• Journal of Microbiology and Biotechnology
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• v.25 no.2
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• pp.255-267
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• 2015

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic debilitating disease affecting ruminants worldwide. In the present study, we aimed to determine the major gene networks and pathways underlying the immune response to MAP infection using whole-blood cells, as well as provide the potential transcriptional markers for identifying the status of MAP infection. We analyzed the transcriptional profiles of whole-blood cells of cattle identified and grouped according to the presence of MAP-specific antibodies and the MAP shed by them. The grouping was based on the results obtained by ELISA and PCR analyses as follows: i) Test1 group: MAP-negative results obtained by ELISA and positive results obtained by PCR; ii) Test2 group: MAP-positive results obtained by ELISA and negative results obtained by PCR; iii) Test3 group: MAP-positive results obtained by ELISA and positive results obtained by PCR; iv) uninfected control: MAP-negative results obtained both by ELISA and PCR analysis. The results showed down-regulated production and metabolism of reactive oxygen species in the Test1 group, activation of pathways related to the host-defense response against MAP (LXR/RXR activation and complement system) in the Test2 and Test3 groups, and anti-inflammatory response (activation of IL-10 signaling pathway) only in the Test3 group. Our data indicate a balanced response that serves the immune-limiting mechanism while the host-defense responses are progressing.

• The Journal of the Korea institute of electronic communication sciences
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• v.6 no.6
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• pp.951-956
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• 2011

CAN communication developed for communication between electric control devices in vehicle, was recently applied to automatic breaking devices, and can also be applied to field bus for production automation. Recently, field bus is introduced in engine control etc., for large ship. In this paper, cabin access control system is implemented, based on CAN communication. The cabin access control system based on CAN communication consists of access control server, embedded system based on ARM9, and micro-controller built-in CAN controller. The access control server can be able to manage overall access control system by accessing with manager. And embedded system adopted ARM9 processor transmits access information of RFID reader controller connected with CAN networks to server, also performs access control. The embedded system carry CAN frames to server, so it is used as gateway.

• 한국환경농학회:학술대회논문집
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• 2009.07a
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• pp.228-239
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• 2009

The observations on climate change show a clear increase in the temperature of the Earth's surface and the oceans, a reduction in the land snow cover, and melting of the sea ice and glaciers. The effects of climate change are likely to include more variable weather, heat waves, increased mean temperature, rains, flooding and droughts. The threat of climate change and global warming on human and animal health is now recognized as a global issue. This presentation is described an overview of the latest scientific knowledge on the impact of climate change on zoonotic diseases. Climate strongly affects agriculture and livestock production and influences animal diseases, vectors and pathogens, and their habitat. Global warming are likely to change the temporal and geographical distribution of infectious diseases, including those that are vector-borne such as West Nile fever, Rift Valley fever, Japanese encephalitis, bluetongue, malaria and visceral leishmaniasis, and other diarrheal diseases. The distribution and prevalence of vector-borne diseases may be the most significant effect of climate change. The impact of climate change on the emergence and re-emergence of animal diseases has been confirmed by a majority of countries. Emerging zoonotic diseases are increasingly recognized as a global and regional issue with potential serious human health and economic impacts and their current upward trends are likely to continue. Coordinated international responses are therefore essential across veterinary and human health sectors, regions and countries to control and prevent emerging zoonoses. A new early warning and alert systems is developing and introducing for enhancing surveillance and response to zoonotic diseases. And international networks that include public health, research, medical and veterinary laboratories working with zoonotic pathogens should be established and strengthened. Facing this challenging future, the long-term strategies for zoonotic diseases that may be affected by climate change is need for better prevention and control measures in susceptible livestock, wildlife and vectors in Korea. In conclusion, strengthening global, regional and national early warning systems is extremely important, as are coordinated research programmes and subsequent prevention and control measures, and need for the global surveillance network essential for early detection of zoonotic diseases.

• Journal of Plant Biotechnology
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• v.34 no.2
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• pp.81-93
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• 2007

Gas hydrates are known to form by physical interactions between host water and guest gas molecules and thus can be treated as a special type of icy materials. The gas hydrates are recently highlighted because of their use to future energy source even though they were discovered naturally in the deep-sea marine sediments a long time ago. However, the present and future urgent task is to develop the efficient and safe production technology for recovering methane from gas hydrates. Here, we propose one of potential recovery processes using swapping phenomenon occurring between gaseous carbon dioxide and methane hydrate deposits. Such a swapping process provide several technological and economical advantages over conventional processes. The carbon dioxide can be directly sequestered into methane hydrate layer and simultaneously methane can be produced with a high recovery rate more than 90%. In addition, the icy powders can be effectively used as a new medium for storing hydrogen. To increase hydrogen storage capacity the icy hydrate networks need to be redesigned to create the more empty cages in which hydrogen gas can be enclathrated. Functionalized icy materials might be used in a variety of energy and environmental fields.

• Journal of Korean Society on Water Environment
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• v.32 no.6
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• pp.511-519
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• 2016

National Institute of Environmental Research (NIER) has developed the Korean Reach File (KRF) for scientific and systematic analysis of variables related to water quality, pollutant sources and aquatic ecosystems in consideration of steam reach networks. The KRF provides a new framework for data production, storage, management and analysis for water related variables in relation to spatial characteristics, connections, and topologies of stream reaches. However, the current version of KRF (ver.2) has limited applicability because its nodes include not only the stream points based on topological characteristics but also those based on water quality monitoring stations, which may undermine its generality. In this study, a new version of KRF (ver.3) was designed and established to overcome the weak point of version 2. The version 3 is a generalization of the old KRF graphic data and it integrates the attribute data while separating it from the graphic data to minimize additional work that is needed for data association and search. We tested the KRF (ver.3) on actual cases and convenience and adaptability for each application was verified. Further research should focus on developing a database link model and real-world applications that are targeted to process event data.

• Journal of Science and Technology Studies
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• v.8 no.2
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• pp.1-26
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• 2008

This essay explores the possibility of risk epistemology based on STS perspective. The starting point is the modern society's dilemma that the more technoscience has been developed, the more modern society has become riskier. The conventional risk epistemology, based on modernist dualism, has a tendency to be negligent of the relationship between risk society and technoscience, since it has only paid attention to either side of objectivity of risk or context of risk. In contrast, STS perspective on risk makes a point of focusing on the need of constructing the comprehensive risk epistemology, instead of the traditional approach based on modernist dualism. Now, this perspective goes ahead through "bridging" between objective risk(nature) and contextual risk(society) toward co-production of risk, as a result that we can no more turn our head from the emergence of new hybrids and, in turn, increase of complexity of heterogeneous networks. As such I suggest the concept of technosphere so as to reflect and display these characteristics of this perspective, and assess the potentiality of the concept.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.11
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• pp.1700-1713
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• 2018

Objective: The aim of this study was to verify the usefulness of artificial neural networks (ANN), multivariate adaptive regression splines (MARS), naïve Bayes classifier (NBC), general discriminant analysis (GDA), and logistic regression (LR) for dystocia detection in Polish Holstein-Friesian Black-and-White heifers and cows and to indicate the most influential predictors of calving difficulty. Methods: A total of 1,342 and 1,699 calving records including six categorical and four continuous predictors were used. Calving category (difficult vs easy or difficult, moderate and easy) was the dependent variable. Results: The maximum sensitivity, specificity and accuracy achieved for heifers on the independent test set were 0.855 (for ANN), 0.969 (for NBC), and 0.813 (for GDA), respectively, whereas the values for cows were 0.600 (for ANN), 1.000 and 0.965 (for NBC, GDA, and LR), respectively. With the three categories of calving difficulty, the maximum overall accuracy for heifers and cows was 0.589 (for MARS) and 0.649 (for ANN), respectively. The most influential predictors for heifers were an average calving difficulty score for the dam's sire, calving age and the mean yield of the farm, where the heifer was kept, whereas for cows, these additionally included: calf sex, the difficulty of the preceding calving, and the mean daily milk yield for the preceding lactation. Conclusion: The potential application of the investigated models in dairy cattle farming requires, however, their further improvement in order to reduce the rate of dystocia misdiagnosis and to increase detection reliability.

• Journal of the Korean association of regional geographers
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• v.11 no.2
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• pp.233-246
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• 2005

This paper aims to explore the innovation milieu of red-pepper agro-industry in Bonghwa County, in the northern part of Gyeongbuk Province, and suggest policy recommendations for bringing up local agro-industry from a cluster perspective. It turns out that the capabilities of Bonghwa red-pepper agro-industry to innovate are remarkably weak let alone soft infrastructures such as learning networks between innovation agents and social capital. In this sense Bonghwa red-pepper agro-industry can be viewed as an agricultural area simply specialized in production sector rather than a kind of agro-industry cluster. For moving up Bonghwa red pepper industry into an innovative cluster, the paper suggests that the policy makers need to focus on cultivating local learning communities, building a region-wide incorporated brand, promoting the local agricultural technology centre as a network hub of cluster and fostering the functional links between universities and local innovation agents, covering farmers, agricultural organizations, agro-food producers and the local government.

• Journal of the Korean Geographical Society
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• v.38 no.4
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• pp.518-534
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• 2003

A number of previous studies have maintained that information technologies, due to their ability to overcome distance, can nurturing an innovative class of polycentric urban configurations, i.e., network cities. The present study intends to clarify whether any network relationship has recently been emerged among Korean cities by the advancement of information technology. The analyses focused on the geography of Korean national domains (.kr domains), and the hyperlink associations among three major types of domains, namely commercial, academic, and organizational domains. The study findings altogether indicate that the advancement of global economy and information era appears to be enhancing, rather than reducing the status of primate city. Seoul dominates the entire nation, forming an enclave in the production and consumption of information. Only the domains of educational institutes show network-like relations among local centers to a certain extent. The paper concludes with a discussion on the implications of the findings for future research and ‘spatial’ policy measures.

• Journal of Plant Biotechnology
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• v.38 no.2
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• pp.117-124
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• 2011

Considering that the world population is expected to total 9 billion by 2050, it will clearly be necessary to sustain and even accelerate the rate of improvement in crop productivity. In the 21st century, we now face another, perhaps more devastating, environmental threat, namely climate change, which could cause irreversible damage to agricultural ecosystem and loss of production potential. Enhancing intrinsic yield, plant abiotic stress tolerance, and pest and pathogen resistance through agricultural biotechnology will be a critical part of feeding, clothing, and providing energy for the human population, and overcoming climate change. Development and commercialization of genetically engineered crops have significantly contributed to increase of crop yield and farmer's income, decrease of environmental impact associated with herbicide and insecticide, and to reduction of greenhouse gas emissions from this cropping area. Advances in plant genomics, proteomics and system biology have offered an unprecedented opportunities to identify genes, pathways and networks that control agricultural important traits. Because such advances will provide further details and complete understanding of interaction of plant systems and environmental variables, biotechnology is likely to be the most prominent part of the next generation of successful agricultural industry. In this article, we review the prospects for modification of agricultural target traits by genetic engineering, including enhancement of photosynthesis, abiotic stress tolerance, and pest and pathogen resistance associated with such opportunities and challenges under climate change.