This paper examines the American Civil Liberties Union(ACLU)'s recent legal challenge on patents held by Myriad Genetics on two genes (BRCA1 and BRCA2) associated with a high risk of breast and ovarian cancer. Instead of analyzing the ACLU's objections to the BRCA patents in terms of its legal technicalities and normative ethical principles, this paper seeks to situate this legal case in the broader historical context of the shifting understanding of the relationship between private ownership, economic development, and the public interest in academic sciences. This paper first briefly chronicles a series of scientific developments and key legal decisions involving patenting of life forms, including genetically engineered micro-organisms animals and biological materials of human origins like cell cultures and genes, that led to the US Patent and Trademark Office(USPTO)'s official guidelines on human gene patenting in 2001. At another level, this paper analyzes the expansion of the scope of intellectual property rights in the life sciences in terms of shifting economic and legal assumptions about public knowledge and its role for economic development in the 1970s. I then show how these economic, legal, and ethical ideas that linked private ownership and the public interest have been challenged from the 1990s, calling for revisions in intellectual property laws regarding a wide array of life forms. The tragedy of the anticommons in human gene patenting, according to ACLU, has severely undermined creative scientific activities, medical innovations, access to health care and rights to life among cancer patient groups. ACLU's objection to human gene patenting on several US-constitutional grounds in turn suggests issues regarding intellectual property are critically linked to vital issues pertinent to the creative communities in arts and sciences, such as free exchange of ideas, censorship and monopoly, and free expression and piracy etc.
The Journal of the Convergence on Culture Technology
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v.9
no.3
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pp.461-470
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2023
This paper analyzes the spatial representations constructed by reality, filming, and narrative in the works of Hong Kong film director Wong Kar-wai, and how these spaces influence Hong Kong's urban culture, perception, and interpersonal relationships. To analyze Wong Kar-wai's films, Charles Sanders Peirce's semiotics concepts and Paul Virilio's spatial concepts were applied. Through this, we examined how the meaning embedded in the spatial representations of Wong Kar-wai's films could become a crucial factor in their success. Wong Kar-wai focused on the values of human relationships formed by society in his subject expression, directly representing the human inner world and prompting audiences to think about it. In this paper, we categorized the spaces depicted in Wong Kar-wai's films as public, private, and connective spaces, and analyzed them as a means to show the living environment and emotions of Hong Kong's youth. Through this, we determined that the spatial representations in Wong Kar-wai's films effectively demonstrate the cultural interpretation function of Hong Kong's citizen consciousness at the junction of Eastern and Western cultures and social connections. In conclusion, Wong Kar-wai's works provide a rich understanding of contemporary people's lives, emotions, and urban spaces, offering valuable insights into Hong Kong's film industry and cultural values.
In the current so-called age of emotion marketing, the independent form of handwriting of calligraphy is being revitalized in various fields such as advertising, book designs, film titles, posters, packages, BI, and even fashion. Thus centered on Gyeyang-gu at the city of Incheon, 100 outdoors signs that used calligraphy were chosen and we researched a reform plan that could revitalize calligraphy in outdoor signs by classifying them according to current conditions of the use of calligraphy, actual conditions of practical use, expression tools, and analyzing the use of colors. The result was trial requests not only from the formalities industry, but also the financial sector, public corporations, and several other businesses, but in order to provide not only for franchise brand logotypes manufactured by expensive experts, but also provide production of high-quality calligraphy for low costs for small private enterprises, the development of a diverse calligraphy education program, centered on the regional society, will be needed. In the midst of globalization, in order to advertise the beauty of Korean alphabet and to create our own unique street culture, a variety of tools and tactile expressions are demanded, in the future the research on the calligraphy of outdoor signs must be revitalized.
Purpose: The aim of the study was to develop the Korean version of the Working Alliance Inventory (KWAI) and to assess reproducibility of both its therapist and client forms. Methods: The 12-item WAI was translated into Korean. The translation procedure followed the guidelines proposed by Beaton et al. (2000). Development of KWAI involved its translation, back-translation, and pilot testing of the pre-final version to establish Korean cultural adaptation of the original version of WAI. For test-retest reliability, therapists (N=30) and clients (N=47) completed the questionnaire on two different occasions. The interval between occasions was two to seven days, depending on subject availability. Data were collected from clinicians working in general hospitals and private clinics, and clients who had received treatment within three months. The intra-class correlation (ICC ($_{2.1}$)) was calculated for assessment of the reproducibility of the translated questionnaire. Results: The test-retest ICC ($_{2.1}$) of the client form and the therapist form was 0.92 (95%CI:0.86-0.95) and 0.94 (95%CI:0.89-0.97), respectively. Answers to items 2, 8, and 11 showed a tendency to be omitted due to ambiguity of meaning in Korean. Idiomatic expression was employed rather than word-to-word translation to have clear meaning of those items. Conclusion: The KWAI was successfully translated and adapted for applications to Korean clients and therapists, with a satisfactory level of reliability. Therefore, it can be suggested that the KWAI is useful in providing a reliable assessment of working alliance between therapists and clients.
Recently the fashion design has been expressed mixing trend of antipodal concept. There are shown disorganization of existing standard with eclectism, pursued more sensational fashion by the sense of unease. And there are spreaded body exposure in producing on a commercial scale for sex, are shown the phenomenon by wearing innovation inner-wear in private area are exposed out. The purpose of this study are to consider preponderantly the fashion design using corset, shown up as the motive of costume design from 1990's to 2002's, define the character of molding. and extend the width of understanding of modern fashion. The results of the study are as follows: 1. The trend of deconstructionism as one line of fashion world in the 1990's make into outer garment of inner-wear, corset has been using the main item of infra costume. The past corset was existed innerwear, but it is revived various forms by transforming outer garment of body expression consciously. 2. Corset look is shown double faced factory of the beauty of tradition and decadence, vulgarity and nobility, concealment and exposure, and are expressed boldly the free consciousness outer about woman's sex with the improvement of woman's social position. 3. The molding character of Corset look divided Eroticism, Fetishism, Deconstructionism. Futurism. The trend of Corset look design is the emphasized sexual part of lace-up and cutting line of corset, and various details of see-through, kitsch, glitter look. Therefore, the trend of Corset look will be applied the modern fashion and used as motif of new design, affected the inspiration of more developed design with grafting of up-to-date fabrics and processing technique.
In order to satisfy the high expectations of consumers for a variety of consumer's desired subject area, information could be provided in the form of a map according to the analysis information. With the name change in 2015, LX would intend to play a role in building the information infrastructure that can be supported government policy as an intermediary between the government and private sector. Therefore, in this study, we would like to propose a plan that provide personalized information to the consumer. Through compositing a variety of time-series data(inner or outer of LX) based on public information, and analyzing spatially and temporally the rapidly changing land status. For these purpose, prior research and domestic or abroad thematic map service about thematic map making were reviewed. And the reason why the LX makes information map was presented. Also, themes of 3 field were selected, and depending on the data processing or analysis level and theme were subdivided, and then production and expression method were proposed.
Focusing on the cases applied to korean brand-name apartments In 1960s, economical growth and introduction of western-type cultures led to a boom of apartment construction. After internationalization'in 1980s through Olympic games in 1988, korean culture has attracted attention and individual life quality has been improved. Since 1990s, changes in personal life style has affected the housing culture and the construction companies started moving from quantitative supply to developing their own differential characteristics. Differentiation scheme triggered by construction companies since mid-1990s mainly focused on various ideas for space deployment. Space plans include such things as a private ground, a kitchen in the south, etc. while interior plans include to provide selection of the korean traditional style, natural or casual one. 'korean traditional style' apartment is one of such theme of the brand-named apartment. Interests on 'Tradition' can be broken down into a social trend and media trend. Firstly, the former includes the designation of Bukchon as a reserving area, one of the governmental 'Hanok Survival Program', and traditional building promotion scheme on the basis of construction policy plans. Secondly, the latter covers the interests which attract through the media showing oriental cosmetics, korean culture export via Hallyu, popularity of korean dramas, etc. Thus, it seems worth studying on the apartments with traditional factors. And also, this study aims to setup the concept and trends of korean traditional style apartments through the interior expression on the korean-factor space developed by brand-name apartments so that it could correct such false knowledge out of misunderstood concept of traditional space which results from simple decoration or structure type not accompanying Korean emotion or spirit rendered by some misleading media.
This study was to find the perception of mathematical & scientific learning of North Korean students who lived in Korea. To understand their perception, three groups as the focus group for clinical interview, consisting of North Korean students, their teaches and their parents, were investigated through narrative description of qualitative method, North Korean students experienced the gap between what they had learned and what they learned in Korea, due to visiting the 3rd country before they came to Korea. So they were in need of well developed instructional instruments based on a precise diagnosis of language ability to help them get over their difficulties. Second, they have difficulties in math & science classes due to differences between curricular and to the differences between the ways of expression of terminologies used in two countries. They expressed that the group work in learning and a great deal of number of problems could be helpful for their needs. Third, the community-service center should be operated in a systematic way to compensate their lack of getting a private education. Fourth, they thought that the supplemental materials should provide some sources that might help them to get over the language barrier and difficulties from the differences, because they depended on them.
Park, Won-Young;Kim, Min Soo;Kim, Min-Seok;Oh, Min-Hee;Lee, Su-Young;Kim, Sun-Hun;Cho, Jin-Hyoung
The korean journal of orthodontics
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v.49
no.5
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pp.299-309
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2019
Objective: This study aimed to investigate the effect of pre-applied orthodontic force on the regeneration of periodontal ligament (PDL) tissues and the underlying mechanisms in tooth replantation. Methods: Orthodontic force (50 cN) was applied to the left maxillary first molars of 7-week-old male Sprague-Dawley rats (n = 32); the right maxillary first molars were left untreated to serve as the control group. After 7 days, the first molars on both sides were fully luxated and were immediately replanted in their original sockets. To verify the effects of the pre-applied orthodontic force, we assessed gene expression by using microarray analysis and real-time reverse transcription polymerase chain reaction (RT-PCR), cell proliferation by using proliferating cell nuclear antigen (PCNA) immunofluorescence staining, and morphological changes by using histological analysis. Results: Application of orthodontic force for 7 days led to the proliferation of PDL tissues, as verified on microarray analysis and PCNA staining. Histological analysis after replantation revealed less root resorption, a better arrangement of PDL fibers, and earlier regeneration of periodontal tissues in the experimental group than in the control group. For the key genes involved in periodontal tissue remodeling, including CXCL2, CCL4, CCL7, MMP3, PCNA, OPG, and RUNX2, quantitative RT-PCR confirmed that messenger RNA levels were higher at 1 or 2 weeks in the experimental group. Conclusions: These results suggest that the application of orthodontic force prior to tooth replantation enhanced the proliferation and activities of PDL cells and may lead to higher success rates with fewer complications.
Moon, Yi Ji;Lee, Jung;Choo, In Sil;Kang, Sung Han;Kim, Cho Hee;Song, In Gyu;Kim, Min Sun
Journal of Hospice and Palliative Care
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v.23
no.4
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pp.212-227
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2020
Purpose: This study presents the process of designing workbooks for advance care planning appropriate for the Korean cultural setting and describes actual case studies. Methods: This study focused on single inductive case studies of the utilization of an advance care planning workbook and recruited individual participants. Results: The workbook for adolescents contained six sessions and the workbook for children contained seven sessions. The workbook sessions led to four major discoveries: 1) considering the Korean cultural context, discussions on life and death must be held indirectly; 2) the role of the counselor as a supporter is crucial for the workbook to be effective; 3) the workbook must be accessible regardless of the seriousness of the illness; and 4) patients must be able to make their own choice between the workbook versions for children and adolescents. Six facilitating factors improved engagement: 1) the role of the counselor as a supporter; 2) building trust with the patient; 3) affirming freedom of expression on topics the patient wished to avoid talking about; 4) having discussions on what private information to keep secret and to whom the information can be disclosed; 5) discovering and regularly discussing relevant topics; and 6) regular communication and information-sharing with the patient's medical service providers. Conclusion: It is necessary to build on actual case studies regarding workbooks for children and adolescents in order to expand the usage of these workbooks to all relevant medical institutions in Korea.
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