• Title/Summary/Keyword: Process Life Cycle

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Cell Differentiation and Ultrastructure of the Seminiferous Epithelium in Myotis macrodactylus (큰발웃수염박쥐 (Myotis macrodactylus)의 정상피세포의 분화와 미세구조)

  • Lee, Jung-Hun
    • Applied Microscopy
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    • v.33 no.1
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    • pp.25-39
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    • 2003
  • Cell differentiation and ultrastructural characteristics in the seminiferous epithelium of Myotis macrodactylus was investigated with the light and electron microscopes. Spermatogenesis has begun at April and finished at September. The nuclei of A spermatogonia (dark and pale type of spermatogonia) were oval, applied to the basal lamina, and surrounded by Sertoli cells. By comparison with other types of spermatogonia, the cell and nucleus of B type of spermatogonium is globular and larger than A types of spermatogonia. The nucleolus appears as a coarse and touches the nuclear membrane. The cell and nucleus of spermatocytes was globular and larger, but primary spematocyte is larger than secondary spermatocyte. Spermiogenesis was divided according to the level of fine structural difference, into Golgi, cap, acrosomal, maturation and spermiation phases; Golgi, cap, acrosomal and spermiation phases were further subdivided into steps of early and late phase respectively, and maturation phase has only one step. Hence, the spermiogenesis has been divided into a total of nine phases. In the change of karyoplasm, the chromatin granules are condensed at late Golgi phase and completed at spermiation phase. The sperm tail began to develop in early Golgi phase and completed in spermiation phase. The process of degeneration of spermatogenic cells in the seminiferous tubules was continually observed from October, before the beginning of hibernation, to hibernation phase (November, December, January, February, March). Immatured spermatogenic cells in the seminiferous tubules have been engulfed by phagocytosis of Sertoli cells during period of degeneration. It is deduced that the adaptative strategy serves as the mechanism to regulate the effective use of energy to prepare for long hibernation and regulation of breeding cycle.

Economic Evaluation System for Deteriorated Military Facilities (노후 군시설물의 경제성 평가 시스템)

  • Jang, Won-Suk;Lim, Tae-Kyung;Lee, Dong-Eun
    • Journal of the Korea Institute of Building Construction
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    • v.13 no.2
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    • pp.181-192
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    • 2013
  • Given both structural safety and economic benefits of aging facilities, remodelling of the existing facilities is preferable to reconstruction. This recognition provides an opportunity to reduce the commitment of resources and national budget. However, when a subordinate troop asks for remodeling or reconstruction of a deteriorated facility, it is difficult to ensure the consistency and objectivity in the process of decision making for the alternatives due to the absence of systematic and quantitative rating methodology. Their economic evaluation methodology only exists in a manual format. Thus, further research is required for converting the methodology into an automated system in view of practicality such as rapid and accurate data processing. The contributions of this study are as follows: 1) Literature review found out a representative economic evaluation model focused on military facilities, and comparative analysis with a similar study identified the strength and weakness. 2) this study presented how to convert the theoretical framework which enables to solve a specific subject matter into an automated system. 3) it developed a user friendly interfaces which consist of four functional modules by considering the usability and accessibility of the system user. 4) the developed system was verified by a case study in terms of four kinds of performance indicators.

Analysis of the Gene Expression by Laser Capture Microdissection (III) -Microarray Analysis of the Gene Expression at the Mouse Uterine Luminal Epithelium of the Implantation Sites during Apposition Period- (Laser Capture Microdissection을 이용한 유전자 발현 연구 (III) -생쥐 착상 부위 자궁 내강상피 조직에서 배아 병치 기간 동안 일어나는 유전자 발현에 관한 Microarray 분석-)

  • Yoon, Se-Jin;Jeon, Eun-Hyun;Park, Chang-Eun;Ko, Jung-Jae;Choi, Dong-Hee;Cha, Kwang-Yul;Kim, Se-Nyun;Lee, Kyung-Ah
    • Clinical and Experimental Reproductive Medicine
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    • v.29 no.4
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    • pp.323-335
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    • 2002
  • Object: The present study was accomplished to obtain a gene expression profile of the luminal epithelium during embryo apposition in comparison of implantation (1M) and interimplantation (INTER) sites. Material and Method: The mouse uterine luminal epithelium from IM and INTER sites were sampled on day 4.5 (Day of vaginal plug = day 0.5) by Laser Captured Microdissection (LCM). RNA was extracted from LCM captured epithelium, amplified, labeled and hybridized to microarrays. Results from microarray hybridization were analyzed by Significance Analysis of Microarrays (SAM) method. Differential expression of some genes was confirmed by LCM followed by RT-PCR. Results: Comparison of IM and INTER sites by SAM identified 73 genes most highly ranked at IM, while 13 genes at the INTER sites, within the estimated false discovery rate (FDR) of 0.163. Among 73 genes at IM, 20 were EST/unknown function, and the remain 53 were categorized to the structural, cell cycle, gene/protein expression, immune reaction, invasion, metabolism, oxidative stress, and signal transduction. Of the 24 structural genes, 14 were related especially to extracellular matrix and tissue remodeling. Meanwhile, among 13 genes up-regulated at INTER, 8 genes were EST/unknown function, and the rest 5 were related to metabolism, signal transduction, and gene/protein expression. Among these 58 (53+5) genes with known functions, 13 genes (22.4%) were related with $Ca^{2+}$ for their function. Conclusions: Results of the present study suggest that 1) active tissue remodeling is occurring at the IM sites during embryo apposition, 2) the INTER sites are relatively quiescent than IM sites, and 3) the $Ca^{2+}$ may be a crucial for apposition. Search for human homologue of those genes expressed in the mouse luminal epithelium during apposition will help to understand the implantation process and/or implantation failure in humans.

A Development of 3D Computer-Aided Design(CAD) Add-on Program for a Quantity Take-off through the User Needs Analysis (사용자 요구 사항 분석에 따른 물량산출 연동 프로그램 개발)

  • Kim, Seong-Ah;Lee, Jea-Jun;Shin, Tea-Hong;Chin, Sang-Yoon;Kim, Yea-Sang;Choi, Cheol-Ho
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2008.11a
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    • pp.297-300
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    • 2008
  • Since the Three Dimensional Computer Aided Design(3D CAD) appeared in 1990s, Building Information Modeling(BIM) has got the great issue in the construction project nowadays. BIM is the process of managing and generating building information during life cycle of a construction project. And information can be moved to 3D modeling flexibly in BIM. As a result, a field of estimating has also been doing researches in the calculation of the amount of building materials from 3D modeling. And the Construction Cost Estimating Software which is generally used over the world has been trying to be applied to the Construction project in Korea. But, when we consider the productivity, it is less efficient than the existing way in Korea which use the 2D Drawings when they take off the Quantity. Also, there are lots of difference how to estimate the construction cost. between Korea and the others. Because it is a bit hard to apply the software used in the other countries to the construction project in Korea, people couldn't use it well in the construction project actually. In this study, for developing the appropriate construction cost estimating software rooted in 3D in Korea, we suggest 3D CAD Add-on Program for a Quantity Take-off which can move quantitative information to 3D CAD.

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De Lege Frenda for Improvement of Marine Telemedicine Service System (해양원격의료 지원제도 개선을 위한 관련 법령정비 방안)

  • JEON, Yeong-Woo;HONG, Sung-Hwa;KIM, Jae-Ho
    • Journal of Fisheries and Marine Sciences Education
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    • v.28 no.4
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    • pp.994-1005
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    • 2016
  • Expansion and spreading of marine telemedicine is rather restricted due to the conflict of laws relating to medical service and lack of provisions in the Seafarers' Act, Medical Service Act, etc. Thus, this study is intended to reveal the current status and problems of marine emergency medical advice system for the furtherance of health care of seafarers and emergency medical assistance conditions and deduce relevant proposals for legislative improvements thereof in order to resolve underlying problems and issues. The results of this study can be summated as follows. First, in respect of directions to provide marine emergency service based on marine telemedicine system, emergency radio medical advice system needs to be strengthened to meet domestic and international instrument, marine telemedicine system needs to be provided through integrating u-Health technology and special marine medical center needs to be established. Second, regarding directions to provide health promotion service based on the marine telemedicine system, a new process of health care service for seafarers needs to be devised and provided involving seafarers' life cycle covering from prior to boarding to after leaving a ship. The conclusions of this study can be given as follows. First, the following new provisions need to be introduced in the Seafarers' Act. (1) The Minister of Oceans and Fisheries and a shipowner shall conduct matters pertaining to preventive health promotion and care for seafarers; (2) a provisions regarding establishment of seafarers' health promotion center by the Minister; (3) a special exemption permitting marine telemedicine service and qualification requirements for marine telemedicine assistant; (4) shipowner's obligation of carrying seafarers' health measuring equipment on board. Second, the relevant provisions regarding medical care persons needs to be revised in such a way that master or chief officer shall be appointed to be in charge of medical care on board. Last but not least, it is also essential to amend and update the minimum standards on drug and medicines to be carried on board and medicine chest and equipment on board.

Priority Analysis of Project Stage-wise Risk Factors : Focusing on New Product Development Projects in ICT Industry (프로젝트 단계별 리스크 요인들의 우선순위 분석 : ICT(정보통신기술)산업 분야의 신제품 개발 프로젝트를 중심으로)

  • Jang, Heeseok;Choi, Sungyong;Lee, Minho
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.41 no.3
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    • pp.72-82
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    • 2018
  • In this paper, we identify risk factors that are likely to occur during the lifecycle of a new product development (NPD) project from the literatures, and identify the three objectives or three constraints that will ultimately be achieved for project success in the ICT industry : performance (scope/quality), schedule (time), and cost. Firstly, we interviewed the project experts to classify the risk factors according that the final project objectives are changeable based on scope/quality, time and cost budget constraints. Secondly, the survey for pairwise comparisons between the risk factors was asked to the project managers and members who had ever actually participated in the NPD projects of ICT industry to determine the priority ranks on relative importance using AHP (Analytic Hierarchy Process). The risk factors negatively affecting the goals of projects were analyzed by using the AHP respectively in four project stages during the life cycle of the project. The comparison of risk factors within each stage is a different approach unlike the literatures which have covered project's overall risk assessment. There is an advantage that risk management can be effectively performed with priorities according to each stage from the start to the end of the project. In other words, it is necessary to identify what risk factors will occur in each stage, and to have ideas at each stage with the priorities so that they can be mitigated and eliminated before actual occurrence. As a result, risks on scope & quality changes were found to be the most important considerations for initiative stage of NPD projects in the ICT industry, whereas in the final stage, risks on schedule (time) changes were the most important priorities. Among the ICT industry product categories, 'communication and broadcasting devices' and 'IT and communication based devices' generally have a high priority in terms of risks on scope & quality changes when initiating the project. At the closing stage of the project, however, considering that schedule (time) changeable risk is getting higher, these products tend to target at B2B market rather than B2C because the new products must be delivered and launched in time as customer firm required.

Electrochemical Characteristics of Ru Added Li4Ti5O12 as an Anode Material (Ru를 첨가한 음극활물질 Li4Ti5O12의 전기화학적 특성)

  • Cho, Woo-Ram;Na, Byung-Ki
    • Clean Technology
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    • v.20 no.4
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    • pp.433-438
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    • 2014
  • There is an increasing interest in the development of rechargeable batteries suitable for use in both hybrid electric vehicles and energy storage systems that require higher charge & discharge rates, bigger battery sizes and increased safety of the batteries. Spinel-type lithium titanium oxide ($Li_4Ti_5O_{12}$) as a potential anode for lithium ion batteries has many advantages. It is a zero-strain materials and it experiences no structural change during the charge/discharge precess. Thus, it has long cycle life due to its structural integrity. It also offers a stable operation voltage of approximately 1.55 V versus $Li^+/Li$, above the reduction potential of most organic electrolyte. In this study, Ru added $Li_4Ti_5O_{12}$ composites were synthesized by solid state process. The characteristics of active material were investigated with TGA-DTA, XRD, SEM and charge/discharge test. The capacity was reduced when Ru was added, however, the polarization decreased. The capacity rate of $Li_4Ti_5O_{12}$ with Ru (3%, 4%) addition was reduced during the charge/discharge precess with 10 C-rate as a high current density.

Caring Experience of Mothers with IDDM Children (인슐린의존형 당뇨병 환아 어머니의 돌봄 경험)

  • 최미혜
    • Journal of Korean Academy of Nursing
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    • v.28 no.1
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    • pp.81-92
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    • 1998
  • This study is to define the caring experience of mothers with insulin-dependent diabetes mellitus children, by finding core category, contextual factors, ntervening factors, and the patterns of caring, and to velop a practice theory on it. Research method followed grounded theory methodology by Strauss & Corbin. Subjects were six mothers. whose children have had insulin-dependent diabetes mellitus for 4 months to 14 years by the interview time. They were selected by theoretical sampling. Data were collected from September, 1995 to January, 1996. Interview were done by long interview technique and observation. Each interview took 50 minutes to 2 hours. Content of interview was recorded and transcribed later. Based on the results of previous interview, content of next interview was planned until data reached to the saturation point. Results were as follows : One hundred and forty concepts were found. These concepts were grouped into thirty-three categories, and then to ten categories. Mothers with diabetic child were revealed to face “being overwhelmed by burden”. Overwhelming by burden is found to be progressed through the cycle production-coping-decrease or in crease process. Mothers showed four patterns of adaptation in caring the diabetic children. 1) If mothers felt large amount of overwhelming by burden because of difficulty of caring and unsympathizing but they had sufficient support, no condition of the child, and their coping mechanism was positive, most of them overcome with strong will, but some fell into burnout. 2) If mothers felt large amount of overwhelming by burden because of difficulty of caring, unsympathizing, insufficient support. serious condition of the child, and their coping mechanism was negative, they fell into burnout by coping with feeling. 3) If mothers felt small amount of overwhelming by burden because of little difficulty of caring and sympathizing, sufficient support. no serious condition of the child, but their coping was negative, most of them fell into burnout by coping with feeling, but some overcome. 4) If mothers felt small amount of overwhelming by burden because of little difficulty of caring and unsympathizing, sufficient support, no serious condition of the child, and their coping was positive, they overcome with strong will. On the basis of the above result, in order to help mothers take good care of their children, nursing assesment and intervention on life readjustment, and getting support should be required. Especially, through understanding mothers' personalities, individual support consistent with each of them should be required. Therefore education. counseling, mutual support and exchange of information will have to be accomplished.

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Selection of Integrated Concepts Across Science and Humanities Using the Delphi Method (과학과 인문학의 통합개념 선정을 위한 델파이 연구)

  • Kim, Jiyoung;Park, Jieun;Yoon, Heojeong;Park, Eunmi;Bang, Dami
    • Journal of The Korean Association For Science Education
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    • v.34 no.6
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    • pp.549-558
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    • 2014
  • Integrated concepts that are broad enough to embrace facts, principles, laws, and concepts of multiple disciplines could become the core of integrated education. Integrated concept-centered education enables effective and practical learning. In this study, the Delphi Method was implemented targeting experts in science (physics, life science, chemistry, and earth science) and humanities (history, geology, economics, ethics, and politics) to find out the integrated concept that can be used to design the concept-centered integrated education in the Republic of Korea. 124 experts participated in this survey. Delphi survey was conducted for three rounds. In the first round, an open questionnaire was given to experts to collect feasible integrated concepts in each major field. Then, in the second round experts were asked to select integrated concepts that could be used practically in the field of their major. In the third round, the integrated concept with selection frequency over medium value were given. They were asked to evaluate the applicability of integrated concepts by using the Likert-scale questionnaire. Through this process, content validity was analyzed. As a result, five integrated concepts (change, interaction, space-time, energy, and equilibrium) were selected for the inter-science integration. And thirteen integrated concepts (conflict, community, relationship, structure, power, diversity, culture, change, society, interaction, freedom, justice, and equality) were chosen for the inter-humanities integration. Finally, for the science-humanities integration, seven integrated concepts (structure, diversity, change, interaction, cycle, system, and environment) were determined.

The Establishment of Service Cloud Based Expansion and Developing Plan for National Spatial Data Infrastructure (서비스 클라우드 기반 국가공간정보통합체계 확대발전방안 수립)

  • Youn, Junhee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.1
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    • pp.367-373
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    • 2016
  • The construction of National Spatial Data Infrastructure (NSDI) started from 2008 and was completed at 2012, with the aim of co-utilizing public agencies' national spatial information by integrating and linking. Despite the existence of the NSDI, an update of spatial data is not fully reflected because the spatial information has not been updated simultaneously by NSDI and public agencies. By examining the public agencies' services using the spatial information, a national budget is wasted because the re-usable similar services are duplicated. These issues could be solved by adopting a cloud system, whose concept is co-utilizing IT resources, to the NSDI. This study examined the service cloud based expansion and development plan for NSDI. The plan included an implementation strategy for a spatial information service cloud system and an establishment plan for a governance system. The service scenarios, concept diagram, and service functions for the system were derived in a system implementation plan. For the service functions, the unit functions of two modules were proposed and specific functions were derived. In the establishment of a governance system, the business roles and business processes were defined for organizations managing service cloud based NSDI. The business role and process were defined and derived by each service life-cycle step. With the proposed system implementation plan, a detail system design and composition of the organization could be possible, and a service cloud-based NSDI system could be implemented.