• The Journal of Asian Finance, Economics and Business
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• v.9 no.8
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• pp.123-134
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• 2022

In 2021 One Tambon One Product (OTOP) food products reached $3,447 billion domestically and $200 million internationally. Mirroring Japan's highly successful OVOP (One Village One Product) poverty reduction and rural employment program, Thailand's OTOP program has since become a global model of success as well. From May through June 2022, OTOP snack food vendor entrepreneurs were contacted and asked to contribute their opinions about what factors affected their enterprise's food product quality. Using systematic random sampling across six Thai regions, 311 export entrepreneurs, production managers, and marketing managers participated. The results revealed that product innovation (PDTI), process innovation (PCSI), packaging design (PKD), and the 4P marketing mix (4PMM) all positively influenced OTOP snack food product quality (PDQ), which, when combined, had a total effect R² value of 27%. Also, the latent variable TE values for PDTI, PKD, 4PMM, and PCSI, were 0.38, 0.29, 0.22 and 0.11, respectively. Seven of the nine hypotheses examined were supported, with packaging design (PKD) determined to have the greatest influence on the 4P marketing mix (4PMM).

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.304-304
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• 2009

We may need to consider 'display' interface and product design as distinct from traditional user- and technologydriven product design. Technology-dominated product development may lead users to demand another 'technological improvement' rather than 'design improvement.' This cycle of product development may cause both users and producers to disregard the potential of 'display' technology and interface. We must develop a better understanding of significant and unique 'display' potential in comparison with 'real' world communications and current sociological and technological contexts.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2003.10a
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• pp.277-280
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• 2003

It was investigated that the "ㄱ" type angle product could be bended with a curvature during extrusion by extru-bending process. The bending process for the "ㄱ" type angle product can be developed by the hot metal extru-bending machine with the two punches moving in the different velocity. Because of non-symmetry of product, it is important to design the ruled surface contour of dies cavity for the welding and bending with two billets. So it is designed that the multi-hole container has two non-symmetric holes and non-symmetric contour of dies entrance. The results of the experiment show that "ㄱ" type angle product can be bended by the extrusion process and that the curvature of the product can be controlled by the velocity of punch and that the defects such as the distortion of section and the thickness change of the product and the folding and wrinkling of the product did not happen after the bending processing by the extrusion bending machine.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2000.04a
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• pp.83-87
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• 2000

The die for cold forging gets a ver high axial load and radial pressure during processing and hence deforms considerably in the radial direction. This radial deformation of die becomes a important factor influencing the dimensional accuracy of a product. In order to obtain a product with highly accurate dimension therefore it is essential to acquire some information on elastic deformation of the die and the product. The study has been performed for the relation of the deformation between a die and a product in backward extrusion. The strain of the die has been given by the simple experiment using the strain gauges attached to the outer surface of the die. Also the history of the deformation of the die and the product has been given by the experiment and Lames' formula. The results has been compared with the previous another method. The study has given useful results for the deformation history of the die and the product through the experiment and Lame's formula in backward extrusion which can be applied in the die design for the product with accurate dimension

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 1999.03b
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• pp.76-79
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• 1999

The study has been performed for the relation between die and product in forward extrusion by the experiment. Strains of the die have been given by the simple experiment using the strain gauge located at the outer surface of the die and the history of the deformation of the die and product is given by the experiment and Lame's formula. The inner pressure of the die causes the deformation of die that affects the accuracy of dimension and shape of product. The product with accurate dimension and shape can be obtained by analysing elastic deformation of the die during process. The deformation of the die during metal forming process has been usually predicted by the experience of industrial engineer or finite element analysis. But it is difficult to predict the dimension of product at unloading and ejected states. The study has given useful results for the deformation history of the die and product through the experiment and Lame's formula at forward extrusion for solid cylinder and can be applied to the die design for product with accurate dimension.

• International Journal of Advanced Culture Technology
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• v.8 no.3
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• pp.148-158
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• 2020

With the limited product information available in the m-shopping context, product-naming strategies affect consumer choices by expressing the key product features or the brand's images. Given the increasing dominance of the mobile commerce in consumption across various product categories, few studies have examined the role of product naming in consumer choices in the m-shopping. In filling the research gap, this study empirically analyzes the influence of the perceived diagnosticity of product names in m-shopping on consumer attitude towards the product. Moreover, the study tests the moderating influences of the individual characteristics of consumers (i.e., age, gender, and m-shopping experience) in the dynamics of the perceived diagnosticity impacting the product evaluations. The results of the study using an online survey reveal that the perceived diagnosticity of the product names significantly increases consumer attitude towards the product. Additionally, the moderating effects of gender, age, and m-shopping experience are all found significant: (1) The positive influence of the perceived diagnosticity of the product names is greater for males than for females. (2) The older the respondent, the more statistically significant the positive influence on diagnosticity. (3) The more respondents having m-shopping experience, the more positive the impact of the diagnosticity. Implications and limitations of the study are discussed.

• Journal of the Korean Wood Science and Technology
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• v.31 no.2
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• pp.1-15
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• 2003

• International Journal of Oral Biology
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• v.49 no.1
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• pp.10-17
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• 2024

Glutamate-mediated oxidative stress causes neuronal cell death by increasing intracellular Ca²⁺ uptake, reactive oxidative species (ROS) generation, mitogen-activated protein kinase (MAPK) activation, and translocation of apoptosis-inducing factor (AIF) to the nucleus. In the current study, we demonstrated that corydaline exerts potent neuroprotective effects against glutamate-induced neurotoxicity. Treatment with 5 mmol/L glutamate increased cellular Ca²⁺ influx, ROS generation, MAPK activation, and AIF translocation. In contrast, corydaline treatment decreased cellular Ca²⁺ influx and ROS generation. Western blot analysis revealed that glutamate-mediated MAPK activation was attenuated by corydaline treatment. We further demonstrated that corydaline treatment inhibited the glutamate-mediated translocation of AIF to the nucleus. We propose that corydaline is a promising lead structure for the development of safe and effective neuroprotectants.

• Journal of Microbiology and Biotechnology
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• v.29 no.1
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• pp.160-170
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• 2019

The lactic acid bacteria species Lactobacillus plantarum (L. plantarum) has been used extensively for vaccine delivery. Considering to the critical role of dendritic cells in stimulating host immune response, in this study, we constructed a novel CD11c-targeting L. plantarum strain with surface-displayed variable fragments of anti-CD11c, single-chain antibody (scFv-CD11c). The newly designed L. plantarum strain, named 409-aCD11c, could adhere and invade more efficiently to bone marrow-derived DCs (BMDCs) in vitro due to the specific interaction between scFv-CD11c and CD11c located on the surface of BMDCs. After incubation with BMDCs, the 409-aCD11c strain harboring a eukaryotic vector pValac-GFP could lead to more efficient expression of GFP compared with wild-type strains shown by flow cytometry analysis, indicating the enhanced translocation of pValac-GFP from L. plantarum to BMDCs. Similar results were also observed in an in vivo study, which showed that oral administration resulted in efficient expression of GFP in both Peyer's patches (PP) and mesenteric lymph nodes (MLNs) within 7 days after the last administration. In addition, the CD11c-targeting strain significantly promoted the differentiation and maturation of DCs, the differentiation of $IL-4^+$ and $IL-17A^+$ T helper (Th) cells in MLNs, as well as production of $B220^+$ $IgA^+$ B cells in the PP. In conclusion, this study developed a novel DC-targeting L. plantarum strain which could increase the ability to deliver eukaryotic expression plasmid to host cells, indicating a promising approach for vaccine study.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.42 no.1
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• pp.115-128
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• 2019

Small and Medium-sized Enterprises (SMEs) are being faced with rapid changes in their business environments due to evolution of technologies and innovation in societal eco-systems. Particularly, dynamic interactions between such environments and enterprise activities have become significant, so technology planning, which is a process of identifying appropriate directions regarding product and technology development, has received much attention to cope with such dynamics proactively. However, SMEs typically have limits in performing independent, strategical and systematical technology planning activities due to the lack of human, material and financial resources. This paper proposes the development of a product roadmapping method so that SMEs carry out efficient technology planning activities with interconnections of external business environments. The present work provides product roadmap templates that directly accommodate the influence of business environments on the product's system and its associated super/sub-systems with the use of external environment analysis techniques including TRIZ methodology, PEST and 5Forces analysis. These templates are useful to efficiently forecast the directions of product's development and evolution, which arise from changes in external environments. Consequently, the present work enables SMEs to flexibly cope with the era of the next R&D generation, which pursues value creation through mutual interconnection between business environments and technology development.