• 한국산업융합학회 논문집
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• 제26권5호
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• pp.885-894
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• 2023

Setting RAM target value for a defense system plays a crucial role in the development and design phases and the production phase as well. It is apparent that the achieved RAM target value can help maximizing the combat capability of a defense system and improving its performance throughout the system's life cycle from acquisition phase to disposal. Usually a defense system operates according to its OMS/MP (Operational Mode Summary / Mission Profile) and it consists of several subsystems which are supposed to be operated at each utilization rate under its operating conditions and the mission profiles assigned. In this study, a method of setting RAM target value is proposed for a defense system that are composed of several independent subsystems considering their utilization rates and the mission profiles assigned. And the case study of applying the proposed method of setting RAM target value to system A is dealt with.

• 한국표면공학회지
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• 제57권3호
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• pp.165-178
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• 2024

In semiconductor memory device manufacturing, the capability for high aspect ratio contact (HARC) etching determines the density of memory device. Given that there is no standardized definition of "high" in high aspect ratio, it is crucial to continuously monitor recent technology trends to address technological gaps. Not only semiconductor memory manufacturing companies such as Samsung Electronics, SK Hynix, and Micron but also semiconductor manufacturing equipment companies such as Lam Research, Applied Materials, Tokyo Electron, and SEMES release annual reports on HARC etching technology. Although there is a gap in technological focus between semiconductor mass production environments and various research institutes, the results from these institutes significantly contribute by demonstrating fundamental mechanisms with empirical evidence, often in collaboration with industry researchers. This paper reviews recent studies on HARC etching and the study of dielectric etching in various technologies.

• Journal of Forest and Environmental Science
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• 제40권2호
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• pp.73-81
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• 2024

As a phreatophyte, pistachio (Pistacia vera L.) is widely grown in water-limited conditions and recognized as an economically valuable crop in semi-arid regions. In Tajikistan, pistachio grows naturally and artificially in 79,000 ha, but the nut yield is very low due to less-developed plantation technologies. In this study, differences in pistachio plantation technologies of the major pistachio-producing countries and Tajikistan were analyzed to suggest ways to improve plantation technologies in Tajikistan. In the major pistachio-producing countries such as Iran, the United States and Turkey, seedlings of high nut-yielding varieties are grafted before planting. As a result, annually 349-4,479 kg ha^-1 of nuts are harvested in those countries. On the other hand, Tajikistan annually produces only 0.6-3.7 kg ha^-1. While seven suitable high nut-yielding varieties (Albina, Dangarinka, Saboh, Green girl, Mountain pearl, October, and Orzu) have been identified as suitable for Tajikistan's environment, the plantation area with grafted individuals using these varieties is limited to only 1.5 ha, necessitating widespread adoption. The low utilization of the high nut-yielding varieties is attributed to the lack of grafting specialists and skills, which have hindered increasing pistachio nut production in Tajikistan. Therefore, improving the basic capability of pistachio grafting should be prioritized to expand the economic profits from the pistachio forests in Tajikistan.

• 방송공학회논문지
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• 제14권6호
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• pp.783-795
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• 2009

본 연구는 디지털기술과 광대역네트워크기술의 발달에 따라 DMB, IPTV 등 신규매체가 등장함에도 불구하고 다채널방송들은 거의 동일한 내용의 콘텐츠를 제공하는데 대한 문제인식을 토대로, 플랫폼 차별화를 위해 필요한 디지털방송 콘텐츠의 수요량 및 공급량을 분석하였다. 콘텐츠 수요량은 정부의 정책적 결정에 따라 예상되는 각 매체의 채널수를 기반으로 최대, 보통, 최소의 3개 시나리오를 토대로 분석하였고, 콘텐츠 공급량은 각 매체 및 주요 방송채널사용사업자의 본방송 및 재방송비율, 그리고 지상파 방송 및 주요PP 등의 방송콘텐츠 제작 능력을 제작시설 가동률이 100%, 75%, 50%의 3가지 시나리오에 따라 분석하였다. 분석결과 최대 시나리오의 경우 연간 453,484시간의 신규 콘텐츠가 요구되며, 전체 제작시설 가동률이 100%로 가정하더라도 72,852시간의 콘텐츠만 제작 가능함으로써, 방송 콘텐츠의 수요량과 공급량의 불균형이 극심함을 알 수 있었다. 이러한 결과는 플랫폼과 네트워크 산업의 확장에 주력해온 정부 정책의 결과로 해석되며, 콘텐츠 산업을 활성화할 수 있는 정책마련이 필요하다는 것을 의미한다.

• 한국토양비료학회지
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• 제48권2호
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• pp.125-131
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• 2015

Phenyllactic acid (PLA) which is known as antimicrobial compound can be synthesized through the reduction of phenylpyruvic acid (PPA) by lactate dehydrogenase (LDH) of lactic acid bacteria (LAB). LAB producing PLA was isolated from Korea Kimchi and identified to Lactobacillus plantarum SJ21 by 16 rRNA gene sequence analysis. Cell-free supernatant (CFS) from L. plantarum SJ21 was assessed for both the capability to produce the antimicrobial compound PLA and the antifungal activity against four fungal pathogens (Rhizoctonia solani, Aspergillus oryzae, Botrytis cinerea, and Collectotricum aculatum). PLA concentration was investigated to be 3.23mM in CFS when L. plantarum SJ21 was grown in MRS broth containing 5mM PPA for 16 h. PLA production also could be promoted by the supplement of PPA and phenylalanine in MRS broth, but inhibited by the supplement of 4-hydroxyphenylpyruvic acid and tyrosine as precursors. Antifungal activity demonstrated that all fungal pathogens were sensitive to 5% CFS (v/v) of L. plantarum SJ21 with average growth inhibitions ranging from 27.32% to 69.05% (p<0.005), in which R. solani was the most sensitive to 69.05% and followed by B. cinerea, C. aculatum, and A. oryzae. The minimum inhibitory concentration (MIC) for commercial PLA was also investigated to show the same trend in the range from $0.35mg\;mL^{-1}$ (2.11 mM) to $0.7mg\;mL^{-1}$ (4.21 mM) at pH 4.0. The inhibition ability of CFS against the pathogens was not affected by heating or protease treatment. However, pH modification in CFS to 6.5 caused an extreme reduction in their antifungal activity. These results may indicate that antifungal activities in CFS were caused by acidic compounds like PLA or organic acids rather than proteins or peptides molecules.

• 대한미생물학회지
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• 제35권3호
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• pp.203-214
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• 2000

Porphyromonas gingivalis has been implicated in periodontal diseases. Accumulating evidence suggests that cardiovascular disease is the most prevalent medical problem in patients with periodontal diseases. In order to check the possibility that P. gingivalis is involved in coronary heart disease, the present study was performed to observe P. gingivalis adherence and invasion of human coronary artery endothelial cells (HCAEC) and production of cytokines and growth factors by HCAEC upon P. gingivalis infection. $^3H$-labeled P. gingivalis 381 was incubated with HCAEC for 90 min. The radioactivity of the washed HCAEC was a measure of the absorbed (adhering and invading) P. gingivalis. The absorption radioactivity of the HCAEC infected by P. gingivalis was determined to be 59.58% of the input bacterial cells. In contrast, the absorption radioactivity of the cells infected by S. gordonii Challis which was employed as a control was negligible (0.59%). DPG3, a P. gingivalis mutant defective of fimbriae, appeared to be impaired to some extent in capability of adherence/invasion as compared to that of the parental strain 381, showing 43.04% of the absorption radioactivity. The absorption radioactivity of the HCAEC infected by P. gingivalis 381 in the presence of excessive fimbriae at the concentrations of $50\;{\mu}g$ and $100\;{\mu}g/ml$ was 57.27 and 45.44%, respectively. Invasion of HCAEC by P. gingivalis 381 was observed by an antibiotic (metronidazole) protection assay and transmission electron microscopy (TEM). In the antibiotic protection assay, invasion by the bacterium was measured to be 0.73, 1.09, and 1.51% of the input bacterial cells after incubation for 30, 60, and 90 min, respectively. Invasion by DPG3 was shown to be 0.16% after 90-min incubation. In comparison of invasion efficiency at 90 min of the incubation, the invasion efficiency of DPG3 was 0.37% while that of its parental strain 381 was 2.54%. The immunoblot analysis revealed fimbriae of P. gingivalis did not interact with the surface of HCAEC. These results suggest that fimbriae are not the major contribution to the adherence of P. gingivalis to HCAEC but may be important in the invasion of HCAEC by the bacterium. The presence of cytochalasin D ($1\;{\mu}g/ml$) and staurosporine ($1\;{\mu}M$) reduced the invasion of HCAEC by P. gingivalis 381 by 78.86 and 53.76%, respectively, indicating that cytoskeletal rearrangement and protein kinase of HCAEC are essential for the invasion. Infection of P. gingivalis induced HCAEC to increase the production of TNF-${\alpha}$. by 60.6%. At 90 min of the incubation, the HCAEC infected with P. gingivalis cells was apparently atypical in the shape, showing loss of the nuclear membrane and subcellular organelles. The overall results suggest that P. gingivalis may cause coronary heart disease by adhering to and invading endothelial cells, and subsequently damaging the cells.

• 한국초지조사료학회지
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• 제30권3호
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• pp.199-204
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• 2010

본 시험은 신품종 톨 페스큐를 육성하기 위하여 1999년부터 2007년까지 국립축산과학원 초지사료과에서 수행되었다. 톨 페스큐 신품종 '그린마스터'는 6배체 품종으로서 엽은 녹색이며, 출수기가 5월 14일경이며 풍엽성이 우수한 품종이었다. 4개 지역평균 건물수량은 '그린마스터' 19,156 kg/ha로서 대비품종인 'Fawn' 보다 11% 많았으며, 지역별로는 4개 지역 모두에서 'Fawn' 보다 생산성이 우수하였다. '그린마스터'의 사료가치는 조단백질 함량이 13.6%, 건물소화율이 51.1%, 가소화양분총량(TDN)이 60.3 %, NDF (중성세제불용섬유)가 66.1%, ADF(산성세제불용섬유)는 36.2%로서 Fawn과 비슷한 사료가치를 나타내었다. 특히, '그린마스터'는 'Fawn' 보다 재생력, 내병성 및 내하고성이 우수하여 영속성이 좋은 품종이며 한번 조성하여 여러 해 동안 이용하는 초지조성에 알맞은 품종으로서 우리나라 전국에서 재배적응성이 우수한 품종으로 사료된다.

• 한국초지조사료학회지
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• 제35권1호
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• pp.26-30
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• 2015

본 시험은 엔도파이트 프리 톨 페스큐 신품종을 개발하기 위하여 2008년부터 2014년까지 농촌진흥청 국립축산과 학원 초지사료과에서 수행되었다. 톨 페스큐 신품종 '그린마스터2호'는 6배체 품종으로서 잎은 녹색이며, 출수기가 5월 16일경으로서 대비품종인 'Fawn' 보다 5일 늦은 중생품종이고, 출수기에 초장은 82.5 cm 정도이다. 지역적응시험 4개 지역평균 건물수량은 '그린마스터2호'가 15.1톤/ha로서 대비품종인 'Fawn' 보다 29% 많았으며, 지역별로는 4개 지역 모두에서 'Fawn' 보다 생산성이 우수하였다. '그린마 스터2호'의 사료가치는 조단백질(CP) 함량이 13.9%, 건물소화율(IVDMD)이 69.9%, 가소화양분총량(TDN)이 63.8%, 중성세제불용섬유(NDF)가 59.4%, 산성세제불용섬유(ADF) 는 33.5%로서 Fawn과 대등하였다. '그린마스터2호'는 엔도파이트에 감염되지 않는 품종이면서 'Fawn' 보다 국내 기후환경 적응성과 영속성이 우수하여 초지조성에 알맞은 품종으로서 우리나라 전국에서 재배 가능하다.

• Journal of Construction Engineering and Project Management
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• 제5권2호
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• pp.11-15
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• 2015

The Last PlannerSystem (LPS) has been implemented on construction projects to increase work flow reliability, a precondition for project performance againstproductivity and progress targets. The LPS encompasses four tiers of planning processes:master scheduling, phase scheduling, lookahead planning, and commitment / weeklywork planning. This research highlights deficiencies in the current implementation of LPS including poor lookahead planning which results in poor linkage between weeklywork plans and the master schedule. This poor linkage undetermines the ability of theweekly work planning process to select for execution tasks that are critical to projectsuccess. As a result, percent plan complete (PPC) becomes a weak indicator of project progress. The purpose of this research is to improve lookahead planning (the bridgebetween weekly work planning and master scheduling), improve PPC, and improve theselection of tasks that are critical to project success by increasing the link betweenShould, Can, Will, and Did (components of the LPS), thereby rendering PPC a betterindicator of project progress. The research employs the case study research method to describe deficiencies inthe current implementation of the LPS and suggest guidelines for a better application ofLPS in general and lookahead planning in particular. It then introduces an analyticalsimulation model to analyze the lookahead planning process. This is done by examining the impact on PPC of increasing two lookahead planning performance metrics: tasksanticipated (TA) and tasks made ready (TMR). Finally, the research investigates theimportance of the lookahead planning functions: identification and removal ofconstraints, task breakdown, and operations design.The research findings confirm the positive impact of improving lookaheadplanning (i.e., TA and TMR) on PPC. It also recognizes the need to perform lookaheadplanning differently for three types of work involving different levels of uncertainty:stable work, medium uncertainty work, and highly emergent work.The research confirms the LPS rules for practice and specifically the need to planin greater detail as time gets closer to performing the work. It highlights the role of LPSas a production system that incorporates deliberate planning (predetermined andoptimized) and situated planning (flexible and adaptive). Finally, the research presents recommendations for production planningimprovements in three areas: process related, (suggesting guidelines for practice),technical, (highlighting issues with current software programs and advocating theinclusion of collaborative planning capability), and organizational improvements(suggesting transitional steps when applying the LPS).

• 대한화장품학회지
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• 제42권3호
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• pp.235-245
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• 2016

본 연구에서는 히알루론산나트륨(sodium hyaluronate, HA)을 효소 분해하여 분자량 크기(1, 10, 50, 100, 660, 및 1500 kDa) 별로 제조한 뒤 콜라겐 합성 및 항염증 활성에 미치는 영향과 피부투과도를 조사하였다. 이들 HA는 인간피부세포인 Hs68 세포에 세포독성을 나타내지 않았다. 콜라겐 생합성능은 1500 kDa, 50, kDa HA가 각각 59, 50%로 콜라겐 생합성 촉진능이 우수한 것으로 나타났다. 분자량 크기에 따른 HA의 피부투과도를 측정한 결과 660 또는 1500 kDa의 HA은 2% 미만의 미미한 투과율을 보였으나, 저분자 HA (1, 10, 또는 50 kDa)은 시간이 지남에 따라 투과율이 증가하는 것을 확인하였다. 마우스 대식세포인 RAW 264.7 세포에서 HA 분자량 크기에 따른 항염증 효과를 확인한 결과, 50 kDa HA가 농도 의존적으로 nitric oxide 및 tumor necrosis factor-${alpha}$ 합성을 저해하여 다른 분자량의 HA (1, 10, 및 100 kDa)에 비해 가장 큰 항염증 효능을 나타냈다. 현재까지 효소(hyaluronidase) 처리하여 제조된 다양한 크기의 분자량(1, 10, 50, 100, 660, 1500 kDa)의 HA 중 50 kDa HA가 collagen의 합성, 항염증 및 피부 흡수도에 대한 종합적인 평가를 한 사례는 없었다. 따라서 이러한 연구결과는 50 kDa의 HA가 인간피부세포에서 콜라겐 합성을 증진시키고, 피부 투과율을 높으며 피부 주름을 유발하는 염증반응을 억제함으로써 피부노화 및 주름 개선용 화장품소재로 개발될 수 있는 가능성을 보여준다.