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Reduction of Exposure Dose of Mammography by Comparison of Compression Paddle Material (압박대 재질 비교를 통한 유방촬영의 피폭선량 감소 방안)

  • Hong, Dong-Hee
    • Journal of radiological science and technology
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    • v.42 no.6
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    • pp.455-460
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    • 2019
  • This study compared the radiation transmission and image quality of polymethylmethacrylate (PMMA), polycarbonate (PC), and carbon, which are common components of the compression plates currently used during breast imaging. In addition to measuring the transmitted dose and the intensity without the use of a compression paddle, the four different compression paddles were evaluated according to the material and thickness of each paddle. Radiation transmittance, maximum intensity, and plot profile type w ere all evaluated for each material, and for each factor evaluated the follow ing order w as noted, from best to w orst: carbon 4 mm, PMMA 3 mm, PMMA 4 mm, and PC 4 mm. It is necessary to study a variety of materials and thicknesses in order to find the optimal combination of material and thickness, because not only does the material have a large influence in reducing the radiation exposure during mammography, but the thickness of the compression plate also has a great influence.

Kinetic Studies on the Nucleophilic Addition of Thiophenol Derivatives to 4'-[N- (9-Acridinyl) ]-1'-( N- methanesulfonyl) -3'-methoxyquinonediimide

  • 김태린;정동인;변상용
    • Bulletin of the Korean Chemical Society
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    • v.18 no.4
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    • pp.374-379
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    • 1997
  • The rate constants for the nucleophilic addition of thiophenol derivatives (p-OCH3, H, p-CH3, m-CH3, p-Br and p-NO2) to 4'-[N-(9-acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide (AMQD) were determined by ultraviolet spectrophotometer in water at 5 ℃, and rate equations which can be applied over a wide pH range were obtained. On the basis of pH-rate profile, Bronsted plot, adduct analysis, general base catalysis and substituent effect, a plausible mechanism of this addition reaction was proposed: Below pH 2.5, the reaction proceeded by the addition of thiophenol molecule to 6'-position of quinonoid after protonation at the acridinyl nitrogen. Above pH 6.2, the addition of sulfide anion to 6'-position of quinonoid was rate controlling. However, in the range of pH 3.0-6.0, these two reactions occured competively.

Comparison of Normalization Methods for Defining Copy Number Variation Using Whole-genome SNP Genotyping Data

  • Kim, Ji-Hong;Yim, Seon-Hee;Jeong, Yong-Bok;Jung, Seong-Hyun;Xu, Hai-Dong;Shin, Seung-Hun;Chung, Yeun-Jun
    • Genomics & Informatics
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    • v.6 no.4
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    • pp.231-234
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    • 2008
  • Precise and reliable identification of CNV is still important to fully understand the effect of CNV on genetic diversity and background of complex diseases. SNP marker has been used frequently to detect CNVs, but the analysis of SNP chip data for identifying CNV has not been well established. We compared various normalization methods for CNV analysis and suggest optimal normalization procedure for reliable CNV call. Four normal Koreans and NA10851 HapMap male samples were genotyped using Affymetrix Genome-Wide Human SNP array 5.0. We evaluated the effect of median and quantile normalization to find the optimal normalization for CNV detection based on SNP array data. We also explored the effect of Robust Multichip Average (RMA) background correction for each normalization process. In total, the following 4 combinations of normalization were tried: 1) Median normalization without RMA background correction, 2) Quantile normalization without RMA background correction, 3) Median normalization with RMA background correction, and 4) Quantile normalization with RMA background correction. CNV was called using SW-ARRAY algorithm. We applied 4 different combinations of normalization and compared the effect using intensity ratio profile, box plot, and MA plot. When we applied median and quantile normalizations without RMA background correction, both methods showed similar normalization effect and the final CNV calls were also similar in terms of number and size. In both median and quantile normalizations, RMA backgroundcorrection resulted in widening the range of intensity ratio distribution, which may suggest that RMA background correction may help to detect more CNVs compared to no correction.

Kinetic Studies on the Mechanism of Hydrolysis of 4'-[N-(9-Acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide (4'-[N-(9-Acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide의 가수분해 반응메카니즘에 관한 반응속도론적 연구)

  • Kim, Tae Rin;Chung, Dong In;Pyun, Sang Yong
    • Journal of the Korean Chemical Society
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    • v.40 no.12
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    • pp.733-740
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    • 1996
  • The rate constants for the hydrolysis of 4'-[N-(9-acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide(AMQD) were determined by ultraviolet visible spectrophotometer in water at $25^{\circ}C.$ The rate equation which could be applied over wide pH ranges were obtained. On the basis of pH-rate profile, Bronsted plot, hydrolysis product analysis, general base catalysis and substituent effect, the plausible hydrolysis mechanism was proposed: Below pH 3.00, the hydrolysis reaction was proceeded by the attack of water to 4'-position of quinonoid after protonation at nitrogen of acridinyl and between pH 3.00 and 9.00, the addition of water and hydroxide occurred competitively. However, above pH 9.00, the rate constants were dependent upon only the concentration of hydroxide ion.

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Change of NDVI by Surface Reflectance Based on KOMPSAT-3/3A Images at a Zone Around the Fukushima Daiichi Nuclear Power Plant (후쿠시마 제1 원전 주변 지역의 KOMPSAT-3/3A 영상 기반 지표반사도 적용 식생지수 변화)

  • Lee, Jihyun;Lee, Juseon;Kim, Kwangseob;Lee, Kiwon
    • Korean Journal of Remote Sensing
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    • v.37 no.6_3
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    • pp.2027-2034
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    • 2021
  • Using multi-temporal KOMPSAT-3/3A high-resolution satellite images, the Normalized Difference Vegetation Index (NDVI) for the area around the Fukushima daiichi nuclear power plant was determined, and the pattern of vegetation changes was analyzed. To calculate the NDVI, surface reflectance from the KOMPSAT-3/3A satellite image was used. Satellite images from four years were used, and the zones where the images overlap was designated as the area of interest (AOI) for the study, and by setting a profile passing through highly vegetated area as a data analysis method, the changes by year were examined. In addition, random points were extracted within the AOI and displayed as a box plot to quantitatively indicate change of NDVI distribution pattern. The main results of this study showed that the NDVI in 2014 was low within AOI in the vicinity of the nuclear power plant, but vegetated area continued to expand until 2021. These results were also confirmed in the change monitoring results shown in a profile or box plot. In disaster areas where access is restricted, such as the Fukushima nuclear power plant area, where it is difficult to collect field data, obtaining land cover classification products with high accuracy using satellite images is challenging, so it is appropriate to analyze them using primary outputs such as vegetation indices obtained from high-resolution satellite imagery. It is necessary to establish an international cooperation system for jointly utilizing satellite images. Meanwhile, to periodically monitor environmental changes in neighboring countries that may affect the Korean peninsula, it is necessary to establish utilization models and systems using high-resolution satellite images.

Three-Dimensional Subsurface Resistivity Profile using Electrical Resistance Tomography for Designing Grounding Grid (접지 그리드 설계를 위한 전기 저항 단층촬영법에 기반한 지표의 3차원 저항률 분포 추정)

  • Khambampati, Anil Kumar;Kim, Kyung Youn
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.4
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    • pp.117-128
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    • 2016
  • Installation of earth grounding system is essential to ensure personnel safety and correct operation of electrical equipment. Earth parameters, especially, soil resistivity has to be determined in designing an efficient earth grounding system. The most common applied technique to measure soil resistance is Wenner four-point method. Implementation of this method is expensive, time consuming and cumbersome as large set of measurements with variable electrode spacing are required to obtain a one dimensional resistivity plot. It is advantageous to have a method which is of low cost and provides fast measurements. In this perspective, electrical resistance tomography (ERT) is applied to estimate subsurface resistivity profile. Electrical resistance tomograms characterize the soil resistivity distribution based on the measurements from electrodes placed in the region of interest. The nonlinear ill-posed inverse problem is solved using iterated Gauss-Newton method with Tikhonov regularization. Through extensive numerical simulations, it is found that ERT offers promising performance in estimating the three-dimensional soil resistivity distribution.

Study of the Optimization and the Depth Profile Using a Flat Type Ion Source in Glow Discharge Mass Spectrometry

  • Woo Jin Chun;Kim, Hyo Jin;Lim Heoung Bin;Moon Dae Won;Lee Kwang Woo
    • Bulletin of the Korean Chemical Society
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    • v.13 no.6
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    • pp.620-624
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    • 1992
  • The analytical performance of glow discharge mass spectrometer (GD-MS), using a flat type ion source is discussed. The efficiency of ion extraction was maximized at the distance between anode and cathode of 6 mm. At the operation condition of 4 mA, -1000 volt, and 1 mbar for the source, the optimum voltages for sampler and skimmer were40 volt and -280 volt, respectively. The intensities of Cu, Zn, and Mn were increased as a function of square root of current approximately. Korea standard reference materials (KSRM) were tested for an application study. The detection limits of most elements were obtained in the range of several ppm at the optimized operating condition. The peaks of aluminum and chromium were interfered by those of residual gases. The depth profile of nickel coated copper specimens (3, 5, 10 ${\mu}m$ thickness) were obtained by plotting time versus intensities of Ni and Cr after checking the thickness of nickel coated using a scanning electron microscope (SEM). At this moment, the sputtering rate of 0.2 ${\mu}m/min$ at the optimum operating condition was determined from the slope of the plot of time to the coating thickness. The roughness spectra of specimen's crater after 16 min, discharge were obtained using a Talysuf5m-120 roughness tester as well.

Effect of nutrition education and traditional game-based physical activity interventions, on lipid profile improvement in overweight and obese children in West Java Indonesia

  • Yulia, Cica;Khomsan, Ali;Sukandar, Dadang;Riyadi, Hadi
    • Nutrition Research and Practice
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    • v.15 no.4
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    • pp.479-491
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    • 2021
  • BACKGROUND/OBJECTIVES: One ongoing effort to curtail dyslipidemia in school children is through lifestyle intervention. This study analyzes outcomes of the intervention of nutrition education and Javanese traditional game-based physical activity, on lipid profiles of overweight and obese children. SUBJECTS/METHODS: The experimental study consisted of three steps: data collection (October to December 2016), intervention processes (January to March 2017), and final report preparation (April to May 2017). This was a split-plot block study, enrolling a total of 72 subjects. Traditional game intervention (12 meetings) and nutrition education (9 meetings) was carried out within 3 months with material related to obesity. RESULTS: Our results showed no decrease in the levels of total cholesterol in the group receiving nutrition education (rise by 1.56 mg/dL), but when compared to subjects without intervention, total cholesterol levels experienced was increased. The group which did not receive physical activity showed increase in the total cholesterol, whereas the traditional game intervention group showed a decrease of 0.05 mg/dL total cholesterol at the end of the intervention. Nutrition education and physical activity interventions did not influence any reduction in the low-density lipoprotein cholesterol (LDL-C) levels, but rather showed a tendency to increase at the end of the intervention. However, the increase in LDL-c levels in the traditional game group was lower than in other intervention groups. Duncan's test indicated that the effect of nutrition education and physical activity interventions did not differ from the cut-off values of LDL-C and high-density lipoprotein cholesterol. CONCLUSIONS: Total cholesterol and triglyceride levels in the traditional game group tended to decrease at the end of the intervention, but the results did not differ much from other intervention groups. We deduce that nutrition education and traditional game-based physical activity interventions are not capable of improving blood lipid profiles in overweight and obese children within 3 months. It is necessary to increase the time of physical activity intervention to maintain the lipid profile in another study.

The Assessment on the Characteristics of Quantitative Image in Digora$\textregistered$ (Digora$\textregistered$에서 정량영상의 특성에 대한 평가)

  • Kim Jae-Duk
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.29 no.2
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    • pp.397-405
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    • 1999
  • Purpose: To clarify the usefulness and the limitation of Digora system/sup (R)/ by evaluating the physical characteristics as the quantitative image on Image Plate(Ip). Materials and Methods: Radiograms were taken by Heliodent MD(Siemens Co.. Germany) with the image plate for adult. Cu-step wedge as reference material. and three pieces of dry mandibular bone. Image analysis was performed by single color enhancement. density measurement with histogram. The relationship between the exposure conditions and the distribution of the pixel values of the image. the variation of pixel values of each step of Cu-step wedge at two different area and Cu-equivalent value of three pieces of dry mandibular bone measure by the conversion equation. Results: There was no linear relationship between the exposure condition and the average pixel value of the image. of which the distribution was not even. The pixel value differences between the center portion and the periphery were ranged from 60 to 70 in vertical plane and from 15 to 26 in horizontal plane. Two plot profile formed at two different areas of the Cu-step wedge were different. The measured Cu-equivalent values showed the discrepancy among the times of measurement. Conclusion: As above results. Image Plate(Ip) of Digora system/sup (R)/ showed the limitation as the quantitative image. The physical property of IP was expected to need to be compensated for the quantitative evaluation of the bone or others

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Pulse electric field-excited electron emission from Pb$(Zr_xTi_{1-x})O_3$ ceramics prepared by conventional solid state reaction (고상 반응법에 의해 제조된 Pb$(Zr_xTi_{1-x})O_3$ 세라믹스에서 펄스 전계에 의한 전자 방출)

  • Kwak, Sang-Hee;Kim, Tae-Heui;Park, Kyung-Bong;Kim, Chang-Soo
    • Proceedings of the KIEE Conference
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    • 1999.07d
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    • pp.1867-1869
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    • 1999
  • Pulse electric field induced electron emission from ferroelectrics has been studied with Pb$(Zr_xTi_{1-x})O_3$ ceramics with varying Zr/Ti ratio from 35/65 to 65/35, Electron emission was proved to be concentrated on the electrode edge by emission profile test and emission capture photographs. The 65/35 composition showed largest emission charge in lowest field and lowest emission threshold field. The emission characteristics are closely dependent on their ferroelectric properties in hysteresis curve. Electron emission charge increases with the polarization charge and emission threshold voltage is dependent on coercive field regardless of their composition. But dielectric constant has little relation with emission property. Electron emission charge increases exponentially with pulse electric field irrespective of composition. On the assumption that the surface potential is linear with the pulse electric field, electron emission can be regarded as a field emission at the electrode edge using Fowler-Nordheim plot of ln$(Q_e/E_{fe})$ to $1/E_{fe}$.

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