• Title/Summary/Keyword: Primary damage

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Design of a Dual-Drive Mechanism for Precision Gantry

  • Park, Heung-Keun;Kim, Sung-Soo;Park, Jin-Moo;Daehie Hong;Cho, Tae-Yeon
    • Journal of Mechanical Science and Technology
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    • v.16 no.12
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    • pp.1664-1672
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    • 2002
  • Gantry mechanisms have been widely used for precision manufacturing and material handling in electronics, nuclear, and automotive industries. Dual-drive servo mechanism is a way to increase control bandwidth, in which two primary axes aligned in parallel are synchronously driven by identical servo motors. With this mechanism, a flexible coupling (compliance mechanism) is often introduced in order to avoid the damage by the servo mismatch between the primary drives located at each side of gantry. This paper describes the design guidelines of the dual-drive servo mechanism with focus on its dynamic characteristics and control ramifications. That is, the effect on the system bandwidth which is critical on the system performance, the errors and torques exerted on guide ways in case of servo mismatch, the vibration characteristics concerned with dynamic error and settling time, and the driving force required at each axis for control are thoroughly investigated.

Analysis of Electromagnetic Field Around Distribution Line (배전선로 주변에서의 전자계 분포 해석)

  • Kwon, Myung-Rak
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.30 no.10
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    • pp.672-676
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    • 2017
  • Electrical energy is playing an increasingly vital role as the primary energy source in everyday life. With the increase in electric power consumption, power facilities are under an increasing stress and must operate at a high capacity. Consequently, the demand for electric power cables in power transmission and distribution lines is rapidly increasing. Underground distribution lines have been steadily replacing the aboveground lines owing to the increase in electric power demand and the need to increase the supply voltage. In addition to line damage, worker safety is of primary concern in this type of underground infrastructure. In this study, to improve the safety of workers dealing with underground transmission lines, we analyzed the electromagnetic field generated around the distribution line and determined the basic criteria for developing a device that can detect a live underground line.

Displacement of deciduous tooth into hypopharynx due to endotracheal intubation

  • Kang, Sang-Hoon;Chang, Jung Hyun
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.16 no.1
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    • pp.61-65
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    • 2016
  • Intubation may lead to several dental complications. Furthermore, a tooth damaged during intubation may be subsequently dislocated. In the present case, the upper primary incisor was avulsed during intubation and, unbeknownst to the anesthesiologist, displaced to the larynx. We report here on the findings and indicate appropriate treatment. Intubation for general anesthesia in children can result in tooth damage and/or dislocation of primary teeth with subsequent root resorption. Prevention is key, and thus it is critical to evaluate the patient's dental status before and after intubation. Furthermore, anesthesiologists and dentists should pay close attention to this risk to prevent any avulsed, dislocated, or otherwise displaced teeth from remaining undetected and subsequently causing serious complications.

Effects of Scoparone on Liver Function (Scoparone의 간 기능에 대한 영향)

  • 최석영;조민경;홍순명;김병삼
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.2
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    • pp.344-349
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    • 1998
  • The purpose of this study was carried out to investigate the effect of scoparone(6, 7-dimethoxyco-umarin) on liver function. Sprague-Dawley rats were treated with scoparone at a dose of 20mg/kg body weight for 5 days. Hepatic bile flow, liver weight, BSP(bromosulfophthalein) biliary excretion, alanine aminotransferase(ALT) and aspartate aminotransferase(AST) activities, malondialdehyde production and lactate dehydrogenase(LDH) release were assayed. Among them, ALT and AST activities, malondialdehyde production and LDH release were assayed by using primary hepatocyte cultures at a concentration of 0.1mg/ml. Scoparone treatment had no effect on liver weight and hepatic bile flow. Scoparone treatment not only increased BSP biliary excretion, but also recovered the decreased BSP biliary excretion by CCl4, Also scoparone significantly decreased with the increases of ALT and AST activities, malondialdehyde production and LDH release induced by CCl4. These results suggested that scoparone could protect the liver damage by chemicals via promoting the liver excretory function.

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UNERUPTED PRIMARY MOLAR (미맹출 유구치에 관한 증례)

  • Han, Yeon-Sun;Choi, Byung-Jai;Kim, Seong-Oh;Lee, Chong-Gap
    • Journal of the korean academy of Pediatric Dentistry
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    • v.29 no.3
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    • pp.444-449
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    • 2002
  • The term 'impaction' is used to designate a tooth which remains unerupted in the jaw beyond the time at which it should normally be erupted. The main causal factors are local (lack of space, ectopic positions of teeth, supernumerary teeth, cyst, the occurrence of infectious process in the eruption path, traumatic facial injury etc.). Systemic and genetic disorders, however, may have primary failure of eruption and retarded eruption as additional symptoms (cleidocranial dysplasia, osteopetrosis etc.). Most cases of impacted teeth reported in the literature are of permanent teeth. The absence of primary teeth occur rarely whereas impaction of second primary molars is more numerous than all other impactions. Impaction due to primary failure of eruption must be distinguished from the secondary infraocclusion. The etiology of impaction of primary teeth is probably related to early ankylosis of primary teeth, but it is not clear. Failure of eruption of primary teeth may cause a number of complications, such as interference with development and eruption of succedaneous teeth, formation of cyst, and damage to adjacent teeth. This study is to report cases of primary failure of eruption in the primary dentition.

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In vivo Comet Assay on Flounder and Clam Exposed to BaP and TBT (BaP 및 TBT에 노출된 넙치와 개조개의 in vivo Comet assay)

  • Kim, So-Jung;Chung, Young-Jae;Lee, Taek-Kyun
    • Ocean and Polar Research
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    • v.33 no.2
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    • pp.127-133
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    • 2011
  • The comet assay, also called single-cell electrophoresis (SCGE) assay, is a potential sensitive monitoring tool for DNA damage in cells. The primary objective of this study was to use comet assay to ascertain if the blood cells of flounder (Pleuronichthys olivaceus) and muscle cells of clam (Saxidomus purpurata) are suitable for genotoxicity screening. This was achieved by initially exposing blood and muscle cells under in vitro conditions to the reference genotoxin hydrogen peroxide ($H_2O_2$); strong correlation between $H_2O_2$ concentration and comet values were found. Subsequently, the identification of DNA damage in isolated cells from flounder and clam was performed under in vivo exposure to benzo(a)pyrene (BaP) and tributyltin (TBT). Flounder and clam were exposed to different concentrations (1, 10, 50, 100 ${\mu}g/L$) of BaP or TBT for 4 days. Regardless of treated chemicals, blood cells of flounder were more prone to DNA breakage compared to muscle cells of clam. In conclusion, in vivo genotoxicity of BaP and TBT can be biomonitored using the comet assay. This study suggests that flounder and clam do show potential as mediums for monitoring genotoxic damage by comet assay.

Heat Shock Proteins as Molecular Chaperons in Neuropsychiatry (열충격 단백질의 신경정신의학적 의의와 중요성)

  • Oh, Dong-Hoon;Yang, Byung-Hwan;Choi, Joonho
    • Korean Journal of Biological Psychiatry
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    • v.14 no.4
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    • pp.221-231
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    • 2007
  • Recent researches have shown that important cellular-based autoprotective mechanisms are mediated by heat-shock proteins(HSPs), also called 'molecular chaperones'. HSPs as molecular chaperones are the primary cellular defense mechanism against damage to the proteome, initiating refolding of denatured proteins and regulating degradation after severe protein damage. HSPs also modulate multiple events within apoptotic pathways to help sustain cell survival following damaging stimuli. HSPs are induced by almost every type of stresses including physical and psychological stresses. Our nervous system in the brain are more vulnerable to stress and damage than any other tissues due to HSPs insufficiency. The normal function of HSPs is a key factor for endogenous stress adaptation of neural tissues. HSPs play an important role in the process of neurodevelopment, neurodegeneration, and neuroendocrine regulation. The altered function of HSPs would be associated with the development of several neuropsychiatric disorders. Therefore, an understanding of HSPs activities could help to improve autoprotective mechanism of our neural system. This paper will review the literature related to the significance of HSPs in neuropsychiatric field.

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Development of Web-based Design Compatibility Assessment Program for High Temperature Reactor (고온로 설계 적합성평가 프로그램 개발)

  • Cho, Doo Ho;Surh, Han Bum;Choi, Jae Boong;Huh, Nam Su;Choi, Young Hwan
    • Transactions of the Korean Society of Pressure Vessels and Piping
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    • v.9 no.1
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    • pp.48-55
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    • 2013
  • In this paper, W-DCAP-HTR(Web-based Design Compatibility Assessment Program for High Temperature Reactor) which will be used to check the design criteria for high temperature reactor is newly proposed. To do this, the assessment procedure of the ASME Sec.III Div.5 such as time-dependent primary stress limit, accumulated inelastic strain, and creep-fatigue damage evaluation were investigated. Furthermore, the trend of candidate materials for high temperature reactor was also reviewed. Then, all assessment procedures for high temperature reactor have been computerized to enhance the efficiency and to reduce the possibility of human error during calculating procedure by hand calculation. It can be directly conducted by adopting the actual thermal and structural analysis results. The validation of W-DCAP-HTR has been demonstrated by benchmark analysis.

Failure Modeling of Bridge Components Subjected to Blast Loading Part II: Estimation of the Capacity and Critical Charge

  • Quintero, Russ;Wei, Jun;Galati, Nestore;Nanni, Antonio
    • International Journal of Concrete Structures and Materials
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    • v.1 no.1
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    • pp.29-36
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    • 2007
  • The purpose of this paper is the assessment of the capacity of the reinforced concrete (RC) elements of an arch bridge when they are subjected to contact and near-contact explosive charges of various amounts, and the estimation of the critical charges for these components. The bridge considered is the Tenza Viaduct, a decommissioned structure south of Naples, Italy. Its primary elements, deck, piers and arches were analyzed. The evaluation was accomplished via numerical analyses that made possible to obtain the elements dynamic response when they are exposed to blast loading conditions. To evaluate the member's capacities, failure criteria for deck, piers and arches were proposed based on concrete damage parameters. Additionally, curves relating the explosive charge to the residual capacity and to damage level of the elements were also developed. The results of this work were taken into account to investigate the progressive collapse of the global structure.

Effects of 60-Hz Time-Varying Electric Fields on DNA Damage and Cell Viability Support Negligible Genotoxicity of the Electric Fields

  • Yoon, Yeo Jun;Li, Gen;Kim, Gyoo Cheon;Lee, Hae June;Song, Kiwon
    • Journal of electromagnetic engineering and science
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    • v.15 no.3
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    • pp.134-141
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    • 2015
  • The effect of a 60 Hz time-varying electric field was studied using a facing-electrode device (FED) and a coplanar-electrode device (CED) for further investigation of the genotoxicity of 60 Hz time-varying magnetic field (MF) from preceding research. Neither a single 30-minute exposure to the CED or to the FED had any obvious biological effects such as DNA double strand break (DSB) and apoptosis in cancerous SCC25, and HeLa cells, normal primary fibroblast IMR90 cells, while exposures of 60 Hz time-varying MF led to DNA damage with induced electric fields much smaller than those used in this experiment. Nor did repetitive exposures of three days or a continuous exposure of up to 144 hours with the CED induce any DNA damage or apoptosis in either HeLa or IMR90 cells. These results imply that the solitary electric field produced by time-varying MF is not a major cause of DSBs or apoptosis in cancer or normal cells.