• Journal of Preventive Medicine and Public Health
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• 제43권4호
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• pp.352-361
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• 2010

Objectives: This study estimated the annual socioeconomic costs of food-borne disease in 2008 from a societal perspective and using a cost-of-illness method. Methods: Our model employed a comprehensive set of diagnostic disease codes to define food-borne diseases with using the Korea National Health Insurance (KNHI) reimbursement data. This study classified the food borne illness as three types of symptoms according to the severity of the illness: mild, moderate, severe. In addition to the traditional method of assessing the cost-of-illness, the study included measures to account for the lost quality of life. We estimated the cost of the lost quality of life using quality-adjusted life years and a visual analog scale. The direct cost included medical and medication costs, and the non-medical costs included transportation costs, caregiver's cost and administration costs. The lost productivity costs included lost workdays due to illness and lost earnings due to premature death. Results: The study found the estimated annual socioeconomic costs of food-borne disease in 2008 were 954.9 billion won (735.3 billion won-996.9 billion won). The medical cost was 73.4 -76.8% of the cost, the lost productivity cost was 22.6% and the cost of the lost quality of life was 26.0%. Conclusions: Most of the cost-of-illness studies are known to have underestimated the actual socioeconomic costs of the subjects, and these studies excluded many important social costs, such as the value of pain, suffering and functional disability. The study addressed the uncertainty related to estimating the socioeconomic costs of food-borne disease as well as the updated cost estimates. Our estimates could contribute to develop and evaluate policies for food-borne disease.

• 여성건강간호학회지
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• 제15권4호
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• pp.362-371
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• 2009

Purpose: This study was implemented to investigate the level of awareness of osteoporosis among urban women. Methods: A survey was conducted with a sample size of 434 adult females who resided in metropolises in Korea such as Seoul, Gyeonggi-do, Pusan, Gyeongsangnam-do, Kangwondo, Jeju-do and Jeollanam-do. Osteoporosis Awareness Scale was consisted of five areas with total number of 31 questions. The questionnaire's scale was 1 to 4 point, 4 point being the highest understanding level. The collected data were analyzed using descriptive statistics method. Results: The average awareness level of subjects was 2.38 and significant different depending on participants' age, education level, previous encounter with any information about osteoporosis, preventive behavior of osteoporosis, bone mineral density test, fracture history, diet control experience, and regular exercise. In osteoporosis awareness level by five areas, preventive behaviors 2.76 resulted in the highest score and characteristics of osteoporosis 2.51, bone physiology 2.46, improving bone health 2.38, and risk factors 1.80 followed respectively. Conclusion: We should implement bone health programs from a various perspective in order to raise women's osteoporosis awareness. In addition, We need follow-up studies on whether or not the increase on awareness level actually would result in changing in their behavior.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.5999-6004
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• 2012

Measurement of quality of life among prostate cancer patients helps the health care providers to understand the impact of the disease in the patients' own perspective. The main aim of this study is to measure the quality of life among prostate cancer patients at University Malaya Medical Center (UMMC) and Universiti Kebangsaan Malaysia Medical Centre (UKMMC) and to ascertain the association factors for physical coefficient summary (PCS) and mental coefficient summary (MCS). A hospital based, cross sectional study using the Short Form-36 (SF-36) questionnaire was conducted over a period of 6 months. A total of 193 respondents were recruited. Their total quality of life score was $70.1{\pm}14.7$ and the PCS score was lower compared to MCS. The factors associated for PCS were: age, living partner, renal problem, urinary problem of intermittency, dysuria and hematuria. Factors associated for MCS were: age, living partner, renal problem, presenting prostatic specific antigen and urinary problem of intermittency and dysuria. Our prostate cancer patients had moderate quality of life in the physical health components but their mental health was less affected.

• Journal of Preventive Medicine and Public Health
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• 제53권3호
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• pp.189-197
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• 2020

Objectives: Our aim was to answer the following questions: (1) Can mental health variance be partitioned to individual and higher levels (e.g., neighborhood and district); (2) How much (as a percentage) do individual-level determinants explain the variability of mental health at the individual-level; and (3) How much do determinants at the neighborhood- or district-level explain the variability of mental health at the neighborhood- or district-level? Methods: We used raw data from the second round of the Urban Health Equity Assessment and Response Tool in Tehran (in 2012-2013, n=34 700 samples nested in 368 neighborhoods nested in 22 districts) and the results of the official report of Tehran's Center of Studies and Planning (in 2012-2013, n=22 districts). Multilevel linear regression models were used to answer the study questions. Results: Approximately 40% of Tehran residents provided responses suggestive of having mental health disorders (30-52%). According to estimates of residual variance, 7% of mental health variance was determined to be at the neighborhood-level and 93% at the individual-level. Approximately 21% of mental health variance at the individual-level and 49% of the remaining mental health variance at the neighborhood-level were determined by determinants at the individual-level and neighborhood-level, respectively. Conclusions: If we want to make the most effective decisions about the determinants of mental health, in addition to considering the therapeutic perspective, we should have a systemic or contextual view of the determinants of mental health.

• Journal of Preventive Medicine and Public Health
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• 제53권3호
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• pp.205-210
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• 2020

Objectives: Aging is assumed to be accompanied by greater health care expenditures. The objective of this retrospective, bottom-up micro-costing study was to identify and analyze the variables related to increased health care costs for the elderly from the provider's perspective. Methods: The analysis included all elderly inpatients who were admitted in 2017 to a hospital in Tehran, Iran. In total, 1288 patients were included. The Mann-Whitney and Kruskal-Wallis tests were used. Results: Slightly more than half (51.1%) of patients were males, and 81.9% had a partial recovery. The 60-64 age group had the highest costs. Cancer and joint/orthopedic diseases accounted for the highest proportion of costs, while joint/orthopedic diseases had the highest total costs. The surgery ward had the highest overall cost among the hospital departments, while the intensive care unit had the highest mean cost. No statistically significant relationships were found between inpatient costs and sex or age group, while significant associations (p<0.05) were observed between inpatient costs and the type of ward, length of stay, type of disease, and final status. Regarding final status, costs for patients who died were 3.9 times higher than costs for patients who experienced a partial recovery. Conclusions: Sex and age group did not affect hospital costs. Instead, the most important factors associated with costs were type of disease (especially chronic diseases, such as joint and orthopedic conditions), length of stay, final status, and type of ward. Surgical services and medicine were the most important cost items.

• Journal of Preventive Medicine and Public Health
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• 제46권sup1호
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• pp.28-34
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• 2013

Physical activity (PA) professionals and participants recognize enhanced quality of life (QoL) as a benefit of and motivator for PA. However, QoL measures are often problematic and rarely consider the participants' perspective. This paper focuses on recent findings from a larger project on the role of QoL in PA and health promotion. More specifically, we focus on the views of participants and potential participants to better understand the relationship of PA and QoL. In earlier stages of the project we began with a conceptual model of QoL and developed a survey. We now focus on participants' views and ask two questions: 1) what is QoL? and 2) how does PA relate to QoL? We first asked those questions of a large sample of university students and community participants as open-ended survey items, and then asked focus groups of community participants. Overall, participants' responses reflected the multidimensional, integrative QoL model, but the responses and patterns provided information that may not be picked up with typical survey measures. Findings suggest that PA contributes to multiple aspects of QoL, that social and emotional benefits are primary motivators and outcomes for participants, and that the meaning of QoL and PA benefits is subjective and contextualized, varying across individuals and settings. Programs that directly target and highlight the multiple dimensions and integrative QoL, while considering the individual participants and contexts, may enhance both PA motivation and participants' health and QoL.

• IMMUNE NETWORK
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• 제21권1호
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• pp.8.1-8.17
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• 2021

The global crisis caused by the coronavirus disease 2019 (COVID-19) led to the most significant economic loss and human deaths after World War II. The pathogen causing this disease is a novel virus called the severe acute respiratory syndrome coronavirus 2 (SARSCoV-2). As of December 2020, there have been 80.2 million confirmed patients, and the mortality rate is known as 2.16% globally. A strategy to protect a host from SARS-CoV-2 is by suppressing intracellular viral replication or preventing viral entry. We focused on the spike glycoprotein that is responsible for the entry of SARS-CoV-2 into the host cell. Recently, the US Food and Drug Administration/EU Medicines Agency authorized a vaccine and antibody to treat COVID-19 patients by emergency use approval in the absence of long-term clinical trials. Both commercial and academic efforts to develop preventive and therapeutic agents continue all over the world. In this review, we present a perspective on current reports about the spike glycoprotein of SARS-CoV-2 as a therapeutic target.

• 디지털융복합연구
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• 제12권8호
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• pp.369-376
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• 2014

죽음교육의 주체이자 대상인 의료진의 죽음에 대한 스트레스 정도와 수용방식을'병원 공간을 중심으로'분석하여 죽음교육에 활용하고자, 2014년 4월부터 동년 4월30일까지 대전지역 일반인 281명을 대상으로 조사했다. 분석 결과 죽음교육의 필요성에 대해, 죽음교육을 받은 경우 더 중요하다고 생각하였다. 환자가 회불 불가상태인 경우 의료진은 누구에게 알리는가의 물음에 전체적으로는 보호자가 가장 높았으며, 임종하기 적합한 장소로는 살던집이 가장 많았고, 의료기관, 사회복지시설 순으로 나타났다. 이상과 같은 결과를 활용하면 죽음이라는 현상을 이해하고 다룸에 있어 보건의료적 시각과 인문학적 시각, 사회적 시각을 동시에 수용하여 일반인에게 적용할 수 있는 죽음 교육 프로그램 개발을 위한 연구로 죽음준비프로그램을 대중화 일반화를 위한 기초자료로써 의의가 있다고 할 수 있다.

• 정보관리학회지
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• 제41권1호
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• pp.411-438
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• 2024

본 연구는 계량서지학적 분석 방법을 통해 여러 영역으로 나누어진 국내 건강정보 관련 연구를 통합적인 시각으로 보고자 하였다. 이를 위해 한국학술지인용색인 데이터베이스를 통해 2002년부터 2023년까지의 국내 '건강정보' 관련 논문 1,193편을 수집하여 시기별 동향, 학문분야, 지적구조, 키워드 변화 시기를 분석하였다. 분석결과, 건강정보 관련 논문 수는 지속적으로 증가하였으며, 2021년 이후 감소하고 있다. 건강정보 관련 연구의 주요 학문분야는 '의공학', '예방의학/직업환경의학', '법학', '간호학', '문헌정보학', '학제간연구'로 볼 수 있다. 건강정보 관련 연구의 지적구조를 파악하기 위해 단어동시출현분석을 시행하였다. 이후 도출된 네트워크의 구조와 군집파악을 위해 병렬최근접이웃클러스터링 알고리즘을 적용한 결과 '건강정보에 대한 의료공학적 관점'과 '건강정보에 대한 사회과학적 관점'이라는 2개의 대군집을 중심으로 그에 속한 4개의 중군집, 17개의 소군집을 파악할 수 있었다. 학문분야와 키워드의 변화 시기를 추적하기 위해 변곡점 분석을 시도하였으며 공통적으로 2010년과 2011년 사이에 변화가 있는 것으로 나타났다. 마지막으로 평균 출판년도와 단어출현빈도를 통해 전략 다이어그램을 도출하였으며 고빈도 키워드를 '유망', '성장', '성숙' 영역으로 구분하여 제시하였다. 본 연구는 주로 내용분석 중심의 선행연구들과 다르게 여러 가지 계량서지학적 방법을 통해 건강정보 관련 연구영역을 통합적인 시각으로 바라보았다는 데 의의가 있다.

• 대한예방한의학회지
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• 제21권2호
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• pp.1-13
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• 2017

Objectives : This paper serves to explore current trends of systems biology in Traditional Chinese Medicine (TCM) and examine how it may influence the Traditional Korean medicine. Methods : Literature review method was collectively used to classify Introduction to systems biology, diagnosis and syndrome classification of systems biology in TCM perspective, physiotherapy including acupuncture, herbs and formula functions, TCM systems biology, and directions of academic development. Results : The term 'Systems biology' is coined as a combination of systems science and biology. It is a field of study that tries to understand living organism by establishing a theory based on an ideal model that analyzes and predicts the desired output with understanding of interrelationships and dynamics between variables. Systems biology has an integrated and multi-dimensional nature that observes the interaction among the elements constructing the network. The current state of systems biology in TCM is categorized into 4 parts: diagnosis and syndrome, physical therapy, herbs and formulas and academic development of TCM systems biology and its technology. Diagnosis and syndrome field is focusing on developing TCM into personalized medicine by clarifying Kidney yin deficiency patterns and metabolic differences among five patterns of diabetes and analyzing plasma metabolism and biomarkers of coronary heart disease patients. In the field of physical therapy such as acupuncture and moxibustion, researchers discovered the effect of stimulating acupoint ST40 on gene expression and the effects of acupuncture on treating functional dyspepsia and acute ischemic stroke. Herbs and formulas were analyzed with TCM network pharmacology. The therapeutic mechanisms of Si Wu Tang and its series formulas are explained by identifying potential active substances, targets and mechanism of action, including metabolic pathways of amino acid and fatty acid. For the academic development of TCM systems biology and its technology, it is necessary to integrate massive database, integrate pharmacokinetics and pharmacodynamics, as well as systems biology. It is also essential to establish a platform to maximize herbal treatment through accumulation of research data and diseases-specific, or drug-specific network combined with clinical experiences, and identify functions and roles of molecules in herbs and conduct animal-based studies within TCM frame. So far, few literature reviews exist for systems biology in traditional Korean medicine and they merely re-examine known efficacies of simple substances, herbs and formulas. For the future, it is necessary to identify specific mechanisms of working agents and targets to maximize the effects of traditional medicine modalities. Conclusions : Systems biology is widely accepted and studied in TCM and already advanced into a field known as 'TCM systems biology', which calls for the study of incorporating TCM and systems biology. It is time for traditional Korean medicine to acknowledge the importance of systems biology and present scientific basis of traditional medicine and establish the principles of diagnosis, prevention and treatment of diseases. By doing so, traditional Korean medicine would be innovated and further developed into a personalized medicine.