• Journal of Pharmaceutical Investigation
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• v.32 no.1
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• pp.21-26
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• 2002

The primary culture of human nasal epithelial cell monolayer was performed on a Transwell. The effect of various factors on the tight junction formation was observed in order to develop an in vitro experimental system for nasal transport studies. Human nasal epithelial cells, collected from human normal inferior turbinates, were plated onto diverse inserts. After 4 days, media of the apical surface was removed for air-liquid interface (ALI) culture. Morphological characteristics was observed by transmission electron microscopy (TEM). A polyester membrane of $0.4\;{\mu}m$ pore size was determined as the most effective insert based on the change in the transepithelial electric resistance (TEER) value as well as the $^{14}C-mannitol$ transport study. The ALI method was effective in developing the tight junction as observed in the further increase in the TEER value and reduction in the permeability coefficient $(P_{app})$ of $^{14}C-mannitol$ transport. Results of the transport study of a model drug, budesonide, showed that the primary culture system developed in this study could be further developed and applied for in vitro nasal transport studies.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.11
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• pp.814-824
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• 2020

Recently, public interest in air pollutants has increased, and the Korean government and local governments have attempted to improve air quality. This study examined the secondary air pollutant contribution in Ulleung Island, Jeju Island, and Baengnyeong Island and compared the differences between them by analyzing the air pollution level and weather conditions in these regions. The weather conditions of the island regions, such as wind speed, precipitation, and sunshine duration, and the average concentration of air pollutants, such as SO₂, NO₂, CO, O₃, PM₁₀, PM_2.5, were examined. The correlation coefficient between air quality factors of each island region and weather conditions was calculated. Regression analysis was conducted by setting primary air pollutants, SO₂, NO₂, and CO as independent variables, and secondary air pollutants, O₃, PM₁₀, and PM_2.5 as dependent variables to identify the regional contribution and impact. Therefore, the government and local governments should establish air quality management for each island region.

• Journal of Hydrogen and New Energy
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• v.16 no.3
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• pp.229-237
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• 2005

A new burner configuration for a compact fuel-cell reformer with a high-temperature air combustion concept was numerically studied. The burner was designed for a 40 $Nm^3/hr$ hydrogen-generated reformer using natural gas-steam reforming method. In order to satisfy the primary requirements for designing a reformer burner (uniform distribution of temperature along the fuel processor walls and minimum heat losses from the reformer), the features of the present burner configuration included 1) a self-regenerative burner for an exhaust-gas-recirculation to apply for the high-temperature air combustion concept, and 2) an annular-type shield for protecting direct contact of flame with the processor walls. For the injection velocities of the recirculated gas of 0.6-2.4 m/s, the recirculated gas temperature of 1000 K, and the recirculated oxygen mole fraction of 4%, the temperature distributions along the processor walls were found uniform within 100 K variation. Thus, the present burner configuration satisfied the requirement for reducing temperature gradients along the processor walls, and consequently demonstrated that the high-temperature air combustion concept could be applied to the practical fuel reformers for use of fuel cells. The uniformity of temperature distribution is enhanced as the amount of the recirculated gas increases.

• Journal of the Korean Geographical Society
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• v.44 no.2
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• pp.105-121
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• 2009

The accurate official map of air temperature does not exist for the Hawaiian Islands due to the limited number of weather stations on the rugged volcanic landscape. To alleviate the major problem of temperature mapping, satellite-measured land surface temperature (LST) data were used as an additional source of sample points. The Moderate Resolution Imaging Spectroradiometer (MODIS) system provides hypertemperal LST data, and LST pixel values that were frequently observed (${\ge}$14 days during a 32-day composite period) had a strong, consistent correlation with air temperature. Systematic grid points with a spacing of 5km, 10km, and 20km were generated, and LST-derived air temperature estimates were extracted for each of the grid points and used as input to inverse distance weighted (IDW) and cokriging methods. Combining temperature data and digital elevation model (DEM), cokriging significantly improved interpolation accuracy compared to IDW. Although a cokriging method is useful when a primary variable is cross-correlated with elevation, interpolation accuracy was sensitively influenced by the seasonal variations of weather conditions. Since the spatial variations of local air temperature are more variable in the wet season than in the dry season, prediction errors were larger during the wet season than the dry season.

• Journal of Korean Society for Atmospheric Environment
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• v.34 no.3
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• pp.418-429
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• 2018

Measurements of 24-hr size-segregated ambient particles were made at an urban site of Gwangju under high pressure conditions occurred in the Korean Peninsula late in March 2018. The aim of this study was to understand the effect of air stagnation on mass size distributions and formation pathways of water-soluble organic and inorganic components. During the study period, the $NO_3{^-}$, $SO_4{^{2-}}$, $NH_4{^+}$, water-soluble organic carbon (WSOC), and humic-like substances(HULIS) exhibited mostly bi-modal size distributions peaking at 1.0 and $6.2{\mu}m$, with predominant droplet modes. In particular, outstanding droplet mode size distributions were observed on March 25 when a severe haze occurred due to stable air conditions and long range transport of aerosol particles from northeastern regions of China. Air stagnation conditions and high relative humidity during the study period resulted in accumulation of primary aerosol particles from local emission sources and enhanced formation of secondary ionic and organic aerosols through aqueous-phase oxidations of $SO_2$, $NO_2$, $NH_3$, and volatile organic compounds, leading to their dominant droplet mode size distributions at particle size of $1.0{\mu}m$. From the size distribution of $K^+$ in accumulation mode, it can be inferred that in addition to the secondary organic aerosol formations, accumulation mode WSOC and HULIS could be partly attributed to biomass burning emissions.

• Transactions of the Korean Society of Automotive Engineers
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• v.19 no.2
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• pp.26-34
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• 2011

Hybrid powertrain systems have been developed to improve the fuel efficiency of internal combustion engines. In the case of a parallel hybrid powertrain system, an engine and a motor are directly coupled. Because of the hardware configuration of the parallel hybrid system, friction and the pumping losses of internal combustion engines always exists. Such losses are the primary factors that result in the deterioration of fuel efficiency in the parallel-type hybrid powertrain system. In particular, the engine operates as a power consumption device during the fuel-cut condition. In order to improve the fuel efficiency for the parallel-type hybrid system, cylinder deactivation (CDA) technology was developed. Cylinder deactivation technology can improve fuel efficiency by reducing pumping losses during the fuel-cut driving condition. In a CDA engine, there are two operating modes: a CDA mode and an SI mode according to the vehicle operating condition. However, during the mode change from CDA to SI, a serious fluctuation of the air-fuel ratio can occur without adequate control. In this study, an air-fuel ratio control algorithm during the mode transition from CDA to SI was proposed. The control algorithm was developed based on the mean value CDA engine model. Finally, the performance of the control algorithm was validated by various engine experiments.

• Ocean and Polar Research
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• v.26 no.1
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• pp.1-10
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• 2004

Ice cliff retreat and sea-ice formation around King Sejong Station in King George Island were analysed and compared with air temperature change. Analysis of 33-year (1969-2001) air temperature records at Bellingshausen Station has revealed regional atmospheric warming, and the increasing rate of air temperature Is equivalent to a warming of $1^{\circ}C$ for 27-year period. Here we present time-series of observations for the areal extent of the ice cliff and ice sheet, showing that they have retreated dramatically in the past 45 years (1956-2001). Retreat of 1,050 m in length of the ice clifr has changed the Marian Cove into a low rectangular form of 4 km in length and 1 to 1.3km in width. The retreat rates have since increased from 6 m/yr of the Primary investigated Period to 54 and 81m/yr in the recent years. Exceptionally, the ice cliff had been advanced of 21m in length for a year between 1987 and 1988 of cold winters. Ice sheet in King George Island also shows a similar decrease, and the decreasing extent is much larger at the southern part of the Main Cove, relatively more exposed to the sun, than at the northern part. Comparing sea-ice formation in winter with air temperature data shows a pattern starting to freeze below $-5^{\circ}C$ and to thaw over $-3^{\circ}C$. It is conclusively estimated that the patterns and magnitudes of ice cliff retreat and sea-ice formation are consistent with fluctuations of the air temperature, and that the recent rapid retreat of ice cliff and less formation of sea-ice are caused especially by the warming trends in autumn accompanied with expansion of summer thawing period.

• Journal of Chest Surgery
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• v.32 no.1
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• pp.38-42
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• 1999

Background: In neonatal respiratory distress syndrome patients, various types of pulmonary air leak contributes to elevate morbity and mortality. Although early surgical interventions can provide better results in several cases, whole clinical outcomes are poor. This study was designed to investigate the clinical aspects of pulmonary air leak in the neonatal respiratory distress syndrome patients and major contributing factors to mortality. Material and Method : We retrospectively evaluated 48 cases of pulmonary air leak in the neonatal respiratory distress syndrome patients from September 1994 to May 1997. Result: There were 15 cases of primary and 33 cases of secondary pulmonary air leakages. The prominent manifestations were pure interstitial emphysema in 19 cases(39.9%) and combined pneumothorax in 19 cases(39.9%). In clinical aspects, normal birth weight was dominant(83.4%), the onset occurred within 24 hours was in 28 cases(58.8%). The pulmonary diseases were meconium aspiration syndrome(25.2%) and hyaline membrane disease(33.2%). The overall hospital mortality was 25.2%, and the majority were hyaline membrane diseases. Conclusion: Although the overral mortality rate of these diseases were high, more detailed studies about immediate treatement, perinatal prevention, intensive care to geriatric problems were needed individually to improve outcomes.

• Journal of the Korean Society of Industry Convergence
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• v.17 no.3
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• pp.103-112
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• 2014

BY the Transformers and reactors, the input electrical energy is converted into magnetic energy. At the end through the magnetic energy was passed at the output parameter. Specially At the flyback transformer or a reactor airgap were designed to contain more magnetic energy. But that work is very difficult for the optimal design. It is that Contradictions are between the length of the Air-gap, Winding inductance, DC bias. As to e Several conflicting conditions in order to determine the optimum Air-gap has a lot of experience and trial & error is necessary. The approach proposed in this paper, the auxiliary winding on the core attached to part of primary core, that by applying a DC voltage has a dramatic effect like Core with designed Air-gap. This inventiveness and advantage is to regulate arbitrarily the Saturation Flux Quantity by the input signal to secondary winding. Accordingly obtained the biggest effect is that increasing limits of the saturation current destined by the material and shape of the conventional core. In other words, that can decreas the size of the transformer and reactor, While maintaining the current saturation capacity. This paper, prove its effect as using the local flux saturation in transformers and reactors for research by the computer program using the finite element method (FEM) simulation, followed by actual experiment to verify

• Journal of Korean Society for Atmospheric Environment
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• v.34 no.4
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• pp.517-533
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• 2018

We utilize the CAMx (Comprehensive Air Quality Model with eXtensions) system and the PSAT (Particulate Source Apportionment Technology) diagnostic tool to determine the $PM_{2.5}$ concentration and to perform its source apportionment in the southeastern region of South Korea. For a year-long simulation, eight local authorities in the region such as Pohang, Daegu, Gyeongju, Ulsan, Busan-Gimhae, Gosung-Changwon, Hadong, and all remaining areas in Gyeongsangnam-do, are selected as source areas based on the emission rates of $NO_x$, $SO_x$, VOC, and primary PM in CAPSS (Clean Air Policy Support System) 2013 emissions inventory. The CAMx-PSAT simulation shows that Pohang has the highest $PM_{2.5}$ self-contribution rate (25%), followed by Hadong (15%) and Busan-Gimhae (14%). With the exception of Pohang, which has intense fugitive dust emissions, other authorities are strongly affected by emissions from their neighboring areas. This may be measured as much as 1 to 2 times higher than that of the self-contribution rate. Based on these estimations, we conclude that the efficiency of emission reduction measures to mitigate $PM_{2.5}$ concentrations in the southeastern region of South Korea can be maximized when the efforts of local or regional emission controls are combined with those from neighboring regions. A comprehensive control policy planning based on the collaboration between neighboring jurisdictional boundaries is required.