration are present due to depression and stagnation of ministerial fire, symptoms such as bloody stool with pus, purulent abscess, sore throat, and inability to lie down due to agitation show, which signal negative prognosis. In bad cases of Reverting Yin Disease, there is continuous diarrhea and bloody stool with pus, which can be due to either Kidney Yang deficiency or depression and stagnation of ministerial fire. It could also be caused by excessive heat.

Data-driven approach to machine condition prognosis using least square regression trees

  • Tran, Van Tung;Yang, Bo-Suk;Oh, Myung-Suck
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.11a
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    • pp.886-890
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    • 2007
  • Machine fault prognosis techniques have been considered profoundly in the recent time due to their profit for reducing unexpected faults or unscheduled maintenance. With those techniques, the working conditions of components, the trending of fault propagation, and the time-to-failure are forecasted precisely before they reach the failure thresholds. In this work, we propose an approach of Least Square Regression Tree (LSRT), which is an extension of the Classification and Regression Tree (CART), in association with one-step-ahead prediction of time-series forecasting technique to predict the future conditions of machines. In this technique, the number of available observations is firstly determined by using Cao's method and LSRT is employed as prognosis system in the next step. The proposed approach is evaluated by real data of low methane compressor. Furthermore, the comparison between the predicted results of CART and LSRT are carried out to prove the accuracy. The predicted results show that LSRT offers a potential for machine condition prognosis.

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Impact of Regional Emergency Medical Access on Patients' Prognosis and Emergency Medical Expenditure (지역별 응급의료 접근성이 환자의 예후 및 응급의료비 지출에 미치는 영향)

  • Kim, Yeonjin;Lee, Tae-Jin
    • Health Policy and Management
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    • v.30 no.3
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    • pp.399-408
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    • 2020
  • Background: The purpose of this study was to examine the impact of the regional characteristics on the accessibility of emergency care and the impact of emergency medical accessibility on the patients' prognosis and the emergency medical expenditure. Methods: This study used the 13th beta version 1.6 annual data of Korea Health Panel and the statistics from the Korean Statistical Information Service. The sample included 8,119 patients who visited the emergency centers between year 2013 and 2017. The arrival time, which indicated medical access, was used as dependent variable for multi-level analysis. For ordinal logistic regression and multiple regression, the arrival time was used as independent variable while patients' prognosis and emergency medical expenditure were used as dependent variables. Results: The results for the multi-level analysis in both the individual and regional variables showed that as the number of emergency medical institutions per 100 km2 area increased, the time required to reach emergency centers significantly decreased. Ordinal logistic regression and multiple regression results showed that as the arrival time increased, the patients' prognosis significantly worsened and the emergency medical expenses significantly increased. Conclusion: In conclusion, the access to emergency care was affected by regional characteristics and affected patient outcomes and emergency medical expenditure.

Modeling of Breast Cancer Prognostic Factors Using a Parametric Log-Logistic Model in Fars Province, Southern Iran

  • Zare, Najaf;Doostfatemeh, Marzieh;Rezaianzadeh, Abass
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1533-1537
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    • 2012
  • In general, breast cancer is the most common malignancy among women in developed as well as some developing countries, often being the second leading cause of cancer mortality after lung cancer. Using a parametric log-logistic model to consider the effects of prognostic factors, the present study focused on the 5-year survival of women with the diagnosis of breast cancer in Southern Iran. A total of 1,148 women who were diagnosed with primary invasive breast cancer from January 2001 to January 2005 were included and divided into three prognosis groups: poor, medium, and good. The survival times as well as the hazard rates of the three different groups were compared. The log-logistic model was employed as the best parametric model which could explain survival times. The hazard rates of the poor and the medium prognosis groups were respectively 13 and 3 times greater than in the good prognosis group. Also, the difference between the overall survival rates of the poor and the medium prognosis groups was highly significant in comparison to the good prognosis group. Use of the parametric log-logistic model - also a proportional odds model - allowed assessment of the natural process of the disease based on hazard and identification of trends.

Clinicopathological Factors and Gastric Cancer Prognosis in the Iranian Population: a Meta-analysis

  • Somi, Mohammad Hossein;Ghojazadeh, Morteza;Bagheri, Masood;Tahamtani, Taraneh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.853-857
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    • 2015
  • Background: Gastric cancer is the most common cancer in the Iranian population. The aim of this study was to determine the effect of clinicopathological factors on prognosis by meta-analysis. Materials and Methods: A literature search was conducted using MEDLINE, EMBASE and Cochrane library and extensive literature search using the Persian databases until February 2011. Prospective follow up studies with multivariate analysis of overall survival of the patients with gastric cancer were included in this review. The data were analyzed by CMA.2. Publication bias are checked by funnel plot and data are shown as Forest plots. Results: From a total of 63 articles, 14 retrospective studies which examined 5 prognostic factors and involving 10,500 patients were included. Tumor size (>35mm) was the main significant factor predicting an unfavorable prognosis for the patients with gastric cancer (RR=1.829, p<0.001) followed by presence of distant metastases (RR=1.607, p<0.001), poor differentiation (RR=1.408, p<0.001) and male sex (RR=1.194, p<0.001). Lymph node metastases (RR=1.058, p=0.698) and moderate differentiation (RR=0.836, p=0.043) were not statistically significant as prognostic factors. Conclusions: This meta-analysis suggests that tumor size>35mm, poor differentiation, presence of distant metastasis and male gender are strongly associated with a poor prognosis in Iranian patients with gastric cancer.