• Title/Summary/Keyword: Probability and statistics

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Medication Errors in Chemotherapy Preparation and Administration: a Survey Conducted among Oncology Nurses in Turkey

  • Ulas, Arife;Silay, Kamile;Akinci, Sema;Dede, Didem Sener;Akinci, Muhammed Bulent;Sendur, Mehmet Ali Nahit;Cubukcu, Erdem;Coskun, Hasan Senol;Degirmenci, Mustafa;Utkan, Gungor;Ozdemir, Nuriye;Isikdogan, Abdurrahman;Buyukcelik, Abdullah;Inanc, Mevlude;Bilici, Ahmet;Odabasi, Hatice;Cihan, Sener;Avci, Nilufer;Yalcin, Bulent
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권5호
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    • pp.1699-1705
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    • 2015
  • Background: Medication errors in oncology may cause severe clinical problems due to low therapeutic indices and high toxicity of chemotherapeutic agents. We aimed to investigate unintentional medication errors and underlying factors during chemotherapy preparation and administration based on a systematic survey conducted to reflect oncology nurses experience. Materials and Methods: This study was conducted in 18 adult chemotherapy units with volunteer participation of 206 nurses. A survey developed by primary investigators and medication errors (MAEs) defined preventable errors during prescription of medication, ordering, preparation or administration. The survey consisted of 4 parts: demographic features of nurses; workload of chemotherapy units; errors and their estimated monthly number during chemotherapy preparation and administration; and evaluation of the possible factors responsible from ME. The survey was conducted by face to face interview and data analyses were performed with descriptive statistics. Chi-square or Fisher exact tests were used for a comparative analysis of categorical data. Results: Some 83.4% of the 210 nurses reported one or more than one error during chemotherapy preparation and administration. Prescribing or ordering wrong doses by physicians (65.7%) and noncompliance with administration sequences during chemotherapy administration (50.5%) were the most common errors. The most common estimated average monthly error was not following the administration sequence of the chemotherapeutic agents (4.1 times/month, range 1-20). The most important underlying reasons for medication errors were heavy workload (49.7%) and insufficient number of staff (36.5%). Conclusions: Our findings suggest that the probability of medication error is very high during chemotherapy preparation and administration, the most common involving prescribing and ordering errors. Further studies must address the strategies to minimize medication error in chemotherapy receiving patients, determine sufficient protective measures and establishing multistep control mechanisms.

Water Quality Assessment and Turbidity Prediction Using Multivariate Statistical Techniques: A Case Study of the Cheurfa Dam in Northwestern Algeria

  • ADDOUCHE, Amina;RIGHI, Ali;HAMRI, Mehdi Mohamed;BENGHAREZ, Zohra;ZIZI, Zahia
    • 공업화학
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    • 제33권6호
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    • pp.563-573
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    • 2022
  • This work aimed to develop a new equation for turbidity (Turb) simulation and prediction using statistical methods based on principal component analysis (PCA) and multiple linear regression (MLR). For this purpose, water samples were collected monthly over a five year period from Cheurfa dam, an important reservoir in Northwestern Algeria, and analyzed for 12 parameters, including temperature (T°), pH, electrical conductivity (EC), turbidity (Turb), dissolved oxygen (DO), ammonium (NH4+), nitrate (NO3-), nitrite (NO2-), phosphate (PO43-), total suspended solids (TSS), biochemical oxygen demand (BOD5) and chemical oxygen demand (COD). The results revealed a strong mineralization of the water and low dissolved oxygen (DO) content during the summer period. High levels of TSS and Turb were recorded during rainy periods. In addition, water was charged with phosphate (PO43-) in the whole period of study. The PCA results revealed ten factors, three of which were significant (eigenvalues >1) and explained 75.5% of the total variance. The F1 and F2 factors explained 36.5% and 26.7% of the total variance, respectively and indicated anthropogenic pollution of domestic agricultural and industrial origin. The MLR turbidity simulation model exhibited a high coefficient of determination (R2 = 92.20%), indicating that 92.20% of the data variability can be explained by the model. TSS, DO, EC, NO3-, NO2-, and COD were the most significant contributing parameters (p values << 0.05) in turbidity prediction. The present study can help with decision-making on the management and monitoring of the water quality of the dam, which is the primary source of drinking water in this region.

Imaging of Facial Nerve With 3D-DESS-WE-MRI Before Parotidectomy: Impact on Surgical Outcomes

  • Han-Sin Jeong;Yikyung Kim;Hyung-Jin Kim;Hak Jung, Kim;Eun-hye Kim;Sook-young Woo;Man Ki Chung;Young-Ik Son
    • Korean Journal of Radiology
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    • 제24권9호
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    • pp.860-870
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    • 2023
  • Objective: The intra-parotid facial nerve (FN) can be visualized using three-dimensional double-echo steady-state water-excitation sequence magnetic resonance imaging (3D-DESS-WE-MRI). However, the clinical impact of FN imaging using 3D-DESS-WE-MRI before parotidectomy has not yet been explored. We compared the clinical outcomes of parotidectomy in patients with and without preoperative 3D-DESS-WE-MRI. Materials and Methods: This prospective, non-randomized, single-institution study included 296 adult patients who underwent parotidectomy for parotid tumors, excluding superficial and mobile tumors. Preoperative evaluation with 3D-DESS-WE-MRI was performed in 122 patients, and not performed in 174 patients. FN visibility and tumor location relative to FN on 3D-DESS-WE-MRI were evaluated in 120 patients. Rates of FN palsy (FNP) and operation times were compared between patients with and without 3D-DESS-WE-MRI; propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) were used to adjust for surgical and tumor factors. Results: The main trunk, temporofacial branch, and cervicofacial branch of the intra-parotid FN were identified using 3D-DESS-WE-MRI in approximately 97.5% (117/120), 44.2% (53/120), and 25.0% (30/120) of cases, respectively. The tumor location relative to FN, as assessed on magnetic resonance imaging, concurred with surgical findings in 90.8% (109/120) of cases. Rates of temporary and permanent FNP did not vary between patients with and without 3D-DESS-WE-MRI according to PSM (odds ratio, 2.29 [95% confidence interval {CI} 0.64-8.25] and 2.02 [95% CI: 0.32-12.90], respectively) and IPTW (odds ratio, 1.76 [95% CI: 0.19-16.75] and 1.94 [95% CI: 0.20-18.49], respectively). Conversely, operation time for surgical identification of FN was significantly shorter with 3D-DESS-WE-MRI (median, 25 vs. 35 min for PSM and 25 vs. 30 min for IPTW, P < 0.001). Conclusion: Preoperative FN imaging with 3D-DESS-WE-MRI facilitated anatomical identification of FN and its relationship to the tumor during parotidectomy. This modality reduced operation time for FN identification, but did not significantly affect postoperative FNP rates.

고소작업 사고 시나리오 기반 웨어러블 응용 HSE 시스템 안전관리 방안 (HSE System Safety Management Using Wearable Based on Accident Scenario of High Place Work)

  • 조윤정;임기창;임동선;박정호;김종면
    • 예술인문사회 융합 멀티미디어 논문지
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    • 제8권5호
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    • pp.417-425
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    • 2018
  • 본 논문에서는 조선해양 작업장에서 발생하는 중대재해를 줄이고 체계적인 안전관리를 위하여 ETA(event tree analysis)기반 시나리오 도출 및 ICT 기술접목을 통한 안전관리 구축방안을 제안한다. 안전보건공단과 (구)국민안전처의 통계결과 조선해양 관련 중대재해 중 가장 많이 발생하는 사고유형은 떨어짐이고, 주요사고원인은 안전대 미착용 및 안전대 고리 미체결이다. 이 문제를 해결하기 위해 ETA기반의 시나리오를 작성하여 안전사항에 따른 결과를 도출하고 이 결과를 바탕으로 사고예방을 위한 ICT 기술접목으로 해결방안을 제시한다. ETA 기반 시나리오 도출 및 ICT 기술접목을 통해 제안한 해결방안으로는 안전대 및 안전모 착용여부 감지시스템, 안전대 고리 체결여부 감지시스템, 안전거리 측정을 위한 걸이설비 측정시스템이다. 안전사항별 시스템을 통해 작업자의 떨어짐 위험을 줄여 사망확률을 낮출 수 있다. 제안한 방안을 통해 사고를 예방함으로써 조선해양 분야의 중대재해를 줄이고 체계적인 안전관리를 도모한다.

설계강우량 산정을 위한 매개변수 추정방법 평가 (Evaluation of Parameter Estimation Method for Design Rainfall Estimation)

  • 김귀훈;전상민;장정렬;송인홍;강문성;최진용
    • 한국농공학회논문집
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    • 제63권4호
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    • pp.87-96
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    • 2021
  • Determining design rainfall is the first step to plan an agricultural drainage facility. The objective of this study is to evaluate whether the current method for parameter estimation is reasonable for computing the design rainfall. The current Gumbel-Kendall (G-K) method was compared with two other methods which are Gumbel-Chow (G-C) method and Probability weighted moment (PWM). Hourly rainfall data were acquired from the 60 ASOS (Automated Synoptic Observing System) stations across the nation. For the goodness-of-fit test, this study used chi-squared (𝛘2) and Kolmogorov-Smirnov (K-S) test. When using G-K method, 𝛘2 statistics of 18 stations exceeded the critical value (𝑥2a=0.05,df=4=9.4877) and 10, 3 stations for G-C method, PWM method respectively. For K-S test, none of the stations exceeded the critical value (Da=0.05n=0.19838). However, G-K method showed the worst performances in both tests compared to other methods. Subsequently, this study computed design rainfall of 48-hour duration in 60 ASOS stations. G-K method showed 5.6 and 6.4% higher average design rainfall and 15.2 and 24.6% higher variance compared to G-C and PWM methods. In short, G-K showed the worst performance in goodness-of-fit tests and showed higher design rainfall with the least robustness. Likewise, considering the basic assumptions of the design rainfall estimation, G-K is not an appropriate method for the practical use. This study can be referenced and helpful when revising the agricultural drainage standards.

제3기 퇴적암 및 화산암 분포지의 산사태 예측모델 (A Prediction Model of Landslides in the Tertiary Sedimentary Rocks and Volcanic Rocks Area)

  • 채병곤;김원영;나종화;조용찬;김경수;이춘오
    • 지질공학
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    • 제14권4호
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    • pp.443-450
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    • 2004
  • 이 연구는 제3기 퇴적암과 화산암이 분포하는 지역의 자연사면에서 발생하는 토석류 산사태를 예측하고자 로지스틱 회귀분석(logistic regression analysis)을 이용하여 예측모델을 개발한 것이다. 통계적 방법을 이용한 산사태 예측모델 개발을 위해 산사태 자료는 경북 포항지역에서 1998년 발생한 산사태를 대상으로 수집하였다. 로지스틱 회귀분석의 기본 특성을 고려하여 현장조사 및 실내토질시험은 산사태 발생지점 전체와 임의로 선택한 미발생 지점을 대상으로 실시하였다. 산사태 발생에 영향을 미치는 인자는 로지스틱 회귀분석을 실시하여 최종적으로 6개 영향인자를 선정하였다. 이들 6개 인자는 지형요소 2개와 지질요소 4개로 구성되어 있다. 개발된 모델은 신뢰성 검증을 수행한 결과 $90\%$ 이상의 예측률을 확보한 것으로 나타났다. 이 모델을 바탕으로 기존에 제시된 변성암 및 화강암 분포지에서의 산사태 예측모델과 함께 지질특성을 고려한 산사태 발생의 가능성을 확률적${\cdot}$정량적으로 예측할 수 있게 되었다.

ICT 인프라 이상탐지를 위한 조건부 멀티모달 오토인코더에 관한 연구 (A Study of Anomaly Detection for ICT Infrastructure using Conditional Multimodal Autoencoder)

  • 신병진;이종훈;한상진;박충식
    • 지능정보연구
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    • 제27권3호
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    • pp.57-73
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    • 2021
  • ICT 인프라의 이상탐지를 통한 유지보수와 장애 예방이 중요해지고 있다. 장애 예방을 위해서 이상탐지에 대한 관심이 높아지고 있으며, 지금까지의 다양한 이상탐지 기법 중 최근 연구들에서는 딥러닝을 활용하고 있으며 오토인코더를 활용한 모델을 제안하고 있다. 이는 오토인코더가 다차원 다변량에 대해서도 효과적으로 처리가 가능하다는 것이다. 한편 학습 시에는 많은 컴퓨터 자원이 소모되지만 추론과정에서는 연산을 빠르게 수행할 수 있어 실시간 스트리밍 서비스가 가능하다. 본 연구에서는 기존 연구들과 달리 오토인코더에 2가지 요소를 가미하여 이상탐지의 성능을 높이고자 하였다. 먼저 다차원 데이터가 가지고 있는 속성별 특징을 최대한 부각하여 활용하기 위해 멀티모달 개념을 적용한 멀티모달 오토인코더를 적용하였다. CPU, Memory, network 등 서로 연관이 있는 지표들을 묶어 5개의 모달로 구성하여 학습 성능을 높이고자 하였다. 또한, 시계열 데이터의 특징을 데이터의 차원을 늘리지 않고 효과적으로 학습하기 위하여 조건부 오토인코더(conditional autoencoder) 구조를 활용하는 조건부 멀티모달 오토인코더(Conditional Multimodal Autoencoder, CMAE)를 제안하였다. 제안한 CAME 모델은 비교 실험을 통해 검증했으며, 기존 연구들에서 많이 활용된 오토인코더와 비교하여 AUC, Accuracy, Precision, Recall, F1-score의 성능 평가를 진행한 결과 유니모달 오토인코더(UAE)와 멀티모달 오토인코더(Multimodal Autoencoder, MAE)의 성능을 상회하는 결과를 얻어 이상탐지에 있어 효과적이라는 것을 확인하였다.

남녀청소년의 다양한 스트레스(부모, 학업, 친구, 외모, 경제), 학교생활적응과 행복감의 관계성 연구: 매개관계를 중심으로 (A Relationship Study of Adolescents' Various Stress, School-life Adjustment, and Happiness: mediating effects)

  • 김선아
    • 한국산학기술학회논문지
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    • 제21권9호
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    • pp.161-169
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    • 2020
  • 본 연구는 남녀 청소년의 다양한 스트레스와 학교생활적응이 행복감에 미치는 영향과 관계성에 대해서 살펴보고 청소년들의 행복감을 향상시키는 방안의 기초자료로 활용하고자 한다. 연구대상은 '한국 어린이·청소년 행복지수 2018년도 조사' 중고등학교 자료 5,144명을 활용했고, 2017년 교육기본통계자료를 기반으로 학급을 표집단위로 크기비례확률 추출법을 활용하여 표집했다. 구조방정식과 다중집단분석을 통한 연구결과로, 첫째, 청소년들의 행복감에는 학업스트레스, 친구스트레스, 외모스트레스가 부적으로 유의미한 영향을 주는 것으로 나타났다. 학교생활적응도 행복감과 정적으로 유의미한 관계였고 각 스트레스와 학교생활적응의 관계에서는 부모스트레스, 경제스트레스와 학업스트레스가 유의미하게 나타났다. 둘째, 각 스트레스와 행복감에서 학교생활적응의 매개효과는 부모스트레스, 학업스트레스와 경제적 스트레스만 학교생활적응을 통해 유의미한 간접효과가 있는 것으로 나타났다. 셋째, 각 스트레스와 행복감의 관계에서 남녀차이에 대한 다중집단 구조분석 결과, 두 집단구조가 비슷한 것으로 나타났다. 남녀집단의 매개효과 결과에서는 차이가 있었는데, 남학생은 학업스트레스와 경제스트레스만 유의미한 매개효과가 나타났고, 여학생은 학업, 경제와 부모스트레스가 학교생활적응을 통한 유의미한 매개효과가 있었다. 연구결과에 따른 청소년들의 행복감에 대한 개입과 실천적 함의에 대한 제안과 과제가 제시되었다.

농촌지역 주민의 건강관련 행위와 질병이환과의 관계 (Health related practices and morbidity among adult in rural area)

  • 송주복;이부옥;신해림;정갑열;김준연
    • Journal of Preventive Medicine and Public Health
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    • 제30권2호
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    • pp.342-355
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    • 1997
  • This research was carried out to determine the performance rate of health related practices, to measure the agreement between morbidity by doctor's diagnosis and morbidity by subject' self-reported and the degree of association between health related practices and morbidity rate by doctor's diagnosis, to identify their effects on morbidity among rural area populations. The data were gathered by volunteer residents (over the age of 20) of Haman Myeon, Haman Gun, Kyeongsangnam Do in Korea, from June 10, 1993 to June 12, 1993 (369 male and 516 female). Face to face interview, lab, chest P-A, EKG and physical examination were completed. Descriptive statistics, agreement analysis and multiple logistic regression procedures were employed for analyses. The results of the study were summarized as follows : 1) Age adjusted morbidity rates by doctor's diagnosis and self-reported were 38.5% (male:37.3%, female:36.5%), 26.4% (male:33.3%, female:27.5%), respectively. Kappa coefficient between morbidity by doctor's diagnosis and morbidity by self-reported was 0.21 (male:0.21, female:0.22). 2) The frequency of disease by doctor's diagnosis was as follows: hypertension(15.3%), gastritis (9.6%), diabetes mellitus (8.5%), live. disease (8.1%), and degenerative arthritis (6.2%) in the study population. 3) Order of health practice performance rate was as follows: Males-normal body weight (62.1%), non-heavy alcohol consumption (57.5%), 7-8 hours of sleeping (50.1%), non-smoking (21.7%), and exercise (19.8%). Females- non-heavy alcohol consumption (97.3%), non-smoking (84.7%), normal body weight (57.8%), 7-8 hours of sleeping (45.0%), and exercise (9.9%). 4) There was no significant relationship between health related practice and morbidity except exercise among health related practices. 5) Health related practice index which was recategorized by high, medium, and low had effects on the probability of developing morbidity.

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성역할 태도와 맞벌이 태도의 차이에 관한 연구: 기혼·유자녀 가구를 중심으로 한 유형화 (A Study on the Difference between Gender Role Attitude and Dual Income Attitude: Focusing on Classification of Married Couple with Children)

  • 정윤태;서재욱
    • 한국가족관계학회지
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    • 제21권1호
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    • pp.143-160
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    • 2016
  • Objectives: The purpose of this study is to empirically verify the difference between traditional gender role attitude and realistic dual earner attitude. Most preceding studies analyzed gender role attitude by summated rating scale while few studies have been conducted on the difference between traditional gender role attitude and dual earner attitude. Method: By using the 9th Korea Welfare Panel Data (year 2014), this study extracted households of married couples and with children in working age (18 through 64 years of age) who are the main subjects in work-family relationship. First, this study classified traditional group and modern group in their gender role attitude and passive group and active group in their dual earner attitude and by crossing these attitudes, drew out 4 gender role/dual earner attitudes. For analysis, this study investigated frequency of attitude types through descriptive statistics. By conducting ANOVA, study verified if there are significant differences in the satisfaction with family relationship depending on the types of gender role/dual earner attitudes. Lastly, study examined the effect of socio-economic status and demographic characteristics on the types of gender role/dual earner attitudes by conducting multi-nominal logistic regression analysis. Results: As the result of analysis, first, half of respondents belonged to 'equal-role-oriented type' who has modern gender role attitude and active dual earner attitude. However, there were not a few 'dual-earner-avoiding type' who has modern gender role attitude but passive dual earner attitude and 'incongruous attitude type' who has traditional gender role attitude but active dual earner attitude. Next, 'incongruous attitude type' had significantly low level of satisfaction with overall family life, relationship with spouse and relationship with children than other attitude types. Lastly, those whose incomes belong to poor strata, those who are high school graduates and lower, males and those who are over the age of 60 had significantly higher probability of belonging to 'incongruous attitude type.' Conclusion: The results of analysis demonstrate that the difference between gender role attitude and dual earner attitude is an important matter and since 'incongruous attitude type' exhibits low level of satisfaction with family relationship, scrupulous policy approaches are required for those who have high possibility of belonging to 'incongruous attitude type.'