• Korean Institute of Interior Design Journal
• /
• v.27 no.1
• /
• pp.48-57
• /
• 2018

Recently, cosmetic shops are facing a complicate economy situation and a great number of brands are attempting two-way communication with customers, not one-way communication. 'Brand' equity is important to deliver virtual brand mark as visual image. We have 4 steps for brand identity structure, and this study is about the first 'brand-awareness' and the second step 'brand-image'. We investigated the correlation between brand-awareness and brand-image after searching which spatial elements are highly effective to both steps as we designated 5 cosmetic shops. We already organized the means of spatial analysis and we separated into two elements, constructive and decorative. For constructive element, a shop needs a distinct ceiling and wall design, and for decorative element, strong brand image communication is required through showcase design. We proved that brand awareness and brand image have the correlation, which also can be in direct proportion, by regression analysis. The result of this study shows that improving brand awareness as the primary element for cosmetic road shop can be an effective way to enhance brand image.

• Journal of Chest Surgery
• /
• v.12 no.3
• /
• pp.151-158
• /
• 1979

This is a report of 3 cases of tumors, which primarily originated from ribs and the sternum. In the first case of multiple myeloma, the patient was 67 year old male with a tumor located on the middle sternum invading the manubrium and the body of the sternum manifesting symptoms after a contusion of the anterior sternum. The sternum was entirely resected and was replaced by tantalum plate to reconstruct the defective chest wall in order to prevent the paradoxical movement during respiration. In the second case of osteogenic sarcoma, the patient was 43 year old male with a tumor located on the costochondral junction of the left 5th rib for 6 months. The left 5th rib was resected between the middle part and sternochondral junction of it including tumor and adjacent soft tissues. In the third case of chondrosarcoma, the patient was 36 year old male with a tumor located near the posterior angles of the right 7th and 8th ribs manifesting back pain on the area where the tumor was located. Resection of right lower lobe was performed since direct invasion of tumor was seen in the superior segment of right lower lobe. This was followed by the resection of both 7th and 8th ribs at the area between the costovertebral junction and the portion 10 em apart from the tumor including the tumor and intercostal soft tissues. Diagnoses of 3 cases of tumors described above were confirmed by histopathologic examination postoperatively. The postoperative courses were uneventful.

• 한국신재생에너지학회:학술대회논문집
• /
• 2009.11a
• /
• pp.594-599
• /
• 2009

Recent developments such as concern over global warming, depletion of fossil fuels and increase in energy demands by the increasing world population has eventually lead to mass production of electricity using renewable sources. Apart from wind and solar, ocean holds tremendous amount of untapped energy in forms such as geothermal vents, tides and waves. The current study looks at generating power using waves and the focus is on the primary energy conversion (first stage conversion) of incoming waves for different models. Observation of flow characteristics and the velocity in the augmentation channel as well as the front guide nozzle are presented in the paper. A numerical wave tank was used to simulate the waves and after obtaining the desired wave properties; the augmentation channel plus the front guide nozzle and rear chamber were integrated to the numerical wave tank. The waves in the numerical wave tank were generated by a piston type wave maker which was located at the wave tank inlet. The inlet which was modeled as a plate wall moved sinusoidally with the general function, x=asin$\omega$t The augmentation channel consisted of a front nozzle, rear nozzle and an internal fluid region representing the turbine housing. The analysis was performed using the commercial CFD code ANSYS-CFX.

• The Korean Journal of Legal Medicine
• /
• v.42 no.4
• /
• pp.159-163
• /
• 2018

Progressive muscular dystrophy (PMD) is a primary muscle disease characterized by progressive muscle weakness and wasting, which is inherited by an X-linked recessive pattern and occurs mainly in males. There are several types of muscular dystrophies classified according to the distribution of predominant muscle weakness including Duchenne and Becker, Emery-Dreifuss, facioscapulohumeral, oculopharyngeal, and limb-girdle type. Clinical manifestations of PMD are clumsy, unsteady gait, pneumonia, heart failure, pulmonary edema, hydropericardium, hydrothorax, aspiration, syncopal attacks, and sudden cardiac death. The deceased was a 34-year-old man, and the onset of the first clinical symptom, gait disturbance, was in his late teens. His elder brother had the same disease and experienced brain death after a head trauma and died after mechanical ventilation was discontinued. After an autopsy, we found contracture of the joints, pseudohypertrophy of the calf, wasting and fat replacement of the thigh muscle, pericardial effusion (80 mL), fibrosis and fat replacement of the cardiac ventricular wall, pulmonary edema, and froth in the bronchus. The cause of death was heart failure and dyspnea due to muscular dystrophy. There was no sign or suspicion of foul play in his death.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.6
• /
• pp.460-468
• /
• 2021

This study investigated the enhanced combustion efficiency of an "air-cooled combustion system" with single F.D. fan, and performed a numerical analysis for the operation and design conditions to increase the combustion efficiency. The combustion efficiency in an actual combustor was compared before and after the structure modification. Numerical analysis for application of a single fan revealed the difficulty of forming a turbulence for circular combustion conditions. This is because the supply ratio of combustion air supplied into 2 flow paths becomes irregular in the combustion furnace due to a change in friction force and pressure in each flow path. Subsequently, two methods of supplying air into the combustion furnace were analyzed numerically to obtain the optimal combustion conditions of an air-cooled combustion system. The first method involved injecting the preheated combustion air after a 180~360 degree rotation from the outer wall, whereas in the second method, the combustion air was injected into the combustion furnace in a tangential direction after primary heat exchange outside the combustion furnace, by applying a rotatable vane structure in the combustion furnace. Results reveal that application of a single F.D. fan to the air injection into a rotatable combustion furnace is desirable for optimization of the combustion conditions for applying a duct structure having a dual cooling wall for the cooling of the outer wall of the combustion furnace, and for maintaining perfect mixing in the combustion furnace. We therefore confirmed enhanced combustion efficiency by comparing the actual combustion efficiency before and after structure modification.

• Journal of the Korean Institute of Rural Architecture
• /
• v.19 no.2
• /
• pp.9-16
• /
• 2017

The study analyzed the heat losses and the building energy efficiency grade by the energy simulation using the ENERGY# and ECO2 programs for the three types of Standard design of rural houses. It was calculated the energy efficiency rating by the ECO2 program for the rural housing standard design, and the energy demand and the energy consumption by each factor were compared and analyzed. And it analyzed energy consumption by element of each house by ENERGY # program. As a result, first in the evaluation of the energy efficiency grade of buildings by the ECO2 program, the rating for primary energy requirement for the housing newly built by the standard design of rural house is expected to range from 2 to 4 with 189.3 to $238.7kWh/m^2.a$. Second, the energy loss of each part of standard design of rural housing occurs in the order of ventilation 39%, window 33%, outer wall 14%, roof 9%, bottom 5%, and energy loss through ventilation and window occurs more than 70%. Third, the most beneficial effects on the energy efficiency grade is obtained the lowest grade of all three types by 2 when the lowering of the window and door heat transmission rate and the lowering of the light density, and the heat exchange ventilation device is not installed. Fourth, in the standard design of rural housing, the energy demand is occupied by heating > hot water > lighting order, and the order of the weight is changed in order of heating > lighting > ventilation > hot water. Fifth, building energy efficiency assessment system needs to establish policy for fixing rural housing energy as a practical device to ensure energy performance and quality.

• Biomolecules & Therapeutics
• /
• v.22 no.2
• /
• pp.143-148
• /
• 2014

Marfan syndrome (MFS) is a dominantly inherited connective tissue disorder caused by mutations in the gene encoding fibrillin-1 (FBN1) and is characterized by aortic dilatation and dissection, which is the primary cause of death in untreated MFS patients. However, disease progression-associated changes in gene expression in the aortic lesions of MFS patients remained unknown. Using a mouse model of MFS, FBN1 hypomorphic mouse (mgR/mgR), we characterized the aortic gene expression profiles during the progression of the MFS. Homozygous mgR mice exhibited MFS-like phenotypic features, such as fragmentation of elastic fibers throughout the vessel wall and were graded into mgR1-4 based on the pathological severity in aortic walls. Comparative gene expression profiling of WT and four mgR mice using microarrays revealed that the changes in the transcriptome were a direct reflection of the severity of aortic pathological features. Gene ontology analysis showed that genes related to oxidation/reduction, myofibril assembly, cytoskeleton organization, and cell adhesion were differentially expressed in the mgR mice. Further analysis of differentially expressed genes identified several candidate genes whose known roles were suggestive of their involvement in the progressive destruction of aorta during MFS. This study is the first genome-wide analysis of the aortic gene expression profiles associated with the progression of MFS. Our findings provide valuable information regarding the molecular pathogenesis during MFS progression and contribute to the development of new biomarkers as well as improved therapeutic strategies.

• Journal of Veterinary Clinics
• /
• v.29 no.3
• /
• pp.242-246
• /
• 2012

A 3-year-old castrated male Korean domestic short-haired cat (weighing 5.2 kg) was referred to the Kangwon National University Veterinary Teaching Hospital, with primary complaints of ascites, pleural effusion and respiratory distress. Diagnostic studies revealed marked chylous and hemorrhagic pleural effusion, cardiomegaly, restrictive filling pattern of transmitral flow and mitral annular tissue Doppler profiles and minimally thickened left ventricular free wall. Based on the echocardiographic findings, the case was tentatively diagnosed as restrictive cardiomyopathy. The case was treated with removal of pleural effusion and medical therapy including furosemide, enalapril, sildenafil, clopidogrel. This is the first case report of restrictive cardiomyopathy in Korea.

• Proceedings of the KOR-BRONCHOESO Conference
• /
• 1983.05a
• /
• pp.18.1-18
• /
• 1983

In 1923 Pierre-Robin first described the triad of micrognathia, glossptosis and high-arched or cleft palate. Respiratory distress is not an uncommon occurrence and requires prompt and appropriate treatment. The syndrome occurs once in approximately 50,000 births. Although the etiology of the syndrome is obscure, it is known that the syndrome probably results from a primary deficiency early in fetal life of mandibular development. The symptoms of airway obstruction develop as the base of the tongue falls posteriorly and approximates the posterior pharyngeal wall because of micrognathia, and is aggravated when the infant is in the supine position. The problems of mild airway obstruction can be solved by keeping the infant in the prone position. In case there are feeding difficulties, prompt glossopexy should be preformed as airway is aggravated, but tracheostomy is best avoided. There is some forms of glossopexy including Douglas operation, the insertion of Kirschner wire and Duhamel suture. We identified micrognathia, glossoptosis and high-arched palate in a 2-month-old infant who was brought to our hospital with complaints of dyspnea and feeding difficulties, and we reports this case, since we think this infant whom we observe after tracheostomy because we found Duhamel suture could not relieve the symptoms of airway obstruction as Pierre-Robin syndrome.

• Molecules and Cells
• /
• v.46 no.12
• /
• pp.746-756
• /
• 2023

A recent study revealed that the loss of Deup1 expression does not affect either centriole amplification or multicilia formation. Therefore, the deuterosome per se is not a platform for amplification of centrioles. In this study, we examine whether gain-of-function of Deup1 affects the development of multiciliated ependymal cells. Our time-lapse study reveals that deuterosomes with an average diameter of 300 nm have two different fates during ependymal differentiation. In the first instance, deuterosomes are scattered and gradually disappear as cells become multiciliated. In the second instance, deuterosomes self-organize into a larger aggregate, called a deuterosome cluster (DC). Unlike scattered deuterosomes, DCs possess centriole components primarily within their large structure. A characteristic of DC-containing cells is that they tend to become primary ciliated rather than multiciliated. Our in utero electroporation study shows that DCs in ependymal tissue are mostly observed at early postnatal stages, but are scarce at late postnatal stages, suggesting the presence of DC antagonists within the differentiating cells. Importantly, from our bead flow assay, ectopic expression of Deup1 significantly impairs cerebrospinal fluid flow. Furthermore, we show that expression of mouse Deup1 in Xenopus embryos has an inhibitory effect on differentiation of multiciliated cells in the epidermis. Taken together, we conclude that the DC formation of Deup1 in multiciliated cells inhibits production of multiple centrioles.