• Proceedings of the KSR Conference
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• 2000.05a
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• pp.143-150
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• 2000

Like conventional railways, improving running performance of vehicle in curve is more effective than improving maximum speed to reduce traveling time. But some vehicles have problems concerning running performance in cure because of insufficient study for our conventional railway characteristics. So, these problems brought about increasement of maintenance cost. This study was started to deliberate several plans to solve problems concerning running performance in curve. Some modifications of primary suspension and tests were carried out to improve curve negotiation. Here, we describe some results.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.8
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• pp.773-778
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• 2009

Chevron rubber springs are used in primary suspensions for rail vehicle. Chevron rubber spring have function which reduce vibration and noise, support load carried in operation of rail vehicle. Prediction and evaluation of characteristics are very important in design procedure to assure the safety and reliability of the rubber spring. The computer simulation using the nonlinear finite element analysis program executed to predict and evaluate the load capacity and stiffness for the chevron spring. The non-linear properties of rubber which are described as strain energy functions are important parameters. These are determined by material tests which are uniaxial tension, equi-biaxial tension and shear test. The appropriate shape and material properties are proposed to adjust the required characteristics of rubber springs in the three modes of flexibility.

• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.2
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• pp.99-105
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• 2000

Cell-Cell interaction and the extracellular matrix (ECM) are belisved to play essential roles during in vitro culturing of primary hepatocytes in the control of differentiation and in the maintenance of tissue spcific functions. The objective of this study was to examine the effects of degree of cell-cell contact (DCC) on liver sperific function of rat promary hepatocytes. Hepatocyte aggregates with various with various degrees of cell-cell contantact, I. e., dispersed cell, longish aggregate, rugged aggregate, and smooth spheroid were obtained at 1, 5-6, 15-20, and 36-48 hrs, respectively in suspension cultures grown in spinner flasks embedded in Caalginate bead and collagen gel in order. The may result from mass transfer limitation and shear damage caused by agitation during aggregation. The rugged aggregate showed a higer viability and albumin secretion rate than the dispersed cells or the other aggregates. This result indicates the possible enhancement of a bioartificial liver's (BAL) performance using primary hepatocytes and the reduction in time to prepare a BAL through optimization of the immobilization time.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.11a
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• pp.135-140
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• 1994

Over past decades, numerous in vitro model has been developed to investigate drug metabolism. In the order of complexity we found the isolated perfused liver, hepatocytes in co-culture with epithelial cells, hepatocytes in suspension and in primary culture and subcellular hepatic microsomal fractions. Because they can be easily prepared from both animals (pharmacological and toxicological species) and humans (whole livers as well as biopsies obtained during surgery) hepatocytes in primary culture provide the most powerful model to better elucidate drug behavior at an early stage of preclinical development such as : 1. the characterization of main biotransformation reactions. 2. the identification of phase I and phase II isozymes involved in such reactions 3. the evaluation of interspecies differences allowing the selection of a second toxicological animal species more closely related to man on the basis of metabolic profiles 4. the detection of the inducing and/or inhibitory effects of a drug on metabolic enzymes, the prediction of drug interactions 5. the estimation of inter-individual variability in biotransformation reactions. The use of hepatocytes, and in particular those obstained from humans, at an early stage of drug development allows the obtention of more predictive preclinical data and a better knowledge of drug behavior in humans before the first administration of the drug in healthy volunteers.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1095-1098
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• 2005

Most electronic chassis control systems until today have been designed with optimization on its own performance. However, According to the increase of the interest regarding a vehicle safety and development of information technique, the integration technique of current chassis systems is being emphasized. Each enterprise proposed it with name of GCC(Global Chassis Control) or UCC(Unified Chassis Control). This study realizes control algorithm of suspension and brake by using the vehicle model of low degree of freedom as the primary stage of realization of integrated chassis control system. The proposed algorithm build the simulation environment connected to the CarSim having full vehicle model of 27 degree of freedom for raising the thrust of results

• Journal of Korean Society on Water Environment
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• v.36 no.3
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• pp.185-193
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• 2020

Bimodal flocculation describes the aggregation and breakage processes of the flocculi (or primary particles) and the flocs in the water environment. Bimodal flocculation causes bimodal size distribution with the two separate peaks of the flocculi and the flocs. Extracellular polymeric substances and ionic species common in the water environment increase the occurrence of bimodal flocculation and flocculi-floc size distribution, under the flocculation mechanisms of electrostatic attraction and polymeric bridging. This study investigated bimodal flocculation and flocculi-floc size distribution, with respect to the extracellular polymeric substance concentration and ionic strength in the kaolinite-containing suspension. The batch flocculation tests comprising 0.12 g/L of kaolinite showed that the highest flocculation potential occurred at the lowest xanthan gum (as extracellular polymeric substances) concentration, under all the ionic strengths of 0.001, 0.01, and 0.1 M NaCl. Also, it was important to note that the higher ionic strength resulted in the higher flocculation potential, at all the xanthan gum concentrations. The bimodal flocculation and flocculi-floc size distribution became apparent in the experimental conditions, which had low and intermediate flocculation potential. Besides the polymeric bridging flocculation, steric stabilization increased the flocculi mass fraction against the floc mass fraction, thereby developing the bimodal size distribution.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.10
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• pp.1132-1138
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• 2009

The spring constants of primary suspensions for a railway vehicle are optimized by a robust design process, in which the response surface models(RSMs) of their dynamic responses are constructed via the design of experiment(DOE). The robust design process requires an intensive computation to evaluate exactly a probabilistic feasibility for the robustness of dynamic responses with their probabilistic variances for the railway vehicle. In order to overcome the computational process, the process capability index $C_{pk}$ is introduced which enables not only to show the mean value and the scattering of the product quality to a certain extent, but also to normalize the objective functions irrespective of various different dimensions. This robust design, consequently, becomes to optimize the $C_{pk}$ subjected to constraints, i.e. 2, satisfying six sigma. The proposed method shows not only an improvement of some $C_{pk}$ violating the constraints obtained by the conventional optimization, but also a significant decrease of the variance of the $C_{pk}$.

• Journal of Power Electronics
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• v.15 no.6
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• pp.1508-1516
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• 2015

A single phase H-bridge inverter is employed in conventional Inductive Power Transfer (IPT) systems as the primary side power supply. These systems may not be suitable for some high power applications, due to the constraints of the power electronic devices and the cost. A high-frequency cascaded multi-level inverter employed in IPT systems, which is suitable for high power applications, is presented in this paper. The Phase Shift Pulse Width Modulation (PS-PWM) method is proposed to realize power regulation and selective harmonic elimination. Explicit solutions against phase shift angle and pulse width are given according to the constraints of the selective harmonic elimination equation and the required voltage to avoid solving non-linear transcendental equations. The validity of the proposed control approach is verified by the experimental results obtained with a 2kW prototype system. This approach is expected to be useful for high power IPT applications, and the output power of each H-bridge unit is identical by the proposed approach.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.1
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• pp.29-34
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• 2003

In development of the processed food, it is important not only to make the food delicious but to enhance its storage span and thermal stability without change in color, which greatly affects the tastes. Protopectinase (PPase) from Bacillus subtilis EK11 hydrolyses or dissolves protopectin in the middle lamella of plant tissues with the resultant separation of plant cells from each other, called enzymatic maceration. With the PPase, persimmon was enzymatically macerated to separate cells to primary cell wall without damage. Recovery rates of persimmon treated with PPase and mechanical maceration were 95% and 85%, respectively. Total and reducing sugars, crude protein and fat in the enzymatic maceration were well preserved as in the mechanical maceration. Importantly, over 50% of vitamin C, which is the most unstable component during the mechanical maceration, remained with an intact form for one day after the enzymatic treatment. When the suspensions of persimmon macerated with both treatments were stored at 4$^{\circ}C$ for 9 days, the mechanically macerated persimmon suspension was decolorized, whereas decolorization, was not found in the enzymatically macerated persimmon suspension. Moreover the mechanically macerated persimmon was greatly deteriorated after heat treatment at 10$0^{\circ}C$ for 60 min, whereas cells of the enzymatically separated persimmon suspension appeared to be stable, indicating increased thermal stability Thus, the PPase treatment of persimmon could be a better choice for preparation of highly valuable and functional processed food as well as for increase in preservation period.

• Journal of the Korean Society for Railway
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• v.20 no.3
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• pp.311-319
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• 2017

The primary suspension system of a railway vehicle restrains the wheelset and the bogie, which greatly affects the dynamic characteristics of the vehicle depending on the stiffness in each direction. In order to improve the dynamic characteristics, different stiffness in each direction is required. However, designing different stiffness in each direction is difficult in the case of a general suspension device. To address this, in this paper, an optimization technique is applied to design different stiffness in each direction by using a conical rubber spring. The optimization is performed by using target and analysis RMS values. Lastly, the final model is proposed by complementing the shape of the weak part of the model. An actual model is developed and the reliability of the optimization model is proved on the basis of a deviation average of about 7.7% compared to the target stiffness through a static load test. In addition, the stiffness value is applied to a multibody dynamics model to analyze the stability and curve performance. The critical speed of the improved model was 190km/h, which was faster than the maximum speed of 110km/h. In addition, the steering performance is improved by 34% compared with the conventional model.