• Title/Summary/Keyword: Primary Renal Hemangiosarcoma

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Primary Renal Hemangiosarcoma Complicated with Hematuria and Hemoperitoneum in a Dog (개에서 발생한 혈뇨와 복강 내 출혈을 동반한 신장원성 혈관육종)

  • Yeo, Jung-Jin;Sur, Jung-Hyang;Eom, Ki-Dong;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.29 no.2
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    • pp.165-168
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    • 2012
  • A 14-year-old intact male Siberian Husky was presented with hematuria, lethargy, and anorexia of 1-month duration. The physical examination revealed mild abdominal distension and pain. The hematology and serum chemistry revealed anemia and severe azotemia. The radiographic examination revealed renomegaly and the ultrasonographic examination, indistinct cortico-medullary junction, increased renal cortex echogenicity, and irregular margination. The urinalysis showed proteinuria and hematuria. The differential diagnosis included renal failure, cystitis, pyelonephritis, and neoplasia. The patient's condition continued to deteriorate, and the dog eventually died. The gross findings from the necropsy revealed hemoperitoneum and a bilateral renal mass. HSA was diagnosed by histopathological examination. This case report describes primary bilateral renal hemangiosarcoma (HSA), which is uncommon in dogs.

Immunohistochemical Diagnosis of Primary Renal Hemangiosarcoma in a Dog (개에서 발생한 신장원성 혈관육종의 면역조직화학적 진단)

  • Jung, Soo-Kyo;Yang, Hyoung-Seok;Kim, Jae-Hoon
    • Journal of Veterinary Clinics
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    • v.30 no.4
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    • pp.296-300
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    • 2013
  • A 7-year-old castrated male Yorkshire Terrier was presented with a palpable intra-abdominal mass. In radiography, a large radioopaque renal mass and small abdominal mass were found on dorsal area of the abdomen. Grossly, red to brown color mass and a cystic structure (hydronephrosis) were embedded in the right kidney. Histopathologically, the mass had many irregular shaped neovascular channels lined by polygonal or oval shaped endothelial cells. These vessels and neoplastic cells had great invasive tendency to adjacent connective or fat tissues. Small abdominal mass had identical morphologic features as in renal mass. According to immunohistochemistry, the neoplastic cells in renal mass demonstrated strong positive signals for vimentin and CD31, and weak positive for von Willbrand factor. However, there were no positive reactions for cytokeratin. Based on the gross, histopathology and immunohistochemistry, this mass was diagnosed as primary renal hemangiosarcoma in a Yorkshire Terrier dog.