• 제목/요약/키워드: Production Control

검색결과 9,614건 처리시간 0.038초

홍의 추출물의 항염작용 및 그 기전 연구 (The anti-imflammatory effect and the mechanism of Formica yessensis extraction)

  • 김종민;김승형;양원경;정택근;김세란;황성준;유화승
    • 혜화의학회지
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    • 제25권1호
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    • pp.71-86
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    • 2016
  • Objective : Hongyi (Formica yessensis) is the dried insect of fomicidae. In previous studies, it appeared possibilities on anti-thrombosis, preventing atherosclerosis, treating rheumatoid disease, and inhibiting hela cell. In this study, we investigated anti-inflammatory effects and mechanism of Hongyi. Methods : Hongyi A was extracted by water and made dried powder. Hongyi B was extracted by ethanol and made dried powder. We measured Nitric Oxide (NO) production on the mouse macrophages (RAW 264.7), mouse vascular endothelial cell (MOVAS) and human vascular endothelial cell (HUVEC) for anti-inflammatory effect. In addition, we conducted reverse transcription reaction (RT-PCR) for investigating the mechanism. Results : In RAW 264.7 macrophages stimulated by LPS, Hongyi A ($100{\mu}g/m{\ell}$) decreased NO production compared with LPS $2{\mu}g/ml$ control group with statistical significance (p<0.05). Hongyi A (50, $100{\mu}g/m{\ell}$) also decreased NO production compared with LPS $4{\mu}g/ml$ control group with statistical significance (p<0.01). Hongyi B (50, $100{\mu}g/m{\ell}$) decreased NO production compared with LPS $2{\mu}g/ml$ control group with statistical significance (p<0.01). Hongyi B (10, 50, $100{\mu}g/m{\ell}$) also decreased NO production compared with LPS $4{\mu}g/ml$ control group with statistical significance (p<0.01, p<0.001, p<0.001). In the MOVAS, Hongyi A and B increased NO production compared with control group. In the HUVEC, Hongyi B increased NO production compared with control group. The expression of NF-${\kappa}B$ in 12-hours MOVAS culture was decreased by Hongyi A and B (10, $50{\mu}g/ml$) compared with control group, but expression of $I{\kappa}B$ was increased. In the 24-hours MOVAS culture, expression of $I{\kappa}B$ was significantly increased. The expression of NF-${\kappa}B$ in 12-hours HUVEC culture was decreased by Hongyi A and B compared with control group, but expression of $I{\kappa}B$ was increased. Hongyi B also increased eNOS mRNA gene expression. Conclusions : Hongyi A and B showed anti-inflammatory effect in mouse macrophages with the activation of vascular endothelial cell through NO production in MOVAS and HUVEC repectively. Honyi B showed superior effect than Hongyi A, but additonal mechanism study should be conducted.

Utilization of Tobacco Sucker Control Agents in China

  • Li, Hu-lin
    • 한국연초학회지
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    • 제25권2호
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    • pp.154-159
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    • 2003
  • Using sucker agents for tobacco can lead some advantages including saving labor, increasing yield and reducing the spread of diseases. At present, the sucker control agents used in China mainly depended on importing. The agents includes two groups, systemics (Maleic hydrazide: MH, etc) and partial systemics (Butralin, Flumetralin, Pendimethalin, etc). Now, Pendimethalin(a.i. 33%, wp) was used extensively all over the tobacco field in China. Sucker control agents will also be used for tobacco production in China. Because of the high price of the imported agents, China has studied on the domestic production of tobacco sucker control agents and has made some progresses.

Intelligent Lighting Control using Wireless Sensor Networks for Media Production

  • Park, Hee-Min;Burke, Jeff;Srivastava, Mani B.
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제3권5호
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    • pp.423-443
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    • 2009
  • We present the design and implementation of a unique sensing and actuation application -- the Illuminator: a sensor network-based intelligent light control system for entertainment and media production. Unlike most sensor network applications, which focus on sensing alone, a distinctive aspect of the Illuminator is that it closes the loop from light sensing to lighting control. We describe the Illuminator's design requirements, system architecture, algorithms, implementation and experimental results. The system uses the Illumimote, a multi-modal and high fidelity light sensor module well-suited for wireless sensor networks, to satisfy the high-performance light sensing requirements of entertainment and media production applications. The Illuminator system is a toolset to characterize the illumination profile of a deployed set of fixed position lights, generate desired lighting effects for moving targets (actors, scenic elements, etc.) based on user constraints expressed in a formal language, and to assist in the set up of lights to achieve the same illumination profile in multiple venues. After characterizing deployed lights, the Illuminator computes optimal light settings at run-time to achieve a user-specified actuation profile, using an optimization framework based on a genetic algorithm. Uniquely, it can use deployed sensors to incorporate changing ambient lighting conditions and moving targets into actuation. Experimental results demonstrate that the Illuminator handles various high-level user requirements and generates an optimal light actuation profile. These results suggest that the Illuminator system supports entertainment and media production applications.

PHB 생산의 최적화 및 제어를 위한 이단유가식 배양의 전산모사 (A Simulation Study of Two-stage Fed-batch Culture for Optimization and Control of PHB Production)

  • 이재호;이용우;유영제
    • 한국미생물·생명공학회지
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    • 제20권6호
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    • pp.668-676
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    • 1992
  • Alcaligenes eutrophus에 의한 poly-Beta-hydroxybuty-rate(PHB) 생산을 최적화하기 위해서 1단계에서는 성장을 최대화하고, 2단계에서는 생산을 최대화하는 이단 유가식 배양을 채택하였다. 성장단계에서 탄소원과 질소원의 최적농도는 회분식 배양 모델로부터 결정되었는데, 각기 16.64g/l와 0.54g/l이었다. 생산단계에서 질소원의 경우, 유가식 배양실험을 통해 0.07g/l가 최적인 것으로 나타났다. 탄소원의 최적농도는 모사로부터 결정되었고 이때 최적 전환시간도 함께 결정되었다. 생산공정의 제어를 위하여 시간지연을 고려한 적응비례 되먹임제어를 이용한 결과, 탄소원 농도 및 질소원농도를 최적의 상태로 유지시킬 수 있었다.

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PRODUCTION RESPONSES OF CROSSBRED HOLSTEIN MILKING COWS FED UREA-TREATED RICE STRAW AT THREE DIFFERENT FIBER LEVELS

  • Promma, S.;Jeenklum, P.;Indratula, T.
    • Asian-Australasian Journal of Animal Sciences
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    • 제6권4호
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    • pp.509-514
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    • 1993
  • The experiment was conducted to determine the effect of different fiber levels on milk production of crossbred Holstein milking cows fed urea-treated rice straw (UTS) as a roughage. Eight cows were allotted into 2 squares of 4 cows each with 4 treatments by a balanced design. The treatments were 17%, 22%, and 24% crude fiber (CF) diets and Thai feeding system (free choice of roughage and 1 kg of concentrates/2 kg of milk) as a control. Body weight change was not significantly different among the treatments during the experiment. Milk production (4% FCM) and milk protein content wee not different among the treatments, but milk fat content was low in the 17% CF group and high in the control group. Cows fed the 17% CF diet consumed less UTS and more concentrates than the others, and consequently total DM intake was not different among the treatments. The feed conversion ratio was significantly higher in the control. Feed cost per kg milk was lowest in the control and highest in the 17% CF diet. The fiber content of the diet would be more than 17%, preferably 22-24% for normally producing Thai crossbred Holstein cows when the UTS was fed as a main roughage source.

목향조기산(木香調氣散) 추출물이 뇌허혈 흰쥐의 뇌혈류개선에 미치는 작용기전 (Mechanism of Mokhyangjoki-san Extract on the Improvement in Cerebral Blood Flow in Ischemic Rats)

  • 심익현;최찬헌;김영목;윤영제;정현우
    • 동의생리병리학회지
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    • 제25권5호
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    • pp.807-815
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    • 2011
  • This study was designed to investigate the effects of Mokhyangjoki-san extract (MJS) on the improvement in cerebral blood flow (rCBF) in cerebral ischemic rats, and further to determine cytokines production (IL-1${\beta}$, TNF-${\alpha}$, IL-10, TGF-${\beta}$) of MJS. The results in cerebral ischemic rats were as follows ; The rCBF was significantly and stably increased by MJS (10 mg/kg, i.p.) during the period of cerebral reperfusion, which contrasted with the findings of rapid and marked increase in control group. In cytokine production in serum from femoral arterial blood 1 hr after middle cerebral arterial occlusion, MJS significantly decreased IL-1${\beta}$ and TNF-${\alpha}$ production, and increased IL-10 production compared with control group. In cytokine production in serum from femoral arterial blood 1 hr after reperfusion, MJS significantly decreased IL-1${\beta}$ and TNF-${\alpha}$ production compared with control group. IL-10 and TGF-${\beta}$1 production in MJS group were significantly increased compared with control group. These results suggested that MJS significantly and stably increased rCBF by inhibiting the production IL-1${\beta}$ and TNF-${\alpha}$, and accelerating that of IL-10 and TGF-${\beta}$. The result in nerve cells was as follows ; MJS significantly inhibited lactate dehydrogenase activity in vitro in a dose-dependent manner. This result suggested that MJS prevented the neuronal death.

Quenching rate controlled Laser Annealing (QLA) for poly-Si TFT fabrication

  • Han, Gyoo-W.;Alexander, Voronov;Ryu, S.G.;Kim, H.S.;Roh, C.L.
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2005년도 International Meeting on Information Displayvol.II
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    • pp.897-897
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    • 2005
  • We report QLA (Quenching-rate controlled Laser Annealing) system as new concept using pulsed DPSSL and CW lasers. This process can control temperature quenching-rate of poly-Si crystallization by additional CW laser and fabricate high quality poly-Si with faster scanning speed than conventional processes. In this paper, QLA system, the experimental results and theoretical discussion will be introduced.

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In vitro Screening of Essential Oil Active Compounds for Manipulation of Rumen Fermentation and Methane Mitigation

  • Joch, M.;Cermak, L.;Hakl, J.;Hucko, B.;Duskova, D.;Marounek, M.
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권7호
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    • pp.952-959
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    • 2016
  • The objective of this study was to investigate the effects of 11 active compounds of essential oils (ACEO) on rumen fermentation characteristics and methane production. Two trials were conducted. In trial 1, ACEO (eugenol, carvacrol, citral, limonene, 1,4-cineole, p-cymene, linalool, bornyl acetate, ${\alpha}$-pinene, and ${\beta}$-pinene) at a dose of $1,000{\mu}L/L$ were incubated for 24 h in diluted rumen fluid with a 70:30 forage:concentrate substrate (16.2% crude protein; 36.6% neutral detergent fiber). Three fistulated Holstein cows were used as donors of rumen fluid. The reduction in methane production was observed with nine ACEO (up to 86% reduction) compared with the control (p<0.05). Among these, only limonene, 1,4-cineole, bornyl acetate, and ${\alpha}$-pinene did not inhibit volatile fatty acid (VFA) production, and only bornyl acetate produced less methane per mol of VFA compared with the control (p<0.05). In a subsequent trial, the effects on rumen fermentation and methane production of two concentrations (500 and $2,000{\mu}L/L$) of bornyl acetate, the most promising ACEO from the first trial, were evaluated using the same in vitro incubation method that was used in the first trial. In trial 2, monensin was used as a positive control. Both doses of bornyl acetate decreased (p<0.05) methane production and did not inhibit VFA production. Positive effects of bornyl acetate on methane and VFA production were more pronounced than the effects of monensin. These results confirm the ability of bornyl acetate to decrease methane production, which may help to improve the efficiency of energy use in the rumen.

Applications of Goods Mutation Control Form in Accounting Information System: A Case Study in Sumber Indah Perkasa Manufacturing, Indonesia

  • ARIF, Donny;YUCHA, Nikma;SETIAWAN, Setiawan;OKTARINA, Dian;MARTAH, Varid;MUTTAQIIN, Ninnasi
    • The Journal of Asian Finance, Economics and Business
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    • 제7권8호
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    • pp.419-424
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    • 2020
  • This study analyzes the new GMCF method applied by the company with the aim to find out how the production of Accounting Information Systems (AIS) implemented by the company can be managed properly. The study also seeks to find out whether the company needs new system support facilities to facilitate the production performance reporting process of each division and evaluate the performance of GMCF systems in the company. The methods used are descriptive analysis techniques and statistical tests of Paired Sample T-Test comparison; this study uses production data of each unit of a product with random sampling to determine the level of product damage and compare production with the GMCF system and prior to using it. The results of the analysis found that the application of goods mutation control forms (GMCF) greatly influenced the smooth production reporting process, which resulted in an increase in achieving production targets and reducing the risk of product damage during the production process. The company also benefits from the efficiency of production costs when using the GMCF system and can quickly design policies for products that are damaged during the production process. In addition, the company can have damaged products repaired faster than before.

유연 생산셀의 계층적 제어와 지능형 스케쥴 (hierarchical Control and Intelligent Scheduling of Flexible Manufacturing Cell)

  • 서기성;이노성;안인석;박승규;우광방
    • 대한전기학회논문지
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    • 제43권3호
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    • pp.492-503
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    • 1994
  • In this study, the control and scheduling of the flexible manufacturing cell (FMC) is discussed, which can perform the mixed production and relieve the effect of machine failure. The control of the FMC isvery complex task due to the property of multiple jobs and the dynamically changing states. For effective control of proposed FMC, the hierarchical scheme is introduced and the functions of each levels are defined. Especially for the control functions of shop floor level and cell level, the intelligent scheduler is implemented. To show the efficiency of the intelligent scheduler, the production method fo the existing assembly lines was evaluated and compared with the proposed intelligent FMC method. The results from the production performance show that the proposed method is superior to the existing method in various performance indices.