• 한국의학물리학회지:의학물리
• /
• 제18권2호
• /
• pp.98-106
• /
• 2007

2005년 6월 연세의료원 세브란스병원에서는 진단목적으로 20대의 5 mesa 화소 Totoku ME511L 평판 LCD 표시장치를 추가하여 PACS를 확장하였다. 20대의 Totoku ME511L 표시장치를 대상으로 반사, 휘도 반응, 휘도 공간 의존, 분해능, 잡음, 베일링 그레어, 그리고 색도 항목에 대하여 AAPM TG 18보고서에 기준하여 정량적인(또는 시각적인) 인수검사를 실시하였다. 측정에 사용된 장치는 색도를 측정할 수 있는 만원경식 휘도계, 조도계, 반사 측정에 필요한 빛 선원, 빛 차단 장치, 그리고 TG18 테스트 패턴들이었다. 선택된 8대의 표시장치에 대한 평균 확산 반사계수($R_d$)는 $0.019{\pm}0.02sr^{-1}$이었다. 휘도 반응 검사에서, 휘도비(LR), 최대 휘도 변이($L_{max}$), 그리고 최대 대조도 반응 변이는 각각 $550{\pm}100,\;2.0{\pm}1.9%$, 그리고 $5.8{\pm}1.8%$이었다. 휘도 균일도 검사에서, 최대 휘도 변이는 TG18-UNL10 테스트 패턴의 10% 휘도에 대하여 $14.3{\pm}5.5%$이었다. 분해능 측정은 휘도 측정법으로 수행하였으며 중심에서 퍼센트 휘도(${\Dalta}L$)는 $0.94{\pm}0.64%$이었다. 시각적인 방법의 잡음측정의 모든 경우에서, 중앙 및 주위 4사분면에서 가장 작은 것을 제외하고 15개의 모든 정사각형의 표적을 인식할 수 있었다. 글레어 비(GR)은 $12,346{\pm}1,995$이었다. 최대 색도 균일도 지표(D)는 $0.0025{\pm}0.0008$이었다. 또한 국내 실정에 적합한 진단용 표시장치의 정도관리 가이드라인 연구 결과를 제시하였다. 모든 인수검사 결과는 AAPM TG18 보고서 기준에 포함되어 진단 목적으로 사용하기에 적합하였다. 결론으로 인수검사는 표시장치가 진단에 사용하기에 적합한 성능임을 알려줄 뿐만 아니라 정도관리의 가이드라인, 최적 판독 환경, 그리고 표시장치의 교체시기를 결정하여주는 중요한 역할을 할 수 있다.

• 한국융합학회논문지
• /
• 제12권12호
• /
• pp.443-451
• /
• 2021

본 연구는 장애인 및 보호자를 대상으로 2021년 2월 9일부터 2월 17일까지 포커스그룹 인터뷰를 실시하여 장애인이 인식하는 미충족 의료와, 장애인 건강주치의 2차 시범사업 관련 경험을 분석하기 위해 수행하였다. 포커스그룹 인터뷰는 시범사업에 등록하였으며 의사표현이 가능한 장애인 5인(그룹 1)과 의사표현이 불가능한 장애인의 보호자 5인(그룹 2)으로 구성되는 두 그룹에 대해 실시하였고, 각 그룹 당 약 100분의 면담을 1회 진행하였다. 장애인의 미충족 의료와 관련된 요인은 의료서비스 이용자, 의료서비스 공급자, 제도적, 사회문화적 측면에서 도출되었고, 이 중 장애인 건강주치의 시범사업 참여를 통해 충족된 요인과 충족되지 않은 요인으로 분석되었다. 향후 장애인의 미충족 의료를 해결하기 위해 방문서비스 확대 적용, 다양한 진료과로 주치의 범위를 확대, 물리치료사나 작업치료사 등을 포함한 다학제적 접근, 서비스 단절 최소화를 위해 병원간 연계 활성화, 장애인 당사자 의견수렴을 통한 서비스 개선, 적극적인 홍보를 통한 본사업의 확대 적용이 필요하겠다.

• Journal of Ginseng Research
• /
• 제43권2호
• /
• pp.305-311
• /
• 2019

Background: Gintonin is a ginseng-derived exogenous ligand of the G protein-coupled lysophosphatidic acid (LPA) receptor. We previously reported that gintonin stimulates gliotransmitter release in primary cortical astrocytes. Astrocytes play key roles in the functions of neurovascular systems. Although vascular endothelial growth factor (VEGF) is known to influence the normal growth and maintenance of cranial blood vessels and the nervous system, there is little information about the effect of gintonin on VEGF regulation in primary astrocytes, under normal and hypoxic conditions. Methods: Using primary cortical astrocytes of mice, the effects of gintonin on the release, expression, and distribution of VEGF were examined. We further investigated whether the gintonin-mediated VEGF release protects astrocytes from hypoxia. Results: Gintonin administration stimulated the release and expression of VEGF from astrocytes in a concentration- and time-dependent manner. The gintonin-mediated increase in the release of VEGF was inhibited by the LPA1/3 receptor antagonist, Ki16425; phospholipase C inhibitor, U73122; inositol 1,4,5- triphosphate receptor antagonist, 2-APB; and intracellular $Ca^{2+}$ chelator, BAPTA. Hypoxia further stimulated astrocytic VEGF release. Gintonin treatment stimulated additional VEGF release and restored cell viability that had decreased due to hypoxia, via the VEGF receptor pathway. Altogether, the regulation of VEGF release and expression and astrocytic protection mediated by gintonin under hypoxia are achieved via the LPA receptor-VEGF signaling pathways. Conclusion: The present study shows that the gintonin-mediated regulation of VEGF in cortical astrocytes might be neuroprotective against hypoxic insults and could explain the molecular basis of the beneficial effects of ginseng on the central nervous system.

• 교육녹색환경연구
• /
• 제13권2호
• /
• pp.35-43
• /
• 2014

Under the influence of birth control and rapid urbanization, China's rural school-age population is on a year-by-year decrease, which has led approximately 300 thousand middle and primary schools to idleness ever since 2000. A majority of these idle schools are located in rural areas, almost one half remaining idle due to vagueness in property right. The disposed schools are less efficient for not being combined with the real situation of rural areas. Based on the opportunity of coordinative development of urban-rural areas, this paper analyzes the situationsin terms of the development of public service facilities and the gap between rural and urban areas over the recent years. Then the effective and sustainable reuse scheme to dispose of the idle schools and reshape them into the facilities for the elders, cultural facilities and medical facilities is proposed from the perspectives of perfecting rural public service facilities and guaranteeing citizens' equal share of public service, which both maintains the public nature of the idle schools, reconciles the fuzzy property right, and boosts efficiency of reuse, saves resources, and reduces investment for perfecting rural public facilities.

• 혜화의학회지
• /
• 제21권1호
• /
• pp.163-174
• /
• 2012

Objective: The primary objective this study was to evaluate the effect of Paljeong-san (PJS) pharmacopuncture treatment on against the glycerol-induced acute renal failure in rats. Methods: Glycerol injection decreased GFR (glomerular filtration rate) and increased urine volume, serum creatinine, BUN level, urine albumine secretion and fractional excretion of Na+, K+. PJS was selected in the basis of invigorating kidney which can eliminate pathogens. Rats were treated with PJS pharmacopuncture on Shin-shu (BL23) and Chon-chu (ST25) point for 3 days, followed by 50% concentration of glycerol injection ($5m{\ell}/kg$ body weight). Results: After the 3 days treatment period, Paljeong-san (PJS) pharmacopuncture treatment improved renal function. In addition, Glycerol injection increased lipid peroxidation, and decreased Na-K-ATPase in renal cortex and which were prevented by PJS treatment. Conclusion: This study suggests that Paljeong-san (PJS) pharmacopuncture treatment show favorable effect on glycerol-induced acute renal failure in rats.

• 성인간호학회지
• /
• 제25권4호
• /
• pp.444-453
• /
• 2013

Purpose: The purpose of this study was to describe the differences between early and delayed enteral nutrition on nutritional intake. Methods: A pilot cohort study was conducted with 45 critically ill adult patients who had a primary medical diagnosis. Energy prescribed and received were collected during the four days after initiation of enteral nutrition. Adequate feeding was defined as the energy intake more than 90% of required energy. Results: A total of 23 patients (52%) were received early enteral nutrition (within 48 hours of admission). Energy intake of early enteral nutrition was less than intake of delayed enteral nutrition during the four days of the study. Although the difference on day one was significantly greater than the differences on day two, the differences on day two were not different from days three or four. No statistical differences in the adequacy of nutritional intake were found between patients in the early and the delayed group. Conclusion: In critically ill patients receiving early enteral nutrition, more aggressive administration from the beginning will improve the nutritional intake. Additional studies including a large multi-centre, randomized clinical trial are recommended.

• 혜화의학회지
• /
• 제12권2호
• /
• pp.85-103
• /
• 2004

From the studies on a few specific chapters of Tibetan Medical Painting, following conclusions were obtained. 1. The doctors of Tibet had to be not only academically and morally perfect, but he must show and have respect for his religion and his religous leaders and Gods. 2 The most main causes for all the disease that Tibetan Medicine resumed were hatred, delusion and ignorance of human mind which can make the physiological bile, wind, and phlegm to turn into pathological ones. 3. There is the classification of primary cause, which would be the human mind mentioned above, and the secondary cause which include dietary, behavior, seasonal problems, etc. 4. The Tibetans thought the digestive power is very important in the improvement or degravation of the disease. 5. More chapters were held for explaining the disease of fever, its clssification, stages, and cures which can indirectly show that the Tibetans might have thought it was very serious and could be very harmful. 6. The treatments for all the kinds of disease not only include medication and external therapy but also dietary and behavior regulations.

• 통상정보연구
• /
• 제14권3호
• /
• pp.381-403
• /
• 2012

본 연구는 한국의 교역 1위 대상국인 중국과의 FTA에 대비하여 국가경쟁력을 강화하기 위한 전략적 연구의 일환으로 한 중 FTA협상에서 비교적 간과되고 있는 한 중간 기술무역에 초점을 맞추었다. 이를 위해 한 중간의 기술무역의 현황을 파악하고 한 중 기술무역의 특징 및 무역장벽을 분석한 다음, 향후 중국과의 기술무역 경쟁력 강화를 위한 대응방안을 모색하는 데 그 목적을 두고 있다. 연구결과, 한국 최대의 기술수출국인 중국과는 기술격차가 점차 줄어들면서 세부산업별 무역특화지수에서 비교열위품목이 늘어나고 있으며 중국의 기술장벽은 비교적 높은 것으로 나타나고 있어, 한 중 FTA를 앞두고 대중국 기술수출에 대한 대응방안이 시급하다는 것을 알 수 있다.

• Journal of electromagnetic engineering and science
• /
• 제16권4호
• /
• pp.248-253
• /
• 2016

Two substrate integrated waveguide (SIW)-based antennas for the application of software-defined radar are proposed and investigated herein. It is usually well known that SIWs are easily integrated, lightweight, have low insertion loss, and low interference levels compared to conventional microstrip structures. The primary function of the proposed antennas is to transmit continuous waves for indoor motion detection, with the lowest amount of loss and an appropriate amount of gain. Moreover, the results of this study show that the size of the antenna can be reduced significantly (i.e., by about 40%) by applying a meander line structure. The operating frequencies of the proposed antennas are both within the industrial, scientific, and medical band (i.e., 2.4-2.4835 GHz). Measured results of return loss are -16 dB and -20 dB at 2.435 GHz and 2.43 GHz, respectively, and the measured gain is 8.2 dBi and 5.5 dBi, respectively. Antenna design and verification are undertaken through commercially available full electromagnetic software.

• 한국자기공명학회논문지
• /
• 제11권1호
• /
• pp.10-23
• /
• 2007

A new disintegrin protein named saxatilin was purified from Korean snake venom (Gloydius saxatilis). Saxatilin is a 73 residue small ploypeptide, which has a primary recognition motif in extracellular matrix, Arg-Gly-Asp (RGD) sequence. Data from inhibition activity assay for the ${\alpha}_v{\beta}_3$ integrin showed that saxatilin showed about 5000-fold higher activity than those of RGD peptides, suggesting that RGD sequence may not be sufficient to induce full cellular function of this site. The solution structures calculated from NMR data were well converged for backbone atoms except RGD loop. The structure revealed that most of tight turns are stabilized by medium range NOE contacts and the RGD motif is located far from the rigid core of the C-terminal domain. The three-dimensional fold and biological function of saxatilin are discussed with those of salmosin, which is a disintegrin protein derived from Agkistrodon halys brevicaudus.